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■ Abbreviation / Long Form : CPT1A / carnitine palmitoyltransferase 1A

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Total Number of Papers: 186
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Abbreviation:   CPT1A  (>> Co-occurring Abbreviation)
Long Form:   carnitine palmitoyltransferase 1A
 Abbreviation Variation
 Long Form Variation
 Pair(Abbreviation/Long Form) Variation
No. Year Title Co-occurring Abbreviation
2022 2,3,5,4'-tetrahydroxy-stilbene-2-O-β-D-glucoside ameliorates NAFLD via attenuating hepatic steatosis through inhibiting mitochondrial dysfunction dependent on SIRT5. MCD, NAFLD, NEFA, RBP, ROS, SIRT5, SRSF2, TSG
2022 Apoptosis induction in human prostate cancer cells related to the fatty acid metabolism by wogonin-mediated regulation of the AKT-SREBP1-FASN signaling network. FASN, PCa, ROS, SREBP1
2022 Augmented CPT1A Expression Is Associated with Proliferation and Colony Formation during Barrett's Tumorigenesis. BE, GERD
2022 Ct-OATP1B3 promotes high-grade serous ovarian cancer metastasis by regulation of fatty acid beta-oxidation and oxidative phosphorylation. ATP, Ct-OATP1B3, FAO, HGSOC, IGF2BP2, OXPHOS, SLCO1B3
2022 Decrease of Intracellular Glutamine by STF-62247 Results in the Accumulation of Lipid Droplets in von Hippel-Lindau Deficient Cells. ccRCC, PLIN2, VHL
2022 Disturbance of Fatty Acid Metabolism Promoted Vascular Endothelial Cell Senescence via Acetyl-CoA-Induced Protein Acetylation Modification. acetyl-CoA, FAO, HUVECs, SCFAs
2022 Downregulation of CPT1A exerts a protective effect in dextran sulfate sodium-induced ulcerative colitis partially by inhibiting PPARα signaling pathway. DSS, PPARalpha, UC
2022 Enhanced T Cell Glucose Uptake Is Associated With Progression of Beta-Cell Function in Type 1 Diabetes. GLUT1
2022 Genotype-phenotype correlations in CPT1A deficiency detected by newborn screening in Pacific populations. EMS, NZ
10  2022 Gypenosides ameliorate high-fat diet-induced non-alcoholic steatohepatitis via farnesoid X receptor activation. AST, FASN, FBG, FINS, FXR, Gyps, HFD, KO, LDL-C, LPL, NAFLD, NASH, ND, OCA, SCD1, SHP, SREBP1, TC, TG, WT
11  2022 Hypoxic mesenchymal stem cell-derived extracellular vesicles ameliorate renal fibrosis after ischemia-reperfusion injure by restoring CPT1A mediated fatty acid oxidation. FAO, hPMSC, Hypo-EVs, I/R, ROS
12  2022 Immunofluorescence-Based Method to Assess Cancer Biomarker in the Hypoxic Region of the Tumor. PCa
13  2022 In Situ Analysis of mTORC1/C2 and Metabolism-Related Proteins in Pediatric Osteosarcoma. ATPB, FASN, G6PDH, GLS, LDHA, mTOR, p-mTOR, PFK, pS6
14  2022 Increased mitochondrial fission drives the reprogramming of fatty acid metabolism in hepatocellular carcinoma cells through suppression of Sirtuin 1. ACC1, ACOX1, ELOVL6, FASN, HCC, SIRT1, SREBP1
15  2022 Indole alkaloids of Alstonia scholaris (L.) R. Br. alleviated nonalcoholic fatty liver disease in mice fed with high-fat diet. ACOX1, AST, HDL, HFD, LDL, LXRalpha, NAFLD, PPAR, SCD1, SREBP-1C, TG
16  2022 Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis. FBS, HSCs, TGF-beta1
17  2022 L-theanine prevents progression of nonalcoholic hepatic steatosis by regulating hepatocyte lipid metabolic pathways via the CaMKKβ-AMPK signaling pathway. ALT, AMPK, AST, CaMKKbeta, HFD, LDL-C, NAFLD, NCD, OA, PPARalpha, SREBP-1c, TG
18  2022 Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer. FAO, HGSOC
19  2022 Optimization of the extract from flower of Citrus aurantium L. var. amara Engl. and its inhibition of lipid accumulation. FAS, MDA, PPARgamma, ROS, SOD, UCP2
20  2022 Overexpression CPT1A reduces lipid accumulation via PPARα/CD36 axis to suppress the cell proliferation in ccRCC. ccRCC, CD36, PPARalpha
21  2022 Roxadustat, a Hypoxia-Inducible Factor 1α Activator, Attenuates Both Long- and Short-Term Alcohol-Induced Alcoholic Liver Disease. ALD, CYP2E1, HIF-1alpha, PPARalpha, ROS, SOD1, SREBP-1c
22  2022 The daily caloric restriction and alternate-day fasting ameliorated lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1. ADF, CR, HG, NG, PES1, PPAR-alpha, T2DM
23  2022 Tubular Mitochondrial Dysfunction, Oxidative Stress, and Progression of Chronic Kidney Disease. AKI, CKD
24  2022 Withaferin A Inhibits Fatty Acid Synthesis in Rat Mammary Tumors. ACC1, ACLY, FASN, SREBP1
25  2022 Zinc Oxide Nanoparticles and Synthesized Pyrazolopyrimidine Alleviate Diabetic Effects in Rats Induced by Type II Diabetes. AST, DM, HDL-C, LDL-C, SOD, TC, TG, VLDL-C, ZnO NPs
26  2022 [Clinical features and genetic variants of a case with carnitine palmitoyltransferase 1A deficiency]. ---
27  2021 Activation of the Peroxisome Proliferator-Activated Receptors (PPAR-alpha/gamma) and the Fatty Acid Metabolizing Enzyme Protein CPT1A by Camel Milk Treatment Counteracts the High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease. CM, FABP1, HFD-C, IR, NAFLD, PPAR-alpha
28  2021 Association of CPT1A gene polymorphism with the risk of gestational diabetes mellitus: a case-control study. GDM, IR, SNPs
29  2021 Association of the CPT1A p.P479L Metabolic Gene Variant With Childhood Respiratory and Other Infectious Illness in Nunavut. LRTI
30  2021 Bioactive flavonoids and stilbenes from the leaf of Morus alba var. multicaulis. ACC1, AMPKalpha, FAS, SCD1, TG
31  2021 Carnitine palmitoyl transferase 1A is a novel diagnostic and predictive biomarker for breast cancer. ROC
32  2021 Carnitine palmitoyltransferase 1A is essential for decidualization in mice. siCPT1A
33  2021 CPT1A and fatty acid β-oxidation are essential for tumor cell growth and survival in hormone receptor-positive breast cancer. FAO
34  2021 CUN-BAE Index as a Screening Tool to Identify Increased Metabolic Risk in Apparently Healthy Normal-Weight Adults and Those with Obesity. CUN-BAE, FASN, NW, OWOB, PBMCs, SREBP-1c
35  2021 Downregulation of fatty acid oxidation by involvement of HIF-1alpha and PPARgamma in human gastric adenocarcinoma and related clinical significance. FAO, GA, HIF-1alpha, MCAD and LCAD, PPARgamma
36  2021 Echinacoside improves diabetic liver injury by regulating the AMPK/SIRT1 signaling pathway in db/db mice. ECH, FBG, PGC-1alpha, PPARalpha
37  2021 Elucidation of the mechanism of NEFA-induced PERK-eIF2alpha signaling pathway regulation of lipid metabolism in bovine hepatocytes. apoB, CHOP, eIF2alpha, ERS, FASN, GRP78, LDLR, NEB, NEFA, PERK, PPARalpha, SREBP-1c, TG, VLDL
38  2021 Epigenetic Silencing of miR-33b Promotes Peritoneal Metastases of Ovarian Cancer by Modulating the TAK1/FASN/CPT1A/NF-kappaB Axis. FASN, HGSOC, OCM, TAK1, TME
39  2021 Ethyl 2-[2,3,4-Trimethoxy-6-(1-Octanoyl)Phenyl] Acetate (TMPA) Ameliorates Lipid Accumulation by Disturbing the Combination of LKB1 with Nur77 and Activating the AMPK Pathway in HepG2 Cells and Mice Primary Hepatocytes. AMPKalpha, FFAs, HMGCR, TMPA
40  2021 Fatty acid β-oxidation promotes breast cancer stemness and metastasis via the miRNA-328-3p-CPT1A pathway. miRNA
41  2021 Hepatic CPT1A Facilitates Liver-Adipose Cross-Talk via Induction of FGF21 in Mice. FGF21, HFD, PPARalpha, WT
42  2021 Hepatic CPT1A Facilitates Liver-Adipose Cross-Talk via Induction of FGF21 in Mice. FGF21, HFD, PPARalpha, WT
43  2021 iRGD-modified exosomes effectively deliver CPT1A siRNA to colon cancer cells, reversing oxaliplatin resistance by regulating fatty acid oxidation. FAO
44  2021 Kidney plays an important role in ketogenesis induced by risperidone and voluntary exercise in juvenile female rats. betaHB, HMGCS2
45  2021 Metabolic flexibility maintains proliferation and migration of FGFR signaling-deficient lymphatic endothelial cells. FAO, FGFR, LECs
46  2021 Novel mutation in carnitine palmitoyltransferase 1A detected through newborn screening for a presymptomatic case in China: a case report. FAO
47  2021 Osthole alleviates pulmonary vascular remodeling by modulating microRNA-22-3p mediated lipid metabolic reprogramming. cGMP, FAS, HDL-C, HK2, IDH3alpha, IR, ND1, PAH, PDE5, PLA2, TC, TG
48  2021 Overexpression of carnitine palmitoyltransferase 1A promotes mitochondrial fusion and differentiation of glioblastoma stem cells. GBM, GSCs, NSTCs
49  2021 P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid beta-Oxidation through AMPK and PGC-1alpha Induction in High-Fat Diet-Fed Mice. ACC, ALT, AMPK, AST, ATGL, FAO, FAS, HFD, NAFLD, PGC-1alpha, SCD1
50  2021 Photoaffinity-Based Chemical Proteomics Reveals 7-Oxocallitrisic Acid Targets CPT1A to Trigger Lipogenesis Inhibition. 7-OCA
51  2021 Poly-ion complex micelles effectively deliver CoA-conjugated CPT1A inhibitors to modulate lipid metabolism in brain cells. FAO, PIC
52  2021 Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis. CKD, CPT1A-KI, FAN, FAO, TECs
53  2021 Rosmarinic Acid Exhibits a Lipid-Lowering Effect by Modulating the Expression of Reverse Cholesterol Transporters and Lipid Metabolism in High-Fat Diet-Fed Mice. ABCG5, AMPK, CYP7A1, HFD, LDLR, RCT, SR-B1
54  2021 Silibinin improves nonalcoholic fatty liver by regulating the expression of miR‑122: An invitro and invivo study. ACC, FAS, miR
55  2021 Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis. FAO, HCC, HFD, SOAT1
56  2021 Three Novel and One Potential Hotspot CPT1A Variants in Chinese Patients With Carnitine Palmitoyltransferase 1A Deficiency. NBS
57  2021 [Analysis of a child with carnitine palmitoyl transferase 1A deficiency due to variant of CPT1A gene]. NGS
58  2021 β-elemene blocks lipid-induced inflammatory pathways via PPARβ activation in heart failure. EF, FS, HF, IkappaBalpha, IL-6, LAD, NF-kappaB, OGD/R, PPARbeta, SIRT3
59  2020 A patient with atypical presentation of chronic hepatosteatosis harboring a novel variant in the CPT1A gene. ---
60  2020 A translation repressor, 4E-BP1, regulates the triglyceride level in rat liver during protein deprivation. TG
61  2020 Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells. FAO, PD-MSCs
62  2020 Branched-Chain Fatty Acids as Mediators of the Activation of Hepatic Peroxisome Proliferator-Activated Receptor Alpha by a Fungal Lipid Extract. BCFAs, CHLE, CYP4A1, IPA, MHD, MTA, MTriA, PPARalpha, SLC22A5
63  2020 Carbohydrate and fat intake associated with risk of metabolic diseases through epigenetics of CPT1A. CHO, FHS, GOLDN
64  2020 Carbohydrate response element-binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy. ACC, ACOX1, ChREBP, DN, FASN, HG, mTORC1, PPARalpha, TXNIP
65  2020 Carnitine palmitoyltransferase 1 A expression profile in canine mammary tumors. CMTs, qRT-PCR
66  2020 Cationic Polymer Nanoparticles-Mediated Delivery of miR-124 Impairs Tumorigenicity of Prostate Cancer Cells. miR-124, miRNAs
67  2020 Effects of Breastfeeding and Formula Feeding on the Expression Level of FTO, CPT1A and PPAR-α Genes in Healthy Infants. FTO, PBMC, PPAR-alpha, RT-PCR
68  2020 Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet. ---
69  2020 Ginsenoside Rg1 Regulates Liver Lipid Factor Metabolism in NAFLD Model Rats. CPT2, CYP7A, GLU, IL-1, INS, NAFLD, PPAR-alpha, SD, SREBP-1C, TC, TG, TNF-alpha
70  2020 Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy. FAO, GBM, KD
71  2020 Growth hormone ameliorates high glucose-induced steatosis on in vitro cultured human HepG2 hepatocytes by inhibiting de novo lipogenesis via ChREBP and FAS suppression. ChREBP, FAS, GH, IGF-1, PPAR-alpha, SREBP-1c
72  2020 Inhibition of carnitine palmitoyl transferase 1A-induced fatty acid oxidation suppresses cell progression in gastric cancer. FAO, GC
73  2020 Inhibition of Carnitine Palmitoyltransferase 1A Aggravates Fatty Liver Graft Injury via Promoting Mitochondrial Permeability Transition. IRI, MPT
74  2020 Lipid in Renal Carcinoma: Queen Bee to Target? ccRCC, FA, FAO, HIFs
75  2020 LRRK2 Regulates CPT1A to Promote beta-Oxidation in HepG2 Cells. AMPK, LRRK2, NAFLD, PA, PPARalpha, TNF-alpha
76  2020 Lysine-222 succinylation reduces lysosomal degradation of lactate dehydrogenase a and is increased in gastric cancer. Co-IP, GC, LDHA, PLA, SQSTM1
77  2020 Melatonin Alleviates Glucose and Lipid Metabolism Disorders in Guinea Pigs Caused by Different Artificial Light Rhythms. AMPKalpha, HFD, p-AMPKalpha, PPARalpha
78  2020 Study on the protection of water extracts of Polygoni Multiflori Radix and Polygoni Multiflori Radix Praeparata against NAFLD and its mechanism. AST, BODIPY, ETO, HFD, HPLC, NAFLD, NEFA, PMR, PMRP, PMRPWE, PMRWE, ROS, TC, TG, TSG
79  2020 Targeting Fatty Acid Oxidation to Promote Anoikis and Inhibit Ovarian Cancer Progression. FAO, HGSOC
80  2020 The water extract of Sophorae tonkinensis Radix et Rhizoma alleviates non-alcoholic fatty liver disease and its mechanism. ALT/AST, ETO, HPLC, MCD, MDA, MPO, MT, NAFLD, NEFA, OMT, STR, TC, TG
81  2020 Withania somnifera root extract inhibits fatty acid synthesis in prostate cancer cells. ACC1, ACLY, FASN
82  2019 A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of BRAF-mutated Melanoma to MAPK Inhibitors. FAO, MAPKi
83  2019 Anti-Obesity Effects of Lactobacillus fermentum CQPC05 Isolated from Sichuan Pickle in High-Fat Diet-Induced Obese Mice through PPAR-alpha Signaling Pathway. AST, HDL-C, LDL-C, LPL, PPAR-alpha, PPARgamma, TC, TG
84  2019 CPT1A plays a key role in the development and treatment of multiple sclerosis and experimental autoimmune encephalomyelitis. EAE, HFD, MS, ND
85  2019 Effect of divergence in residual feed intake on expression of lipid metabolism-related genes in the liver of meat-type ducks1. ACC, ACOX1, ADFI, FAS, FCR, FOXO1, HRFI, LRFI, PPARgamma, RFI, SIRT1, SREBP-1c
86  2019 Fibroblast growth factor 21 protects against lipotoxicity-induced pancreatic beta-cell dysfunction via regulation of AMPK signaling and lipid metabolism. FA, FGF21, GSIS, HFD, HOMA-IR, KO, PA, PPARs
87  2019 Gut microbiota signatures and lipids metabolism profiles by exposure to polyene phosphatidylcholine. CD36, FASN, FATP5, FFA, L-FABP, LPS, PPC, TMAO
88  2019 Inhibition Effect of Triglyceride Accumulation by Large Yellow Croaker Roe DHA-PC in HepG2 Cells. DHA, DHA-PC, FAS, OA, PLs, PPARalpha
89  2019 Leptin promotes fatty acid oxidation and OXPHOS via the c-Myc/PGC-1 pathway in cancer cells. ND1, OXPHOS, PGC-1
90  2019 Liver-specific deletion of IGF2 mRNA binding protein-2/IMP2 reduces hepatic fatty acid oxidation and increases hepatic triglyceride accumulation. HFD, PPARalpha
91  2019 Long non‑coding RNA nuclear paraspeckle assembly transcript 1 interacts with microRNA‑107 to modulate breast cancer growth and metastasis by targeting carnitine palmitoyltransferase‑1. BC, NEAT1
92  2019 Low abundance of mitofusin 2 in dairy cows with moderate fatty liver is associated with alterations in hepatic lipid metabolism. BHB, DGAT1, FASN, Mfn2, NEFA, PPARalpha, SREBP-1c
93  2019 PGC1alpha/CEBPB/CPT1A axis promotes radiation resistance of nasopharyngeal carcinoma through activating fatty acid oxidation. CEBPB, FAO, NPC
94  2019 Potential role of ALDH3A2 on the lipid and glucose metabolism regulated by (-)-hydroxycitric acid in chicken embryos. ALDH3A2, PEPCK, PGC-1alpha, PPARalpha
95  2019 Protein and gene expression of relevant enzymes and nuclear receptor of hepatic lipid metabolism in grazing dairy cattle during the transition period. ACOX1, DGAT1, PPAR-alpha
96  2019 Tissue-based metabolomics reveals potential biomarkers for cervical carcinoma and HPV infection. CIN, GAD1, GSK-3beta, HPV, NCs, PCR, PKM2, SCC
97  2019 Use of Glucose, Glutamine and Fatty Acids for Trophoblast Respiration in Lean, Obese and Gestational Diabetic Women. ---
98  2018 Adaptations of hepatic lipid metabolism and mitochondria in dairy cows with mild fatty liver. ACC1, ACO, ATP, COXIV, FAS, NRF1, PA, PGC-1alpha, PPARalpha, SREBP-1c, VDAC1
99  2018 Adaptive evolution to a high purine and fat diet of carnivorans revealed by gut microbiomes and host genomes. LipF
100  2018 Analysis of genotype by methylation interactions through sparsity-inducing regularized regression. CpG, EWAS, GOLDN, GWAS, LASSO, SNPs