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■ Abbreviation / Long Form : HKa / high molecular weight kininogen

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Total Number of Papers: 30
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Abbreviation:   HKa  (>> Co-occurring Abbreviation)
Long Form:   high molecular weight kininogen
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No. Year Title Co-occurring Abbreviation
2021 HAE patient self-sampling for biomarker establishment. C1-INH, DBS, HAE, HAEKA
2016 Novel role for p56/Lck in regulation of endothelial cell survival and angiogenesis. si
2015 Cleaved high-molecular-weight kininogen inhibits neointima formation following vascular injury. EGFP, SMC
2012 Ferritin blocks inhibitory effects of two-chain high molecular weight kininogen (HKa) on adhesion and survival signaling in endothelial cells. HK
2011 Cleaved high-molecular-weight kininogen accelerates the onset of endothelial progenitor cell senescence by induction of reactive oxygen species. EPCs, ROS
2009 Cleaved high molecular weight kininogen inhibits tube formation of endothelial progenitor cells via suppression of matrix metalloproteinase 2. EPCs, KKS, MMP-2, VEGF
2009 Cleaved high-molecular-weight kininogen and its domain 5 inhibit migration and invasion of human prostate cancer cells through the epidermal growth factor receptor pathway. bFGF, EGFR, ERK, uPAR
2009 Human tropomyosin isoforms in the regulation of cytoskeleton functions. ---
2009 Upregulation of tissue factor in monocytes by cleaved high molecular weight kininogen is dependent on TNF-alpha and IL-1beta. ---
10  2008 The inhibitory effect of HKa in endothelial cell tube formation is mediated by disrupting the uPA-uPAR complex and inhibiting its signaling and internalization. uPA
11  2007 Kininostatin associates with membrane rafts and inhibits alpha(v)beta3 integrin activation in human umbilical vein endothelial cells. ECs
12  2007 The inhibition of tube formation in a collagen-fibrinogen, three-dimensional gel by cleaved kininogen (HKa) and HK domain 5 (D5) is dependent on Src family kinases. Csk
13  2006 Endothelial-cell apoptosis induced by cleaved high-molecular-weight kininogen (HKa) is matrix dependent and requires the generation of reactive oxygen species. BK, HK
14  2005 Domain 5 of cleaved high molecular weight kininogen inhibits endothelial cell migration through Akt. BPAE, S1P, VEGF
15  2005 Inhibition of angiogenesis by cleaved high molecular weight kininogen (HKa) and HKa domain 5. BK, HK, HPRG
16  2004 Extracellular tropomyosin: a novel common pathway target for anti-angiogenic therapy. HPRG
17  2004 The contact system and angiogenesis: potential for therapeutic control of malignancy. CAM, HK
18  2004 Urokinase-type plasminogen activator receptor is involved in mediating the apoptotic effect of cleaved high molecular weight kininogen in human endothelial cells. ECM, uPAR
19  2003 Apoptotic effect of cleaved high molecular weight kininogen is regulated by extracellular matrix proteins. ECM, FAK, FN, Gel
20  2003 Induction of apoptosis in vascular cells by plasminogen activator inhibitor-1 and high molecular weight kininogen correlates with their anti-adhesive properties. HUVEC, PAI-1, VSMC
21  2003 Upregulation of Cdc2 and cyclin A during apoptosis of endothelial cells induced by cleaved high-molecular-weight kininogen. ---
22  2002 A novel antithrombotic role for high molecular weight kininogen as inhibitor of plasminogen activator inhibitor-1 function. PAI-1, VN
23  2002 Inhibition of angiogenesis by two-chain high molecular weight kininogen (HKa) and kininogen-derived polypeptides. CAM, HKa D5
24  2002 Inhibition of platelet adhesion and aggregation by a defined region (Gly-486-Lys-502) of high molecular weight kininogen. HK, IIb, IIb, IIb, VN
25  2002 The antiangiogenic activity of cleaved high molecular weight kininogen is mediated through binding to endothelial cell tropomyosin. ---
26  2001 Regulation of leukocyte recruitment by polypeptides derived from high molecular weight kininogen. HK, uPAR
27  2000 Different mechanisms define the antiadhesive function of high molecular weight kininogen in integrin- and urokinase receptor-dependent interactions. GST, HK, uPAR, VN
28  2000 Two-chain high molecular weight kininogen induces endothelial cell apoptosis and inhibits angiogenesis: partial activity within domain 5. HK
29  1994 Platelet thrombospondin interactions with human high and low molecular weight kininogens. HC, LC, mAb
30  1992 Inhibition of cell adhesion by high molecular weight kininogen. HK