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■ Abbreviation / Long Form : EGR2 / early growth response 2

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Total Number of Papers: 128
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Abbreviation:   EGR2  (>> Co-occurring Abbreviation)
Long Form:   early growth response 2
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No. Year Title Co-occurring Abbreviation
2022 Downregulation of mmu_circ_0000943 ameliorates renal ischemia reperfusion-triggered inflammation and oxidative stress via regulating mmu-miR-377-3p/Egr2 axis. AKI, circRNAs, IRI, RIP
2022 EGR2 Deletion Suppresses Anti-DsDNA Autoantibody and IL-17 Production in Autoimmune-Prone B6/lpr Mice: A Differential Immune Regulatory Role of EGR2 in B6/lpr Versus Normal B6 Mice. ---
2022 EGR2 is a hub-gene in myocardial infarction and aggravates inflammation and apoptosis in hypoxia-induced cardiomyocytes. DEGs, GO, KEGG, MI, PPI
2022 EGR2-related mixed demyelinating and axonal Charcot-Marie-Tooth disease: An electrodiagnostic, nerve imaging, and histological study. CMT
2022 Susceptibility to kidney fibrosis in mice is associated with early growth response-2 protein and tissue inhibitor of metalloproteinase-1 expression. TGF-beta1, TIMP-1, UUO
2021 Characterization of an Expanded IL-10-Producing-Suppressive T Cell Population Associated with Immune Tolerance. GITR, IFN, Ig, IL, Th1
2021 Early growth response 2 (EGR2) is a novel regulator of the senescence programme. DS HMECs
2021 Effective in vitro differentiation of adipose-derived stem cells into Schwann-like cells with folic acid supplementation. ADSCs, p75NTR, PNI, S100B, SC, SLC
2021 EGR2-mediated regulation of m6A reader IGF2BP proteins drive RCC tumorigenesis and metastasis via enhancing S1PR3 mRNA stabilization. ChIP-qPCR, IGF2BPs, m6A, MERIP-qPCR, RCC, S1PR3, TF, WTAP
10  2021 Extracellular Vesicle-Derived microRNA-410 From Mesenchymal Stem Cells Protects Against Neonatal Hypoxia-Ischemia Brain Damage Through an HDAC1-Dependent EGR2/Bcl2 Axis. BCL2, EVs, HDAC1, HIBD, HUC, miR, mNSS, MSCs, OGD
11  2021 Functional genomics study of protein inhibitor of activated STAT1 in mouse hippocampal neuronal cells revealed by RNA sequencing. AD, bHLH, Egr-1, EGR3, Fos, FOSL1, PIAS1, SUMO, TFBS, zf-C2H2
12  2021 Landscape and Dynamics of the Transcriptional Regulatory Network During Natural Killer Cell Differentiation. ATAC-seq, FOSL2, NK, TF
13  2021 MicroRNA-17-5p inhibits thyroid cancer progression by suppressing Early growth response 2 (EGR2). TC
14  2021 Silencing long non-coding RNA MIAT ameliorates myocardial dysfunction induced by myocardial infarction via MIAT/miR-10a-5p/EGR2 axis. lncRNA, MI, MIAT, miR-10a-5p
15  2021 The epigenetic pioneer EGR2 initiates DNA demethylation in differentiating monocytes at both stable and transient binding sites. IRF4, MAC, Mo, TF
16  2021 The YAP/HIF-1alpha/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation. HIF-1alpha, miR-182, Th17, YAP
17  2020 Bi-allelic mutations in EGR2 cause autosomal recessive demyelinating neuropathy by disrupting the EGR2-NAB complex. ZnF
18  2020 Deficiency in the frequency and function of Tr1 cells in IgAV and the possible role of IL-27. IgAV, Tr1
19  2020 Early growth response genes 2 and 3 induced by AP-1 and NF-kappaB modulate TGF-beta1 transcription in NK1.1- CD4+ NKG2D+ T cells. NK
20  2020 EGR2 is elevated and positively regulates inflammatory IFNgamma production in lupus CD4+ T cells. ---
21  2020 Mineral trioxide aggregate suppresses pro-inflammatory cytokine expression via the calcineurin/nuclear factor of activated T cells/early growth response 2 pathway in lipopolysaccharide-stimulated macrophages. CaSR, IL, LPS, MTA, NF-kappaB, NFAT, SOCS3
22  2020 Overexpressed microRNA-539-5p inhibits inflammatory response of neurons to impede the progression of cerebral ischemic injury by histone deacetylase 1. HDAC1, JNK, OGD
23  2020 The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization. IL-4, TFs
24  2019 A de novo EGR2 variant, c.1232A > G p.Asp411Gly, causes severe early-onset Charcot-Marie-Tooth Neuropathy Type 3 (Dejerine-Sottas Neuropathy). CMT, PMP22, WES
25  2019 A novel family with axonal Charcot-Marie-Tooth disease caused by a mutation in the EGR2 gene. CHN, CMT1D, DSS
26  2019 LINC01939 inhibits the metastasis of gastric cancer by acting as a molecular sponge of miR-17-5p to regulate EGR2 expression. GC, lncRNAs
27  2019 MicroRNAs 93-5p, 106b-5p, 17-5p, and 140-5p target the expression of early growth response protein 2 in Schwann cells. miRNAs, SCs
28  2019 [Knockout of TLR2 gene attenuates insulin resistance and promotes M2 polarization of macrophages in mice]. GTT, ITT, TLR2, WT
29  2018 Coarse particulate matter (PM2.5-10) in Los Angeles Basin air induces expression of inflammation and cancer biomarkers in rat brains. PM
30  2018 DHTKD1 Deficiency Causes Charcot-Marie-Tooth Disease in Mice. 2-AAA, 2-KAA, AMOXAD, CMT, MPZ
31  2018 Early Growth Response Gene 2-Expressing CD4+LAG3+ Regulatory T Cells: The Therapeutic Potential for Treating Autoimmune Diseases. IL, LAG3
32  2018 MicroRNA-20a promotes proliferation and invasion by directly targeting early growth response 2 in non-small cell lung carcinoma. miR-20a, NSCLC
33  2018 Progression of myocardial ischemia leads to unique changes in immediate-early gene expression in the spinal cord dorsal horn. MI, TNFAIP3
34  2017 Analysis of neural crest cells from Charcot-Marie-Tooth disease patients demonstrates disease-relevant molecular signature. CMT, GSTT2, iPSCs, MPZ, PMP22
35  2017 Developmental Control of NRAMP1 (SLC11A1) Expression in Professional Phagocytes. CTCF, HIFs, IRF-1, SE, SNPs, STAT1, TFs
36  2017 Influences of RFA combined with TACE on the HIF-1alpha and EGR level of patients with primary hepatic carcinoma. AFP, RFA
37  2017 MiR-150-5p regulates EGR2 to promote the development of chronic rhinosinusitis via the DC-Th axis. CRS, DCs, ELISA, qRT-PCR
38  2017 Overexpression of Truncated Human DISC1 Induces Appearance of Hindbrain Oligodendroglia in the Forebrain During Development. DISC1, LAMA1, MPZ, NKX2.2, OLG, SZ
39  2017 Regulation of early growth response 2 expression by secreted frizzled related protein 1. SFRP1
40  2017 The Lysine Acetyltransferase GCN5 Is Required for iNKT Cell Development through EGR2 Acetylation. GCN5, IL, iNKT, PLZF
41  2017 WNK lysine deficient protein kinase 1 regulates human endometrial stromal cell decidualization, proliferation, and migration in part through mitogen-activated protein kinase 7. HESCs, IGFBP1, IL15, IL1B, ITGA2, ITGA4, ITGB3, MAPK7, PRL, SMAD3, TGF-beta, WNK1
42  2016 Analysis of the zebrafish sox9b promoter: Identification of elements that recapitulate organ-specific expression of sox9b. CNEs, HIF1alpha, SOX9
43  2016 Cognitive deficits triggered by early life stress: The role of histone deacetylase 1. BDNF, HDAC
44  2016 Congenital hypomyelinating neuropathy due to the association of a truncating mutation in PMP22 with the classical HNPP deletion. MPZ, PMP22
45  2016 Cooperation between somatic mutations and germline susceptibility variants in tumorigenesis - a dangerous liaison. ---
46  2016 Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-beta3 production. LTBP, SLE
47  2016 EGR2 is a gonadotropin-induced survival factor that controls the expression of IER3 in ovarian granulosa cells. ChIP, EBEs, EMSA, IER3, Mcl-1
48  2016 Emerging roles of Egr2 and Egr3 in the control of systemic autoimmunity. ---
49  2016 Expression of Early Growth Response Gene-2 and Regulated Cytokines Correlates with Recovery from Guillain-Barre Syndrome. GBS
50  2016 Expression profile analysis based on DNA microarray for patients undergoing off-pump coronary artery bypass surgery. DEGs, FOS, GEO, GSEA, OPCAB, PCA, PPI
51  2016 Identification of Differentially Expressed Genes Associated with Litter Size in Berkshire Pig Placenta. DEGs, GO, PHEROC, RNA-Seq
52  2016 MicroRNA-17-5p promotes gastric cancer proliferation, migration and invasion by directly targeting early growth response 2. GC, miR-17-5p
53  2016 Sustained Local Release of NGF from a Chitosan-Sericin Composite Scaffold for Treating Chronic Nerve Compression. CNC, GDNF, IL-1beta, NCAM, NCV, NGF, TNF-alpha
54  2015 Early Growth Response Genes 2 and 3 Regulate the Expression of Bcl6 and Differentiation of T Follicular Helper Cells. BCL6, GCs, Tfh
55  2015 Microprocessor complex subunit DiGeorge syndrome critical region gene 8 (Dgcr8) is required for schwann cell myelination and myelin maintenance. cKO, Dgcr8, SCs, Shh, SOX2
56  2015 MicroRNA‑20a promotes the proliferation and cell cycle of human osteosarcoma cells by suppressing early growth response 2 expression. miRNAs, OS
57  2015 miR-330-3p controls cell proliferation by targeting early growth response 2 in non-small-cell lung cancer. miRNAs, NSCLC
58  2015 Resequencing of early growth response 2 (EGR2) gene revealed a recurrent patient-specific mutation in schizophrenia. ---
59  2015 T-cell activation and early gene response in dogs. Egr-1, FOS, HEMGN, PHA, PLK2, PLK3, PMAIP1, qRT-PCR
60  2014 CD26-mediated induction of EGR2 and IL-10 as potential regulatory mechanism for CD26 costimulatory pathway. ---
61  2014 Cytokine-induced sleep: Neurons respond to TNF with production of chemokines and increased expression of Homer1a in vitro. NREM
62  2014 Definition of a Family of Tissue-Protective Cytokines Using Functional Cluster Analysis: A Proof-of-Concept Study. EPO
63  2014 EGR2 is critical for peripheral naive T-cell differentiation and the T-cell response to influenza. cKO
64  2013 A role for miR-142-3p in colony-stimulating factor 1-induced monocyte differentiation into macrophages. CMML, CSF-1, miRNAs, NGFI-A
65  2013 Distal segment extracts of the degenerated rat sciatic nerve induce bone marrow stromal cells to express Schwann cell markers in vitro. DS, GFAP, MSCs, PS
66  2013 Early growth response 2 (Egr2) plays opposing roles in committing C3H10T1/2 stem cells to adipocytes and smooth muscle-like cells. BMP
67  2013 Early growth response-2 signaling mediates immunomodulatory effects of human multipotential stromal cells. IDO1, IL-6, LIF, MSC
68  2013 Egr-2 transcription factor is required for Blimp-1-mediated IL-10 production in IL-27-stimulated CD4+ T cells. IL-27
69  2013 Egr2 induced during DC development acts as an intrinsic negative regulator of DC immunogenicity. CTL, DCs, Egr2-KD, MHC, STAT5
70  2013 Egr2-dependent gene expression profiling and ChIP-Seq reveal novel biologic targets in T cell anergy. DGK, LAG3, Sema7A
71  2013 Epidermal growth factor receptor (EGFR) signaling promotes proliferation and survival in osteoprogenitors by increasing early growth response 2 (EGR2) expression. EGFR
72  2013 Erythropoietin (EPO) increases myelin gene expression in CG4 oligodendrocyte cells through the classical EPO receptor. EPO, EPOR, MBP, MOG
73  2013 Involvement of miR-20a in promoting gastric cancer progression by targeting early growth response 2 (EGR2). GC, miRNAs
74  2013 Lack of association of EGR2 variants with bipolar disorder in Japanese population. ---
75  2013 Mast cell FcepsilonRI-induced early growth response 2 regulates CC chemokine ligand 1-dependent CD4+ T cell migration. ---
76  2013 MiR-224 impairs adipocyte early differentiation and regulates fatty acid metabolism. ACSL4, miRNAs, mRNAs
77  2013 Primary gene response to mechanical loading in healing rat Achilles tendons. Egr-1, qRT-PCR, Rgs1
78  2012 A novel EGR2 mutation within a family with a mild demyelinating form of Charcot-Marie-Tooth disease. CMT
79  2012 Early growth response 2 negatively modulates osteoclast differentiation through upregulation of Id helix-loop-helix proteins. BMMs, HLH, Ids, NAB2, NFATc1, RANKL
80  2012 Genetic epidemiology of Charcot-Marie-Tooth disease. CMT, CMT1, CMT2, Cx32, dHMN, DSS, Mfn2, MPZ, PMP22, SIMPLE
81  2012 IRES-dependent translation of egr2 is induced under inflammatory conditions. IRESs, ITAFs, PTB
82  2012 Regulation of the bovine SCD5 promoter by EGR2 and SREBP1. SCD2, SREBP1a
83  2012 Roles of LAG3 and EGR2 in regulatory T cells. FOXP3, IL, IL-2, iTregs, LAG3, nTregs
84  2012 Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo. DGK
85  2012 Vincristine exacerbates asymptomatic Charcot-Marie-tooth disease with a novel EGR2 mutation. CMT, PMP22, VCR
86  2011 Early growth response gene-2 (Egr-2) regulates the development of B and T cells. SP
87  2011 Genetic association of the EGR2 gene with bipolar disorder in Korea. BD, SNPs, SPR
88  2010 CD4+CD25-LAG-3+ T cells in mouse and human. ---
89  2010 Genetic epidemiology of Charcot-Marie-Tooth in the general population. CMT, Cx32, MCV, Mfn2, MPZ, PMP22, SIMPLE
90  2010 Identification and characterization of early growth response 2, a zinc-finger transcription factor, as a p53-regulated proapoptotic gene. ---
91  2010 Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus. RA, SLE
92  2009 CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2. LAG-3
93  2009 The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells. NKT
94  2009 [Experimental identification of drugs with function of targeted up-regulating ID4 expression: bioinformatics-based prediction and preliminary validation]. ER, GR, WT1
95  2008 Altered brain gene expression profiles associated with the pathogenesis of phenylketonuria in a mouse model. Kl, PAH, PKU, PRLR, SOSTDC1, TTR
96  2008 Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease. IFN, IL
97  2008 Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism. MeCP2, RTT
98  2008 Toxoplasma gondii rhoptry discharge correlates with activation of the early growth response 2 host cell transcription factor. ---
99  2006 Cloning, chromosomal localization and expression patterns of porcine Kruppel-like factors 4, -5, -7 and the early growth response factor 2. CDS, KLF
100  2006 Pathomechanisms of mutant proteins in Charcot-Marie-Tooth disease. CMT, DNM2, GDAP1, NfL