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■ Abbreviation / Long Form : IGF-1R / insulin-like growth factor-1 receptor

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Abbreviation:   IGF-1R  (>> Co-occurring Abbreviation)
Long Form:   insulin-like growth factor-1 receptor
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2022 Analysis on the Efficacy of Bronchial Artery Chemoembolization Combined with 125I Seed Implantation in the Therapy of Advanced Non-Small-Cell Lung Cancer Based on the Medical Database. BACE, CA125, CEA, CYFRA21-1, NSCLC, S100A2
2022 Co-delivery of siRNA and lycopene encapsulated hybrid lipid nanoparticles for dual silencing of insulin-like growth factor 1 receptor in MCF-7 breast cancer cell line. DDAB, NPs
2022 Cognitive disorder and dementia in type 2 diabetes mellitus. AD, DM
2022 Correlation of Serum IGF-1R, VEGF, and ET Levels with Bone Mineral Density in Type 2 Diabetic Mellitus Patients Treated with Metformin Plus α-Glucosidase Inhibitors. BMD, ET, T2DM, VEGF
2022 Dual Inhibition of EGFR and IGF-1R Signaling Leads to Enhanced Antitumor Efficacy against Esophageal Squamous Cancer. EGFR, ESCC
2022 Effect of Pinoresinol and Vanillic Acid Isolated from Catalpa bignonioides on Mouse Myoblast Proliferation via the Akt/mTOR Signaling Pathway. mTOR
2022 Effects of Fuyou Formula on GnRH Secretion and Related Gene Expression in Treating Precocious Puberty. ERalpha, Fy, GnRH, GnRHR, GPR54, IGF-1, Kiss1, PP, TCM
2022 Effects of targeted-edited oncogenic insulin-like growth factor-1 receptor with specific-sgRNA on biological behaviors of HepG2 cells. HCC, non-Ca, P-gp
2022 Glycan Modulation of Insulin-like Growth Factor-1 Receptor. HS, RTK
10  2022 Heidihuangwan alleviates renal fibrosis in rats with 5/6 nephrectomy by inhibiting autophagy. alpha-SMA, AS-IV, CKD, HDHW, HE, IGF-1, PAS, PI3K, TGF-beta
11  2022 Hyperinsulinemia induces early and dyssynchronous puberty in lean female mice. LH, VO
12  2022 Hypoxia-induced CXC chemokine ligand 14 expression drives protumorigenic effects through activation of insulin-like growth factor-1 receptor signaling in glioblastoma. CXCL14, HIF, HTM, NPs
13  2022 IGF-1 receptor regulates upward firing rate homeostasis via the mitochondrial calcium uniporter. MCUC
14  2022 IGF-1R/YAP signaling pathway is involved in collagen V-induced insulin biosynthesis and secretion in rat islet INS-1 cells. ECM, LATS, YAP
15  2022 Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer. CRC, ERI, MTAs
16  2022 Insulin facilitates corneal wound healing in the diabetic environment through the RTK-PI3K/Akt/mTOR axis in vitro. IR
17  2022 Insulin Receptor Genetic Variants Causal Association with Type 2 Diabetes: A Mendelian Randomization Study. DIAMANTE, GWASs, INS, INSR, MR, SNPs, T2D, WM
18  2022 Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection. ---
19  2022 Knockdown of circular RNA tousled-like kinase 1 relieves ischemic stroke in middle cerebral artery occlusion mice and oxygen-glucose deprivation and reoxygenation-induced N2a cell damage. circTLK1, GLUT1, IS, MCAO, OGD/R, PTEN
20  2022 MiR-143 Targets IGF-1R to Suppress Autoimmunity in Thyroid-Associated Ophthalmopathy. OFs, TAO, TSHR
21  2022 MiR-448 suppresses cell proliferation and glycolysis of hepatocellular carcinoma through inhibiting IGF-1R expression. 3'UTRs, ATP, HCC, miRNAs, qRT-PCR
22  2022 Molecular Mechanisms, Biomarkers and Emerging Therapies for Chemotherapy Resistant TNBC. ABC, ADAM10, AR, CSCs, CT, EGFR, mTNBC, mTOR, NACT, NTRK, OS, PI3K, TNBC, Trop2
23  2022 New insights into the prognosis of intraocular malignancy: Interventions for association mechanisms between cancer and diabetes. Rb, UM
24  2022 Picropodophyllin Inhibits the Proliferation of Human Prostate Cancer DU145 and LNCaP Cells via ROS Production and PI3K/AKT Pathway Inhibition. PI3K, PPP, ROS
25  2022 PINCH-1 promotes IGF-1 receptor expression and skin cancer progression through inhibition of the GRB10-NEDD4 complex. DMBA, TPA
26  2022 Preclinical Evaluation of a New Format of 68Ga- and 111In-Labeled Affibody Molecule ZIGF-1R:4551 for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT. ---
27  2022 Progerin modulates the IGF-1R/Akt signaling involved in aging. HGPS
28  2022 Prognostic value of receptor tyrosine kinases in malignant melanoma patients: A systematic review and meta-analysis of immunohistochemistry. DFS, EGFR, IHC, MET, OS, PFS, RTKs, VEGFR1, VEGFR2
29  2022 Relevance of miR-223 as Potential Diagnostic and Prognostic Markers in Cancer. C. elegans, Caprin-1
30  2022 Role of IGF-1R in epithelial-mesenchymal transdifferentiation of human peritoneal mesothelial cells. EMT, HG, HPMCs, PDF, PF
31  2022 The clinicopathological and prognostic significances of IGF-1R and Livin expression in patients with colorectal cancer. CRC, IHC
32  2022 The regulation of proliferation and apoptosis in hepatocellular carcinoma via insulin-like growth factor 1 receptor. BMP, HCC, PI3K
33  2022 Thyroid eye disease: From pathogenesis to targeted therapies. OFs, TED
34  2022 Treating Thyroid Associated Ophthalmopathy in Pediatric Patients. TAO
35  2022 Tyrphostin AG1024 Suppresses Coronaviral Replication by Downregulating JAK1 via an IR/IGF-1R Independent Proteolysis Mediated by Ndfip1/2_NEDD4-like E3 Ligase Itch. IR, TGEV
36  2021 3D Tissue-Engineered Tumor Model for Ewing's Sarcoma That Incorporates Bone-like ECM and Mineralization. ECM, ES, mTOR, PCL
37  2021 A case of ulcerative colitis associated with teprotumumab treatment for thyroid eye disease. IBD, UC
38  2021 A phase-1 trial of linsitinib (OSI-906) in combination with bortezomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma. PI
39  2021 A review on the molecular basis underlying the protective effects of Andrographis paniculata and andrographolide against myocardial injury. MAPK, NF-kappaB, Nrf2, PI3K, PPAR-alpha, STAT3
40  2021 A viral insulin-like peptide is a natural competitive antagonist of the human IGF-1 receptor. LCDV1, VILPs
41  2021 A Yes-Associated Protein (YAP) and Insulin-Like Growth Factor 1 Receptor (IGF-1R) Signaling Loop Is Involved in Sorafenib Resistance in Hepatocellular Carcinoma. CI, VP, YAP
42  2021 Activity-dependent conformational transitions of the insulin receptor-related receptor. IR, IRR
43  2021 An affibody-conjugated nanoprobe for IGF-1R targeted cancer fluorescent and photoacoustic dual-modality imaging. ---
44  2021 Analysis of Increased EGFR and IGF-1R Signaling and Its Correlation with Socio-Epidemiological Features and Biological Profile in Breast Cancer Patients: A Study in Northern Brazil. AUC, BC, EGFR
45  2021 Cannabinoid receptors promote chronic intermittent hypoxia-induced breast cancer metastasis via IGF-1R/AKT/GSK-3beta. CBs, CH, CIH, GSK-3beta, OSAHS
46  2021 Cezanne contributes to cancer progression by playing a key role in the deubiquitination of IGF-1R. ---
47  2021 Clinical significance of microRNA-320a and insulin-like growth factor-1 receptor in early-onset preeclampsia patients. ALB, EOPE, MAP, miRs, SCr, UA
48  2021 Collagen type I enhances cell growth and insulin biosynthesis in rat pancreatic cells. ECM
49  2021 Comparisons of +3179G/A insulin-like growth factor 1 receptor gene distribution between two inflammatory arthritides and healthy adults. AS, OR, RA, SNPs
50  2021 Cytokines as Targets of Novel Therapies for Graves' Ophthalmopathy. GD, GO, TSHR
51  2021 Dietary isoleucine improved flesh quality, muscle antioxidant capacity, and muscle growth associated with AKT/TOR/S6K1 and AKT/FOXO3a signaling in hybrid bagrid catfish (Pelteobagrus vachelli♀ Leiocassis longirostris♂). Ile, MDA, PC, PCNA, ROS
52  2021 Dihydroartemisinin Inhibits mTORC1 Signaling by Activating the AMPK Pathway in Rhabdomyosarcoma Tumor Cells. AMPK, DHA, FKBP12, mTOR, PI3K, PTEN, RMS
53  2021 Diversity of insulin and IGF signaling in breast cancer: Implications for therapy. IR
54  2021 Dysregulation of miRNAs Targeting the IGF-1R Pathway in Pancreatic Ductal Adenocarcinoma. miRNAs, PDAC
55  2021 Endothelium-gut communication: IGF-1Rs crosstalk with microbiota. ---
56  2021 GPER and IGF-1R mediate the anti-inflammatory effect of genistein against lipopolysaccharide (LPS)-induced nigrostriatal injury in rats. COX-2, DA, GPER, IL-1beta, iNOS, LPS, PD, SN, TH-ir, TNF-alpha
57  2021 Growth Factors, PI3K/AKT/mTOR and MAPK Signaling Pathways in Colorectal Cancer Pathogenesis: Where Are We Now? CRC, EGFR, GFs, MAPK, mTOR, PI3K, TME, VEGFA
58  2021 HOXB13 promotes gastric cancer cell migration and invasion via IGF-1R upregulation and subsequent activation of PI3K/AKT/mTOR signaling pathway. FTO, GC, GEPIA, MeRIP-seq
59  2021 IGF-1 protects against angiotensin II-induced cardiac fibrosis by targeting alphaSMA. alpha-SMA, ROCK
60  2021 IGF-1 Receptor Signaling Regulates Type II Pneumocyte Senescence and Resulting Macrophage Polarization in Lung Fibrosis. AECII
61  2021 IGF-1R anti-idiotypic antibody antagonist exhibited anti-ovarian cancer bioactivity and reduced cisplatin resistance. ---
62  2021 IGF-1R depletion sensitizes colon cancer cell lines to radiotherapy. CRC, DSB, NHEJ, siRNA
63  2021 Insulin-Like Growth Factor 1 Receptor Drives Hepatocellular Carcinoma Growth and Invasion by Activating Stat3-Midkine-Stat3 Loop. HCC, JAK
64  2021 Insulin-Like Growth Factor-1 Receptor Targeted Fluorescent Imaging for Gallbladder Cancer in Orthotopic Mouse Models. ---
65  2021 Insulin-Like Growth Factors-1 Receptor (IGF-1R) Expression and the Phosphorylation of Endogenous Substrates Lead to Maturation of the Pacific oyster, Crassostrea gigas. CI, SDS-PAGE, TWR
66  2021 Investigating differences between tamoxifen resistant and sensitive breast cancer cells with flow cytometry. EGFR
67  2021 Long noncoding RNA LINC01291 promotes the aggressive properties of melanoma by functioning as a competing endogenous RNA for microRNA-625-5p and subsequently increasing IGF-1R expression. miR-625-5p
68  2021 microRNA-203 Targets Insulin-Like Growth Factor Receptor 1 to Inhibit Trophoblast Vascular Remodeling to Augment Preeclampsia. miR, MMP-9
69  2021 miR-210 and miR-152 as Biomarkers by Liquid Biopsy in Invasive Ductal Carcinoma. BBC, BC, HIF-1alpha, ROC, VEGF, VHL
70  2021 miR-301a-3p induced by endoplasmic reticulum stress mediates the occurrence and transmission of trastuzumab resistance in HER2-positive gastric cancer. ER, FGFR1, GC, HER2, LRIG1
71  2021 Modulating TSH Receptor Signaling for Therapeutic Benefit. GD, GO, HLA-DR, TSHR
72  2021 Niche Laminin and IGF-1 Additively Coordinate the Maintenance of Oct-4 Through CD49f/IGF-1R-Hif-2alpha Feedforward Loop in Mouse Germline Stem Cells. ECM, GSCs
73  2021 Pan-Cancer Analysis of IGF-1 and IGF-1R as Potential Prognostic Biomarkers and Immunotherapy Targets. CCLE, DNMT, IGF-1, MMR, MSI, OS, TMB
74  2021 Pathways in Skeletal Muscle: Protein Signaling and Insulin Sensitivity after Exercise Training and Weight Loss Interventions in Middle-Aged and Older Adults. AEX, GSK-beta3, IR, IRS-1, JNK, WL
75  2021 Pharmacological Inhibition of Insulin Growth Factor-1 Receptor (IGF-1R) Alone or in Combination With Ruxolitinib Shows Therapeutic Efficacy in Preclinical Myeloproliferative Neoplasm Models. MPN
76  2021 PKM2 Regulates HSP90-Mediated Stability of the IGF-1R Precursor Protein and Promotes Cancer Cell Survival during Hypoxia. Hsp90
77  2021 Platelet-Rich Plasma Promotes the Proliferation of Human Keratinocytes via a Progression of the Cell Cycle. A Role of Prolidase. EGFR, HaCaT, PRP
78  2021 Prognostic and Therapeutic Utility of Variably Expressed Cell Surface Receptors in Osteosarcoma. EFS, HER2, IR, OS, PDGFR-beta, VEGFR-3
79  2021 Ropivacaine suppresses tumor biological characteristics of human hepatocellular carcinoma via inhibiting IGF-1R/PI3K/AKT/mTOR signaling axis. ---
80  2021 Sensorineural Hearing Loss After Teprotumumab Therapy for Thyroid Eye Disease: A Case Report. SNHL, TED
81  2021 SUMO1 modification of IGF-1R combining with SNAI2 inhibited osteogenic differentiation of PDLSCs stimulated by high glucose. PDLSCs
82  2021 Targeting TSH and IGF-1 Receptors to Treat Thyroid Eye Disease. GD, GH, HA, TED, TSAbs, TSHR
83  2021 Thyroid Eye Disease, Teprotumumab, and Hearing Loss: An Evolving Role for Otolaryngologists. IGF-1
84  2021 Thyroid hormone mediates cardioprotection against postinfarction remodeling and dysfunction through the IGF-1/PI3K/AKT signaling pathway. LAD, MI, p-PI3K, TH
85  2021 Updates on the understanding and management of thyroid eye disease. FDA, IgG, TED, TSHR
86  2020 Alpha-Particle Therapy for Multifocal Osteosarcoma: A Hypothesis. OST, PSMA
87  2020 Analyzing structural differences between insulin receptor (IR) and IGF1R for designing small molecule allosteric inhibitors of IGF1R as novel anti-cancer agents. IR
88  2020 Can Toxoplasma gondii Pave the Road for Dementia? T. gondii
89  2020 CD26 upregulates proliferation and invasion in keloid fibroblasts through an IGF-1-induced PI3K/AKT/mTOR pathway. EdU, KFs, mTOR
90  2020 Circulating Exosomes From Patients With Graves' Disease Induce an Inflammatory Immune Response. CD, GD, HSP60, IL, MyD88, PBMCs, TLR, WB
91  2020 CXCL14 Maintains hESC Self-Renewal through Binding to IGF-1R and Activation of the IGF-1R Pathway. BMAC, BRAK, GPCRs, hESCs, MIP-2gamma, RTK
92  2020 Deficits in hippocampal neurogenesis in obesity-dependent and -independent type-2 diabetes mellitus mouse models. AD, T2DM
93  2020 Development and preclinical evaluation of cixutumumab drug conjugates in a model of insulin growth factor receptor I (IGF-1R) positive cancer. ADCs, DAR
94  2020 Diagnostic Roles of Immunohistochemistry in Thymic Tumors: Differentiation between Thymic Carcinoma and Thymoma. Bcl-2, CEA, CK19, GLUT1, IHC, MUC1, TC, TdT, TM
95  2020 Doublecortin and IGF-1R protein levels are reduced in spite of unchanged DNA methylation in the hippocampus of aged rats. DG, mGluR5
96  2020 DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling. LV
97  2020 Exendin-4 induces a novel extended effect of ischemic tolerance via crosstalk with IGF-1R. Ex-4, GLP-1, MCAO
98  2020 High expression of SMYD3 indicates poor survival outcome and promotes tumour progression through an IGF-1R/AKT/E2F-1 positive feedback loop in bladder cancer. BC
99  2020 IGF-1R inhibition induces MEK phosphorylation to promote survival in colon carcinomas. p70S6K1
100  2020 IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer's Disease Transgenic Mouse Model. AD, APP, DMSO, PPP, PS1