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■ Abbreviation / Long Form : FAAH / fatty acid amide hydrolase

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Total Number of Papers: 1326
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Abbreviation:   FAAH  (>> Co-occurring Abbreviation)
Long Form:   fatty acid amide hydrolase
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2021 A systematic review and meta-analysis of cannabis-based medicines, cannabinoids and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain. CBD, MGL, SMD
2021 A systematic, integrative review of the effects of the endocannabinoid system on inflammation and neurogenesis in animal models of affective disorders. CBRs, eCB
2021 Analgesic and Anticancer Activity of Benzoxazole Clubbed 2-Pyrrolidinones as Novel Inhibitors of Monoacylglycerol Lipase. GBP, MAGL
2021 Anti-Inflammatory Effects of Fatty Acid Amide Hydrolase Inhibition in Monocytes/Macrophages from Alzheimer's Disease Patients. AD, eCB
2021 Anticancer Potential of Small-Molecule Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase. 2-AG, AEA, MAGL
2021 Behavioral Battery for Testing Candidate Analgesics in Mice. II. Effects of Endocannabinoid Catabolic Enzyme Inhibitors and ∆9-Tetrahydrocannabinol. eCB, MAGL
2021 Cannabidiol regulates CB1-pSTAT3 signaling for neurite outgrowth, prolongs lifespan, and improves health span in Caenorhabditis elegans of Aβ pathology models. AD, C. elegans, CaMKII, CB1R, CBD
2021 Chronic Inhibition of FAAH Reduces Depressive-Like Behavior and Improves Dentate Gyrus Proliferation after Chronic Unpredictable Stress Exposure. AEA, BDNF, CUS, HPA
2021 Comorbid anxiety-like behavior in a rat model of colitis is mediated by an upregulation of corticolimbic fatty acid amide hydrolase. AEA, eCB
10  2021 Design and synthesis of new carbamates as inhibitors for fatty acid amide hydrolase and cholinesterases: Molecular dynamic, in vitro and in vivo studies. ACh, AChE, AD, BuChE, ChEIs, ChEs
11  2021 Distinct Activity of Endocannabinoid-Hydrolyzing Enzymes MAGL and FAAH in Key Regions of Peripheral and Central Nervous System Implicated in Migraine. ABPP, ECS, MAGL
12  2021 Effects of Chlorpyrifos on Serine Hydrolase Activities, Lipid Mediators, and Immune Responses in Lungs of Neonatal and Adult Mice. ABPP, AChE, CES, CPF, eCB, LPS, MAGL, OP, WT
13  2021 Elevated Brain Fatty Acid Amide Hydrolase Induces Depressive-Like Phenotypes in Rodent Models: A Review. MDD
14  2021 Fatty acid amide hydrolase binding is inversely correlated with amygdalar functional connectivity: a combined positron emission tomography and magnetic resonance imaging study in healthy individuals. dACC, PET, sgvmPFC
15  2021 Fear extinction learning and anandamide: an fMRI study in healthy humans. AEA, ECS, fMRI, SNP
16  2021 GPR18 drives FAAH inhibition-induced neuroprotection against HIV-1 Tat-induced neurodegeneration. AEA, HAND, HIV-1, MCM
17  2021 Heritability and family-based GWAS analyses of the N-acyl ethanolamine and ceramide plasma lipidome. 2SMR, Cer, CVD, GWAS, NAE
18  2021 Investigating the role of CB1 endocannabinoid transmission in the anti-fear and anxiolytic-like effects of ventromedial prefrontal cortex deep brain stimulation. BLA, DBS, vmPFC
19  2021 Late effects of early weaning on food preference and the dopaminergic and endocannabinoid systems in male and female rats. ECS, EW, NAc
20  2021 Lower amygdala fatty acid amide hydrolase in violent offenders with antisocial personality disorder: an [11C]CURB positron emission tomography study. ASPD, ECS
21  2021 Non-clinical toxicology evaluation of BIA 10-2474. ---
22  2021 Para-Aminobenzohydrazide Derivatives as Fatty Acid Amide Hydrolase Inhibitors: Design, Synthesis and Biological Evaluation. ---
23  2021 PF-3845, a Fatty Acid Amide Hydrolase Inhibitor, Directly Suppresses Osteoclastogenesis through ERK and NF-κB Pathways In Vitro and Alveolar Bone Loss In Vivo. ERK, MEK, NF-kappaB, NFATc1, RAF, RANKL
24  2021 Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development. CB1R, ECS, MAGL, PET
25  2021 Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis. Mtb, PheRS
26  2021 Region-specific dysregulation of endocannabinoid system in learned helplessness model of depression. DAGLalpha, ECS, GPR55, TRPV1
27  2021 Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents. ---
28  2021 Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex. 2-AG, AEA, DA, EPM, FST, LDT, MAGL, mPFC, TST
29  2021 Tart cherry (Prunus cerasus L.) dietary supplement modulates visceral adipose tissue CB1 mRNA levels along with other adipogenesis-related genes in rat models of diet-induced obesity. HFD, TRPV1
30  2021 The Absence of the Transient Receptor Potential Vanilloid 1 Directly Impacts on the Expression and Localization of the Endocannabinoid System in the Mouse Hippocampus. CB1R, CRIP1a, MAGL, ML, MPP, TRPV1
31  2021 The effects of fatty acid amide hydrolase inhibition and monoacylglycerol lipase inhibition on habit formation in mice. 2-AG, CB1R, MAGL
32  2021 Untapped endocannabinoid pharmacological targets: pipe dream or pipeline? 2-AG, ABHD6, DAGL-beta, DAGLalpha, MAGL
33  2020 A CNS-Targeting Prodrug Strategy for Nuclear Receptor Modulators. CNS
34  2020 A perspective review on fatty acid amide hydrolase (FAAH) inhibitors as potential therapeutic agents. ---
35  2020 A Polyphenols-Rich Extract from Moricandia sinaica Boiss. Exhibits Analgesic, Anti-Inflammatory and Antipyretic Activities In Vivo. ---
36  2020 Advances in the discovery of fatty acid amide hydrolase inhibitors: what does the future hold? MTDL
37  2020 An adaptive randomized clinical trial in interstitial cystitis/bladder pain syndrome evaluating efficacy of ASP3652 and the relationship between disease characteristics and Hunner's lesions. HL, IC/BPS, MDP
38  2020 An endocannabinoid catabolic enzyme FAAH and its paralogs in an early land plant reveal evolutionary and functional relationship with eukaryotic orthologs. ---
39  2020 Anandamide Signaling Augmentation Rescues Amygdala Synaptic Function and Comorbid Emotional Alterations in a Model of Epilepsy. AEA, BLA, eCB
40  2020 Antidepressant-like effects of pharmacological inhibition of FAAH activity in socially isolated female rats. BDNF
41  2020 Antidepressant-like effects of URB597 and JZL184 in male and female rats exposed to early life stress. BDNF, eCB, ELS, MAGL, NAc
42  2020 ASP8477, a fatty acid amide hydrolase inhibitor, exerts analgesic effects in rat models of neuropathic and dysfunctional pain. AMPA, NMDA
43  2020 Association of cannabinoid receptor genes (CNR1 and CNR2) polymorphisms and panic disorder. ECS, PD, SNPs
44  2020 Blockade of the endovanilloid receptor, TRPV1, and of the endocannabinoid enzyme, FAAH, within the nucleus accumbens shell elicits anxiolytic-like effects in male rats. CB1R, ECS, EPM, NAc shell, TRPV1
45  2020 Brain region-dependent changes in the expression of endocannabinoid-metabolizing enzymes in rats following antidepressant drugs. DAGLalpha, eCB, MAGL, NAPE-PLD
46  2020 Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation, and Nrf2 activation in a toxic model combining hyperglycemia+Abeta1-42 peptide in rat hippocampal neurons. 2-AG, AD, AEA, ECS, ROS
47  2020 Characterization of the peripheral FAAH inhibitor, URB937, in animal models of acute and chronic migraine. CGRP, NTG, PEA, PPAR-a
48  2020 Chinese Herbal Medicine (MaZiRenWan) Improves Bowel Movement in Functional Constipation Through Down-Regulating Oleamide. CSBM, FC, UPLC-MS
49  2020 Chronic Cannabidiol Administration Fails to Diminish Blood Pressure in Rats with Primary and Secondary Hypertension Despite Its Effects on Cardiac and Plasma Endocannabinoid System, Oxidative Stress and Lipid Metabolism. BP, CBD, HR
50  2020 Citral Inhibits the Inflammatory Response and Hyperalgesia in Mice: The Role of TLR4, TLR2/Dectin-1, and CB2 Cannabinoid Receptor/ATP-Sensitive K+ Channel Pathways. CB1R, CB2R, COX-2, LPS, NF-kappaB, PPAR, TLR, TRP
51  2020 Classics in Neuroimaging: Imaging the Endocannabinoid Pathway with PET. ECS, MAGL, PET
52  2020 Colonization with the commensal fungus Candida albicans perturbs the gut-brain axis through dysregulation of endocannabinoid signaling. AEA, CORT, eCB, GI, HPA
53  2020 Comparison of endocannabinoids levels, FAAH gene polymorphisms, and appetite regulatory substances in women with and without binge eating disorder: a cross- sectional study. 2-AG, AEA, BED
54  2020 Cooperative enzymatic control of N-acyl amino acids by PM20D1 and FAAH. PM20D1
55  2020 Design and SAR Analysis of Covalent Inhibitors Driven by Hybrid QM/MM Simulations. EGFR, QM/MM
56  2020 Design, microwave-assisted synthesis, biological evaluation and molecular modeling studies of 4-phenylthiazoles as potent fatty acid amide hydrolase inhibitors. 2-AG, AEA
57  2020 Development of an In Vivo Method to Estimate Effective Drug Doses and Quantify Fatty Acid Amide Hydrolase in Rodent Brain using Positron Emission Tomography Tracer [11C]DFMC. PET
58  2020 Development of multitarget inhibitors for the treatment of pain: Design, synthesis, biological evaluation and molecular modeling studies. sEH
59  2020 Discovery of heterocyclic carbohydrazide derivatives as novel selective fatty acid amide hydrolase inhibitors: design, synthesis and anti-neuroinflammatory evaluation. ---
60  2020 Dose- and time-related effects of acute diisopropylfluorophosphate intoxication on forced swim behavior and sucrose preference in rats. ChE, MAGL, OPs
61  2020 Effect of flaxseed oil supplementation on the erythrocyte membrane fatty acid composition and endocannabinoid system modulation in patients with coronary artery disease: a double-blind randomized controlled trial. AEA, CAD, CB1, CB2, ECS, LA
62  2020 Effects of the cannabinoid receptor agonist CP-55,940 on incentive salience attribution. CB1
63  2020 Elevated fatty acid amide hydrolase in the prefrontal cortex of borderline personality disorder: a [11C]CURB positron emission tomography study. BPD, PFC
64  2020 Endocannabinoid degradation inhibitors ameliorate neuronal and synaptic alterations following traumatic brain injury. EC, MAGL, SMC, TBI
65  2020 Endocannabinoid metabolism and transport as targets to regulate intraocular pressure. IOP, MAGL
66  2020 Endocannabinoid modulating drugs improve anxiety but not the expression of conditioned fear in a rodent model of post-traumatic stress disorder. eCB, NSF, PTSD, WE
67  2020 Endocannabinoid system alterations in Alzheimer's disease: A systematic review of human studies. 2-AG, AD, AEA, ECS, MAGL, MCI, TRPV1
68  2020 Experimental Activation of Endocannabinoid System Reveals Antilipotoxic Effects on Cardiac Myocytes. Cer, DAG, ECS, SHR
69  2020 Exploration of dual fatty acid amide hydrolase and cholinesterase inhibitory potential of some 3-hydroxy-3-phenacyloxindole analogs. AChE, BuChE, ChEs
70  2020 Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen. COX
71  2020 Expression and Function of the Endocannabinoid Modulating Enzymes Fatty Acid Amide Hydrolase and N-Acylphosphatidylethanolamine-Specific Phospholipase D in Endometrial Carcinoma. AEA, EC, NAEs, NAPE-PLD, OEA, PEA
72  2020 Fatty acid amide hydrolase is lower in young cannabis users. CUs, HVs
73  2020 Fatty Acid Amide Hydrolases: An Expanded Capacity for Chemical Communication? AS, NAEs
74  2020 Fibronectin induces capacitation-associated events through the endocannabinoid system in bull sperm. AEA, FN, NO, pPKAs, pY
75  2020 Genetics of methamphetamine use disorder: A systematic review and meta-analyses of gene association studies. BDNF, GWASs
76  2020 Heteroarylureas with fused bicyclic diamine cores as inhibitors of fatty acid amide hydrolase. ---
77  2020 Heterogeneity of the Endocannabinoid System Between Cerebral Cortex and Spinal Cord Oligodendrocytes. DAGLA, ECS, Gde1, OLs, OPCs, TRPV1
78  2020 High fat diet induced obesity alters endocannabinoid and ghrelin mediated regulation of components of the endocannabinoid system in nodose ganglia. AEA, CB1, HFD, SLD, TPRV1
79  2020 High-intensity swimming exercise reduces inflammatory pain in mice by activation of the endocannabinoid system. CFA, eCB, HISE, i.p, i.pl, i.t, MAGL
80  2020 Hippocampal 2-Arachidonoyl Glycerol Signaling Regulates Time-of-Day- and Stress-Dependent Effects on Rat Short-Term Memory. 2-AG, AEA, MAGL
82  2020 Imaging Brain Fatty Acid Amide Hydrolase in Untreated Patients With Psychosis. ---
83  2020 Impacts of epidural electrical stimulation on Wnt signaling, FAAH, and BDNF following thoracic spinal cord injury in rat. BDNF, ES, SCI, Wnt3
84  2020 In Silico and In Vitro Analysis of Major Cannabis-Derived Compounds as Fatty Acid Amide Hydrolase Inhibitors. eCB
85  2020 Inhibition of Fatty Acid Amide Hydrolase (FAAH) During Adolescence and Exposure to Early Life Stress may Exacerbate Depression-like Behaviors in Male and Female Rats. BLA, CB1R, ELS, GRs, PFC
86  2020 Inhibition of fatty acid amide hydrolase by chlorpyrifos in juvenile rats results in altered exploratory and social behavior as adolescents. CPF
87  2020 Inhibition of fatty acid amide hydrolase in the CNS prevents and reverses morphine tolerance in male and female mice. NAPE-PLD
88  2020 Inhibition of fatty acid amide hydrolase prevents pathology in neurovisceral acid sphingomyelinase deficiency by rescuing defective endocannabinoid signaling. ASMD, ASMKO, eCB, NPC, SM
89  2020 Inhibition of the fatty acid amide hydrolase changes behaviors and brain catecholamines in a sex-specific manner in rats exposed to chronic unpredictable stress. CUS, IL-10, IL-6, mPFC
90  2020 Involvement of endocannabinoid system, inflammation and apoptosis in diabetes induced liver injury: Role of 5-HT3 receptor antagonist. CB1, TNF-alpha and IL-6
91  2020 Lower brain fatty acid amide hydrolase in treatment-seeking patients with alcohol use disorder: a positron emission tomography study with [C-11]CURB. AUD
92  2020 Mechanism of Diuresis and Natriuresis by Cannabinoids: Evidence for Inhibition of Na+-K+-ATPase in Mouse Kidney Thick Ascending Limb Tubules. AEA, CB1, CBRs, CR, KO, Ou, TAL
93  2020 N6-Methyladenosine Modification of Fatty Acid Amide Hydrolase Messenger RNA in Circular RNA STAG1-Regulated Astrocyte Dysfunction and Depressive-like Behaviors. ALKBH5, circSTAG1, m6A, MDD
94  2020 Organophosphate Agent Induces ADHD-Like Behaviors via Inhibition of Brain Endocannabinoid-Hydrolyzing Enzyme(s) in Adolescent Male Rats. ADHD, EOPF, MAGL, OP
95  2020 Paracetamol analogues conjugated by FAAH induce TRPV1-mediated antinociception without causing acute liver toxicity. 4-AP
96  2020 Pharmacological characterization of a novel, potent, selective, and orally active fatty acid amide hydrolase inhibitor, PKM-833 [(R)-N-(pyridazin-3-yl)-4-(7-(trifluoromethyl)chroman-4-yl)piperazine-1-carboxamide] in rats: Potential for the treatment of inflammatory pain. AEA, CCI, CFA
97  2020 Potential application of endocannabinoid system agents in neuropsychiatric and neurodegenerative diseases-focusing on FAAH/MAGL inhibitors. AD, ECS, MAGL, PD
98  2020 Preclinical pharmacological evaluation of the fatty acid amide hydrolase inhibitor BIA 10-2474. SHRSP
99  2020 Pyrrolidin-2-one linked benzofused heterocycles as novel small molecule monoacylglycerol lipase inhibitors and antinociceptive agents. GBP, hMAGL
100  2020 Racial and sex differences in the polymorphisms of the endocannabinoid receptor genes in obesity. AAs, BMI, EC, PCR