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■略語／展開語 : CLR／clearance

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合計出現文献数:

256

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100 件 (発表年降順)100 件 (発表年昇順)全件

略語:	CLR ( >>共起略語 )
展開形:	clearance (代謝異物を腎臓が尿中に排出する機能の尺度) クリアランス, (体内異物の) 排除, 排出能, 浄化値, 清掃率

略語バリエーション

CLR (134)回

CLr (56)回

Clr (43)回

ClR (24)回

CL r (1)回

CL R (1)回

展開形バリエーション

clearance (256)回

clearances (3)回

ペア(略語／展開形)バリエーション

CLR / clearance (132)回

CLr / clearance (56)回

Clr / clearance (42)回

ClR / clearance (24)回

CLR / clearances (2)回

CL R / clearance (1)回

CL r / clearance (1)回

Clr / clearances (1)回

No.

発表年

題目

共起略語

2024

Can non-renal clearance and/or bioavailability of drugs be assessed reliably in renal impairment studies with oral drug administration?

CKD, CLNR, DRIS

2024

Determination of Vatiquinone Drug-Drug Interactions, as CYP450 Perpetrator and Victim, Using Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation.

AUC, PBPK

2024

Effects of Cimetidine and Dolutegravir on the Endogenous Drug-Drug Interaction Biomarkers for Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Protein 1 in Healthy Volunteers.

1-NMN, CLrR, DDI, m1A

2024

Loganin Ameliorates Acute Kidney Injury and Restores Tofacitinib Metabolism in Rats: Implications for Renal Protection and Drug Interaction.

AKI, CLCR, CLNR, CON, JAK, LGN

2024

Pharmacokinetic interactions of niclosamide in rats: Involvement of organic anion transporters 1 and 3 and organic cation transporter 2.

---

2024

Pharmacokinetics, Pharmacodynamics, and Safety of Single Dose HSK7653 Tablets in Chinese Subjects with Normal or Impaired Renal Function.

DPP-4, PDs, PKs

2024

Understanding adefovir pharmacokinetics as a component of a transporter phenotyping cocktail.

OAT1, PopPK

2023

An exploration on retro-construction of plasma drug concentration-time curves from corresponding urine excretion data and single-point plasma concentrations using a simplified and idealized method.

C-T, PK

2023

Dose adjustment not required for contezolid in patients with moderate hepatic impairment based on pharmacokinetic/pharmacodynamic analysis.

Ae0-48h, CFR, PK, PTA

2023

Impact of Pregnancy on the Pharmacokinetics and Metabolism of Nicotinamide in Humans.

AUC, M2PY, MNA, NAM

2023

Population Pharmacokinetic Analyses for Tebipenem after Oral Administration of Pro-Drug Tebipenem Pivoxil Hydrobromide.

AP, CLCR, PK, TBP-PI-HBr, cUTI

2023

Renal tubular transporter-mediated interactions between mirogabalin and cimetidine in rats.

PAH

2022

Coproporphyrin I as an Endogenous Biomarker to Detect Reduced OATP1B Activity and Shift in Elimination Route in Chronic Kidney Disease.

AUCR, CKD, CPI, OATP1B, PBPK, fup

2022

Developmental pharmacokinetics of indomethacin in preterm neonates: Severely decreased drug clearance in the first week of life.

2022

Effect of Chronic Kidney Disease on the Renal Secretion via Organic Anion Transporters 1/3: Implications for Physiologically-Based Pharmacokinetic Modeling and Dose Adjustment.

CKD, GFR

2022

Influence of Renal Function on Phosphoramide Mustard Exposure: A Nonlinear Mixed-Effects Analysis.

AUC, CrCl, PM

2022

Pharmacokinetics of Oral Tebipenem Pivoxil Hydrobromide in Subjects with Various Degrees of Renal Impairment.

AUC, CLCR, ESRD, HD, MDR, PK, TBP-PI-HBr

2022

Sulopenem: An Intravenous and Oral Penem for the Treatment of Urinary Tract Infections Due to Multidrug-Resistant Bacteria.

AUC, ESBL, MDR, MRSA, MSSA, NDA, PBP, TEAEs, UTIs, Vd

2021

Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system.

CKD, HUVEC, M6G, PBPK, PTEC, VPT-MPS

2021

Estimation of Ontogeny Functions for Renal Transporters Using a Combined Population Pharmacokinetic and Physiology-Based Pharmacokinetic Approach: Application to OAT1,3.

PBPK, PopPK