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[Related PubMed/MEDLINE]
Total Number of Papers: 76
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| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2022 |
Cullin 4A/protein arginine methyltransferase 5 (CUL4A/PRMT5) promotes cell malignant phenotypes and tumor growth in nasopharyngeal carcinoma. |
NPC, PRMT5 |
| 2 |
2022 |
How cells recognize and remove the perforated lysosome. |
--- |
| 3 |
2022 |
Lentivirus-mediated short hairpin RNA interference of CENPK inhibits growth of colorectal cancer cells with overexpression of Cullin 4A. |
CENPK, CRC, qPCR, shRNA |
| 4 |
2022 |
LINC01468 drives NAFLD-HCC progression through CUL4A-linked degradation of SHIP2. |
HCC, lncRNAs, m6A, NAFLD |
| 5 |
2022 |
The Nuclear Proteins TP73 and CUL4A Confer Resistance to Cytarabine by Induction of Translesion DNA Synthesis via Mono-ubiquitination of PCNA. |
AML, PCNA, siRNAs |
| 6 |
2022 |
Yeast beta-glucan Increases Etoposide Sensitivity in Lung Cancer Cell Line A549 by Suppressing Nuclear Factor Erythroid 2-Related Factor 2 via the Noncanonical Nuclear Factor Kappa B Pathway. |
EphA2, Keap1, MAPK, NF-kappaB, Nrf2, RelB, STAT3, WDR23 |
| 7 |
2021 |
CRL4ADTL degrades DNA-PKcs to modulate NHEJ repair and induce genomic instability and subsequent malignant transformation. |
DSBs, NHEJ |
| 8 |
2021 |
Exosome-mediated transfer of SNHG7 enhances docetaxel resistance in lung adenocarcinoma. |
ATG12, ATG5, HuR, lncRNA, LUAD, PI3K, PTEN, SNHG7 |
| 9 |
2021 |
LncRNA AIRN influences the proliferation and apoptosis of hepatocellular carcinoma cells by regulating STAT1 ubiquitination. |
HCC, LncRNAs |
| 10 |
2021 |
lncRNA NEAT1 facilitates the progression of colorectal cancer via the KDM5A/Cul4A and Wnt signaling pathway. |
CRC, lncRNAs, NEAT1 |
| 11 |
2021 |
OTUD1 Activates Caspase-Independent and Caspase-Dependent Apoptosis by Promoting AIF Nuclear Translocation and MCL1 Degradation. |
AIF, DCAF10, DDB1, Mcl-1, OTUD1 |
| 12 |
2021 |
Sp1 is a substrate of Keap1 and regulates the activity of CRL4AWDR23 ubiquitin ligase toward Nrf2. |
CRL4AWDR23, KD, Keap1, Nrf2, Sp1, WDR23 |
| 13 |
2021 |
The effect of cullin 4A on lung cancer cell chemosensitivity to paclitaxel through p33ING1b regulation. |
p33ING1b |
| 14 |
2020 |
CUL4A promotes proliferation and inhibits apoptosis of colon cancer cells via regulating Hippo pathway. |
CC, CCK-8, NC, qRT-PCR, siRNA, WB |
| 15 |
2020 |
CUL4A promotes the invasion of cervical cancer cells by regulating NF-kappaB signaling pathway. |
CC, mRNA, MTT, NF-kappaB, qRT-PCR, siRNA |
| 16 |
2020 |
CUL4A regulates endometrial cancer cell proliferation, invasion and migration by interacting with CSN6. |
CSN6, EC, hEECs, MMP, sh |
| 17 |
2020 |
Development of a Novel Oncolytic Adenovirus Expressing a Short-hairpin RNA Against Cullin 4A. |
OAd, shRNA |
| 18 |
2020 |
Effect of CUL4A on the metastatic potential of lung adenocarcinoma to the bone. |
ZEB1 |
| 19 |
2020 |
lncRNA SNHG11 Promotes Gastric Cancer Progression by Activating the Wnt/beta-Catenin Pathway and Oncogenic Autophagy. |
ATG12, CTNNB1, EMT, GC, lncRNAs, SNHG11 |
| 20 |
2020 |
The small molecule PSSM0332 disassociates the CRL4ADCAF8 E3 ligase complex to decrease the ubiquitination of NcoR1 and inhibit the inflammatory response in a mouse sepsis-induced myocardial dysfunction model. |
DDB1, HMGB1, RBX1, SIMD |
| 21 |
2020 |
Upregulated lncRNA DLX6-AS1 underpins hepatocellular carcinoma progression via the miR-513c/Cul4A/ANXA10 axis. |
ANXA10, DLX6-AS1, HCC, lncRNA |
| 22 |
2020 |
YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators. |
CDK1, Cul1, DDB1, m6A, Skp2, WEE1 |
| 23 |
2019 |
CENP-A Ubiquitylation Contributes to Maintaining the Chromosomal Location of the Centromere. |
CENP-A, COPS8 |
| 24 |
2019 |
CUL4A expression is associated with tumor stage and prognosis in nasopharyngeal carcinoma. |
HR, NPC, OS, PFS |
| 25 |
2019 |
Cul4A Modulates Invasion and Metastasis of Lung Cancer Through Regulation of ANXA10. |
ANXA10, NSCLC |
| 26 |
2019 |
Overexpression of Cullin4A correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma. |
DSS, ESCC |
| 27 |
2019 |
Reduced miR-363-3p expression in non-small cell lung cancer is associated with gemcitabine resistance via targeting of CUL4A. |
CCK-8, miRNAs, NSCLC, RT-qPCR |
| 28 |
2019 |
The cullin4A is up-regulated in chronic obstructive pulmonary disease patient and contributes to epithelial-mesenchymal transition in small airway epithelium. |
COPD, CSE, EMT, HSAEpiCs |
| 29 |
2018 |
A MicroRNA Derived from Adenovirus Virus-Associated RNAII Promotes Virus Infection via Posttranscriptional Gene Silencing. |
Ad, JNK, miRNAs, nt, PKR, VA-RNAI and -II |
| 30 |
2018 |
A Novel lncRNA, LINC00460, Affects Cell Proliferation and Apoptosis by Regulating KLF2 and CUL4A Expression in Colorectal Cancer. |
CRC, EZH2, KLF2, lncRNAs |
| 31 |
2018 |
High Expressions of CUL4A and TP53 in Colorectal Cancer Predict Poor Survival. |
DFS, EMT, IHC, OS, siRNA |
| 32 |
2018 |
Investigation of the role of cullin 4A overexpression in human liver cancer. |
--- |
| 33 |
2018 |
miR‑377 targets CUL4A and regulates metastatic capability in ovarian cancer. |
EMT, miRs |
| 34 |
2017 |
CUL4A enhances human trophoblast migration and is associated with pre-eclampsia. |
TIMP |
| 35 |
2017 |
CUL4A promotes cell invasion in gastric cancer by activating the NF-kappaB signaling pathway. |
GC, LPS, MMP, NF-kappaB |
| 36 |
2017 |
Cullin 4A is associated with epithelial to mesenchymal transition and poor prognosis in perihilar cholangiocarcinoma. |
EMT, IHC, OS, PFS, PHCC |
| 37 |
2017 |
Suppression of CUL4A attenuates TGF-β1-induced epithelial-to-mesenchymal transition in breast cancer cells. |
EMT, TGF-beta1, ZEB1 |
| 38 |
2016 |
Aiolos collaborates with Blimp-1 to regulate the survival of multiple myeloma cells. |
Blimp-1, MM |
| 39 |
2016 |
CUL4A functions as an oncogene in ovarian cancer and is directly regulated by miR-494. |
EMT |
| 40 |
2016 |
Cullin 4A (CUL4A), a direct target of miR-9 and miR-137, promotes gastric cancer proliferation and invasion by regulating the Hippo signaling pathway. |
EMT, GC, miRNAs |
| 41 |
2016 |
Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cells. |
TGF, TGFBI |
| 42 |
2015 |
Clinical significance of CUL4A in human prostate cancer. |
PCa |
| 43 |
2015 |
CUL4A expression in pediatric osteosarcoma tissues and its effect on cell growth in osteosarcoma cells. |
EMT, OS, qRT-PCR |
| 44 |
2015 |
DDB2 is involved in ubiquitination and degradation of PAQR3 and regulates tumorigenesis of gastric cancer cells. |
DDB2, EGF |
| 45 |
2015 |
Knockdown of Cul4A increases chemosensitivity to gemcitabine through upregulation of TGFBI in lung cancer cells. |
TGFBI |
| 46 |
2015 |
Knockdown of CUL4A inhibits invasion and induces apoptosis in osteosarcoma cells. |
ANCT, IHC, Lv-shCUL4A, OS |
| 47 |
2015 |
Recurrent Amplification at 13q34 Targets at CUL4A, IRS2, and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma. |
CN, iCCA, IRS2, TFDP1 |
| 48 |
2015 |
The COP9 signalosome is vital for timely repair of DNA double-strand breaks. |
CRL, DSBs, HRR |
| 49 |
2015 |
The Cullin 4A/B-DDB1-Cereblon E3 Ubiquitin Ligase Complex Mediates the Degradation of CLC-1 Chloride Channels. |
CRBN, DDB1 |
| 50 |
2014 |
CUL4A is overexpressed in human pituitary adenomas and regulates pituitary tumor cell proliferation. |
--- |
| 51 |
2014 |
CUL4A ubiquitin ligase: a promising drug target for cancer and other human diseases. |
--- |
| 52 |
2014 |
Cullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complex. |
CUL4, CUL4B, HIV, SIV, UNG2 |
| 53 |
2014 |
E3 ubiquitin ligase Cullin4B mediated polyubiquitination of p53 for its degradation. |
CUL4B |
| 54 |
2014 |
Interactions with DCAF1 and DDB1 in the CRL4 E3 ubiquitin ligase are required for Vpr-mediated G2 arrest. |
AGM, DCAF1, DDB1 |
| 55 |
2014 |
Lung tumourigenesis in a conditional Cul4A transgenic mouse model. |
CIP1, IHC |
| 56 |
2013 |
HIV relies on neddylation for ubiquitin ligase-mediated functions. |
UNG2, Vpr, Vpx |
| 57 |
2013 |
The CUL4A ubiquitin ligase is a potential therapeutic target in skin cancer and other malignancies. |
CDT1, DDB2, XPC |
| 58 |
2012 |
Pathogenic Role of the CRL4 Ubiquitin Ligase in Human Disease. |
CRL4, CUL4B |
| 59 |
2012 |
The Cul4A-DDB1 E3 ubiquitin ligase complex represses p73 transcriptional activity. |
DDB1 |
| 60 |
2011 |
Cullin-4ADNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis. |
DDB1 |
| 61 |
2011 |
Damage-specific DNA binding protein 1 (DDB1): a protein with a wide range of functions. |
CSA, DDB1, GG-NER, TC-NER |
| 62 |
2011 |
Transgenic mice for cre-inducible overexpression of the Cul4A gene. |
--- |
| 63 |
2010 |
De novo DNA methyltransferase DNMT3b interacts with NEDD8-modified proteins. |
--- |
| 64 |
2010 |
HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation. |
DCAF1, DDB1, HIV-1, UNG2 |
| 65 |
2009 |
Cul4A is an oncogene in malignant pleural mesothelioma. |
MPM |
| 66 |
2008 |
The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A. |
CUL4B, NER, UV-DDB, XP-E |
| 67 |
2007 |
HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase. |
DDB1, HIV-1, Vpr, VprBP |
| 68 |
2006 |
Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognition by XPC. |
DDB2, NER, UV, XP |
| 69 |
2006 |
DNA damage binding protein component DDB1 participates in nucleotide excision repair through DDB2 DNA-binding and cullin 4A ubiquitin ligase activity. |
CPD, DDB, NER |
| 70 |
2005 |
DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex. |
DDB2, XP, XP-E |
| 71 |
2005 |
Xeroderma pigmentosum complementation group E protein (XPE/DDB2): purification of various complexes of XPE and analyses of their damaged DNA binding and putative DNA repair properties. |
UV-DDB, XPV |
| 72 |
2004 |
Cul4A physically associates with MDM2 and participates in the proteolysis of p53. |
--- |
| 73 |
2004 |
Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase. |
AtDET1, DDB1, hDET1, ROC1 |
| 74 |
2002 |
Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components. |
STAT, SV5, Ub |
| 75 |
2002 |
TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas. |
CDC16, CGH, ESC, HCCs, PCR |
| 76 |
1999 |
Cullin 4A associates with the UV-damaged DNA-binding protein DDB. |
DDB |
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