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■ Abbreviation / Long Form : HMGB1 / high mobility group box chromosomal protein 1

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Total Number of Papers: 107
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Abbreviation:   HMGB1  (>> Co-occurring Abbreviation)
Long Form:   high mobility group box chromosomal protein 1
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 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2021 High Mobility Group Box Chromosomal Protein-1 Induces Myofibroblast Differentiation and Extracellular Matrix Production via RAGE, p38, JNK and AP-1 Signaling Pathways in Nasal Fibroblasts. alpha-SMA, ECM
2020 HMGB-1/RAGE signaling inhibition by dioscin attenuates hippocampal neuron damage induced by oxygen-glucose deprivation/reperfusion. CAT, CCK-8, GPx, IRI, OGD/R, RAGE, ROS, RT-qPCR, SOD
2020 Omarigliptin Mitigates Lipopolysaccharide-Induced Neuroinflammation and Dysfunction of the Integrity of the Blood-Brain Barrier. BBB, IL-6, IL-8, LPS, MMP-2, MMP-9, TLR4, TNF-alpha
2019 Association of chemokine expression in anterior cruciate ligament deficient knee with patient characteristics: Implications for post-traumatic osteoarthritis. ACL, ACLD, ACLR, PTOA, SF
2019 Impact of perioperative high mobility group box chromosomal protein 1 expression on long-term outcomes in patients with esophageal squamous cell carcinoma. ---
2019 Inhibitions of HMGB1 and TLR4 alleviate DINP-induced asthma in mice. DINP
2019 Linagliptin protects human chondrogenic ATDC5 cells against advanced glycation end products (AGEs)-induced apoptosis via a mitochondria-dependent pathway. AGEs, MMPs, ROS
2019 Resolvin D1 attenuates ventilator-induced lung injury by reducing HMGB1 release in a HO-1-dependent pathway. HO-1, MV, RvD1, VILI
2018 Glycyrrhizin Treatment Facilitates Extinction of Conditioned Fear Responses After a Single Prolonged Stress Exposure in Rats. BLA, PTSD, SPS, TLR4
10  2018 High Efficiency Removal of Cytokines and HMGB-1 by Continuous Hemofiltration With a Dual Layered Polyethersulfone Membrane: An Ex Vivo Study. SCs, TNF-a
11  2017 Association of High Mobility Group Box Chromosomal Protein 1 and Receptor for Advanced Glycation End Products Serum Concentrations With Extraglandular Involvement and Disease Activity in Sjogren's Syndrome. ELISA, ESSDAI, sRAGE, SS
12  2017 Uric Acid Induces Endothelial Dysfunction by Activating the HMGB1/RAGE Signaling Pathway. eNOS, HUVECs, NF-kappaB, NO, RAGE, UA
13  2016 Effects of bone marrow MSCs transfected with sRAGE on the intervention of HMGB1 induced immuno-inflammatory reaction. ALF, sRAGE
14  2016 PKR and HMGB1 expression and function in rheumatoid arthritis. PKR, RA
15  2016 TLR2 Plays a Critical Role in HMGB1-Induced Glomeruli Cell Proliferation Through the FoxO1 Signaling Pathway in Lupus Nephritis. FOXO1, LPS, MMC, mRNA, PCNA, shTLR2, TLR2, WT-FoxO1
16  2016 [EXPRESSION AND FUNCTION OF HIGH MOBILITY GROUP BOX CHROMOSOMAL PROTEIN 1 IN SYNOVIOCYTES OF PATIENTS WITH OSTEOARTHRITIS]. IL-1beta, OA, siRNA, TNF-alpha
17  2015 Autophagy induction contributes to the resistance to methotrexate treatment in rheumatoid arthritis fibroblast-like synovial cells through high mobility group box chromosomal protein 1. mTOR, MTX, OA-FLS, RA-FLS
18  2015 Comments on "Preliminary study of high mobility group box chromosomal protein 1(HMGB1) in ankylosing spondylitis patients ". ---
19  2015 Expression and purification of functional HMGB1 A box by fusion with SUMO. ---
20  2015 IL-1beta mediating high mobility group box protein-1 expression in condylar chondrocyte during temporomandibular joint inflammation. CFA, OA, TMJ
21  2015 Preliminary study of high mobility group box chromosomal protein 1(HMGB1) in ankylosing spondylitis patients. ASDAS, BASDAI, BASFI, CRP, ESR
22  2014 Extracellular high mobility group box chromosomal protein 1 promotes drug resistance by increasing the expression of P‑glycoprotein expression in gastric adenocarcinoma cells. MDR, P-gp
23  2014 Hemoadsorption of high-mobility group box chromosomal protein 1 using a column for large animals. ---
24  2014 High mobility group box 1 release from cholangiocytes in patients with acute-on-chronic liver failure. ACLF, HBV, LPS, TNF
25  2014 Increased of serum high-mobility group box chromosomal protein 1 correlated with intestinal mucosal barrier injury in patients with severe acute pancreatitis. SAP
26  2014 Induction of cytokine production in cholesteatoma keratinocytes by extracellular high-mobility group box chromosomal protein 1 combined with DNA released by apoptotic cholesteatoma keratinocytes. ---
27  2014 Inhibition of HMGB1-induced angiogenesis by cilostazol via SIRT1 activation in synovial fibroblasts from rheumatoid arthritis. CIA, HMVECs, RA
28  2014 Preoperative chemoradiation therapy for esophageal cancer is a risk factor for the elevation of high mobility group box-1, leading to an increase in postoperative severe pulmonary complications. NACRT
29  2014 Recombinant HMGB1 A box protein inhibits Th17 responses in mice with neutrophilic asthma by suppressing dendritic cell-mediated Th17 polarization. APC, DCs, IL-17
30  2014 Serum high mobility group box protein 1 as a clinical marker for ovarian cancer. ---
31  2014 The PTEN/PI3K/Akt signaling pathway mediates HMGB1-induced cell proliferation by regulating the NF-kappaB/cyclin D1 pathway in mouse mesangial cells. LN, MMC, NF-kappaB, PDTC, PI3K, PTEN
32  2013 (Pro)renin receptor blocker improves survival of rats with sepsis. CLP, RAS
33  2013 Bone fracture exacerbates murine ischemic cerebral injury. ---
34  2013 HMGB1 acts in synergy with lipopolysaccharide in activating rheumatoid synovial fibroblasts via p38 MAPK and NF-kappaB signaling pathways. HMGB1-LPS, LPS, RA, RAGE, SF
35  2013 HMGB1 gene polymorphisms in patients with chronic hepatitis B virus infection. HBV
36  2013 HMGB1 levels are increased in patients with juvenile idiopathic arthritis, correlate with early onset of disease, and are independent of disease duration. JIA, RA, SF
37  2013 IL-1beta/HMGB1 complexes promote The PGE2 biosynthesis pathway in synovial fibroblasts. mPGES-1, SFs
38  2013 The role of high mobility group box chromosomal protein 1 in rheumatoid arthritis. ---
39  2012 Chondrogenic progenitor cells respond to cartilage injury. RAGE
40  2012 High mobility group box chromosomal protein 1 in acute-on-chronic liver failure patients and mice with ConA-induced acute liver injury. ACLF, Con A, PBMCs
41  2012 Interleukin-33 in allergy. IL-1RAcP, IL-33, IL1RL1
42  2012 Role of high mobility group box chromosomal protein 1 in ischemia-reperfusion injury in the rat small intestine. control group
43  2011 Enhanced HMGB1 expression may contribute to Th17 cells activation in rheumatoid arthritis. PBMCs, RA
44  2011 Expression of HMGB1 and HMGN2 in gingival tissues, GCF and PICF of periodontitis patients and peri-implantitis. CP, GAgP, GCF, HMG, PICF
45  2011 Expression of HMGB1 and HMGN2 in gingival tissues, GCF and PICF of periodontitis patients and peri-implantitis. CP, GAgP, GCF, HMG, PICF
46  2011 Gene expression and localization of high-mobility group box chromosomal protein-1 (HMGB-1)in human osteoarthritic cartilage. OA, OARSI, RAGE
47  2011 High-dose immunoglobulin preparations improve survival in a CLP-induced rat model of sepsis. CLP, POH
48  2011 HMGB-1 induces IL-6 production in human synovial fibroblasts through c-Src, Akt and NF-kappaB pathways. Ab, RAGE
49  2011 Lipopolysaccharide-induced Notch signaling activation through JNK-dependent pathway regulates inflammatory response. VEGF
50  2011 Monoclonal anti-HMGB1 (high mobility group box chromosomal protein 1) antibody protection in two experimental arthritis models. CIA, mAb
51  2011 Polydeoxyribonucleotide reduces cytokine production and the severity of collagen-induced arthritis by stimulation of adenosine A(₂A) receptor. CIA, DMPX, IL-6, PDRN, TNF-alpha
52  2011 [Expression of high mobility group box chromosomal protein 1 in mice with lupus nephritis]. ELISA, MCP-1
53  2010 Chondrocyte innate immune myeloid differentiation factor 88-dependent signaling drives procatabolic effects of the endogenous Toll-like receptor 2/Toll-like receptor 4 ligands low molecular weight hyaluronan and high mobility group box chromosomal protein 1 in mice. LMW-HA, MMP-3, MyD88, NO, OA, TLR2
54  2010 Expression and purification of the fusion protein HMGB1Abox-TMD1, a novel HMGB1 antagonist. ---
55  2010 Expression of high mobility group box chromosomal protein 1 and its modulating effects on downstream cytokines in systemic lupus erythematosus. IL-6, mRNA, PBMC, SLE, TNF-alpha
56  2010 High mobility group box 1 induces synoviocyte proliferation in rheumatoid arthritis by activating the signal transducer and activator transcription signal pathway. CIA, IL-6, STAT
57  2010 High-mobility-group box chromosomal protein 1 as a new target for modulating stress response. SIRS
58  2010 HMGB1 activates nuclear factor-kappaB signaling by RAGE and increases the production of TNF-alpha in human umbilical vein endothelial cells. EP, HUVECs, NF-kappaB, RAGE, TNF-alpha
59  2010 Preconditioning with high mobility group box 1 (HMGB1) induces lipoteichoic acid (LTA) tolerance. LTA, RAGE, TLR
60  2010 Protective targeting of high mobility group box chromosomal protein 1 in a spontaneous arthritis model. ELISA
61  2010 Spherical sulfated cellulose adsorbs high-mobility-group box chromosomal protein 1 in vitro and in vivo. IL, SC, SC
62  2010 [Effect of qinghuobaiduyin on the expression of high mobility group box chromosomal protein 1 in macrophage]. QHBDY
63  2009 Circulating levels of a soluble form of receptor for advanced glycation end products and high-mobility group box chromosomal protein 1 in patients with acute pancreatitis. AP, IQR, sRAGE
64  2009 Clinical value of serum HMGB1 levels in early detection of recurrent squamous cell carcinoma of uterine cervix: comparison with serum SCCA, CYFRA21-1, and CEA levels. AUC, CEA, CSCC, CYFRA, ROC, SCCA
65  2009 High mobility group box chromosomal protein 1 acts as a proliferation signal for activated T lymphocytes. ---
66  2009 High-mobility group box chromosomal protein 1 as a potential inflammatory biomarker of joint injury in Thoroughbreds. MCP, MTP, SF
67  2009 Neutrophil elastase inhibitor improves survival of rats with clinically relevant sepsis. CLP
68  2009 Recipient Toll-like receptors contribute to chronic graft dysfunction by both MyD88- and TRIF-dependent signaling. alpha-SMA, BGN, CAD, DCs, GRP, HSP, IL, MCP-1, TLRs
69  2009 The vagus nerve and nicotinic receptors involve inhibition of HMGB1 release and early pro-inflammatory cytokines function in collagen-induced arthritis. CIA, IL, NIC, RA, TNF
70  2008 A high incidence of disease flares in an open pilot study of infliximab in patients with refractory inflammatory myopathies. DM, IBM, IFN-gamma, IL, IMACS, MAC, MHC, MxA, PM, TNF
71  2008 Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis. CIA, SF
72  2008 High mobility group box (HMGB) proteins of Plasmodium falciparum: DNA binding proteins with pro-inflammatory activity. EMSA, HMGB, PfHMGB1
73  2008 High mobility group box chromosomal protein 1 in patients with renal diseases. ANCA-GN, IgAN
74  2008 Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling. ---
75  2008 Oxaliplatin retains HMGB1 intranuclearly and ameliorates collagen type II-induced arthritis. ---
76  2008 Pivotal advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis. EAE, MS
77  2008 Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients--a prospective clinical study. DAS28, RA, RT-PCR
78  2008 [The plasmic translocation and release of high mobility group box chromosomal protein 1 in peripheral blood monocytes of patients with rheumatoid arthritis and the effect of thalidomide]. RA, TNF-alpha
79  2007 Elevated levels of high mobility group box chromosomal protein-1 (HMGB-1) in sera from patients with severe bacterial pneumonia coinfected with influenza virus. IL-6, RANTES, sICAM-1
80  2007 Expression of high mobility group box chromosomal protein-1 (HMGB-1) in gastric cancer. ---
81  2007 Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis. IL-1beta, TNF
82  2007 Neutrophil elastase inhibitor improves postoperative clinical courses after thoracic esophagectomy. ICU, NE, SIRS
83  2007 Pivotal advance: inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate. GST, RA
84  2007 [Expression of high mobility group box chromosomal protein 1 in peripheral blood of patients with rheumatoid arthritis]. CRP, ESR, PBMCs, RA, RT-PCR
85  2007 [Role of HMGB1 in rheumatic diseases]. ---
86  2006 Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis. CLP
87  2006 Increased extracellular levels of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in minor salivary glands of patients with Sjogren's syndrome. IL-1beta, SS, TNF
88  2006 Significant increase of serum high-mobility group box chromosomal protein 1 levels in patients with severe acute pancreatitis. SAP
89  2006 Soluble receptor for advanced glycation end products triggers a proinflammatory cytokine cascade via beta2 integrin Mac-1. RAGE, sRAGE
90  2006 The high mobility group box chromosomal protein 1 is expressed in the human and rat testis where it may function as an antibacterial factor. HPLC
91  2005 Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis. IL-1, MMP-13, OA, RAGE, RT-PCR
92  2005 Increased expression of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in skin lesions of patients with lupus erythematosus. CLE, IL-1beta, TNF-alpha
93  2005 Intraarticular glucocorticoid treatment reduces inflammation in synovial cell infiltrations more efficiently than in synovial blood vessels. GC, IA, ICAM-1, IL-1alpha, TNF, VEGF
94  2005 Plasma concentrations and importance of High Mobility Group Box protein in the prognosis of organ failure in patients with disseminated intravascular coagulation. DIC, SOFA
95  2005 RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. DA, IL, MAPK, MHC, NF-kappaB, TNF
96  2005 Serum concentrations of high-mobility group box chromosomal protein 1 before and after exposure to the surgical stress of thoracic esophagectomy: a predictor of clinical course after surgery? ---
97  2004 A citrus flavonoid hesperidin suppresses infection-induced endotoxin shock in mice. HES, i.p, TNF
98  2004 Activation of human umbilical vein endothelial cells leads to relocation and release of high-mobility group box chromosomal protein 1. HUVEC, IL, LPS, TNF
99  2004 Down-regulation of the aberrant expression of the inflammation mediator high mobility group box chromosomal protein 1 in muscle tissue of patients with polymyositis and dermatomyositis treated with corticosteroids. DM, PM
100  2004 HMGB1 is a potent trigger of arthritis. IL-1, RA, TNF