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■ Abbreviation / Long Form : EAAC1 / excitatory amino acid carrier 1

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Total Number of Papers: 127
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Abbreviation:   EAAC1  (>> Co-occurring Abbreviation)
Long Form:   excitatory amino acid carrier 1
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No. Year Title Co-occurring Abbreviation
2021 Effect of fumonisin B1 on oxidative stress and gene expression alteration of nutrient transporters in porcine intestinal cells. DMT1, FATP1, FATP4, FB1, GLUT2, PEPT1, ROS, SLC7A1, ZNT1
2021 Glutathione in the Brain. GTRAP3-18
2021 Protective Role of Glutathione in the Hippocampus after Brain Ischemia. ---
2021 Self-Regulation of Cerebral Metabolism and Its Neuroprotective Effect After Hypoxic-Ischemic Injury: Evidence From 1H-MRS. CK-BB, Cr, GCLC, GCPII, GS, HI, NAAG, NAAGS, NSPC
2021 [Mechanism of glutathione production in neurons]. ---
2021 [The neuroprotective role of EAAC1 in hippocampal injury following ischemia-reperfusion]. ---
2020 Early Neurotoxic Effects of Inorganic Arsenic Modulate Cortical GSH Levels Associated With the Activation of the Nrf2 and NFkappaB Pathways, Expression of Amino Acid Transporters and NMDA Receptors and the Production of Hydrogen Sulfide. CNS, GLAST, GLT-1, iAs, NF-kappaB, NMDA, Nrf2
2020 Early-life stress induces EAAC1 expression reduction and attention-deficit and depressive behaviors in adolescent rats. ELS, NMS
2020 Excitatory glutamate transporter EAAC1 as an important transporter of N-(2-[18F]fluoropropionyl)-L-glutamate in oncology PET imaging. PET
10  2020 Glial glutamate transporter GLT-1 determines susceptibility to spreading depression in the mouse cerebral cortex. CSD, GLAST, GLT-1, GLT-1 cKO
11  2020 NCX1 and EAAC1 transporters are involved in the protective action of glutamate in an in vitro Alzheimer's disease-like model. AD, NCX1, RA, TCA
12  2020 Neuregulin-1 inhibits CoCl2-induced upregulation of excitatory amino acid carrier 1 expression and oxidative stress in SH-SY5Y cells and the hippocampus of mice. EAATs, NRG1, ROS
13  2020 Role of Excitatory Amino Acid Carrier 1 (EAAC1) in Neuronal Death and Neurogenesis After Ischemic Stroke. ---
14  2020 The role of diurnal fluctuations in excitatory amino acid carrier 1 levels in post-ischemic hippocampal Zn2+ accumulation. ZT18
15  2019 A K+/Na+ co-binding state: Simultaneous versus competitive binding of K+ and Na+ to glutamate transporters. EAAT3
16  2019 Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma. GLAST, NAC, RGCs
17  2019 Genetically Encoded Halide Sensor-Based Fluorescent Assay for Rapid Screening of Glutamate Transport and Inhibition. EAAT2, EAATs, YFP
18  2018 A toll-like receptor 9 antagonist restores below-level glial glutamate transporter expression in the dorsal horn following spinal cord injury. GAT3, GLAST, GLT-1, LDH, ODN 2088, SC, TLR9
19  2018 EAAC1 gene deletion reduces adult hippocampal neurogenesis after transient cerebral ischemia. WT
20  2018 Effects of propofol and isoflurane on excitatory amino acid carrier 1 mRNA and glutathione protein levels in rat hippocampus. Nrf2
21  2018 Expression and functions of glutamate and gamma‑aminobutyric acid transporters in ischemic models. GABA, GAT1
22  2018 Neuregulin1 Attenuates H2O2-Induced Reductions in EAAC1 Protein Levels and Reduces H2O2-Induced Oxidative Stress. LDH, NRG1, ROS, SOD
23  2018 Systemic L-buthionine-S-R-sulfoximine administration modulates glutathione homeostasis via NGF/TrkA and mTOR signaling in the cerebellum. BBB, BSO, EAAT3, LAT1, mTOR, NGF, TrkA
24  2018 Thymol Improves Barrier Function and Attenuates Inflammatory Responses in Porcine Intestinal Epithelial Cells during Lipopolysaccharide (LPS)-Induced Inflammation. IL-8, LPS, PEPT1, ROS, SGLT1, TEER, TNF-alpha, ZO-1
25  2018 Topical Ripasudil Suppresses Retinal Ganglion Cell Death in a Mouse Model of Normal Tension Glaucoma. IOP, KO, MAPK, RGCs
26  2017 Edaravone suppresses retinal ganglion cell death in a mouse model of normal tension glaucoma. ALS, IOP, RGCs
27  2017 Effect of early weaning on the expression of excitatory amino acid transporter 1 in the jejunum and ileum of piglets. EAATs, Glu
28  2017 Ethanol (E) Impairs Fetal Brain GSH Homeostasis by Inhibiting Excitatory Amino-Acid Carrier 1 (EAAC1)-Mediated Cysteine Transport. Cys, gd, PCNs, SD
29  2017 OCD candidate gene SLC1A1/EAAT3 impacts basal ganglia-mediated activity and stereotypic behavior. EAAT3, OCD
30  2017 Pentylenetetrazol modulates redox system by inducing addicsin translocation from endoplasmic reticulum to plasma membrane in NG108-15 cells. DPPH, ER, GABAA, LDH, PTZ
31  2016 Decreased cysteine uptake by EAAC1 gene deletion exacerbates neuronal oxidative stress and neuronal death after traumatic brain injury. NAC, TBI
32  2016 Electrogenic Steps Associated with Substrate Binding to the Neuronal Glutamate Transporter EAAC1. ---
33  2016 Estrogen regulates excitatory amino acid carrier 1 (EAAC1) expression through sphingosine kinase 1 (SphK1) transacting FGFR-mediated ERK signaling in rat C6 astroglial cells. EAATs, FGF-2, FRS2alpha, SphK1
34  2015 Desflurane increased the activity of excitatory amino-acid carrier 1 (EAAC1) expressed in Xenopus oocytes. PI3K, PKC
35  2015 Glutathione in Cellular Redox Homeostasis: Association with the Excitatory Amino Acid Carrier 1 (EAAC1). ROS
36  2015 Neuregulin 1 Controls Glutamate Uptake by Up-regulating Excitatory Amino Acid Carrier 1 (EAAC1). NRG1, PFC, PV
37  2015 Protein Interacting with C-Kinase 1 Deficiency Impairs Glutathione Synthesis and Increases Oxidative Stress via Reduction of Surface Excitatory Amino Acid Carrier 1. PICK1, ROS
38  2015 Spermidine Ameliorates Neurodegeneration in a Mouse Model of Normal Tension Glaucoma. 4-HNE, IOP, KO
39  2015 Tangzhining exhibits a protective effect against cognitive dysfunction in diabetic rats. GAD, Glu, NMDA, TCM, TZN
40  2014 Brimonidine prevents neurodegeneration in a mouse model of normal tension glaucoma. BMD, IOP, NR2B, RGCs
41  2014 Identification of tomoregulin-1 as a novel addicsin-associated factor. ER, GTRAP3-18, TR1
42  2014 Renin-angiotensin system regulates neurodegeneration in a mouse model of normal tension glaucoma. AT1R, iNOS, IOP, LPS, RGCs, TLR4
43  2014 Rhythmic oscillations of the microRNA miR-96-5p play a neuroprotective role by indirectly regulating glutathione levels. ---
44  2014 The excitatory amino acid carrier 1 (EAAC1) in the rat nucleus of the solitary tract: subcellular localization suggests no major role in glutamate clearance. ---
45  2013 Changes in the expression of the glutamate transporter EAAT3/EAAC1 in health and disease. EAATs
46  2013 Neuroprotective properties of the excitatory amino acid carrier 1 (EAAC1). CNS, EAATs
47  2013 Oral administration of MSG increases expression of glutamate receptors and transporters in the gastrointestinal tract of young piglets. BW, GLAST-1, GLT-1, MSG
48  2012 Increased neuronal glutathione and neuroprotection in GTRAP3-18-deficient mice. GTRAP3-18
49  2012 Inhibition of GTRAP3-18 may increase neuroprotective glutathione (GSH) synthesis. GTRAP3-18
50  2012 Molecular cloning and expression profiling of excitatory amino acid carrier 1 in suckling Huanjiang mini-piglets with large or small body weight at birth. ---
51  2012 Physical and functional interaction of NCX1 and EAAC1 transporters leading to glutamate-enhanced ATP production in brain mitochondria. EAATs
52  2012 Whiplash-like facet joint loading initiates glutamatergic responses in the DRG and spinal cord associated with behavioral hypersensitivity. DRG, mGluR5, PKCepsilon
53  2011 Caffeine and uric acid mediate glutathione synthesis for neuroprotection. UA
54  2011 Expression, distribution and glutamate uptake activity of high affinity-excitatory aminoacid transporters in in vitro cultures of embryonic rat dorsal root ganglia. DRG, GLT-1
55  2011 Glutamatergic alterations and mitochondrial impairment in a murine model of Alzheimer disease. AD, ATP, FC, GFAP, GLAST, GLT-1, HIPP, SNAP-25, VGLUT1
56  2011 Group I mGluR-regulated translation of the neuronal glutamate transporter, excitatory amino acid carrier 1. DHPG, SE
57  2011 Modulation of neuronal glutathione synthesis by EAAC1 and its interacting protein GTRAP3-18. GTRAP3-18
58  2010 Age-dependent modifications in the mRNA levels of the rat excitatory amino acid transporters (EAATs) at 48hour reperfusion following global ischemia. EAATs, I/R
59  2010 Corticosterone decreases the activity of rat glutamate transporter type 3 expressed in Xenopus oocytes. EAAT3, PI3K, PKC, PMA
60  2010 Expression of multiple glutamate transporter splice variants in the rodent testis. EAAT4, GLAST, GLT-1, GLT1a
61  2010 Functional roles of high-affinity glutamate transporters in cochlear afferent synaptic transmission in the mouse. DHK, GLAST, GLT-1, SOS, TBOA
62  2010 Glutamate transporters are differentially expressed in the hippocampus during the early stages of one-day spatial learning task. GLAST, GLT-1
63  2010 Mechanism of cation binding to the glutamate transporter EAAC1 probed with mutation of the conserved amino acid residue Thr101. ---
64  2010 The glutamate transporter excitatory amino acid carrier 1 associates with the actin-binding protein alpha-adducin. HA, PKC
65  2009 Acute treatment with diphenyl diselenide inhibits glutamate uptake into rat hippocampal slices and modifies glutamate transporters, SNAP-25, and GFAP immunocontent. DAPI, GFAP, GLAST, SNAP-25, VGLUT1
66  2009 Evidence that increased 5-HT release evokes region-specific effects on blood-oxygenation level-dependent functional magnetic resonance imaging responses in the rat brain. BOLD, fMRI, GAD
67  2009 Interleukin-1 attenuates normal tension glaucoma-like retinal degeneration in EAAC1-deficient mice. GLAST, IL-1, NTG, RGCs, WT
68  2009 PKC induces internalization and retention of the EAAC1 glutamate transporter in recycling endosomes of MDCK cells. MDCK, PKC, PMA
69  2009 Protein kinase C-dependent trafficking of glutamate transporters excitatory amino acid carrier 1 and glutamate transporter 1b in cultured cerebellar granule cells. CGCs, PKC
70  2009 Simulated whiplash modulates expression of the glutamatergic system in the spinal cord suggesting spinal plasticity is associated with painful dynamic cervical facet loading. mGluR5
71  2009 Suppressive effects of intrathecal granulocyte colony-stimulating factor on excessive release of excitatory amino acids in the spinal cerebrospinal fluid of rats with cord ischemia: role of glutamate transporters. EAAs, G-CSF, GLAST, GLT-1, GTs, i.t
72  2008 A dominant role of GTRAP3-18 in neuronal glutathione synthesis. ---
73  2008 Amitriptyline induces nuclear transcription factor-kappaB-dependent glutamate transporter upregulation in chronic morphine-infused rats. CSF, GLAST, GLT-1, NF-kappaB
74  2008 Bradykinin stimulates glutamate uptake via both B1R and B2R activation in a human retinal pigment epithelial cells. ARPE, B1R, B2R, BK, COX, EAAT4, PKC
75  2008 C6 glioma cells differentiated by retinoic acid overexpress the glutamate transporter excitatory amino acid carrier 1 (EAAC1). ATRA, EAA
76  2008 GTRAP3-18 serves as a negative regulator of Rab1 in protein transport and neuronal differentiation. ER, GTRAP3-18, VSV-G
77  2008 Molecular regulation of antioxidant ability in the hippocampus of EL mice. HIPP
78  2008 Regulation of neuronal glutathione synthesis. EAAT
79  2007 Caveolin-1 regulates the delivery and endocytosis of the glutamate transporter, excitatory amino acid carrier 1. Cav-1
80  2007 Constitutive endocytosis and recycling of the neuronal glutamate transporter, excitatory amino acid carrier 1. EEA1
81  2007 Identification of fasting-induced genes in the rat hypothalamus: relationship with neuroprotection. cDNA, FTH1, PKCbeta, UBE2D3
82  2007 N-methyl-D-aspartate receptor-dependent regulation of the glutamate transporter excitatory amino acid carrier 1. NMDA
83  2007 Neural localization of addicsin in mouse brain. CNS, GABA, GTRAP3-18, PRA
84  2007 Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction. MPTP, NAC, PD, SN
85  2007 Prenatal exposure to the cannabinoid receptor agonist WIN 55,212-2 increases glutamate uptake through overexpression of GLT1 and EAAC1 glutamate transporter subtypes in rat frontal cerebral cortex. Delta9-THC, GLT-1, GluTs, ir
86  2007 Proteomic analyses of retina of excitatory amino acid carrier 1 deficient mice. ---
87  2007 Regulation of glutathione synthesis via interaction between glutamate transport-associated protein 3-18 (GTRAP3-18) and excitatory amino acid carrier-1 (EAAC1) at plasma membrane. GTRAP3-18, HEK
88  2007 Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1. EAATs, ER
89  2006 Alteration of the glutamate and GABA transporters in the hippocampus of the Niemann-Pick disease, type C mouse using proteomic analysis. NPC
90  2006 Different mechanisms exist for the plasticity of glutamate reuptake during early long-term potentiation (LTP) and late LTP. LTP
91  2006 Regulation of the glutamate transporter EAAC1 by expression and activation of delta-opioid receptor. DOR
92  2006 Syntaxin 1A promotes the endocytic sorting of EAAC1 leading to inhibition of glutamate transport. GABA
93  2006 Transient ischaemia affects plasma membrane glutamate transporter, not vesicular glutamate transporter, expressions in the gerbil hippocampus. GLAST, GLT-1, VGLUT
94  2006 Unique anti-apoptotic activity of EAAC1 in injured motor neurons. HCCS, XIAP
95  2005 A carboxyl-terminal determinant of the neuronal glutamate transporter, EAAC1, is required for platelet-derived growth factor-dependent trafficking. PDGF
96  2005 Excitatory amino acid transporters expressed by synovial fibroblasts in rats with collagen-induced arthritis. Glu
97  2005 Expression profile of addicsin/GTRAP3-18 mRNA in mouse brain. GTRAP3-18
98  2005 Functional expression of particular isoforms of excitatory amino acid transporters by rodent cartilage. EAATs, GLAST, GLT-1, RT-PCR
99  2005 Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse. ---
100  2004 Evidence of neuronal excitatory amino acid carrier 1 expression in rat dorsal root ganglion neurons and their central terminals. CGRP