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■ Abbreviation / Long Form : HBMEC / human brain microvascular endothelial cells

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Total Number of Papers: 294
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Abbreviation:   HBMEC  (>> Co-occurring Abbreviation)
Long Form:   human brain microvascular endothelial cells
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No. Year Title Co-occurring Abbreviation
2021 Central Nervous System-Infecting Pathogens Escherichia coli and Cryptococcus neoformans Exploit the Host Pdlim2 for Intracellular Traversal and Exocytosis in the Blood-Brain Barrier. CNS
2021 Cronobacter sakazakii ATCC 29544 Translocated Human Brain Microvascular Endothelial Cells via Endocytosis, Apoptosis Induction, and Disruption of Tight Junction. C. sakazakii
2021 FGF20 Protected Against BBB Disruption After Traumatic Brain Injury by Upregulating Junction Protein Expression and Inhibiting the Inflammatory Response. AJs, BBB, FGF20, rhFGF20, TBI, TEER, TJs
2021 Ifenprodil Improves Long-Term Neurologic Deficits Through Antagonizing Glutamate-Induced Excitotoxicity After Experimental Subarachnoid Hemorrhage. BBB, CSF, NMDA
2021 Recombinant Annexin A2 Administration Improves Neurological Outcomes After Traumatic Brain Injury in Mice. BBB, CCI, rA2, TBI
2020 Atorvastatin disrupts primary human brain microvascular endothelial cell functions via prenylation-dependent mitochondrial inhibition and oxidative stress. BBB, VEGF
2020 Brucella abortus-Stimulated Platelets Activate Brain Microvascular Endothelial Cells Increasing Cell Transmigration through the Erk1/2 Pathway. BBB
2020 Effect of Zhenxin Xingshui Yizhi Fang on Aβ25-35 induced expression of related transporters in HBMEC cell model. AD, LRP1, XSF
2020 Ezrin is essential for the entry of Japanese encephalitis virus into the human brain microvascular endothelial cells. JEV
10  2020 Glioblastoma Factors Increase the Migration of Human Brain Endothelial Cells In Vitro by Increasing MMP-9/CXCR4 Levels. GB, GB-CM
11  2020 Insight into the proteomic profiling of exosomes secreted by human OM-MSCs reveals a new potential therapy. APOE, EGFR, HSP90AB1, MSCs, Notch2, OM-MSCs
12  2020 Spectrophotometric Method for Determining Glyoxalase 1 Activity in Cerebral Cavernous Malformation (CCM) Disease. CCM, GLO1, MEF, MG, PBS, SLG
13  2020 Testing the effect of PAR1 inhibitors on Plasmodium falciparum-induced loss of endothelial cell barrier function. APC, EPCR, IE, PAR1, PfEMP1, TEER
14  2020 [Effect of baicalin on inflammatory response and TLR4/NF-kappaB signaling pathway of human brain microvascular endothelial cell after hypoxia-reoxygenation injury]. IL-6, MYD88, OGD, p-NF-kappaB, TLR4, TNF-alpha
15  2020 [Effect of Sijunzi Decoction on regulation of Abeta-related proteins across blood-brain barrier]. AD, RT-qPCR
16  2019 A streptococcal Fic domain-containing protein disrupts blood-brain barrier integrity by activating moesin in endothelial cells. BBB, SEZ
17  2019 HDAC3 inhibition prevents blood-brain barrier permeability through Nrf2 activation in type 2 diabetes male mice. BBB, HDAC3, HG-IL1beta, T2DM
18  2019 In vitro expression of vital virulent genes of clinical and environmental isolates of Cryptococcus neoformans/gattii in endothelial cells of human blood-brain barrier. ---
19  2019 Inhibitor discovery for the E. coli meningitis virulence factor IbeA from homology modeling and virtual screening. E. coli
20  2019 Interplay of Plasmodium falciparum and thrombin in brain endothelial barrier disruption. CM, IE, TNF-alpha
21  2019 Long noncoding RNA XIST participates hypoxia-induced angiogenesis in human brain microvascular endothelial cells through regulating miR-485/SOX7 axis. lncRNAs, SOX7, VEGF, XIST
22  2019 More than just inflammation: Ureaplasma species induce apoptosis in human brain microvascular endothelial cells. Up3, Uu8
23  2019 Neisseria meningitidis Type IV Pili Trigger Ca2+-Dependent Lysosomal Trafficking of the Acid Sphingomyelinase To Enhance Surface Ceramide Levels. ASM, CRPs
24  2019 Selective mGluR1 Negative Allosteric Modulator Reduces Blood-Brain Barrier Permeability and Cerebral Edema After Experimental Subarachnoid Hemorrhage. BBB, CSF, EBI, mGluR1, SAH, VASP
25  2019 Sex differences in the expression of cell adhesion molecules on microvesicles derived from cultured human brain microvascular endothelial cells treated with inflammatory and thrombotic stimuli. MV, Thr
26  2019 UHPLC-QTOF/MS-based metabolomics investigation for the protective mechanism of Danshen in Alzheimer's disease cell model induced by Abeta1-42. AD, PLS-DA, TCM
27  2019 Ureaplasma species modulate cell adhesion molecules and growth factors in human brain microvascular endothelial cells. G-CSF, LPS, VEGF
28  2019 Ureaplasma Species Modulate Cytokine and Chemokine Responses in Human Brain Microvascular Endothelial Cells. IL, LPS, MCP
29  2019 Vitexin protects against ischemia/reperfusion-induced brain endothelial permeability. BBB, I/R, LDH, MMP
30  2018 Brucella abortus Traverses Brain Microvascular Endothelial Cells Using Infected Monocytes as a Trojan Horse. BBB, CNS
31  2018 Data in support of sustained upregulation of adaptive redox homeostasis mechanisms caused by KRIT1 loss-of-function. GLO1
32  2018 High Circulatory Phosphate Level Is Associated with Cerebral Small-Vessel Diseases. CSVDs, WMHs
33  2018 Nipah Virus Infection of Immature Dendritic Cells Increases Its Transendothelial Migration Across Human Brain Microvascular Endothelial Cells. BBB, CNS, iDC, NiV, pMO
34  2018 Novel insights into neuroinflammation: bacterial lipopolysaccharide, tumor necrosis factor alpha, and Ureaplasma species differentially modulate atypical chemokine receptor 3 responses in human brain microvascular endothelial cells. LPS, TNF-alpha, Up3, Uu8
35  2018 Recombinant FGF21 Protects Against Blood-Brain Barrier Leakage Through Nrf2 Upregulation in Type 2 Diabetes Mice. BBB, FGF21, FGFR1, HG-IL1beta, Keap1, Nrf2, rFGF21, T2D
36  2018 Report: Effect of macrophage alone or primed with cytokines on Balamuthia mandrillaris interactions with human brain microvascular endothelial cells in vitro. BAE, BBB, CNS
37  2018 Soluble CD40 ligand disrupts the blood-brain barrier and exacerbates inflammation in experimental autoimmune encephalomyelitis. BBB, EAE, MS, sCD40L
38  2018 The Meningococcal Cysteine Transport System Plays a Crucial Role in Neisseria meningitidis Survival in Human Brain Microvascular Endothelial Cells. cbp, CTS, IMD
39  2018 Transport of enniatin B and enniatin B1 across the blood-brain barrier and hints for neurotoxic effects in cerebral cells. CCK-8, LDH, PBCEC
40  2017 Analysis of Lymphocyte Extravasation Using an In Vitro Model of the Human Blood-brain Barrier. CNS, TEER
41  2017 bFGF Protects Against Oxygen Glucose Deprivation/Reoxygenation-Induced Endothelial Monolayer Permeability via S1PR1-Dependent Mechanisms. BBB, bFGF, FGFR1, OGD/R, S1PR1, TEER
42  2017 Comparative and Experimental Studies on the Genes Altered by Chronic Hypoxia in Human Brain Microendothelial Cells. HIF1A
43  2017 Comparison of the inflammatory response of brain microvascular and peripheral endothelial cells following infection with Neisseria meningitidis. CC, IL-6, MCP-1
44  2017 Differential Mechanisms of Inflammation and Endothelial Dysfunction by HIV-1 Subtype-B and Recombinant CRF02_AG Tat Proteins on Human Brain Microvascular Endothelial Cells: Implications for Viral Neuropathogenesis. AP-1, BBB, HAND, IRAK, JNK, MKK, NF-kappaB, Tat.B, TEER
45  2017 Host Cell Vimentin Restrains Toxoplasma gondii Invasion and Phosphorylation of Vimentin is Partially Regulated by Interaction with TgROP18. ---
46  2017 Impact of commercial cigarette smoke condensate on brain tissue co-cultured with astrocytes and blood-brain barrier endothelial cells. CCSC, HBMEC-T98G co-culture, ROS, TEER, U-373 MG-T98G co-culture
47  2017 Inhibiting endoplasmic reticulum stress by lithium chloride contributes to the integrity of blood-spinal cord barrier and functional recovery after spinal cord injury. BSCB, ER, LiCl, SCI, TG
48  2017 IQGAP1 Mediates Hcp1-Promoted Escherichia coli Meningitis by Stimulating the MAPK Pathway. Hcp1, IQGAP1, MS
49  2017 Microvesicles Derived from Inflammation-Challenged Endothelial Cells Modulate Vascular Smooth Muscle Cell Functions. EMV, HBVSMC, MV, SD, TNF-alpha
50  2017 Outbreak Caused by Escherichia coli O18: K1: H7 Sequence Type 95 in a Neonatal Intensive Care Unit in Barcelona, Spain. PAI
51  2017 Tetrahydroxy stilbene glucoside ameliorates H2O2-induced human brain microvascular endothelial cell dysfunction invitro by inhibiting oxidative stress and inflammatory responses. IL, TSG
52  2017 The role of heme-oxygenase-1 in pathogenesis of cerebral malaria in the co-culture model of human brain microvascular endothelial cell and ITG Plasmodium falciparum-infected red blood cells. HO-1
53  2017 Toll-Like Receptor-3 Mediates HIV-1-Induced Interleukin-6 Expression in the Human Brain Endothelium via TAK1 and JNK Pathways: Implications for Viral Neuropathogenesis. BBB, HAND, IRAK, TLRs
54  2017 Vacuolation Activity and Intracellular Trafficking of ArtB, the Binding Subunit of an AB5 Toxin Produced by Salmonella enterica Serovar Typhi. CHO, ER
55  2016 Anthelmintic drug ivermectin inhibits angiogenesis, growth and survival of glioblastoma through inducing mitochondrial dysfunction and oxidative stress. ---
56  2016 Cystatin C Shifts APP Processing from Amyloid-beta Production towards Non-Amyloidgenic Pathway in Brain Endothelial Cells. AD, APP, CysC
57  2016 EGFR transactivation contributes to neuroinflammation in Streptococcus suis meningitis. AREG, EGFR, EREG, SS2
58  2016 Glial Cell-Elicited Activation of Brain Microvasculature in Response to Brucella abortus Infection Requires ASC Inflammasome-Dependent IL-1beta Production. CS, ICAM-1
59  2016 Identification of CiaR Regulated Genes That Promote Group B Streptococcal Virulence and Interaction with Brain Endothelial Cells. BBB, CNS, GBS
60  2016 MicroRNA-125a-5p alleviates the deleterious effects of ox-LDL on multiple functions of human brain microvessel endothelial cells. EGFR, eNOS, ERK, miR-125a-5p, NO, oxLDL, p38 MAPK, PI3K, ROS
61  2016 Phenylbutyrate prevents disruption of blood-spinal cord barrier by inhibiting endoplasmic reticulum stress after spinal cord injury. BSCB, ER, PBA, SCI
62  2016 [Protective effects of three phenylallyl compounds from Guizhi decoction ox-LDL-induced oxidative stress injury of human brain microvascular endothelial cells]. DMSO, LSCM, qRT-PCR, ROS
63  2015 A Serine-Threonine Kinase (StkP) Regulates Expression of the Pneumococcal Pilus and Modulates Bacterial Adherence to Human Epithelial and Endothelial Cells In Vitro. StkP
64  2015 Astaxanthin induces angiogenesis through Wnt/beta-catenin signaling pathway. RASMC
65  2015 Autophagy protects human brain microvascular endothelial cells against methylglyoxal-induced injuries, reproducible in a cerebral ischemic model in diabetic rats. 3-MA, AC, CQ, ECs, MGO
66  2015 Cannabidiol protects an in vitro model of the blood-brain barrier from oxygen-glucose deprivation via PPARγ and 5-HT1A receptors. BBB, CBD, OGD
67  2015 Cronobacter sakazakii clinical isolates overcome host barriers and evade the immune response. cpa, NEC
68  2015 Cytotoxic effects of aflatoxin B1 on human brain microvascular endothelial cells of the blood-brain barrier. HUVEC
69  2015 Exogenous arachidonic acid mediates permeability of human brain microvessel endothelial cells through prostaglandin E2 activation of EP3 and EP4 receptors. ARA, HBMECs, PGE2
70  2015 Identification of target antigens of antiendothelial cell antibodies against human brain microvascular endothelial cells in healthy subjects. AECAs
71  2015 Multiple Functions of Glutamate Uptake via Meningococcal GltT-GltM L-Glutamate ABC Transporter in Neisseria meningitidis Internalization into Human Brain Microvascular Endothelial Cells. AM, FBS
72  2015 Oxidative Stress Induced by Cigarette Smoke Extracts in Human Brain Cells (T98G) and Human Brain Microvascular Endothelial Cells (HBMEC) in Mono- and Co-Culture. CSC, CSE, ROS
73  2015 Probucol Protects Against Asymmetric Dimethylarginine-Induced Apoptosis in the Cultured Human Brain Microvascular Endothelial Cells. ADMA, BDNF, JNK, MDA, ROS
74  2015 Proteomic analysis of human brain microvascular endothelial cells reveals differential protein expression in response to enterovirus 71 infection. ---
75  2015 Tanshinone IIA protects against methylglyoxal-induced injury in human brain microvascular endothelial cells. MGO, ROS, TBARS
76  2015 The protective role of isorhamnetin on human brain microvascular endothelial cells from cytotoxicity induced by methylglyoxal and oxygen-glucose deprivation. AGEs, MGO, MGO, NF-kappaB, OGD
77  2015 Visfatin Mediates SCLC Cells Migration across Brain Endothelial Cells through Upregulation of CCL2. BBB, CCL2, SCLC
78  2015 [Role of TRPV4 channels in regulation of eNOS expression in brain microvascular endothelial cells under the condition of mechanical stretch]. TRPs
79  2014 Adverse effects of antipsychotics on micro-vascular endothelial cells of the human blood-brain barrier. APs, BBB, CLP, CLZ, HAL, RIS
80  2014 Copper transport mediated by nanocarrier systems in a blood-brain barrier in vitro model. AD, BBB, EBA, MRE-GFP, NP, PSe
81  2014 Curculigoside A induces angiogenesis through VCAM-1/Egr-3/CREB/VEGF signaling pathway. CREB, EGR3, HMBEC, VCAM-1, VEGF, VEGFR2
82  2014 Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction. BBB, CRF, MMP, Tat.B
83  2014 Hexane extracts of Polygonum multiflorum improve tissue and functional outcome following focal cerebral ischemia in mice. eNOS KO
84  2014 HIV-1 induces cytoskeletal alterations and Rac1 activation during monocyte-blood-brain barrier interactions: modulatory role of CCR5. ---
85  2014 Hyperglycaemia promotes human brain microvascular endothelial cell apoptosis via induction of protein kinase C-ßI and prooxidant enzyme NADPH oxidase. PKC
86  2014 Identification of a group B streptococcal fibronectin binding protein, SfbA, that contributes to invasion of brain endothelium and development of meningitis. BBB, GBS, SfbA, WT
87  2014 Identification of minimum carbohydrate moiety in N-glycosylation sites of brain endothelial cell glycoprotein 96 for interaction with Escherichia coli K1 outer membrane protein A. E. coli K1, OmpA
88  2014 In vitro assessment of cytokines interactions with Balamuthia mandrillaris using human brain microvascular endothelial cells. BAE, BBB, LPS
89  2014 In vitro inhibition of protease-activated receptors 1, 2 and 4 demonstrates that these receptors are not involved in an Acanthamoeba castellanii keratitis isolate-mediated disruption of the human brain microvascular endothelial cells. ---
90  2014 Marinobufagenin regulates permeability and gene expression of brain endothelial cells. MBG
91  2014 MIP-1alpha enhances Jurkat cell transendothelial migration by up-regulating endothelial adhesion molecules VCAM-1 and ICAM-1. MIP-1alpha, T-ALL
92  2014 Platelet endothelial cell adhesion molecule-1, a putative receptor for the adhesion of Streptococcus pneumoniae to the vascular endothelium of the blood-brain barrier. ---
93  2014 The surface protease ompT serves as Escherichia coli K1 adhesin in binding to human brain micro vascular endothelial cells. E. coli
94  2014 VEGF increases paracellular permeability in brain endothelial cells via upregulation of EphA2. TEER, VEGF
95  2014 Venlafaxine protects methylglyoxal-induced apoptosis in the cultured human brain microvascular endothelial cells. MGO
96  2014 Zyxin modulates the transmigration of Haemophilus influenzae to the central nervous system. BBB, CBO, IL, LPS, TNF
97  2014 [MIP-1alpha promotes the migration ability of Jurkat cell through human brain microvascular endothelial cell monolayer]. CNS, T-ALL
98  2013 Cornin induces angiogenesis through PI3K-Akt-eNOS-VEGF signaling pathway. eNOS, PI3K, VEGF
99  2013 CXCL1 contributes to β-amyloid-induced transendothelial migration of monocytes in Alzheimer's disease. AD, CXCR2
100  2013 Dysfunction of annexin A2 contributes to hyperglycaemia-induced loss of human endothelial cell surface fibrinolytic activity. PAI-1, rA2, tPA