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[Related PubMed/MEDLINE]
Total Number of Papers: 199
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| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2022 |
A Link Between Methylglyoxal and Heart Failure During HIV-1 Infection. |
DD, HF, hu-mice, MG |
| 2 |
2022 |
Accumulation of acetaldehyde in aldh2.1-/- zebrafish causes increased retinal angiogenesis and impaired glucose metabolism. |
AA, Akr1a1a, Aldh3a1, G6PC, GCK, JNK, RCS |
| 3 |
2022 |
Clinical Implications of Glyoxalase1 Gene Polymorphism and Elevated Levels of the Reactive Metabolite Methylglyoxal in the Susceptibility of Type 2 Diabetes Mellitus in the Patients from Asir and Tabuk Regions of Saudi Arabia. |
MG, SNP, T2DM |
| 4 |
2022 |
Emerging Glycation-Based Therapeutics-Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors. |
BBGD, MG, tRES-HESP |
| 5 |
2022 |
Evaluation of Fructosamine 3-kinase and Glyoxalase 1 activity in normal and breast cancer tissues. |
AGEs, FN3K, MG |
| 6 |
2022 |
GLO1 Contributes to the Drug Resistance of Escherichia coli Through Inducing PER Type of Extended-Spectrum β-Lactamases. |
AMR, ELISA, ESBLs |
| 7 |
2022 |
Methylglyoxal Scavengers Attenuate Angiogenesis Dysfunction Induced by Methylglyoxal and Oxygen-Glucose Deprivation. |
AG, CAM, HBMECs, MG, NAC, OGD, RAGE, ROS |
| 8 |
2022 |
Salicylate metal-binding isosteres as fragments for metalloenzyme inhibition. |
FBDD, MBIs, MBP, MMP-3 |
| 9 |
2021 |
Accumulation of Carbonyl Proteins in the Brain of Mouse Model for Methylglyoxal Detoxification Deficits. |
AGEs, CS-SCZ, MGO |
| 10 |
2021 |
Defective Glyoxalase 1 Contributes to Pathogenic Inflammation in Cystic Fibrosis. |
CF |
| 11 |
2021 |
Dicarbonyl stress, protein glycation and the unfolded protein response. |
MG, UPR |
| 12 |
2021 |
Eugenol and its liposome-based nano carrier reduce anxiety by inhibiting glyoxylase-1 expression in mice. |
MG |
| 13 |
2021 |
Fentanyl-induced acute and conditioned behaviors in two inbred mouse lines: Potential role for Glyoxalase. |
Sapcd1 |
| 14 |
2021 |
Genetic and Pharmacological Manipulations of Glyoxalase 1 Mediate Ethanol Withdrawal Seizure Susceptibility in Mice. |
CNS, FVB, HICs |
| 15 |
2021 |
GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival. |
ALDH1, CSCs, PKC, TNBC |
| 16 |
2021 |
Glyoxal-Lysine Dimer, an Advanced Glycation End Product, Induces Oxidative Damage and Inflammatory Response by Interacting with RAGE. |
AGE, GO, GOLD, MAPK, Nrf2, ROS |
| 17 |
2021 |
Glyoxalase 1 and protein kinase Clamda as potential therapeutic targets for late-stage breast cancer. |
PKClamda |
| 18 |
2021 |
Glyoxalase 1 Confers Susceptibility to Schizophrenia: From Genetic Variants to Phenotypes of Neural Function. |
eQTL, FDR, fMRI, mRNA, PCR, ROC |
| 19 |
2021 |
Glyoxalase 1 Expression as a Novel Diagnostic Marker of High-Grade Prostatic Intraepithelial Neoplasia in Prostate Cancer. |
HGPIN, MG, PCa |
| 20 |
2021 |
Glyoxalase-1-Dependent Methylglyoxal Depletion Sustains PD-L1 Expression in Metastatic Prostate Cancer Cells: A Novel Mechanism in Cancer Immunosurveillance Escape and a Potential Novel Target to Overcome PD-L1 Blockade Resistance. |
AGEs, MG, mPCa |
| 21 |
2021 |
Hesperetin ameliorates diabetes-associated anxiety and depression-like behaviors in rats via activating Nrf2/ARE pathway. |
gamma-GCS |
| 22 |
2021 |
High-sucrose diets contribute to brain angiopathy with impaired glucose uptake and psychosis-related higher brain dysfunctions in mice. |
--- |
| 23 |
2021 |
Methylglyoxal-Dependent Glycative Stress Is Prevented by the Natural Antioxidant Oleuropein in Human Dental Pulp Stem Cells through Nrf2/Glo1 Pathway. |
DPSCs, MG, OP |
| 24 |
2021 |
Phenethyl isothiocyanate attenuates diabetic nephropathy via modulation of glycative/oxidative/inflammatory signaling in diabetic rats. |
AGEs, DN, gamma-GCS, HO-1, Nrf2, PEITC |
| 25 |
2021 |
Polydatin protects Schwann cells from methylglyoxal induced cytotoxicity and promotes crushed sciatic nerves regeneration of diabetic rats. |
PD, RAGE |
| 26 |
2021 |
Polymorphisms in Glyoxalase I Gene Are Not Associated with Glyoxalase I Expression in Whole Blood or Markers of Methylglyoxal Stress: The CODAM Study. |
AGEs, MGO |
| 27 |
2021 |
Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds. |
AGEs, IL-4, LPS, MGO, PM, T2DM |
| 28 |
2021 |
Role of glyoxalase 1 in methylglyoxal detoxification-the broad player of psychiatric disorders. |
MG |
| 29 |
2021 |
Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Spliceosome. |
HR, MDR, MG |
| 30 |
2021 |
The Glyoxalase System in Age-Related Diseases: Nutritional Intervention as Anti-Ageing Strategy. |
AGEs |
| 31 |
2021 |
TNF-ɑ Induces Methylglyoxal Accumulation in Lumbar Herniated Disc of Patients With Radicular Pain. |
LDH, MG, NP |
| 32 |
2021 |
γ-Glutamyl-Transpeptidase-Resistant Glutathione Analog Attenuates Progression of Alzheimer's Disease-like Pathology and Neurodegeneration in a Mouse Model. |
AD, GGT, LC |
| 33 |
2020 |
Adeno-Associated Viral Transfer of Glyoxalase-1 Blunts Carbonyl and Oxidative Stresses in Hearts of Type 1 Diabetic Rats. |
DC, MG, T1DM |
| 34 |
2020 |
Association between carbonyl stress markers and the risk of acute coronary syndrome in patients with type 2 diabetes mellitus-A pilot study. |
ACS, CK-MB, CK-T, CML, GAPDH, MG, MG-H1, T2DM |
| 35 |
2020 |
Associations of dicarbonyl stress with complement activation: the CODAM study. |
3-DG, CODAM, GO, MGO, sC5b-9 |
| 36 |
2020 |
Bombax ceiba (Linn.) calyxes ameliorate methylglyoxal-induced oxidative stress via modulation of RAGE expression: identification of active phytometabolites by GC-MS analysis. |
AGEs, BCCE, GC-MS, MG, NOX, ROS |
| 37 |
2020 |
Chebulic Acid Prevents Methylglyoxal-Induced Mitochondrial Dysfunction in INS-1 Pancreatic beta-Cells. |
ATP, CA, GSIS, MG, MMP, ROS |
| 38 |
2020 |
Chemoproteomic Profiling of a Pharmacophore-Focused Chemical Library. |
--- |
| 39 |
2020 |
Classically activated mouse macrophages produce methylglyoxal that induces a TLR4- and RAGE-independent proinflammatory response. |
MG, RAGE |
| 40 |
2020 |
Cyanidin Attenuates Methylglyoxal-Induced Oxidative Stress and Apoptosis in INS-1 Pancreatic beta-Cells by Increasing Glyoxalase-1 Activity. |
AGEs, MG, ROS |
| 41 |
2020 |
Discovery of GLO1 New Related Genes and Pathways by RNA-Seq on A2E-Stressed Retinal Epithelial Cells Could Improve Knowledge on Retinitis Pigmentosa. |
MG, ROS |
| 42 |
2020 |
Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry. |
AA, TPI |
| 43 |
2020 |
Glyoxalase 1 Inhibitor Alleviates Autism-like Phenotype in a Prenatal Valproic Acid-Induced Mouse Model. |
ASD, VPA |
| 44 |
2020 |
Glyoxalase system: A systematic review of its biological activity, related-diseases, screening methods and small molecule regulators. |
AGEs, Glo2, MG |
| 45 |
2020 |
LncRNA OIP5-AS1 Promotes Breast Cancer Progression by Regulating miR-216a-5p/GLO1. |
OIP5-AS1 |
| 46 |
2020 |
Long-term intake of the reactive metabolite methylglyoxal is not toxic in mice. |
AGEs, MG, RAGE |
| 47 |
2020 |
Morroniside attenuates high glucose-induced BMSC dysfunction by regulating the Glo1/AGE/RAGE axis. |
ALP, BMSC, HG, RAGE, T1DM, WB |
| 48 |
2020 |
Pentoxifylline mitigates renal glycoxidative stress in obese mice by inhibiting AGE/RAGE signaling and increasing glyoxalase levels. |
AGEs, RAGE |
| 49 |
2020 |
Phosphorylation of T107 by CamKIIdelta Regulates the Detoxification Efficiency and Proteomic Integrity of Glyoxalase 1. |
CamKIIdelta, MG |
| 50 |
2020 |
Psoralea corylifolia L. Seed Extract Attenuates Methylglyoxal-Induced Insulin Resistance by Inhibition of Advanced Glycation End Product Formation. |
AGEs, MGO, PCS |
| 51 |
2020 |
Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity. |
EMT |
| 52 |
2020 |
Resveratrol, Curcumin and Piperine Alter Human Glyoxalase 1 in MCF-7 Breast Cancer Cells. |
DeltaPsim, R-C-P |
| 53 |
2020 |
Spectrophotometric Method for Determining Glyoxalase 1 Activity in Cerebral Cavernous Malformation (CCM) Disease. |
CCM, HBMEC, MEF, MG, PBS, SLG |
| 54 |
2020 |
The Antidepressant-Like Effects of Hesperidin in Streptozotocin-Induced Diabetic Rats by Activating Nrf2/ARE/Glyoxalase 1 Pathway. |
HG, Nrf2 |
| 55 |
2019 |
A novel compound AB-38b improves diabetes-associated cognitive decline in mice via activation of Nrf2/ARE pathway. |
AGEs, DACD, Nrf2 |
| 56 |
2019 |
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal. |
HAECs, HK2, MG, tRES-HESP, UPR |
| 57 |
2019 |
Ameliorating Methylglyoxal-Induced Progenitor Cell Dysfunction for Tissue Repair in Diabetes. |
BMPC, IRE1alpha, MGO, PC |
| 58 |
2019 |
Effect of dietary vitamin E on oxidative stress-related gene-mediated differences in anxiety-like behavior in inbred strains of mice. |
--- |
| 59 |
2019 |
Gene doubling increases glyoxalase 1 expression in RAGE knockout mice. |
RAGE, RAGE-KO |
| 60 |
2019 |
Glycine increases glyoxalase-1 function by promoting nuclear factor erythroid 2-related factor 2 translocation into the nucleus of kidney cells of streptozotocin-induced diabetic rats. |
mRNA, Nrf2 |
| 61 |
2019 |
Glycine Suppresses AGE/RAGE Signaling Pathway and Subsequent Oxidative Stress by Restoring Glo1 Function in the Aorta of Diabetic Rats and in HUVECs. |
AGEs, HUVECs, MG, RAGE |
| 62 |
2019 |
Glyoxalase 1 Prevents Chronic Hyperglycemia Induced Heart-Explant Derived Cell Dysfunction. |
EDC |
| 63 |
2019 |
Hesperetin ameliorates diabetic nephropathy in rats by activating Nrf2/ARE/glyoxalase 1 pathway. |
AGEs, DN, Nrf2 |
| 64 |
2019 |
Imaging Tumorous Methylglyoxal by an Activatable Near-Infrared Fluorescent Probe for Monitoring Glyoxalase 1 Activity. |
MGO, NIR |
| 65 |
2019 |
Indole-4-carboxaldehyde Isolated from Seaweed, Sargassum thunbergii, Attenuates Methylglyoxal-Induced Hepatic Inflammation. |
MGO, NF-kappaB, RAGE, ST-I4C, TNF |
| 66 |
2019 |
Investigation of betaine as a novel psychotherapeutic for schizophrenia. |
MAP, QTL |
| 67 |
2019 |
Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor. |
--- |
| 68 |
2019 |
Methylglyoxal Acts as a Tumor-Promoting Factor in Anaplastic Thyroid Cancer. |
AG, AGEs, ATC, MG, PTC |
| 69 |
2019 |
Methylglyoxal triggers human aortic endothelial cell dysfunction via modulation of the KATP/MAPK pathway. |
AGEs, ERK, HAECs, JNK, MGO |
| 70 |
2019 |
Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer. |
AGEs, ECM, MAPK, MG |
| 71 |
2019 |
Reduction of glyoxalase 1 (GLO1) aggravates cerebrovascular remodeling via promoting the proliferation of basilar smooth muscle cells in hypertension. |
Ang II, BASMC |
| 72 |
2019 |
SIRT1 participates in the response to methylglyoxal-dependent glycative stress in mouse oocytes and ovary. |
AGEs, Glo2, MG |
| 73 |
2019 |
Tanshinone IIa protects retinal endothelial cells against mitochondrial fission induced by methylglyoxal through glyoxalase 1. |
AGEs, BRECs, MGO, NO, TanIIa |
| 74 |
2019 |
The attenuating effects of pyridoxamine on adipocyte hypertrophy and inflammation differ by adipocyte location. |
HFD, NFD, RAGE |
| 75 |
2019 |
Therapeutic Potential of Lespedeza bicolor to Prevent Methylglyoxal-Induced Glucotoxicity in Familiar Diabetic Nephropathy. |
AGEs, LB, MGO, Nrf2, RAGE, ROS |
| 76 |
2018 |
Advanced glycation end products in the pathogenesis of chronic kidney disease. |
AGEs, CKD, CML, DKD, MG |
| 77 |
2018 |
Age-related alteration in the distribution of methylglyoxal and its metabolic enzymes in the mouse brain. |
AGEs, AR, MG |
| 78 |
2018 |
Biophysical and biochemical studies on glycoxidatively modified human low density lipoprotein. |
LDL, MGO, ROS, T2DM |
| 79 |
2018 |
Data in support of sustained upregulation of adaptive redox homeostasis mechanisms caused by KRIT1 loss-of-function. |
HBMEC |
| 80 |
2018 |
Deleterious Effect of Advanced CKD on Glyoxalase System Activity not Limited to Diabetes Aetiology. |
--- |
| 81 |
2018 |
Dicarbonyl Stress and Glyoxalase-1 in Skeletal Muscle: Implications for Insulin Resistance and Type 2 Diabetes. |
--- |
| 82 |
2018 |
Effect of metformin treatment in patients with type 2 diabetes with respect to glyoxalase 1 activity in atherosclerotic lesions. |
MG |
| 83 |
2018 |
Enhancement of glyoxalase 1, a polyfunctional defense enzyme, by quercetin in the brain in streptozotocin-induced diabetic rats. |
AGEs, MG, RAGE |
| 84 |
2018 |
Eucommia ulmoides Ameliorates Glucotoxicity by Suppressing Advanced Glycation End-Products in Diabetic Mice Kidney. |
AGEs, MGO, Nrf2, PAS, RAGE, STZ |
| 85 |
2018 |
Fabrication of an electrochemical biosensor with ZnO nanoflakes interface for methylglyoxal quantification in food samples. |
MG, ZnO |
| 86 |
2018 |
GLO1 gene polymorphisms and their association with retinitis pigmentosa: a case-control study in a Sicilian population. |
MGO, RP, SNPs |
| 87 |
2018 |
Glyoxalase 1 (GLO1) Inhibition or Genetic Overexpression Does Not Alter Ethanol's Locomotor Effects: Implications for GLO1 as a Therapeutic Target in Alcohol Use Disorders. |
EtOH, MG |
| 88 |
2018 |
Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells. |
--- |
| 89 |
2018 |
Glyoxalase 1 sustains the metastatic phenotype of prostate cancer cells via EMT control. |
AGEs, AP, EMT, MG, PCa |
| 90 |
2018 |
Glyoxalases in Urological Malignancies. |
Glo2, MG, PCa |
| 91 |
2018 |
Gromwell (Lithospermum erythrorhizon) root extract protects against glycation and related inflammatory and oxidative stress while offering UV absorption capability. |
AGE, NF-kappaB, Nrf2, UV |
| 92 |
2018 |
Inhibition of GLO1 in Glioblastoma Multiforme Increases DNA-AGEs, Stimulates RAGE Expression, and Inhibits Brain Tumor Growth in Orthotopic Mouse Models. |
AGEs, GBM, MG, RAGE, shRNA |
| 93 |
2018 |
Inhibition of Glyoxalase 1 reduces alcohol self-administration in dependent and nondependent rats. |
--- |
| 94 |
2018 |
Intermittent hypoxia, brain glyoxalase-1 and glutathione reductase-1, and anxiety-like behavior in mice. |
GR1 |
| 95 |
2018 |
Isoferulic acid attenuates methylglyoxal-induced apoptosis in INS-1 rat pancreatic beta-cell through mitochondrial survival pathways and increasing glyoxalase-1 activity. |
AGEs, GSIS, IFA, MG, ROS, UCP2 |
| 96 |
2018 |
Methylglyoxal accumulation de-regulates HoxA5 expression, thereby impairing angiogenesis in glyoxalase 1 knock-down mouse aortic endothelial cells. |
DM, MCECs, MGO |
| 97 |
2018 |
miR-137 inhibits melanoma cell proliferation through downregulation of GLO1. |
MG, miRNAs, qRT-PCR |
| 98 |
2018 |
Neuronal damage and shortening of lifespan in C. elegans by peritoneal dialysis fluid: Protection by glyoxalase-1. |
AGEs, C. elegans, GDPs, PD |
| 99 |
2018 |
Neuroprotection of quercetin on central neurons against chronic high glucose through enhancement of Nrf2/ARE/glyoxalase-1 pathway mediated by phosphorylation regulation. |
gamma-GCS, HG |
| 100 |
2018 |
Nicotine induces apoptosis in human osteoblasts via a novel mechanism driven by H2O2 and entailing Glyoxalase 1-dependent MG-H1 accumulation leading to TG2-mediated NF-kB desensitization: Implication for smokers-related osteoporosis. |
AGEs, MG, RAGE, TG2 |
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