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■ Abbreviation / Long Form : HMGB / high mobility group box

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Total Number of Papers: 183
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Abbreviation:   HMGB  (>> Co-occurring Abbreviation)
Long Form:   high mobility group box
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2021 A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle. ---
2021 Activation of Peripheral Blood Mononuclear Cells and Leptin Secretion: New Potential Role of Interleukin-2 and High Mobility Group Box (HMGB)1. HMGB1, IL-2, NK, PBMCs, T2DM, TLR2, TLRs
2021 Changes in Stress-Mediated Markers in a Human Cardiomyocyte Cell Line under Hyperglycemia. CXCR, HDAC, HSP, RAGE, SIRT1, TLR
2021 Designed architectural proteins that tune DNA looping in bacteria. TALE
2021 HMGB-1 and TGFbeta-1 highlight immuno-inflammatory and fibrotic processes before proteinuria onset in pediatric patients with Alport syndrome. ALP, beta, eGFR, HS, TGF
2021 HMGB1 Mediated Inflammation and Autophagy Contribute to Endometriosis. ATG, HESCs, IL, LC, TNF
2021 Interactions of HMGB Proteins with the Genome and the Impact on Disease. ---
2021 LPS Primes Brain Responsiveness to High Mobility Group Box-1 Protein. AP, NF
2021 microRNA-130a-5p suppresses myocardial ischemia reperfusion injury by downregulating the HMGB2/NF-kappaB axis. HE, MIRI, miRs, NF-kappaB, RT-qPCR
10  2021 miR-665 is downregulated in glioma and inhibits tumor cell proliferation, migration and invasion by targeting high mobility group box 1. ---
11  2021 Phosphodiesterase (1, 3 & 5) inhibitors attenuate diclofenac-induced acute kidney toxicity in rats. NF, TLR, TNF
12  2021 Potential neurotoxic activity of diverse molecules released by microglia. Cat, CXCL, LT, MMP, PAF, PEP
13  2021 Roles of HMGBs in Prognosis and Immunotherapy: A Pan-Cancer Analysis. GSEA, ICP, MSI, TIICs, TIME, TMB
14  2021 Sitagliptin ameliorates hypoxia-induced damages in endometrial stromal cells: an implication in endometriosis. COX-2, DPP-4, ESCs, IL, MAPK, MCP-1, NF-kappaB, PGE2, ROS, TNF
15  2021 The HMGB Protein KlIxr1, a DNA Binding Regulator of Kluyveromyces lactis Gene Expression Involved in Oxidative Metabolism, Growth, and dNTP Synthesis. ---
16  2021 Verbascoside inhibits the epithelial-mesenchymal transition of prostate cancer cells through high-mobility group box 1/receptor for advanced glycation end-products/TGF-beta pathway. EMT, RAGE
17  2021 Xuebijing injection in septic rats mitigates kidney injury, reduces cortical microcirculatory disorders, and suppresses activation of local inflammation. CLP, Cxbj, IL, NGAL, SCr, sham, Sxbj, TCM, TNF
18  2020 Abdominal paracentesis drainage ameliorates myocardial injury in severe experimental pancreatitis rats through suppressing oxidative stress. APD, SAP
19  2020 Biological functions and theranostic potential of HMGB family members in human cancers. ---
20  2020 Endothelial cell-derived extracellular vesicles alter vascular smooth muscle cell phenotype through high-mobility group box proteins. ECs, EVs, VCAM-1, VSMC
21  2020 Identification of the hallmarks of necroptosis and ferroptosis by transmission electron microscopy. DAMPs
22  2020 Improved viability and fertility of frozen-thawed dog sperm using adipose-derived mesenchymal stem cells. ADMSCs, ANX1
23  2020 In vitro studies on non-canonical DNA binding specificities of KAP6 and HMO1 and mechanistic insights into DNA bound and unbinding dynamics of KAP6. HJ, HMO1
24  2020 Kaempferol Improves Lung Ischemia-Reperfusion Injury via Antiinflammation and Antioxidative Stress Regulated by SIRT1/HMGB1/NF-kappaB Axis. IL, LIRI, SIRT, TNF
25  2020 Targeting Chromosomal Architectural HMGB Proteins Could Be the Next Frontier in Cancer Therapy. ---
26  2020 The HMGB1-2 Ovarian Cancer Interactome. The Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response. EOC, TCC
27  2019 Autophagy Activation Improves Lung Injury and Inflammation in Sepsis. ALI/ARDS, Baf, BALF, CLP, CQ, IL, LAMP2, LC3II, MCP, MPO, PMN, TNF
28  2019 Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer. CI, GC, HR
29  2019 Characterization of HMGB1/2 Interactome in Prostate Cancer by Yeast Two Hybrid Approach: Potential Pathobiological Implications. CNA, PCa, Y2H
30  2019 Evaluation of Parameters for Cancer-Induced Sarcopenia in Patients Autopsied after Death from Colorectal Cancer. CRC, IL, SDS-MYL1, SMI, TNF
31  2019 HMGB proteins are required for sexual development in Aspergillus nidulans. ---
32  2019 HMGB2 is a negative regulator of telomerase activity in human embryonic stem and progenitor cells. hESCs, KD, TERRA
33  2019 Multiple Sclerosis: Melatonin, Orexin, and Ceramide Interact with Platelet Activation Coagulation Factors and Gut-Microbiome-Derived Butyrate in the Circadian Dysregulation of Mitochondria in Glia and Immune Cells. AhR, CoA, LPS, MS, NAS, TLR
34  2019 Nrf2/HO-1 signaling pathway participated in the protection of hydrogen sulfide on neuropathic pain in rats. CCI, ELISA, HO-1, IL, NF-E2, NF-kappaB, RT-PCR, SnPP, TNF, WB
35  2018 Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer. MS
36  2018 Effect of in vivo post-translational modifications of the HMGB1 protein upon binding to platinated DNA: a molecular simulation study. PtDNA, PTMs
37  2018 Exercise alarms the immune system: A HMGB1 perspective. ---
38  2018 Functional roles of the DNA-binding HMGB domain in the histone chaperone FACT in nucleosome reorganization. FACT
39  2018 HMGB proteins involved in TOR signaling as general regulators of cell growth by controlling ribosome biogenesis. TOR
40  2018 Increased Plasma Levels of Danger-Associated Molecular Patterns Are Associated With Immune Suppression and Postoperative Infections in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy. CRS, DAMPs, HIPEC, HSP, LDH, MIP, mt, TNF
41  2018 Molecular and functional characterization of single-box high-mobility group B (HMGB) chromosomal protein from Aedes aegypti. ---
42  2018 Overexpression of miR-758 inhibited proliferation, migration, invasion, and promoted apoptosis of non-small cell lung cancer cells by negatively regulating HMGB. miRs, NSCLC, RT-qPCR
43  2018 Reduction in replication-independent endogenous DNA double-strand breaks promotes genomic instability during chronological aging in yeast. HO, OR, RIND-EDSBs
44  2018 Selective ablation of ligament of Marshall inhibits ventricular arrhythmias during acute myocardial infarction: Possible mechanisms. AMI, AMI, IL-6, LSG, MDA, SO, SOD, TNF, VAs
45  2018 Single and double box HMGB proteins differentially destabilize nucleosomes. AFM, OT
46  2018 Small molecule disruption of G protein betagamma subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats. EAM, GRK, HF, Th1
47  2017 alpha7-nAChR Activation Has an Opposite Effect on Healing of Covered and Uncovered Wounds. alpha7nAChR, EGF, IL-6, VEGF
48  2017 Association of Serum HMGB2 Levels With In-Stent Restenosis: HMGB2 Promotes Neointimal Hyperplasia in Mice With Femoral Artery Injury and Proliferation and Migration of VSMCs. ISR
49  2017 Characterization of NLRP3-like gene from Apostichopus japonicus provides new evidence on inflammation response in invertebrates. aa, CTSB, NLRP
50  2017 Fingolimod anti-inflammatory and neuroprotective effects modulation of RAGE axis in multiple sclerosis patients. MS, RAGE
51  2017 High Expression of High-Mobility Group Box 1 in Menstrual Blood: Implications for Endometriosis. ESCs, LPS, RAGE, VEGF
52  2017 High mobility group box 1 in diabetic nephropathy. DN, T2D
53  2017 HMGB proteins and arthritis. LEF1, OA, SZ
54  2017 HMGB3 promotes growth and migration in colorectal cancer by regulating WNT/beta-catenin pathway. CRC, HMGB3, TNM
55  2017 Isoglycyrrhizinate Magnesium Enhances Hepatoprotective Effect of FK506 on Ischemia-Reperfusion Injury Through HMGB1 Inhibition in a Rat Model of Liver Transplantation. Iso, LT
56  2017 Minocycline Attenuates High Mobility Group Box 1 Translocation, Microglial Activation, and Thalamic Neurodegeneration after Traumatic Brain Injury in Post-Natal Day 17 Rats. CCI, FJB, TBI
57  2017 Single-molecule studies of high-mobility group B architectural DNA bending proteins. ---
58  2017 The potential curative effect of rebamipide in hepatic ischemia/reperfusion injury. I/R, NF, Reba, SIRT-1
59  2017 The role of HMGB1 in heart transplantation. ---
60  2017 Trypanosoma cruzi High Mobility Group B (TcHMGB) can act as an inflammatory mediator on mammalian cells. DAMPs, PAMP, TcHMGB
61  2016 A high-mobility group box 1 that binds to DNA, enhances pro-inflammatory activity, and acts as an anti-infection molecule in black rockfish, Sebastes schlegelii. HK, UTR
62  2016 Association of serum HMGB2 level with MACE at 1 mo of myocardial infarction: Aggravation of myocardial ischemic injury in rats by HMGB2 via ROS. MACE, MI, RAGE, ROS
63  2016 Effect of alpha-lipoic acid on relieving ammonia stress and hepatic proteomic analyses of broilers. AM, CTRL, GST, LA
64  2016 Genome-Wide Overexpression Screen Identifies Genes Able to Bypass p16-Mediated Senescence in Melanoma. HPV18E7, ORFs
65  2016 Histone H3 and TORC1 prevent organelle dysfunction and cell death by promoting nuclear retention of HMGB proteins. TORC1
66  2016 Improved prescription of taohechengqi-tang alleviates D-galactosamine acute liver failure in rats. ALF, IPTT, NF-kappaB, PCNA, SNMC, TLR
67  2016 Inhibition of the translocation and extracellular release of high-mobility group box 1 alleviates liver damage in fibrotic mice in response to D-galactosamine/lipopolysaccharide challenge. D-GalN, IL, LPS
68  2016 Key Role of DAMP in Inflammation, Cancer, and Tissue Repair. DAMP, RAGE
69  2016 MicroRNA-205‑5b inhibits HMGB1 expression in LPS-induced sepsis. CAP
70  2016 Protective Role of Grape Seed Proanthocyanidins Against Ccl4 Induced Acute Liver Injury in Mice. AST, GSH-Px, GSPs, IL-6, MDA, SOD, TNF
71  2016 Recombinant human soluble thrombomodulin ameliorates cerebral ischemic injury through a high-mobility group box 1 inhibitory mechanism without hemorrhagic complications in mice. MCAO, rhsTM
72  2016 The distinct C-terminal acidic domains of HMGB proteins are functionally relevant in Schistosoma mansoni. ---
73  2016 The high mobility group protein HMO1 functions as a linker histone in yeast. ---
74  2016 Yeast HMO1: Linker Histone Reinvented. rDNA
75  2015 Disruption of Parasite hmgb2 Gene Attenuates Plasmodium berghei ANKA Pathogenicity. ECM
76  2015 Further characterization of the role of the mitochondrial high-mobility group box protein in the intracellular redox environment of Aspergillus nidulans. ROS
77  2015 H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. CCI, CORM, DRG, ELISA, HO, mRNA, NP
78  2015 High Mobility Group B Proteins, Their Partners, and Other Redox Sensors in Ovarian and Prostate Cancer. ---
79  2015 High-mobility group box 1 in multiple sclerosis. DMDs, HCs, MS
80  2015 IFN-gamma-producing Th17 cells bias by HMGB1-T-bet/RUNX3 axis might contribute to progression of coronary artery atherosclerosis. AP, CA, PR, TH
81  2015 Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: A ticking time bomb in ageing. DAMPs, MSU, ROS
82  2015 Modulation of HMGB1 translocation and RAGE/NFkappaB cascade by quercetin treatment mitigates atopic dermatitis in NC/Nga transgenic mice. AD, COX, ERK, IFN, IL, Keap, NF, Nrf, RAGE, Th, TLR, TNF
83  2015 Overexpression of HMGB1 A-box reduced lipopolysaccharide-induced intestinal inflammation via HMGB1/TLR4 signaling in vitro. EP, IL, LPS, MyD88, pNF-kappaB, TLR, TNF
84  2015 Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects. ATX, CNS, i.p, LPS, MMP, PND, TLR
85  2015 Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension. IL, iNOS, MAP, NE, NF, PVN, SHR, TLR, TNF, VIPER, WKY
86  2015 Yeast high mobility group protein HMO1 stabilizes chromatin and is evicted during repair of DNA double strand breaks. DSBs
87  2014 A small molecule binding HMGB1 and HMGB2 inhibits microglia-mediated neuroinflammation. ICM
88  2014 A systematic nomenclature for the redox states of high mobility group box (HMGB) proteins. HMGB1
89  2014 Antibacterial and antiviral properties of tongue sole (Cynoglossus semilaevis) high mobility group B2 protein are largely independent on the acidic C-terminal domain. qRT-PCR, rCsHMGB2
90  2014 Decreased level of sRAGE in the cerebrospinal fluid of multiple sclerosis patients at clinical onset. CSF, IL, MS, PBL, PBMCs, RAGE, S100A12, sRAGE, TNF
91  2014 DNA bridging and looping by HMO1 provides a mechanism for stabilizing nucleosome-free chromatin. AFM
92  2014 Dynamic localization and the associated translocation mechanism of HMGBs in response to GCRV challenge in CIK cells. CIK, GCRV, LPS
93  2014 High-mobility group box 1 up-regulates aquaporin 4 expression via microglia-astrocyte interaction. AQP, i.c.v, IL, NF
94  2014 HMGB1 as a drug target in staphylococcal pneumonia. ---
95  2014 JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation. IFN, NLS
96  2014 Log-odds sequence logos. ---
97  2014 Nucleosome remodeling by the SWI/SNF complex is enhanced by yeast high mobility group box (HMGB) proteins. HMG
98  2014 Resveratrol attenuates HMGB1 signaling and inflammation in house dust mite-induced atopic dermatitis in mice. AD, COX, ERK, IFN, IL, NF, PI3K, RAGE, Th, TLR, TNF
99  2014 The combination of a nuclear HMGB1-positive and HMGB2-negative expression is potentially associated with a shortened survival in patients with pancreatic ductal adenocarcinoma. PDAC
100  2014 Therapeutic potential of transgenic mesenchymal stem cells engineered to mediate anti-high mobility group box 1 activity: targeting of colon cancer. MSCs