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■ Abbreviation / Long Form : ATF2 / activating transcription factor 2

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Total Number of Papers: 363
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Abbreviation:   ATF2  (>> Co-occurring Abbreviation)
Long Form:   activating transcription factor 2
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No. Year Title Co-occurring Abbreviation
2022 Activating transcription factor 2 (AccATF2) regulates tolerance to oxidative stress in Apis cerana cerana. AccATF2, bZIP, MDA
2022 Activating transcription factor 2 promotes the progression of hepatocellular carcinoma by inducing the activation of the WHSC1-mediated TOP2A/PI3K/AKT axis. HCC, WHSC1
2022 Adapalene induces adipose browning through the RARbeta-p38 MAPK-ATF2 pathway. AD, DIO, MAPK, RAR
2022 Annexin A7 and JNK knockdown suppress the lymphatic metastasis potential of hepatocellular carcinoma cells: Possible contributions of ATF2 and sequence-related lncRNA NONMMUT114121.1. ANXA7, HCC, JNK, lnc, LNM
2022 ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2. CRC, KO, TROP2
2022 Butorphanol reduces the neuronal inflammatory response and apoptosis via inhibition of p38/JNK/ATF2/p53 signaling. LPS, SCI
2022 Changes of signaling molecules in the axotomized rat facial nucleus. CREB, ERK, IEGs, JNK, MAPKs, pCREB
2022 CircFN1 upregulation initiated oxidative stress-induced apoptosis and inhibition of proliferation and migration in trophoblasts via circFN1-miR-19a/b-3p-ATF2 ceRNA network. ceRNA, MDA, miR, PE, ROC, SOD
2022 CircRNF121 knockdown suppresses the progression of cervical cancer by regulating miR-153-3p/ATF2 axis and wnt/beta-catenin pathway. CC, circRNAs, circRNF121, EMT
10  2022 GLUT3 Promotes Epithelial-Mesenchymal Transition via TGF-beta/JNK/ATF2 Signaling Pathway in Colorectal Cancer Cells. alpha-SMA, CRC, EMT, GLUT, JNK, PAI-1, TGF-beta, ZEB1
11  2022 Hepatocyte-derived MASP1-enriched small extracellular vesicles activate HSCs to promote liver fibrosis. ARRB1, EVs, MAPK, MASP1
12  2022 lncRNA PINK1-AS Aggravates Cerebral Ischemia/Reperfusion Oxidative Stress Injury through Regulating ATF2 by Sponging miR-203. CI/R, PINK1-AS
13  2022 Low-dose aspirin may prevent preeclampsia by inhibiting the expression of ATF2. ---
14  2022 Mosloflavone-Resveratrol Hybrid TMS-HDMF-5z Exhibits Potent In Vitro and In Vivo Anti-Inflammatory Effects Through NF-kappaB, AP-1, and JAK/STAT Inactivation. AP-1, COX-2, IFN-beta, IKK, IL, iNOS, LPS, MAPK, MK2, NF-kappaB, TAK1, TNF-alpha
15  2022 MYBPC1 is a key regulator for laryngeal carcinoma formation. MYBPC1
16  2022 NEDD4L represses prostate cancer cell proliferation via modulating PHF8 through the ubiquitin-proteasome pathway. NEDD4L, PC, PCCs
17  2022 Nuciferine attenuates lipopolysaccharide-stimulated inflammatory responses by inhibiting p38 MAPK/ATF2 signaling pathways. AP, COX, IkappaB, IKK, IL, iNOS, LPS, MAPK, NF, NO, PGE2, TNF
18  2022 Overexpression of Activating Transcription Factor-2 (ATF-2) Activates Wnt/Ca2+ Signaling Pathways and Promotes Proliferation and Invasion in Non-Small-Cell Lung Cancer. NSCLC
19  2022 Protein disulfide-isomerase A3 knockdown attenuates oxidized low-density lipoprotein-induced oxidative stress, inflammation and endothelial dysfunction in human umbilical vein endothelial cells by downregulating activating transcription factor 2. HUVECs, ox-LDL, PDIA3
20  2022 Shexiang Baoxin Pill Regulates Intimal Hyperplasia, Migration, and Apoptosis after Platelet-Derived Growth Factor-BB-Stimulation of Vascular Smooth Muscle Cells via miR-451. BrdU, CCK-8, PDGF, PI, VSMCs
21  2022 The two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context. ---
22  2022 Tonifying-Qi-and-Detoxification Decoction attenuated injuries of colon and lung tissues in ulcerative colitis rat model via regulating NF-kappaB and p38MAPK pathway. AECII, HE, IHC, NC, NF-kappaB, qRT-PCR, TEM, TQDD, UC
23  2021 A Novel Small Peptide H-KI20 Inhibits Retinal Neovascularization Through the JNK/ATF2 Signaling Pathway. anti-VEGF, HRECs, JNK2
24  2021 ATF2 accelerates the invasion and metastasis of hepatocellular carcinoma through targeting the miR-548p/TUFT1 axis. HCC
25  2021 ATF2-Induced Overexpression of lncRNA LINC00882, as a Novel Therapeutic Target, Accelerates Hepatocellular Carcinoma Progression via Sponging miR-214-3p to Upregulate CENPM. HCC
26  2021 C-type natriuretic peptide promotes adipogenic differentiation of goat adipose-derived stem cells via cGMP/PKG/ p38 MAPK signal pathway. ADSCs, CNP, MK2, NPR-B, p38 MAPK, PGC-1alpha, UCP1
27  2021 Combination of tetrandrine and 3-n-butylphthalide protects against cerebral ischemia-reperfusion injury via ATF2/TLR4 pathway. CI, I/R, NBP, TLR4, TTD
28  2021 Combined De-Repression of Chemoresistance Associated Mitogen-Activated Protein Kinase 14 and Activating Transcription Factor 2 by Loss of microRNA-622 in Hepatocellular Carcinoma. HCC, MAPK14
29  2021 Cytochrome P450 2F2 (CYP2F2) negatively regulates browning in 3T3-L1 white adipocytes. beta3-AR, CYP2F2, p38 MAPK, PGC-1alpha, PKA, PRDM16, UCP1
30  2021 Decoding Cinnabarinic Acid-Specific Stanniocalcin 2 Induction by Aryl Hydrocarbon Receptor. AhR, CA, Dot1l, STC2, TCDD
31  2021 Endoplasmic Reticulum Stress Induces CAP2 Expression Promoting Epithelial-Mesenchymal Transition in Liver Cancer Cells. CAP2, EMT, ER, PKCepsilon
32  2021 G-Protein-coupled Estrogen Receptor 1 Agonist G-1 Perturbs Sunitinib Resistance-related Phosphoproteomic Signatures in Renal Cell Carcinoma. GPER1, PI3K-AKT, RCC
33  2021 Hepatic Mitochondrial SAB Deletion or Knockdown Alleviates Diet-Induced Metabolic Syndrome, Steatohepatitis, and Hepatic Fibrosis. control-ASO, HFHC, JNK, MAPK, NAFL, p-ATF2, p-JNK
34  2021 Hydrogen sulfide of air induces macrophage extracellular traps to aggravate inflammatory injury via the regulation of miR-15b-5p on MAPK and insulin signals in trachea of chickens. DUSP1, GO, KEGG, METs, MPO
35  2021 LncRNA GAS5 enhances radiosensitivity of hepatocellular carcinoma and restricts tumor growth and metastasis by miR-144-5p/ATF2. DLR, GAS5, HCC, RIP
36  2021 Long non‑coding RNA ZSCAN16‑AS1 promotes the malignant properties of hepatocellular carcinoma by decoying microRNA‑451a and consequently increasing ATF2 expression. HCC, lncRNAs
37  2021 MARCH6 promotes hepatocellular carcinoma development through up-regulation of ATF2. HCC, MARCH6
38  2021 Micro-RNA-451 Reduces Proliferation of B-CPAP Human Papillary Thyroid Cancer Cells by Downregulating Expression of Activating Transcription Factor 2. 3'UTR, miRNAs, mRNA, PTC
39  2021 Monocyte-released HERV-K dUTPase engages TLR4 and MCAM causing endothelial mesenchymal transition. dUTPase, EndMT, EVs, MCAM, PA, PAECs, PAH
40  2021 Protective effect of SIRT6 on cholesterol crystal-induced endothelial dysfunction via regulating ACE2 expression. Ang, CC, CVD, eNOS, HUVECs, NO
41  2021 Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia. LPS, PKM2
42  2021 Targeting Long Non-Coding RNA TTN-AS1 Suppresses Bladder Cancer Progression. BC, DFS, RT-PCR, TTN-AS1
43  2021 Tumor Necrosis Factor-alpha utilizes MAPK/NFkappaB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway. 25-HC, C25H, FAK, TNF
44  2020 6'-O-galloylpaeoniflorin regulates proliferation and metastasis of non-small cell lung cancer through AMPK/miR-299-5p/ATF2 axis. AMPK, GPF, NSCLC, pAMPK, UTR
45  2020 Activating transcription factor 2 (ATF2) negatively regulates the expression of antimicrobial peptide genes through tumor necrosis factor (TNF) in Macrobrachium nipponense. TNF
46  2020 Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer. ---
47  2020 D-serine Ameliorates Motor and Cognitive Impairments in beta-amyloid 1-42 Injected Mice by Inhibiting JNK Signaling Pathway. AD, BE, DAAO, GFAP, JNK, NMDAR1, p-JNK
48  2020 Dichotomous engagement of HDAC3 activity governs inflammatory responses. HDACs
49  2020 Exosomal microRNA-26b-5p down-regulates ATF2 to enhance radiosensitivity of lung adenocarcinoma cells. LUAD, miR-26b-5p
50  2020 Indomethacin decreases insulin secretion by reducing KCa3.1 as a biomarker of pancreatic tumor and causes apoptotic cell death. GLUT2, IR
51  2020 M2 Macrophage-Derived Exosomal lncRNA AFAP1-AS1 and MicroRNA-26a Affect Cell Migration and Metastasis in Esophageal Cancer. EC, lncRNAs, miR-26a
52  2020 Mechanisms underlying the promotion of osteosarcoma cell proliferation and invasion by lncRNA PBB12. KLF4, lncRNA
53  2020 Mechano growth factor pretreatment yield mechanical stimuli induced cell stress responses in ligament fibroblasts of osteoarthritis via activating ATF-2. MGF, OA-LFs
54  2020 miR-181a and miR-203 inhibit migration and invasion of laryngeal carcinoma cells by interacting with ATF2. LC, miRNAs, RIP
55  2020 miR-602 Mediates the RASSF1A/JNK Pathway, Thereby Promoting Postoperative Recurrence in Nude Mice with Liver Cancer. JNK, RASSF1A
56  2020 miRNA profiling of biliary intraepithelial neoplasia reveals stepwise tumorigenesis in distal cholangiocarcinoma via the miR-451a/ATF2 axis. BilIN, dCCA
57  2020 Mycosporine-like amino acids stimulate hyaluronan secretion by up-regulating hyaluronan synthase 2 via activation of the p38/MSK1/CREB/c-Fos/AP-1 axis. CREB, ERK, HA, HAS2, JNK, MAAs, MAPK, MEK, MSK1
58  2020 Negative regulation of IL-8 in human astrocytes depends on beta-catenin while positive regulation is mediated by TCFs/LEF/ATF2 interaction. ---
59  2020 PNU-120596, a positive allosteric modulator of alpha7 nicotinic acetylcholine receptor, directly inhibits p38 MAPK. alpha7nAChR, MAPK, MLA, PAM
60  2020 SET8 participates in lipopolysaccharide-mediated BV2 cell inflammation via modulation of TICAM-2 expression. LPS, TICAM-2
61  2020 SpATF2 participates in maintaining the homeostasis of hemolymph microbiota by regulating dual oxidase expression in mud crab. MAPK, RNAi
62  2020 Sprouty2 Inhibits Migration and Invasion of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Down-regulating ATF2 Expression and Phosphorylation. RA, RA-FLS, Spry2
63  2020 The interplay between ATF2 and NEAT1 contributes to lung adenocarcinoma progression. AP-1, LUAD
64  2020 The Ras-ERK signaling pathway regulates acetylated activating transcription factor 2 via p300 in pancreatic cancer cells. ChIP, ERK, MDM2
65  2020 The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation. BAT
66  2020 Ubiquitin-specific protease 14 promotes prostate cancer progression through deubiquitinating the transcriptional factor ATF2. USP14
67  2019 A temperature-dependent conformational shift in p38alpha MAPK substrate-binding region associated with changes in substrate phosphorylation profile. HDX-MS, MAPK, MK2, STAT1alpha, TNF-alpha
68  2019 CID-6033590 inhibits p38MAPK pathway and induces S-phase cell cycle arrest and apoptosis in DU145 and PC-3 cells. HSP27, P-p38, PARP
69  2019 Deficiency in intestinal epithelial Reg4 ameliorates intestinal inflammation and alters the colonic bacterial composition. DSS, IF, IL-6, Reg4, STAT3, TNF-alpha
70  2019 Discovery of the Anti-Tumor Mechanism of Calycosin Against Colorectal Cancer by Using System Pharmacology Approach. ABCG2, BRCA1, CC, CRC, CYP19A1, DisGeNET, EGFR, ESR1, ESR2, FOXA1, PPI
71  2019 ERK1/ATF-2 signaling axis contributes to interleukin-1beta-induced MMP-3 expression in dermal fibroblasts. ECM, ERK, MMPs
72  2019 GDF5 Promotes White Adipose Tissue Thermogenesis via p38 MAPK Signaling Pathway. FABP4, GDF5, HFD, MAPK, sWAT, Tg
73  2019 Identification of biomarkers associated with the recurrence of osteosarcoma using ceRNA regulatory network analysis. ce, GEO, GSEA, lnc, mi, PPM1B, RAP1B, SNHG1
74  2019 Iguratimod Inhibits the Aggressiveness of Rheumatoid Fibroblast-Like Synoviocytes. CETSA, IL-6, JNK, MAPK, MMPs, RA-FLSs
75  2019 Protective Function of Mitogen-Activated Protein Kinase Phosphatase 5 in Aging- and Diet-Induced Hepatic Steatosis and Steatohepatitis. CIDEA, HFD, KO, MAPK, PPARgamma, WT
76  2019 Quercetin Inhibits the Production of IL-1beta-Induced Inflammatory Cytokines and Chemokines in ARPE-19 Cells via the MAPK and NF-kappaB Signaling Pathways. CREB, ERK, ICAM-1, IKK, IL-1beta, JNK, MAPKs, MCP-1, MMP-9, NF, sICAM-1, TNF-alpha
77  2019 The activating transcription factor 2: an influencer of cancer progression. CRC
78  2019 The role of NF-kappaB-mediated JNK pathway in cognitive impairment in a rat model of sleep apnea. CIH, IL-6, iNOS, JNK, MDA, NF-kappaB, NS, SA, SH, SOD, TNF-alpha
79  2019 TRAF6-p38/JNK-ATF2 axis promotes microglial inflammatory activation. CNS
80  2018 Association between the rs7583431 single nucleotide polymorphism close to the activating transcription factor 2 gene and the analgesic effect of fentanyl in the cold pain test. SNPs
81  2018 ATF2, but not ATF3, participates in the maintenance of nerve injury-induced tactile allodynia and thermal hyperalgesia. ---
82  2018 Effects of exercise in a cold environment on transcriptional control of PGC-1alpha. CREB, ERRalpha, MEF2A, NRF1
83  2018 Hippocampal CA1 betaCaMKII mediates neuroinflammatory responses via COX-2/PGE2 signaling pathways in depression. AAV, betaCaMKII, COX, CUMS, LPS, MAPK, PGE2
84  2018 Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring. CREB3L3, Ern2, Hspa4l, IUGR, Mapk10, qPCR, UPR
85  2018 miR-144-5p Enhances the Radiosensitivity of Non-Small-Cell Lung Cancer Cells via Targeting ATF2. NSCLC
86  2018 MiR-451a suppressed cell migration and invasion in non-small cell lung cancer through targeting ATF2. NSCLC, qRT-PCR
87  2018 miRNA-451a regulates RPE function through promoting mitochondrial function in proliferative diabetic retinopathy. 4-HNE, miR-451a, PDR
88  2018 Proprotein convertase subtilisin/kexin type 9 inhibits interferon beta expression through interacting with ATF-2. IFN, PCSK9
89  2018 Recovery of miR-139-5p in Ovarian Cancer Reverses Cisplatin Resistance by Targeting C-Jun. Bcl-xL, miRNAs
90  2018 Regulation by Pink1 on the mitochondrial dysfunction in endothelial cells post the hypoxia mimetic agent CoCl2 treatment. NSCLC, qRT-PCR
91  2018 Shotgun Proteomics and Quantitative Pathway Analysis of the Mechanisms of Action of Dehydroeffusol, a Bioactive Phytochemical with Anticancer Activity from Juncus effusus. DHE, JNK
92  2018 Silencing activating transcription factor 2 promotes the anticancer activity of sorafenib in hepatocellular carcinoma cells. HCC, siRNA, TNF
93  2018 Soluble syntaxin 3 functions as a transcriptional regulator. ETV4
94  2018 The involvement of p38MAPK in the rat model of lower-extremity arterial ischemia-reperfusion injury. p38 MAPK, SD, TUNEL
95  2018 Transcriptional activation of miR-320a by ATF2, ELK1 and YY1 induces cancer cell apoptosis under ionizing radiation conditions. IR, MAPK, XIAP, YY1
96  2018 Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIdelta expression in the aged atrium. JNK, JNK2
97  2017 Alpha-1-antitrypsin suppresses oxidative stress in preeclampsia by inhibiting the p38MAPK signaling pathway: An in vivo and in vitro study. AAT, CCK-8, ChIP, ELISA, MDA, NP, p38 MAPK, PE, qRT-PCR, ROS, SOD, STAT1, TUNEL
98  2017 ATF2 partly mediated the expressions of proliferative factors and inhibited pro-inflammatory factors' secretion in arsenite-treated human uroepithelial cells. iAs
99  2017 ATF2, a paradigm of the multifaceted regulation of transcription factors in biology and disease. ---
100  2017 Autocrine parathyroid hormone-like hormone promotes intrahepatic cholangiocarcinoma cell proliferation via increased ERK/JNK-ATF2-cyclinD1 signaling. ChIP, ERK, ICC, IHC, JNK, PTHLH