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■ Abbreviation / Long Form : ATF / activating transcription factor

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Total Number of Papers: 355
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Abbreviation:   ATF  (>> Co-occurring Abbreviation)
Long Form:   activating transcription factor
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No. Year Title Co-occurring Abbreviation
2022 Emerging roles of activating transcription factor (ATF) family members in tumourigenesis and immunity: Implications in cancer immunotherapy. ---
2022 NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria. ANF, LEF1, NOX4, Nrf2, SIRT1, TCF
2021 1, 8-cineole protects against ISO-induced heart failure by inhibiting oxidative stress and ER stress in vitro and in vivo. CHOP, ISO, PERK, ROS
2021 Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response‑induced upregulation of CHAC1 expression. CHAC1, DHA, PLC, SLC, UPR, XBP1
2021 Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism. HDL
2021 In vivo screen identifies a SIK inhibitor that induces β cell proliferation through a transient UPR. LUCCI, SIKs, UPR
2021 IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 Activation. ER, IL, IRE, KSHV, PEL, PERK, UPR, VEGF
2021 Microcystin-LR induces ferroptosis in intestine of common carp (Cyprinus carpio). ER, GPx, MC-LR
2021 Role of indoleamine 2,3-dioxygenase in ischemia-reperfusion injury of renal tubular epithelial cells. AhR, GCN2K, RPTECs
10  2021 Swallowing dysfunction following radiation to the rat mylohyoid muscle is associated with sensory neuron injury. ---
11  2021 The Role of the CREB Protein Family Members and the Related Transcription Factors in Radioresistance Mechanisms. CREB
12  2021 TLR4 Antagonism Reduces Movement-Induced Nociception and ATF-3 Expression in Experimental Osteoarthritis. DAMPs, DRG, MIA, OA, PAMPs, TLR4, TLR4
13  2021 Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction. CHOP, EF, ER, FS, GRP, LV, PERK, TUNEL, UPR, XBP
14  2020 A Review of the Pharmacological Properties of Psoralen. AChE, AP-1, ASK1, BMP, CHOP, HPA, IRE1, JNK, MMPs, P-gp, PERK, pol, PPARgamma, TCM, TGF-beta, TNF-alpha
15  2020 Acetaldehyde suppresses HBV-MHC class I complex presentation on hepatocytes via induction of ER stress and Golgi fragmentation. AGS, CTLs, ER, HBV
16  2020 Atf-6 Regulates Lifespan through ER-Mitochondrial Calcium Homeostasis. ER, UPRER
17  2020 Designed Artificial Transcription Factors Inhibit Hepatitis B Virus Transcription in HepG2.2.15 Cells. EMSA, HBcAg, HBeAg, HBV
18  2020 Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78 (Glucose-Regulated Protein, 78 kDa)-Loaded Extracellular Vesicles. ALP, BSP, ER, EV, PKR, SMPD3, VSMCs
19  2020 Long Noncoding RNA HITTERS Protects Oral Squamous Cell Carcinoma Cells from Endoplasmic Reticulum Stress-Induced Apoptosis via Promoting MRE11-RAD50-NBS1 Complex Formation. DDR, ER, lncRNAs, OSCC, XBP1
20  2020 Nrf2 and Ferroptosis: A New Research Direction for Neurodegenerative Diseases. BECN1, RCD
21  2020 Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324. ERS, GRP78, IRE1alpha, lncRNAs, MI, miR, TM
22  2020 Protective effects of pterostilbene against hepatic damage, redox imbalance, mitochondrial dysfunction, and endoplasmic reticulum stress in weanling piglets. ATP, ER, PT, RSV
23  2020 The Multifaceted Output of c-Jun Biological Activity: Focus at the Junction of CD8 T Cell Activation and Exhaustion. AP-1, bZIP, JDP2
24  2019 CRBN knockdown mitigates lipopolysaccharide-induced acute lung injury by suppression of oxidative stress and endoplasmic reticulum (ER) stress associated NF-kappaB signaling. ALI, CHOP, CRBN, eIF2alpha, ER, GRP78, HO-1, LDH, LPS, MPO, NF-kappaB, Nrf2, ROS
25  2019 Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells. EMT, ER stress, HLECs, TG, TM, TUDCA
26  2019 Enhanced endoplasmic reticulum and mitochondrial stress in abdominal aortic aneurysm. 7-KC, AAA, APCI, CHOP, CVDs, ER, HC, ROS, SEL1L, XBP1
27  2019 Gambogic Acid Shows Anti-Proliferative Effects on Non-Small Cell Lung Cancer (NSCLC) Cells by Activating Reactive Oxygen Species (ROS)-Induced Endoplasmic Reticulum (ER) Stress-Mediated Apoptosis. AG, ER, GRP, IRE, MTT, NSCLC, ROS
28  2019 Hydrogen alleviated organ injury and dysfunction in sepsis: The role of cross-talk between autophagy and endoplasmic reticulum stress: Experimental research. 4-PBA, BAL, CHOP, CLP, eIF2alpha, ELISA, HMGB, IL, IRE1alpha, MPO, NF kappa B, PERK, PINK1, TNF-alpha
29  2019 Janus Kinase 1 Is Required for Transcriptional Reprograming of Murine Astrocytes in Response to Endoplasmic Reticulum Stress. CCL2, ER, GADD, IL-6, JAK, OSM, PERK, TNF-alpha, TRIB, UPR
30  2019 Loss of X-box binding protein 1 in Muller cells augments retinal inflammation in a mouse model of diabetes. eIF, ER, JNK, MG, VEGF, XBP1
31  2019 Nuclear factor-erythroid 2-related factor 3 (NRF3) is low expressed in colorectal cancer and its down-regulation promotes colorectal cancer malignance through activating EGFR and p38/MAPK. CHOP, CRC, EGFR, NRF3, pEGFR Tyr845
32  2019 Schizandrin B Mitigates Rifampicin-Induced Liver Injury by Inhibiting Endoplasmic Reticulum Stress. ARMET, CHOP, ER, GRP78, IRE1, PERK, RFP, XBP1
33  2019 Silica nanoparticles induce caspase-dependent apoptosis through reactive oxygen species-activated endoplasmic reticulum stress pathway in neuronal cells. CHOP, ER, GRP, NAC, ROS, SiNPs
34  2018 Activating Transcription Factor 3 as a Novel Regulator of Chemotherapy Response in Breast Cancer. ---
35  2018 Activating transcription factor 3 in cardiovascular diseases: a potential therapeutic target. CREB, CVDs
36  2018 BCR-ABL tyrosine kinase inhibition induces metabolic vulnerability by preventing the integrated stress response in K562 cells. CML, eIF, ISR, PERK
37  2018 Development of cyclic AMP receptor protein-based artificial transcription factor for intensifying gene expression. 3-HP, 3-HPA, CRP, LacI, RNAPs
38  2018 Dexamethasone-induced production of reactive oxygen species promotes apoptosis via endoplasmic reticulum stress and autophagy in MC3T3-E1 cells. CDK, CHOP, DEX, ER, GCs, LC, ROS
39  2018 Effect of sodium 4-phenylbutyrate on Clenbuterol-mediated muscle growth. ISR, PBA, XBP1
40  2018 Elevated Cyclic AMP Inhibits Mycobacterium tuberculosis-Stimulated T-cell IFN-gamma Secretion Through Type I Protein Kinase A. cAMP, CREB, LTBI, PBMC
41  2018 Endogenous Purification of NR4A2 (Nurr1) Identified Poly(ADP-Ribose) Polymerase 1 as a Prime Coregulator in Human Adrenocortical H295R Cells. ---
42  2018 Endoplasmic reticulum stress and unfolded protein response profile in quadriceps of sarcopenic patients with respiratory diseases. COPD, ER, FFMI, IRE, LC, PERK, UPR, VL
43  2018 Hepatic alcohol dehydrogenase deficiency induces pancreatic injury in chronic ethanol feeding model of deer mice. ACP, eIF, ER, FAEEs, GRP, UPR
44  2018 Hepatic regulation of VLDL receptor by PPARbeta/delta and FGF21 modulates non-alcoholic fatty liver disease. eIF2alpha, ER, FGF21, PPAR, VLDLR
45  2018 JNK and ATF4 as two important platforms for tumor necrosis factor-alpha-stimulated shedding of receptor for advanced glycation end products. sRAGE, UPR
46  2018 miR-103/107 promote ER stress-mediated apoptosis via targeting the Wnt3a/beta-catenin/ATF6 pathway in preadipocytes. BCL2, ER, Wnt3a
47  2018 Placental Adaptation to Early-Onset Hypoxic Pregnancy and Mitochondria-Targeted Antioxidant Therapy in a Rodent Model. UPR
48  2018 Preemptive Activation of the Integrated Stress Response Protects Mice From Diet-Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction. eIF2alpha, FGF21, HFD, HS, IR, ISR, SH, WAT
49  2018 Proviral insertion in murine lymphomas 2 promotes stomach cancer progression by regulating apoptosis via reactive oxygen species-triggered endoplasmic reticulum stress. CHOP, ER, JNK, PIM2, ROS, XBP1
50  2018 Puromycin aminonucleoside triggers apoptosis in podocytes by inducing endoplasmic reticulum stress. BiP, ER, FACS, PAN, TUNEL
51  2018 Quercetin induced apoptosis of human oral cancer SAS cells through mitochondria and endoplasmic reticulum mediated signaling pathways. Bcl, DeltaPsim, PI
52  2018 The Crosstalk of Endoplasmic Reticulum (ER) Stress Pathways with NF-kappaB: Complex Mechanisms Relevant for Cancer, Inflammation and Infection. CEBP, ER, IkappaB, NF-kappaB, TFs, UPR, XBP
53  2018 The p38-activated ER stress-ATF6alpha axis mediates cellular senescence. BRCA, ER, UPR
54  2018 Understanding of the functional role(s) of the Activating Transcription Factor 4(ATF4) in HIV regulation and production. ATF4, UPR
55  2017 Activating transcription factor 3 regulates chemokine expression in contracting C2C12 myotubes and in mouse skeletal muscle after eccentric exercise. ATF3-KO, CCL, cd68, CXCL, IL
56  2017 ATF2 translation is induced under chemotherapeutic drug-mediated cellular stress via an IRES-dependent mechanism in human hepatic cancer Bel7402 cells. ADR, IRES, nt, PTX, UTR
57  2017 Biobehavioral modulation of the exosome transcriptome in ovarian carcinoma. CREB, EMT
58  2017 DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation. ---
59  2017 Endoplasmic reticulum chaperone GRP78 regulates macrophage function and insulin resistance in diet-induced obesity. UPR
60  2017 Maternal high-fat diet induces metabolic stress response disorders in offspring hypothalamus. BiP, DRP, ER, Erdj, GRP, MC4R, NPY, NPY1R, PBA, PINK, POMC, UPR
61  2017 MIF-2/D-DT enhances proximal tubular cell regeneration through SLPI- and ATF4-dependent mechanisms. eIF, ISR, MIF, MPT, SLPI, WT
62  2017 Neuroinflammation alters cellular proteostasis by producing endoplasmic reticulum stress, autophagy activation and disrupting ERAD activation. ER, ERAD, GSK, IRE, LPS, mTOR, UPR, XBP
63  2017 p32 is Required for Appropriate Interleukin-6 Production Upon LPS Stimulation and Protects Mice from Endotoxin Shock. IL-6, LPS, MEFs
64  2017 Periostin has a protective role in melatonin‑induced cell apoptosis by inhibiting the eIF2alpha‑ATF4 pathway in human osteoblasts. CHOP, eIF2alpha, ERS, GRP, POSTN, XBP1
65  2017 Regulation of Cancer Cell Responsiveness to Ionizing Radiation Treatment by Cyclic AMP Response Element Binding Nuclear Transcription Factor. CREB, IR
66  2017 Selenium Protects against Lead-induced Apoptosis via Endoplasmic Reticulum Stress in Chicken Kidneys. Bcl-2, ER, GRP, iNOS, IRE, mRNA, NO, Se
67  2017 Tanshinone IIA increases protein expression levels of PERK, ATF6, IRE1alpha, CHOP, caspase‑3 and caspase‑12 in pancreatic cancer BxPC‑3 cell‑derived xenograft tumors. CHOP, eIF, ER, IRE, PERK, Tan
68  2017 Targeted silencing of SOX2 by an artificial transcription factor showed antitumor effect in lung and esophageal squamous cell carcinoma. SCC
69  2017 The endoplasmic reticulum stress/autophagy pathway is involved in cholesterol-induced pancreatic beta-cell injury. 4-PBA, CHOP, eIF, ER, GRP, LC3
70  2016 Activating transcription factor 3 attenuates chemokine and cytokine expression in mouse skeletal muscle after exercise and facilitates molecular adaptation to endurance training. ATF3-KO, CCL, CD, CXCL, IL
71  2016 ATF3, a new player in DLBCL cell survival. DLBCL
72  2016 ATF7 ablation prevents diet-induced obesity and insulin resistance. ---
73  2016 CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas. ABC, AP-1, CARMA1, DLBCL, GC, MyD88, NF-kappaB
74  2016 Cisplatin-induced regulation of signal transduction pathways and transcription factors in p53-mutated subclone variants of hepatoma cells: Potential application for therapeutic targeting. Bcl, gamma-GCSh, GRP
75  2016 Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction. 11-epi-SA, C/EBP, ER, IRE1alpha, PKR, Sal
76  2016 Endoplasmic reticulum stress and dysregulation of calcium homeostasis mediate Cu-induced alteration in hepatic lipid metabolism of javelin goby Synechogobius hasta. 2-APB, 4-PBA, CRT, ER, GRP78, IRE, PERK, SREBP-1c
77  2016 Heme-Regulated eIF2alpha Kinase Modulates Hepatic FGF21 and Is Activated by PPARbeta/delta Deficiency. eIF2alpha, FGF21, PPAR, siRNA
78  2016 Induction of Endoplasmic Reticulum Stress via Reactive Oxygen Species Mediated by Luteolin in Melanoma Cells. CHOP, ER, ROS
79  2016 Novel mechanism of enhancing IRE1alpha-XBP1 signalling via the PERK-ATF4 pathway. ER, IRE1alpha, PKR, XBP1
80  2016 Protein Delivery of an Artificial Transcription Factor Restores Widespread Ube3a Expression in an Angelman Syndrome Mouse Brain. AS
81  2016 Temporal regulation of extracellular signal-regulated kinase 1/2 phosphorylation, heat shock protein 70 and activating transcription factor 3 during prostaglandin F-induced luteal regression in pseudopregnant rats following heat stress. ERK, HSP, MAPK, NHS, PGF, PK
82  2016 TMPRSS4 induces invasion and proliferation of prostate cancer cells through induction of Slug and cyclin D1. AP-1, EMT
83  2016 Tumor Necrosis Factor-alpha Attenuates the Osteogenic Differentiation Capacity of Periodontal Ligament Stem Cells by Activating PERK Signaling. C/EBP, ER, GRP, PBA, PDLSCs, PKR, TNF
84  2015 A Novel Microtubule-Disrupting Agent Induces Endoplasmic Reticular Stress-Mediated Cell Death in Human Hepatocellular Carcinoma Cells. DeltaPsim, TCD
85  2015 Activating transcription factor 3--an endogenous inhibitor of myocardial ischemia-reperfusion injury (Review). MIRI
86  2015 Activation of sphingosine kinase 2 by endoplasmic reticulum stress ameliorates hepatic steatosis and insulin resistance in mice. ER, FA, HFD, S1P, SphK, UPR
87  2015 Activation of the unfolded protein response in aged human lenses. BiP, ER, Ero1-L, HLEC, IRE, ROS, UPR
88  2015 All-Trans Retinoic Acid Induces TGF-beta2 in Intestinal Epithelial Cells via RhoA- and p38alpha MAPK-Mediated Activation of the Transcription Factor ATF2. ATRA, IECs, NEC, ROCK1, RT-qPCR, TGF
89  2015 Cytomorphology and immunohistochemistry of a recurrent clear cell odontogenic carcinoma with molecular analysis: A case report with review of literature. CCOC, EWSR1, FISH
90  2015 Endoplasmic reticulum stress pathway mediates isoflurane-induced neuroapoptosis and cognitive impairments in aged rats. CHOP, eIF, ERS, POCD
91  2015 Endoplasmic Reticulum Stress-Related Genes in Yellow Catfish Pelteobagrus fulvidraco: Molecular Characterization, Tissue Expression, and Expression Responses to Dietary Copper Deficiency and Excess. CRT, ER, GRP78, ire, PERK
92  2015 Erythropoietin delivered via intra-arterial infusion reduces endoplasmic reticulum stress in brain microvessels of rats following cerebral ischemia and reperfusion. CHOP, EPO, ER, MCA, MCAI, SI
93  2015 Glatiramer acetate treatment negatively regulates type I interferon signaling. GA, IFN, IFNAR1, IRF3, MS, MyD88, WT
94  2015 Improved n-butanol tolerance in Escherichia coli by controlling membrane related functions. ---
95  2015 Increased Endoplasmic Reticulum Stress in Human Glaucomatous Trabecular Meshwork Cells and Tissues. CHOP, eIF-2alpha, ER, ERO-1alpha, IOP, POAG, TM
96  2015 Inhibition of cyclic AMP response element-directed transcription by decoy oligonucleotides enhances tumor-specific radiosensitivity. CREB
97  2015 Methyl-deficient diet promotes colitis and SIRT1-mediated endoplasmic reticulum stress. BiP, DSS, ER, HSF1, HSP, MDD, SIRT1, TO, UPR
98  2015 microRNA-26a modulates inflammatory response induced by toll-like receptor 4 stimulation in microglia. ATF2, IL-6, JNK, LPS, TLR4, TNF-alpha
99  2015 Myxoma virus attenuates expression of activating transcription factor 4 (ATF4) which has implications for the treatment of proteasome inhibitor-resistant multiple myeloma. ATF4
100  2015 Roles of oxidative stress and the ERK1/2, PTEN and p70S6K signaling pathways in arsenite-induced autophagy. DNMT1, mTOR, OGG1, p-p70S6K, p70S6K, PI3K, PTEN