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■ Abbreviation / Long Form : CysLTs / cysteinyl leukotrienes

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Total Number of Papers: 439
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Abbreviation:   CysLTs  (>> Co-occurring Abbreviation)
Long Form:   cysteinyl leukotrienes
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2022 A Dual Role for Cysteinyl Leukotriene Receptors in the Pathogenesis of Corneal Infection. ---
2022 Five-lipoxygenase-activating protein-mediated CYLD attenuation is a candidate driver in hepatic malignant lesion. 5-LO, AAI, CYLD, FLAP, HCC
2022 Leukotriene D4 accelerates antigen-mediated mast cell responses via the cysteinyl leukotriene 1 receptor. BMMCs, MCs
2022 Mechanisms by which dupilumab normalizes eicosanoid metabolism and restores aspirin-tolerance in AERD: A hypothesis. AERD, PGE2
2022 Neuroprotective effects of CysLTR antagonist on Streptococcus pneumoniae-induced meningitis in rats. SP
2021 Emerging role of cysteinyl LTs in cancer. ---
2021 Exercise-induced alterations in phospholipid hydrolysis, airway surfactant, and eicosanoids and their role in airway hyperresponsiveness in asthma. AHR, BAL, EIB, PGD2
2021 Oxidative biomarkers of exhaled breath condensate in adults exposed to traffic-related air pollution: a case-control study. EBC, IQR, TRAP
2021 Persistent Eosinophilic Inflammation in Adult Asthmatics with High Serum and Urine Levels of Leukotriene E4. AERD, ATA, LTRA
10  2021 Protectins PCTR1 and PD1 Reduce Viral Load and Lung Inflammation During Respiratory Syncytial Virus Infection in Mice. PCTR1, PD1, RSV, SPMs
11  2021 The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch. CysLT2R, DRG, LTC4
12  2021 Transcriptome Analysis Identifies Doublesex and Mab-3 Related Transcription Factor (DMRT3) in Nasal Polyp Epithelial Cells of Patients Suffering from Non-Steroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease (AERD). AERD, AERD, DMRT3, ELISA, IHC
13  2021 Tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation. DCs, IL-25, LTC4
14  2020 12-Oxo-10-glutathionyl-5,8,14-eicosatrienoic acid (TOG10), a novel glutathione-containing eicosanoid generated via the 12-lipoxygenase pathway in human platelets. AA, CTRs, DHA, EXs, GST, LTC4S, MCTRs, pt12-LOX
15  2020 5-lipoxygenase pathway and its downstream cysteinyl leukotrienes as potential therapeutic targets for Alzheimer's disease. AA, AD
16  2020 Aspirin-exacerbated respiratory disease. AERD, COX, IL-33, ILC2, PGE2
17  2020 Cellular interactions in aspirin-exacerbated respiratory disease. AERD, PGD2, PGE2
18  2020 Cellular Source of Cysteinyl Leukotrienes Following Chlorine Exposure. ---
19  2020 Cysteinyl leukotriene D4 (LTD4) promotes airway epithelial cell inflammation and remodelling. ALI, BAL, HFD, LTD4, OVA, SAECs
20  2020 Dysregulated metabolism of polyunsaturated fatty acids in eosinophilic allergic diseases. AA, DHA, ECRS, PUFAs
21  2020 Exosomes from MSCs overexpressing microRNA-223-3p attenuate cerebral ischemia through inhibiting microglial M1 polarization mediated inflammation. CysLT2R, MCAO/R, OGD
22  2020 Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1. CysLTR
23  2020 Leukotriene D4 paradoxically limits LTC4-driven platelet activation and lung immunopathology. LT
24  2020 Leukotriene D4 role in allergic asthma pathogenesis from cellular and therapeutic perspectives. ---
25  2020 Modulation of neuroinflammation by cysteinyl leukotriene 1 and 2 receptors: implications for cerebral ischemia and neurodegenerative diseases. ---
26  2020 Novel airway smooth muscle-mast cell interactions and a role for the TRPV4-ATP axis in non-atopic asthma. ASM, Ig, TRPV4
27  2020 Phase 2 trial of montelukast for prevention of pain in sickle cell disease. SCD
28  2020 Targeting E. coli invasion of the blood-brain barrier for investigating the pathogenesis and therapeutic development of E. coli meningitis. EGFR
29  2020 Trichomonas vaginalis-secreted cysteinyl leukotrienes promote migration, degranulation and MCP-1 production in mast cells. CysLTR, IL, LTB4, MCP-1, TvSP
30  2020 Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity. IL-25
31  2020 Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study. MMA, PGs, SA
32  2019 Adipocytokines leptin and adiponectin function as mast cell activity modulators. MCs, PI3K
33  2019 Cysteinyl leukotriene 1 receptor expression in nasal polyps. CRS
34  2019 Cysteinyl leukotriene metabolism of human eosinophils in allergic disease. ---
35  2019 Cysteinyl leukotriene receptor 2 drives lung immunopathology through a platelet and high mobility box 1-dependent mechanism. AERD, HMGB1, LTC4, RAGE
36  2019 Cysteinyl leukotriene receptor type 1 antagonist montelukast protects against injury of blood-brain barrier. BBB, EC, IL-1beta, IL-6, MMPs, OGD/R, TNF-alpha, ZO-1
37  2019 Cysteinyl maresins regulate the prophlogistic lung actions of cysteinyl leukotrienes. LMs, LT, MCTRs
38  2019 Generation and phenotype analysis of CysLTR1 L118F mutant mice. CysLTR1
39  2019 Implications of prostaglandin D2 and leukotrienes in exhaled breath condensates of asthma. EBCs, LTB4, PGD2-MOX
40  2019 Liquid chromatography-coupled mass spectrometry analysis of glutathione conjugates of oxygenated polyunsaturated fatty acids. AA, CTRs, DHA, EXs, LTC4, MCTRs, PCTRs, RCTRs
41  2019 Roles of cysteinyl leukotrienes and their receptors in immune cell-related functions. LTC4
42  2019 RPTPepsilon promotes M2-polarized macrophage migration through ROCK2 signaling and podosome formation. HMDMs, LTD4, PTPepsilon
43  2019 Suppression of aspirin-mediated eosinophil activation by prostaglandin E2: Relevance to aspirin and nonsteroidal anti-inflammatory drug hypersensitivity. AERD, EDN, LTB4, NSAIDs, PGE2
44  2019 The relationship between inflammatory markers and spirometric parameters in ACOS, Asthma, and COPD. COPD, IL-5, PGD2, PGE2
45  2019 Variants in the CYSLTR2 are associated with asthma, atopy markers and helminths infections in the Brazilian population. CYSLTR2
46  2018 A novel therapeutic potential of cysteinyl leukotrienes and their receptors modulation in the neurological complications associated with Alzheimer's disease. 5-LOX, AD, LTC4, LTD4, LTE4
47  2018 Advanced Glycation End-Products-, C-Type Lectin- and Cysteinyl/ Leukotriene-Receptors in Distinct Mesenchymal Stromal Cell Populations: Differential Transcriptional Profiles in Response to Inflammation. AT, BM, FSK, LTB4, MSCs, qRT-PCR, WJ
48  2018 Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes. CysLTR1, cysLTRs, OA, SA-beta-gal, TNF-alpha
49  2018 Comparison of the efficacy and mechanisms of intranasal budesonide, montelukast, and their combination in treatment of patients with seasonal allergic rhinitis. BD, ECP, FeNO, MNT, NCV, SAR, Th1, Treg
50  2018 CysLT1 receptor antagonist alleviates pathogenesis of collagen-induced arthritis mouse model. CIA, RA
51  2018 Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis. ECs, LLC, VE
52  2018 Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm. AAA, MIP-1alpha, MMP-9
53  2018 Cysteinyl leukotriene receptor 1 regulates glucose-stimulated insulin secretion (GSIS). cysLT1R, GSIS, RT-PCR
54  2018 Edaravone, a free radical scavenger, protects neuronal cells' mitochondria from ischemia by inactivating another new critical factor of the 5-lipoxygenase pathway affecting the arachidonic acid metabolism. 5-LOX, MCAO, OGD, OGD-R
55  2018 House dust mite drives proinflammatory eicosanoid reprogramming and macrophage effector functions. AAI, aMDM, HDM, MDM
56  2018 IL-33 Upregulates Cysteinyl Leukotriene Receptor Type 1 Expression in Human Peripheral Blood CD4+ T Lymphocytes. ---
57  2018 Inhibition of 5-lipoxygenase inhibitor zileuton in high-fat diet-induced nonalcoholic fatty liver disease progression model. FFA, HE, HFD, NAFLD, NAS
58  2018 Involvement and Possible Role of Eosinophils in Asthma Exacerbation. GM-CSF, ICAM, IL, LPS, RV, Th
59  2018 Leukotriene E4 induces airflow obstruction and mast cell activation through the cysteinyl leukotriene type 1 receptor. CysLT1, LT, PG, TX
60  2018 Lipid mediator Leukotriene D4-induces airway epithelial cells proliferation through EGFR/ERK1/2 pathway. EGF, LTD4, SAECs
61  2018 Multi-Walled Carbon Nanotubes Augment Allergic Airway Eosinophilic Inflammation by Promoting Cysteinyl Leukotriene Production. HDM, MWCNT
62  2018 Pathogenesis of NSAID-induced reactions in aspirin-exacerbated respiratory disease. AERD, PG
63  2018 Targeting lipid mediators in asthma: time for reappraisal. CRTH2
64  2017 5-LO inhibition ameliorates palmitic acid-induced ER stress, oxidative stress and insulin resistance via AMPK activation in murine myotubes. 5-LO, LTB4, PA
65  2017 Cysteinyl leukotriene E4 activates human group 2 innate lymphoid cells and enhances the effect of prostaglandin D2 and epithelial cytokines. LT, PGD2, TSLP
66  2017 Cysteinyl Leukotrienes as Potential Pharmacological Targets for Cerebral Diseases. ---
67  2017 Cysteinyl Leukotrienes in Eosinophil Biology: Functional Roles and Therapeutic Perspectives in Eosinophilic Disorders. CysLT1R, CysLT2R, CysLTRs
68  2017 Effects of leukotriene D4 nasal challenge on bronchial responsiveness and inflammation in asthmatic patients with allergic rhinitis. AR, BHR, FeNO, MCh
69  2017 Expression of cysteinyl leukotriene receptor GPR17 in eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps. CRSwNP, ECRS, non-ECRS
70  2017 High-affinity pan-specific monoclonal antibodies that target cysteinyl leukotrienes and show efficacy in an acute model of colitis. LTC4
71  2017 In Vivo Cysteinyl Leukotriene Release in Allergic and Nonallergic Immediate Hypersensitivity Reactions during Anesthesia. ---
72  2017 Leukotriene C4 Potentiates IL-33-Induced Group 2 Innate Lymphoid Cell Activation and Lung Inflammation. LTC4
73  2017 Leukotriene D4 induces chemotaxis in human eosinophilc cell line, EoL-1 cells via CysLT1 receptor activation. ---
74  2017 Leukotriene receptor antagonist attenuated airway inflammation and hyperresponsiveness in a double-stranded RNA-induced asthma exacerbation model. BAL, BALF, LTRA, OVA
75  2017 Montelukast reduces inhaled chlorine triggered airway hyperresponsiveness and airway inflammation in the mouse. AHR, BAL
76  2017 Prevalence of M75 Streptococcus pyogenes Strains Harboring slaA Gene in Patients Affected by Pediatric Obstructive Sleep Apnea Syndrome in Central Italy. GAS, MLST, OSAS, SLO
77  2017 Prolonged, acute suppression of cysteinyl leukotriene to reduce capsular contracture around silicone implants. IF, TGF
78  2017 Role of the Cysteinyl Leukotrienes in the Pathogenesis and Progression of Cardiovascular Diseases. 5-LO
79  2017 The inhibition of 5-Lipoxygenase (5-LO) products leukotriene B4 (LTB4) and cysteinyl leukotrienes (cysLTs) modulates the inflammatory response and improves cutaneous wound healing. 5-LO, CysLT, LTB4
80  2017 The role of cysteinyl leukotrienes and their receptors in refractory nasal polyps. CRSsNP, CRSwNP, NPs, SEB
81  2017 Type 2 Cysteinyl Leukotriene Receptors Drive IL-33-Dependent Type 2 Immunopathology and Aspirin Sensitivity. LTC4S
82  2017 Urine cysteinyl leukotriene levels in children with sleep disordered breathing before and after adenotonsillectomy. OSA, SDB, uLTE4
83  2016 A dual CysLT1/2 antagonist attenuates allergen-induced airway responses in subjects with mild allergic asthma. EAR, FEV1, LAR
84  2016 Advances in aspirin-exacerbated respiratory disease (AERD). AERD, COX, PGD2
85  2016 Aspirin Intolerance: Experimental Models for Bed-to-Bench. AERD, AIU, NSAID
86  2016 CysLT1 Receptor Is Protective against Oxidative Stress in a Model of Irritant-Induced Asthma. cysLT1R, Nrf2, WT
87  2016 Cysteinyl leukotriene correlated with 8-isoprostane levels as predictive biomarkers for sensory dysfunction in autism. CARS, ROC, SRS, SSP
88  2016 Development of smart cell-free and cell-based assay systems for investigation of leukotriene C4 synthase activity and evaluation of inhibitors. 5-LOX, AA, LTA4, LTC4S
89  2016 Exhaled breath condensate pH and cysteinyl leukotriens in patients with chronic cough secondary to acid gastroesophageal reflux. EBC
90  2016 Expression and localization of GPR99 in human nasal mucosa. ---
91  2016 Leukotriene B4 receptor type 2 protects against pneumolysin-dependent acute lung injury. 12-HHT, ALI, PLY
92  2016 Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99. CysLTRs, EPC, LTC4, LTC4S, MC
93  2016 Leukotriene E4 is a full functional agonist for human cysteinyl leukotriene type 1 receptor-dependent gene expression. CysLT1, ERK, LTE4
94  2016 Montelukast reduces seizures in pentylenetetrazol-kindled mice. PTZ
95  2016 Paediatric obstructive sleep apnoea syndrome (OSAS) is associated with tonsil colonisation by Streptococcus pyogenes. GAS, MyD88, OSAS, SLO, TLR4, TMCs, TRIF
96  2016 Preventive effect of genetic knockdown and pharmacological blockade of CysLT1R on lipopolysaccharide (LPS)-induced memory deficit and neurotoxicity in vivo. AD, LPS, MWM
97  2016 Respiratory, ocular and skin health in recreational and competitive swimmers: Beneficial effect of a new method to reduce chlorine oxidant derivatives. EBC, LTB4
98  2016 Role of Cysteinyl Leukotrienes in Allergic Rhinitis. CysLT1R, CysLT2R
99  2015 Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway. AERD, MCs
100  2015 Cysteinyl Leukotrienes (CysLTs): Role in Obesity-Induced Asthma. 5-LO, LTs