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■ Abbreviation / Long Form : Bach1 / BTB and CNC homology 1

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Total Number of Papers: 79
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Abbreviation:   Bach1  (>> Co-occurring Abbreviation)
Long Form:   BTB and CNC homology 1
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No. Year Title Co-occurring Abbreviation
2022 BACH1-Hemoxygenase-1 axis regulates cellular energetics and survival following sepsis. CLP
2022 Enhancing the HSV-1-mediated antitumor immune response by suppressing Bach1. HSV-1, ISGs, T-VEC
2022 Ferroptosis: regulation by competition between NRF2 and BACH1 and propagation of the death signal. FSP1, Nrf2
2022 Genetic BACH1 deficiency alters mitochondrial function and increases NLRP3 inflammasome activation in mouse macrophages. LPS, mtROS
2022 Inhibiting BTB domain and CNC homolog 1 (Bach1) as an alternative to increase Nrf2 activation in chronic diseases. Nrf2, sMaf
2022 Juvenile Plasma Factors Improve Organ Function and Survival following Injury by Promoting Antioxidant Response. Nrf2
2022 Nonalcoholic steatohepatitis and mechanisms by which it is ameliorated by activation of the CNC-bZIP transcription factor Nrf2. ATF3, beta-TrCP, ER, Keap1, NASH, NF-kappaB, Nrf2, TGF-beta
2022 Overexpression of BACH1 mediated by IGF2 facilitates hepatocellular carcinoma growth and metastasis via IGF1R and PTK2. ChIP, HCC, IGF1R, IGF2, IHC, OS, PTK2
2022 Protective effect of tin chloride on rhabdomyolysis-induced acute kidney injury in rats. BUN, CREA, GLY, HO-1, RM-AKI
10  2022 Role and Potential Mechanism of Heme Oxygenase-1 in Intestinal Ischemia-Reperfusion Injury. CO, HO, IR, NF-kappaB, Nrf2
11  2022 The SETD8/ELK1/bach1 complex regulates hyperglycaemia-mediated EndMT in diabetic nephropathy. DN, EndMT, HGECs, SETD8
12  2022 Uncovering BTB and CNC Homology1 (BACH1) as a Novel Cancer Therapeutic Target. TMB
13  2021 A heme-regulatable chemodynamic nanodrug harnessing transcription factor Bach1 against lung cancer metastasis. CDT, Fc, HO-1, NSCLC, TinPPIX
14  2021 An Analysis of the Multifaceted Roles of Heme in the Pathogenesis of Cancer and Related Diseases. CBS, NOS, OXPHOS, PGRMC1, sGC
15  2021 BACH1 promotes the progression of esophageal squamous cell carcinoma by inducing the epithelial-mesenchymal transition and angiogenesis. ChIP-qPCR, DFS, EMT, ESCC, IF, IHC, OS, VEGF-C
16  2021 BTB and CNC homology 1 (Bach1) induces lung cancer stem cell phenotypes by stimulating CD44 expression. CSCs, EdU, HE, MAPK, RT-qPCR
17  2021 Chronic intermittent hypoxia promoted lung cancer stem cell-like properties via enhancing Bach1 expression. CIH, CSCs, mtROS, OSA
18  2021 Heme Oxygenase-1 Contributes to Both the Engulfment and the Anti-Inflammatory Program of Macrophages during Efferocytosis. eRBCs, HO-1, MAP
19  2021 Long non-coding RNA NEAT1 absorbs let-7 g-5p to induce epithelial-mesenchymal transition of colon cancer cells through upregulating BACH1. lncRNAs, NEAT1
20  2021 MicroRNA-532-5p upregulation protects neurological deficits after ischemic stroke through inhibition of BTB and CNC homology 1. IS, MCAO, miR
21  2021 MicroRNA-98-5p inhibits human mesangial cell proliferation and TNF-alpha and IL-6 secretion by targeting BTB and CNC homology 1. CCK-8, LN, miR, RT-qPCR
22  2021 Mitochondrial Metabolism Targeted Nanoplatform for Efficient Triple-Negative Breast Cancer Combination Therapy. ATP, AVO, ETC, ZIF-90
23  2021 PDLIM2 repression by ROS in alveolar macrophages promotes lung tumorigenesis. AMs, PDLIM2
24  2021 Pharmacological Targeting of Heme Oxygenase-1 in Osteoarthritis. HO-1, NF-E2, OA, ROS, Sp1
25  2021 Regulatory mechanisms of heme regulatory protein BACH1: a potential therapeutic target for cancer. bZIP, MAF
26  2021 Role of the Transcription Factor BTB and CNC Homology 1 in a Rat Model of Acute Liver Injury Induced by Experimental Endotoxemia. HO-1, LPS
27  2021 The transcription factor BACH1 at the crossroads of cancer biology: From epithelial-mesenchymal transition to ferroptosis. EMT
28  2020 AMPK Enhances Transcription of Selected Nrf2 Target Genes via Negative Regulation of Bach1. AMPK, ARE, Nrf2, SFN
29  2020 Bach1 Inhibition Suppresses Osteoclastogenesis via Reduction of the Signaling via Reactive Oxygen Species by Reinforced Antioxidation. Nrf2, RANKL, ROS
30  2020 BACH1 Promotes Pancreatic Cancer Metastasis by Repressing Epithelial Genes and Enhancing Epithelial-Mesenchymal Transition. PDAC
31  2020 BTB and CNC homology 1 inhibition ameliorates fibrosis and inflammation via blocking ERK pathway in pulmonary fibrosis. alpha-SMA, BALF, COL1A1, FN1, IL-6, IPF, JNK, MLFs, PF
32  2020 Circ_0123996 promotes cell proliferation and fibrosisin mouse mesangial cells through sponging miR-149-5p and inducing Bach1 expression. circRNAs, DN, HG, MMCs, T2D
33  2020 Downregulation of BACH1 Protects AGAINST Cerebral Ischemia/Reperfusion Injury through the Functions of HO-1 and NQO1. 3-NT, HO-1, I/R, MCAO/R, MDA, N2a, NQO1, OGD/R, ROS, SOD
34  2020 Evaluation of antioxidant capacity and immunomodulatory effects of cottonseed meal protein hydrolysate and its derivative peptides for hepatocytes of blunt snout bream (Megalobrama amblycephala). CAT, CPH, Keap1, NOX2, Nrf2, T-SOD
35  2020 Evaluation of antioxidant capacity and immunomodulatory effects of yeast hydrolysates for hepatocytes of blunt snout bream (Megalobrama amblycephala). AST, CAT, GPx, Keap1, LDH, MDA, NOX2, Nrf2, SOD, UN, YH
36  2020 MALAT1 and BACH1 are prognostic biomarkers for triple-negative breast cancer. DFS, MALAT1, OS, TNBC
37  2020 Omega-3 fatty acids protect against acetaminophen-induced hepatic and renal toxicity in rats through HO-1-Nrf2-BACH1 pathway. IL, NF-B, Nrf2, TNF-alpha
38  2019 Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells. hESCs, PRC2, Usp7
39  2019 BTB and CNC homology 1 (Bach1) promotes human ovarian cancer cell metastasis by HMGA2-mediated epithelial-mesenchymal transition. EMT, EOC
40  2019 Downregulation of Bach1 protects osteoblasts against hydrogen peroxide-induced oxidative damage in vitro by enhancing the activation of Nrf2/ARE signaling. ARE, Nrf2, ROS
41  2019 Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. ETC, TNBC
42  2019 HMGA2 and Bach-1 cooperate to promote breast cancer cell malignancy. HMGA2
43  2019 Increased expression of heme oxygenase-1 suppresses airway branching morphogenesis in fetal mouse lungs exposed to inflammation. HO-1, IL-6, LPS, mRNA, WT
44  2019 SIRT6 protects retinal ganglion cells against hydrogen peroxide-induced apoptosis and oxidative stress by promoting Nrf2/ARE signaling via inhibition of Bach1. ARE, Nrf2, RGCs, ROS, SIRT6
45  2019 TLR4 activation alters labile heme levels to regulate BACH1 and heme oxygenase-1 expression in macrophages. CO, HMDMs, HO, LPS, mBMDMs, TLR
46  2018 Bach1: Function, Regulation, and Involvement in Disease. ---
47  2018 Carnosic acid attenuates cartilage degeneration through induction of heme oxygenase-1 in human articular chondrocytes. CA, HO-1, OA
48  2018 Functional role of BTB and CNC Homology 1 gene in pancreatic cancer and its association with survival in patients treated with gemcitabine. PDAC
49  2018 Heme oxygenase-1 prevents murine intestinal inflammation. HOs
50  2018 MicroRNA-98-5p ameliorates oxygen-glucose deprivation/reoxygenation (OGD/R)-induced neuronal injury by inhibiting Bach1 and promoting Nrf2/ARE signaling. ARE, miR-98-5p, miRNA, Nrf2, OGD/R, ROS
51  2018 Protective Effects of Astragaloside IV Combined with Budesonide in Bronchitis in Rats by Regulation of Nrf2/Keap1 Pathway. AG, Bax, BC, Bcl-2, BG, BM, CAT, CG, ECH, ELISA, GSH-Px, MDA, NF-E2, SD, SOD
52  2017 Dynamic changes in Bach1 expression in the kidney of rhabdomyolysis-associated acute kidney injury. HO-1, RM-AKI
53  2017 Erythropoietin rescues primary rat cortical neurons from pyroptosis and apoptosis via Erk1/2-Nrf2/Bach1 signal pathway. EPO, LDH, MDA, Nrf2, PI, SOD
54  2017 Genetic ablation of Bach1 gene enhances recovery from hyperoxic lung injury in newborn mice via transient upregulation of inflammatory genes. HO, IL, MCP
55  2017 Inhibition of monoamine oxidase-B by selegiline reduces cigarette smoke-induced oxidative stress and inflammation in airway epithelial cells. AECs, CAT, COPD, CSM, HO-1, MAO, NF-kappaB, NQO1, Nrf2, SOD
56  2017 MiR-155 enhances phagocytic activity of beta-thalassemia/HbE monocytes via targeting of BACH1. RBC
57  2017 The electrophilic character of quinones is essential for the suppression of Bach1. ARE, Keap1, Nrf2
58  2016 Bach1 Induces Endothelial Cell Apoptosis and Cell-Cycle Arrest through ROS Generation. ECs, HMVECs, NAC, ROS
59  2016 BACH1 silencing by siRNA inhibits migration of HT-29 colon cancer cells through reduction of metastasis-related genes. qRT-PCR
60  2016 Genomewide approaches for BACH1 target genes in mouse embryonic fibroblasts showed BACH1-Pparg pathway in adipogenesis. ChIP-sequence, iMEFs, MEFs, WT
61  2016 MiR-196a regulates heme oxygenase-1 by silencing Bach1 in the neonatal mouse lung. HO-1, miRNAs
62  2016 RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice. Nrf2, RANKL, ROS
63  2016 Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling. ARE, CRM1, JNK, Keap1, Nrf2, ROS, TCBQ
64  2016 The Ratio of Hmox1/Nrf2 mRNA Level in the Tumor Tissue Is a Predictor of Distant Metastasis in Colorectal Cancer. CRC, HMOX1, Keap1
65  2016 Transketolase counteracts oxidative stress to drive cancer development. Keap1, Nrf2, PPP, TKT
66  2015 Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1. HO-1, IL-1beta, LC3, OA, siRNA, SOD2
67  2015 Correlation of BACH1 and Hemoglobin E/Beta-Thalassemia Globin Expression. HbE
68  2015 Dual regulation of skin sensitizer-induced HMOX1 expression by Bach1 and Nrf2: Comparison to regulation of the AKR1C2-ARE element in the KeratinoSens cell line. AKR1C2, ARE, Nrf2
69  2014 Characterization of docosahexaenoic acid (DHA)-induced heme oxygenase-1 (HO-1) expression in human cancer cells: the importance of enhanced BTB and CNC homology 1 (Bach1) degradation. AREs, DHA, HO-1
70  2013 Activation of the Nrf2 pathway by inorganic arsenic in human hepatocytes and the role of transcriptional repressor Bach1. HO-1, NQO1, Nrf2
71  2013 Bach1 deficiency protects pancreatic beta-cells from oxidative stress injury. HO-1, WT
72  2013 BTB and CNC homolog 1 (Bach1) deficiency ameliorates TNBS colitis in mice: role of M2 macrophages and heme oxygenase-1. HO-1, TNBS
73  2013 Immunohistochemical study of the Nrf2 pathway in colorectal cancer: Nrf2 expression is closely correlated to Keap1 in the tumor and Bach1 in the normal tissue. CI, IHC, Keap1, PARK7
74  2012 Identification of a novel role of ESAT-6-dependent miR-155 induction during infection of macrophages with Mycobacterium tuberculosis. BMDMs, COX-2, HO-1, IL-6, Mtb
75  2011 Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency. HO-1, TUNEL
76  2011 The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. ---
77  2010 Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1. AML, HO, LPS, Nrf2, PHA
78  2010 Inhibition of Bach1 ameliorates indomethacin-induced intestinal injury in mice. HO-1
79  2010 Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential. HO, Nrf2, PI3K