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■ Abbreviation / Long Form : AT1R / Ang II type 1 receptor

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Total Number of Papers: 275
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Abbreviation:   AT1R  (>> Co-occurring Abbreviation)
Long Form:   Ang II type 1 receptor
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2021 Aldosterone and cortisol synthesis regulation by angiotensin-(1-7) and angiotensin-converting enzyme 2 in the human adrenal cortex. APA, dd, DIZE
2021 Angiotensin II biphasically regulates cell differentiation in human iPSC-derived kidney organoids. Ang II, AT2R, RAS
2021 Angiotensin II Induces Oxidative Stress and Endothelial Dysfunction in Mouse Ophthalmic Arteries via Involvement of AT1 Receptors and NOX2. Ang II, CYP450, NOS, ROS
2021 Angiotensin II upregulates RANKL/NFATC1 expression in synovial cells from patients with rheumatoid arthritis through the ERK1/2 and JNK pathways. Ang II, NFATC1, OA, RA, RANKL
2021 Angiotensin-(1-7)-A Potential Remedy for AKI: Insights Derived from the COVID-19 Pandemic. ACE, AKI, Ang, CKD, RAS
2021 AT2 receptor interacting protein 1 (ATIP1) mediates COX-2 induction by an AT2 receptor agonist in endothelial cells. Ang II, ATIP1, HUVECs
2021 Blocking FcγRIIB in Smooth Muscle Cells Reduces Hypertension. Ang II, Igs, SMC
2021 Contrasting Roles of Ang II and ACEA in the Regulation of IL10 and IL1β Gene Expression in Primary SHR Astroglial Cultures. Ang, CB1R, SHR
2021 Crosstalk between the renin-angiotensin system and the endoplasmic reticulum stress in the cardiovascular system: Lessons learned so far. ACE, Ang, ER
10  2021 Dieckol Reduces Muscle Atrophy by Modulating Angiotensin Type II Type 1 Receptor and NADPH Oxidase in Spontaneously Hypertensive Rats. Ang II, DK, ECE, NOX, ROS, SHRs, Treg
11  2021 Effects of Angiotensin II Type 1A Receptor on ACE2, Neprilysin and KIM-1 in Two Kidney One Clip (2K1C) Model of Renovascular Hypertension. ACE2, Ang II, AT1RKO, MAP, NEP
12  2021 Glucagon-like peptide-1 attenuates cardiac hypertrophy via the AngII/AT1R/ACE2 and AMPK/mTOR/p70S6K pathways. ACE2, AMPK, Ang II, AT2R, GLP-1, mTOR
13  2021 Losartan improved hippocampal long-term potentiation impairment induced by repeated LPS injection in rats. Ang II, fEPSP, i.p, LPS, LTP
14  2021 Puerarin exhibits antiinflammatory properties in gunpowder smog-induced acute lung injury in rats via regulation of the renin-angiotensin system and the NFκB signaling pathway. ACE, ALI, Ang II, BALF, IL, RAS, TNF
15  2021 Renal Vascular Response to Angiotensin II Administration in Two Kidneys-One Clip Hypertensive Rats Treated with High Dose of Estradiol: The Role of Mas Receptor. Ang II, MAP, MasR, RAS, RBF, RPP, RVR
16  2021 S-adenosylmethionine upregulates the angiotensin receptor-binding protein ATRAP via the methylation of HuR in NAFLD. Ang II, HuR, NAFLD, OA, SAM
17  2021 Soluble (pro)renin receptor induces endothelial dysfunction and hypertension in mice with diet-induced obesity via activation of angiotensin II type 1 receptor. Ang II, CAP, HUVECs, LOS, RAS
18  2021 Soluble fms-like tyrosine kinase-1 and angiotensin2 target calcitonin gene-related peptide family peptides in maternal vascular smooth muscle cells in pregnancy†. ADM, ADM2, Ang2, cAMP, OASMC, PCR, PE, RAMP, VEGF
19  2021 Spent Hen Muscle Protein-Derived RAS Regulating Peptides Show Antioxidant Activity in Vascular Cells. ACE, ACE2u, Ang, MasR, TNF-alpha, V-F
20  2021 The evolving complexity of the collecting duct renin-angiotensin system in hypertension. Ang I, Ang II, ENaC
21  2021 TLR4 and AT1R mediate blood-brain barrier disruption, neuroinflammation, and autonomic dysfunction in spontaneously hypertensive rats. Ang II, BBB, NTS, PVN, RVLM, SHRs, TLR4, WKYs
22  2021 Update on Angiotensin II Subtype 2 Receptor: Focus on Peptide and Nonpeptide Agonists. Ang II, AT2R, RAS
23  2021 Update on New Aspects of the Renin-Angiotensin System in Hepatic Fibrosis and Portal Hypertension: Implications for Novel Therapeutic Options. ACE, Ang I, Ang II, MrgD, RAS
24  2021 Xiaoxuming Decoction Regulates Vascular Function by Modulating G Protein-Coupled Receptors: A Molecular Docking Study. 5-HT, 5-HT1BR, Ang II, beta2AR, CBF, CHM, GPCRs, UII, UTR, XXMD
25  2020 ADAM17-Mediated Shedding of Inflammatory Cytokines in Hypertension. Ang-II, RAS
26  2020 Alamandine attenuates hepatic fibrosis by regulating autophagy induced by NOX4-dependent ROS. ACE, ACE2, ALA, Ang II, HSCs, MrgD, NAC, NOX, RAS, ROS, siRNA
27  2020 Angiotensin II enhances the proliferation of Natural Killer/T-cell lymphoma cells via activating PI3K/Akt signaling pathway. Ang, NK/T, p-Akt, p-PI3K, PCNA
28  2020 Angiotensin II inhibits osteogenic differentiation of isolated synoviocytes by increasing DKK-1 expression. Ang II, DKK1, NOX, ROS
29  2020 Angiotensin-(1-7) Participates in Enhanced Skeletal Muscle Insulin Sensitivity After a Bout of Exercise. ACE
30  2020 AT1R-Specific Ligand Angiotensin II as a Novel SPECT Agent for Hepatocellular Carcinoma Diagnosis. Ang II, HCC
31  2020 Differential responses of bone to angiotensin II and angiotensin(1-7): beneficial effects of ANG(1-7) on bone with exposure to high glucose. Ang II, SHR
32  2020 Effect of Angiotensin II on Bone Erosion and Systemic Bone Loss in Mice with Tumor Necrosis Factor-Mediated Arthritis. Ang II, RAS, TNF-Tg
33  2020 Endothelial prolyl hydroxylase 2 is necessary for angiotensin II-mediated renal fibrosis and injury. Ang II, ECs, HIF, PHD2, PHD2ECKO, ROS, WT
34  2020 HUANGKUISIWUFANG inhibits pyruvate dehydrogenase to improve glomerular injury in anti-Thy1 nephritis model. ATS, BUN, Ccr, DCA, ECM, HKSWF, RNA-seq, SCr
35  2020 Interplay Between Angiotensin II Type 1 Receptor and Thrombin Receptor Revealed by Bioluminescence Resonance Energy Transfer Assay. Ang II, BRET, GPCRs, HEK293, PAR1, RAS
36  2020 Recent Research Advances in Renin-Angiotensin-Aldosterone System Receptors. Ang II, AT2R, RAAS
37  2020 Similarity and dissimilarity between angiotensin A and angiotensin II in cardiovascular functions in a rat model. Ang, ANP
38  2020 The ACE2-deficient mouse: A model for a cytokine storm-driven inflammation. ACE2, Ang, Ang 1-7, SARS-CoV-2
39  2020 The contribution of chymase-dependent formation of ANG II to cardiac dysfunction in metabolic syndrome of young rats: roles of fructose and EETs. ACE, EETs, HFD, MetS, NO, NOX, sEH, TPPU
40  2020 The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone. Ang II, AT2R, ATR
41  2020 The Impact of Renal Denervation on the Progression of Heart Failure in a Canine Model Induced by Right Ventricular Rapid Pacing. ACE, Ang II, BNP, HF, HF, NE, RAS, RDN, RDN, TGF-beta1
42  2020 TLR4/MyD88/NF-κB Signaling in the Rostral Ventrolateral Medulla Is Involved in the Depressor Effect of Candesartan in Stress-Induced Hypertensive Rats. Ang II, i.c.v, IL-1beta, MyD88, NF, RVLM, SIH, SIHR, TLR4, TNF-alpha
43  2020 Two hits to the renin-angiotensin system may play a key role in severe COVID-19. ACE, RAS, SARS-CoV-2
44  2019 Angiotensin 1 receptor antagonist attenuates acute kidney injury-induced cognitive impairment and synaptic plasticity via modulating hippocampal oxidative stress. AKI, Ang
45  2019 Angiotensin II and tumor necrosis factor-alpha stimulate the growth, migration and invasion of BEL-7402 cells via down-regulation of GRK2 expression. Ang II, BLTs, CCK-8, ELISA, FCM, GRK2, HCC, TNF-alpha, TNFR1
46  2019 Angiotensin II down-regulates transferrin receptor 1 and ferroportin 1 expression in Neuro-2a cells via activation of type-1 receptor. Ang II, AT2R, FPN1, IRPs, Nrf2, TfR1
47  2019 AT1 receptors in the subfornical organ modulate arterial pressure and the baroreflex in two-kidney, one-clip hypertensive rats. Ang II, HR, MAP, RSNA, SFO, Sham
48  2019 AT1R-AT2R-RXFP1 Functional Crosstalk in Myofibroblasts: Impact on the Therapeutic Targeting of Renal and Cardiac Fibrosis. Ang II, RXFP1
49  2019 Central blockade of the AT1 receptor attenuates pressor effects via reduction of glutamate release and downregulation of NMDA/AMPA receptors in the rostral ventrolateral medulla of rats with stress-induced hypertension. AMPA, Ang II, HR, MAP, NE, NMDA, RVLM, SIH, SIHR
50  2019 Downregulation of AT2R decreases the responsiveness of BKCa channels to angiotensin II in patients with hypertension. Ang II, HP, MSMCs, NP, SMCs
51  2019 Fetal programming and the angiotensin-(1-7) axis: a review of the experimental and clinical data. ACE, Ang, BP, MasR
52  2019 Influenza A virus mimetic nanoparticles trigger selective cell uptake. Ang I, Ang II, NPs
53  2019 Intermedin in Paraventricular Nucleus Attenuates Ang II-Induced Sympathoexcitation through the Inhibition of NADPH Oxidase-Dependent ROS Generation in Obese Rats with Hypertension. AM, Ang II, APO, BP, CRLR, IMD, MAP, MAPK/ERK, PVN, RAMP2, ROS, RSNA, SNA
54  2019 Liraglutide attenuates cardiac remodeling and improves heart function after abdominal aortic constriction through blocking angiotensin II type 1 receptor in rats. AAC, Ang II, GLP-1
55  2019 Losartan protects against myocardial ischemia and reperfusion injury via vascular integrity preservation. Ang II, CAD, I/R, VE-cadherin, VEGFR2
56  2019 Parental Renovascular Hypertension-Induced Autonomic Dysfunction in Male Offspring Is Improved by Prenatal or Postnatal Treatment With Hydrogen Sulfide. BP
57  2019 Risk and severity of psoriasis vulgaris in relation to angiotensin II type 1 receptor gene polymorphism and metabolic syndrome. Ang II, PASI, PCR, RFLP
58  2019 Roles of I2PP2A in the downregulation of eNOS Ser1177 phosphorylation by angiotensin II-activated PP2A. Ang II, CAN, ED, eNOS, HUVECs, NO, PP2A
59  2019 Soluble RAGE attenuates AngII-induced endothelial hyperpermeability by disrupting HMGB1-mediated crosstalk between AT1R and RAGE. Ang II, HUVECs, RAGE, sRAGE
60  2019 Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor beta1 Fibrogenic Axis. ACE, AGT, alpha-SMA, CFs, MFs, STA
61  2019 The renin-angiotensin system: going beyond the classical paradigms. ACE2, AT2R, RAS
62  2019 The role of monocyte chemotactic protein-induced protein 1 (MCPIP1) in angiotensin II-induced macrophage apoptosis and vulnerable plaque formation. ACS, AMPK, Ang II, ER, MCPIP1
63  2019 Tsantan Sumtang attenuated chronic hypoxia-induced right ventricular structure remodeling and fibrosis by equilibrating local ACE-AngII-AT1R/ACE2-Ang1-7-Mas axis in rat. ACE, ACE2, Ang 1-7, Ang II, CPA, ELISA, HE, HPAH, HR, Mas, mPAP, PSR, RV, RVHI, RVSP, SD, TL
64  2019 Upregulation of AT1 Receptor Mediates a Pressor Effect Through ROS-SAPK/JNK Signaling in Glutamatergic Neurons of Rostral Ventrolateral Medulla in Rats With Stress-Induced Hypertension. Ang II, ERK, i.c.v, MABP, MAPK, NADPH, ROS, RVLM, SAPK/JNK, SIHR
65  2018 Activation of Bone Marrow-Derived Cells Angiotensin (Ang) II Type 1 Receptor by Ang II Promotes Atherosclerotic Plaque Vulnerability. 2K1C, Ang, BM
66  2018 Angiotensin (1-7) inhibits arecoline-induced migration and collagen synthesis in human oral myofibroblasts via inhibiting NLRP3 inflammasome activation. ACE, Ang II, NLRs, NOX4, OSF, ROS, siRNA
67  2018 Angiotensin 1-7 ameliorates 6-hydroxydopamine lesions in hemiparkinsonian rats through activation of MAS receptor/PI3K/Akt/BDNF pathway and inhibition of angiotensin II type-1 receptor/NF-kappaB axis. Ang, DA, MasR, PD, TH
68  2018 Angiotensin II Attenuates the Bioactivities of Human Endothelial Progenitor Cells via Downregulation of beta2-Adrenergic Receptor. Ang II, hEPCs, RAS
69  2018 Angiotensin II increases angiogenesis by NF-kappaB-mediated transcriptional activation of angiogenic factor AGGF1. AGGF1, Ang II, RELA, siRNAs
70  2018 Angiotensin II promotes pulmonary metastasis of melanoma through the activation of adhesion molecules in vascular endothelial cells. Ang II, RAS
71  2018 Angiotensin II Suppresses Rev-erbalpha Expression in THP-1 Macrophages via the Ang II Type 1 Receptor/Liver X Receptor alpha Pathway. Ang II, LXRalpha, PPARgamma, siRNA
72  2018 Angiotensin II upregulates CYP4A isoform expression in the rat kidney through angiotensin II type 1 receptor. 20-HETE, Ang II, CO, OM
73  2018 Angiotensin receptor blocker, losartan ameliorates neuroinflammation and behavioral consequences of lipopolysaccharide injection. Ang II, CAT, FST, i.p, LPS, MDA, NO, PA, SOD, SPT
74  2018 Angiotensin-converting enzyme insertion/deletion (rs106180) and angiotensin type 1 receptor A1166 C (rs106165) genotypes and psoriasis: Correlation with cellular immunity, lipid profile, and oxidative stress markers. ACE, Ang, ARE, MDA, PCR, SOD, VAP
75  2018 Blood Pressure-Independent Effect of Olmesartan on Albuminuria in Mice Overexpressing Renin. Ang, HYD, NOX, OLM, ROS, SBP, UAE, WT
76  2018 BML-111, a lipoxin receptor agonist, protects against acute injury via regulating the renin angiotensin-aldosterone system. ACE, ACE2, Ang 1-7, Ang II, LXs, MPO, RAAS
77  2018 Brain Renin-Angiotensin System Blockade Attenuates Methamphetamine-Induced Hyperlocomotion and Neurotoxicity. Ang II, BBB, D3R, METH, RAS
78  2018 Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog. Ang II, AT2R, GPCRs
79  2018 Exercise Protects Against Defective Insulin Signaling and Insulin Resistance of Glucose Transport in Skeletal Muscle of Angiotensin II-Infused Rat. ACE, Ang II, AS160, IR, IRS-1, JNK, MasR, VWR
80  2018 Glial Cells Are Involved in ANG-II-Induced Vasopressin Release and Sodium Intake in Awake Rats. ANG-II, CVOs, FCt, HACc, icv, MAP, OT
81  2018 Magnolol ameliorates pneumonectomy and monocrotaline-induced pulmonary arterial hypertension in rats through inhibition of angiotensin II and endothelin-1 expression. ACE, Ang II, ET-1, PAH, RV
82  2018 MAPK/AP-1 pathway activation mediates AT1R upregulation and vascular endothelial cells dysfunction under PM2.5 exposure. ACE, Ang II, CV, PM
83  2018 Modulation of the renin-angiotensin system in white adipose tissue and skeletal muscle: focus on exercise training. ACE, Ang, ExT, MasR, WAT
84  2018 Prenatal dexamethasone and postnatal high-fat diet have a synergistic effect of elevating blood pressure through a distinct programming mechanism of systemic and adipose renin-angiotensin systems. ACE1, AGT, Ang, AT2R, BP, DEX, HF, MasR, RAS
85  2018 Role of the renin-angiotensin system in hepatic fibrosis and portal hypertension. ACE, Ang, RAS
86  2018 Short-term Heat Exposure Promotes Hippocampal Neurogenesis via Activation of Angiotensin II Type 1 Receptor in Adult Rats. Ang II, VEGF
87  2018 Targeted Ablation of Distal Cerebrospinal Fluid-Contacting Nucleus Alleviates Renal Fibrosis in Chronic Kidney Disease. ACE, ACE2, aCSF, AGT, CB-SAP, CKD, dCSF-CNs, i.c.v, MCP-1, PVN, RAS, RVLM, SFO, TH
88  2018 Telmisartan inhibits NSCLC A549 cell proliferation and migration by regulating the PI3K/AKT signaling pathway. Ang II, NSCLC, p-Akt
89  2018 The angiotensin type 2 receptor in the human adrenocortical zona glomerulosa and in aldosterone-producing adenoma: low expression and no functional role. Ang II, APA, RAS
90  2017 ACE-2/Ang1-7/Mas cascade mediates ACE inhibitor, captopril, protective effects in estrogen-deficient osteoporotic rats. Ang II, ICP-MS, OPG, RANKL, RAS
91  2017 Angiotensin (1-7) ameliorates the structural and biochemical alterations of ovariectomy-induced osteoporosis in rats via activation of ACE-2/Mas receptor axis. ACE-2, OPG, RANKL, RAS
92  2017 Angiotensin II induces monocyte chemoattractant protein‑1 expression by increasing reactive oxygen species‑mediated activation of the nuclear factor‑kappaB signaling pathway in osteoblasts. Ang II, NAC, NF, PDTC, ROS
93  2017 Biased agonism/antagonism at the AngII-AT1 receptor: Implications for adrenal aldosterone production and cardiovascular therapy. Ang II, ARBs, GPCR, SAR
94  2017 Candesartan prevents resiniferatoxin-induced sensory small-fiber neuropathy in mice by promoting angiotensin II-mediated AT2 receptor stimulation. ACE, Ang II, AT2R, RAS, SFN
95  2017 Comparative effects of angiotensin II and angiotensin-(4-8) on blood pressure and ANP secretion in rats. ACE, Ang II, Angs, ANP, PKC
96  2017 Current topics in angiotensin II type 1 receptor research: Focus on inverse agonism, receptor dimerization and biased agonism. Ang II, GPCR
97  2017 Effects of moderate‑intensity endurance exercise on angiotensin II and angiotensin II type I receptors in the rat heart. Ang II
98  2017 MAPK activation patterns of AT1R and CB1R in SHR versus Wistar astrocytes: Evidence of CB1R hypofunction and crosstalk between AT1R and CB1R. ACEA, Ang, CB1R, MAPKs, p-CB1R, SHRs
99  2017 Pathologic Roles of Receptor-Associated Prorenin System in Idiopathic Epiretinal Membrane. iERM, RAPS, RAS
100  2017 Prorenin receptor (PRR)-mediated NADPH oxidase (Nox) signaling regulates VEGF synthesis under hyperglycemic condition in ARPE-19 cells. ACE, Ang II, NOX, PEG, PRR, ROS, siRNA, SOD, VEGF