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■ Abbreviation / Long Form : IkappaB / inhibitor of kappaB

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Total Number of Papers: 675
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Abbreviation:   IkappaB  (>> Co-occurring Abbreviation)
Long Form:   inhibitor of kappaB
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No. Year Title Co-occurring Abbreviation
2022 Carbenoxolone Ameliorates Allergic Airway Inflammation through NF-κB/NLRP3 Pathway in Mice. AR, BALF, CBX, IL, NF-kappaB, NLRP3, OVA
2022 Current Status of Experimental Animal Skin Flap Models: Ischemic Preconditioning and Molecular Factors. I/R, IL-6, IPC, NF-kappaB, TNF-alpha
2022 HDAC6 regulates NF-κB signalling to control chondrocyte IL-1-induced MMP and inflammatory gene expression. HDACi, IL, MMP
2022 HM-chromanone attenuates TNF-α-mediated inflammation and insulin resistance by controlling JNK activation and NF-κB pathway in 3T3-L1 adipocytes. HM-chromanone, IL, NF, pIRS, TNF
2022 IKKα plays a major role in canonical NF-κB signalling in colorectal cells. NF-kappaB
2022 Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside isolated from the flowers of Hosta plantaginea exerts anti-inflammatory activity via suppression of NF-κB, MAPKs and Akt pathways in RAW 264.7 cells. COX-2, ERK, IL-1beta, iNOS, JNK, KGG, LPS, MAPKs, NF-kappaB, NO, PGE2, TNF-alpha
2022 LncRNA Snhg5 Attenuates Status Epilepticus Induced Inflammation through Regulating NF-κΒ Signaling Pathway. IL, lncRNA SNHG5, LPS, NF-kappaB, SE, TNF
2022 N-(benzylidene)-2-((2-hydroxynaphthalen-1-yl)diazenyl)benzohydrazides (1-2) (NCHDH and NTHDH) attenuate DMBA-induced breast cancer via Nrf2/NF-κB/apoptosis signaling. Bax, Bcl-2, DMBA, ELISA, H and E, HO-1, MTT, Nrf2, PAS
2022 The protective effect of mangiferin on osteoarthritis: An in vitro and in vivo study. ACLT, IL-1beta, MMP, NF-kappaB, OA
10  2022 The Role of Nuclear Factor Kappa B (NF-κB) in the Immune Response against Parasites. NF-kappaB
11  2022 Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice. LC3, mTOR, NF-kappaB, PI3K, UA
12  2022 Xueshuantong injection alleviates cerebral microcirculation disorder in middle cerebral artery occlusion/reperfusion rats by suppressing inflammation via JNK mediated JAK2/STAT3 and NF-κB signaling pathways. IL, iNOS, JAK2, JNK, LPS, MCAO/R, MMP, NF-kappaB, STAT3, TEER, TNF, TTC, VCAM-1, XST, ZO-1
13  2022 [Bioinformatics analysis of IκB gene family expression in human lung adenocarcinoma]. LUAD, NFKBID, NFKBIZ
14  2021 A 2-Benzylmalonate Derivative as STAT3 Inhibitor Suppresses Tumor Growth in Hepatocellular Carcinoma by Upregulating beta-TrCP E3 Ubiquitin Ligase. beta-TrCP, EMT, HCC, IFN, ISRE, NF-kappaB, SH2, STAT3
15  2021 CK2 Down-Regulation Increases the Expression of Senescence-Associated Secretory Phenotype Factors through NF-kappaB Activation. IKK, IL, MMP, NF-kappaB, SASP
16  2021 Effects of glutamine on the IKK/IκB/NF-кB system in the enterocytes of turbot Scophthalmus maximus L. stimulated with soya-saponins. ---
17  2021 Enhancement of DUSP14 (dual specificity phosphatase 14) limits osteoarthritis progression by alleviating chondrocyte injury, inflammation and metabolic homeostasis. ACLT, AMPK, DUSP14, Dusp14, IL-1beta, OA, PGE2
18  2021 Ergosta-7, 9 (11), 22-trien-3beta-ol Interferes with LPS Docking to LBP, CD14, and TLR4/MD-2 Co-Receptors to Attenuate the NF-kappaB Inflammatory Pathway In Vitro and Drosophila. CD14, DEXA, GFP, LBP, LPS, MD-2, PI3K, TLR4
19  2021 Focal Adhesion Kinase Activity and Localization is Critical for TNF-α-Induced Nuclear Factor-κB Activation. ECs, FAK, NF-kappaB, RIPK1, TNF-alpha, TNFRC-I
20  2021 Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome. ASC, GSZD, IKK, IL, MAPKs, MCP, MSU, NF, NLRP3, TCM
21  2021 Hostaflavone A from Hosta plantaginea (Lam.) Asch. blocked NF-κB/iNOS/COX-2/MAPKs/Akt signaling pathways in LPS-induced RAW 264.7 macrophages. COX-2, ERK, HA, IL-1beta, iNOS, JNK, LPS, MAPKs, NF-kappaB, NO, PGE2, TNF-alpha
22  2021 IKBKB siRNA-Encapsulated Poly (Lactic-co-Glycolic Acid) Nanoparticles Diminish Neuropathic Pain by Inhibiting Microglial Activation. IKBKB, NF-kappaB, siRNA, SNL
23  2021 IκBα is required for full transcriptional induction of some NFκB-regulated genes in response to TNF in MCF-7 cells. IFFL, NF-kappaB, TNF
24  2021 Kaempferia parviflora extract inhibits TNF-α-induced release of MCP-1 in ovarian cancer cells through the suppression of NF-κB signaling. EOCs, IL-6, KP, LPS, MCP-1, NF-kappaB, OCCC, TAM, TNF-alpha
25  2021 Long non-coding RNA TUG1/microRNA-187-3p/TESC axis modulates progression of pituitary adenoma via regulating the NF-kappaB signaling pathway. lncRNAs, miRNAs, NF-kappaB, PA, TESC, TUG1
26  2021 mTOR inhibition as a possible pharmacological target in the management of systemic inflammatory response and associated neuroinflammation by lipopolysaccharide challenge in rats. HIF-1alpha, LPS, mTOR, NF-kappaB
27  2021 Novel Seleno-Aspirinyl Compound AS-10 Induces Apoptosis, G1 Arrest of Pancreatic Ductal Adenocarcinoma Cells, Inhibits Their NF-κB Signaling, and Synergizes with Gemcitabine Cytotoxicity. NF-kappaB, PDAC, TNF-alpha
28  2021 Plantanone C attenuates LPS-stimulated inflammation by inhibiting NF-κB/iNOS/COX-2/MAPKs/Akt pathways in RAW 264.7 macrophages. CCK-8, COX-2, ELISA, ERK, IL-1beta, iNOS, JNK, LPS, MAPKs, NF-kappaB, NO, PC, PGE2, TNF-alpha
29  2021 Samsum ant venom protects against carbon tetrachloride-induced acute spleen toxicity in vivo. CAT, MDA, SAV, TNF-alpha
30  2021 Suppression of phosphoinositide 3-kinase/phosphoinositide-dependent kinase-1/serum and glucocorticoid-induced protein kinase pathway. Bcl-2, CK, PDK1, PI3K
31  2021 Total Flavonoids of Rhizoma Drynariae Restore the MMP/TIMP Balance in Models of Osteoarthritis by Inhibiting the Activation of the NF-kappaB and PI3K/AKT Pathways. IL-1beta, NF-kappaB, OA, TFRD
32  2021 Vitamin D3/VDR inhibits inflammation through NF-kappaB pathway accompanied by resisting apoptosis and inducing autophagy in abalone Haliotis discus hannai. ASC, LDs, NF-kappaB, VDR
33  2020 Anti-Inflammatory Activity of Diterpenoids from Celastrus orbiculatus in Lipopolysaccharide-Stimulated RAW264.7 Cells. ERK, HRESIMS, JNK, MAPK, NMR, NO
34  2020 Anti-inflammatory and analgesic activities of indigo through regulating the IKKbeta/IkappaB/NF-kappaB pathway in mice. COX-2, IKK, IL-1beta, IL-6, iNOS, NF, PGE2, TNF-alpha
35  2020 Astilbe Chinensis ethanol extract suppresses inflammation in macrophages via NF-kappaB pathway. ACE, COX-2, IKK, IL, iNOS, LPS, NF-kappaB, NO, PGE2, TG, TNF-alpha
36  2020 Chrysin Inhibits NF-kappaB-Dependent CCL5 Transcription by Targeting IkappaB Kinase in the Atopic Dermatitis-Like Inflammatory Microenvironment. AD, NF-kappaB
37  2020 Copper induces hepatic inflammatory responses by activation of MAPKs and NF-kappaB signalling pathways in the mouse. AKP, ALB, ASK1, AST, COX-2, GGT, ICR, IL-1beta, IL-2, IL-8, iNOS, JNK, MAPKs, NF-kappaB, NO, p38 MAPK, PGE2, TBIL, TGF-beta
38  2020 Corynebacterium tuberculostearicum, a human skin colonizer, induces the canonical nuclear factor-kappaB inflammatory signaling pathway in human skin cells. C. t, HEKs, mRNA, NF-kappaB, PCR, SCCs, TLR2
39  2020 Costunolide improved dextran sulfate sodium-induced acute ulcerative colitis in mice through NF-kappaB, STAT1/3, and Akt signaling pathways. CTL, DSS, IFN-gamma, IL-1beta, iNOS, MPO, NF-kappaB, NO, TNF-alpha, UC
40  2020 Cryptotanshinone from Salvia miltiorrhiza Bunge (Danshen) inhibited inflammatory responses via TLR4/MyD88 signaling pathway. COX-2, CPT, ERK, HO-1, IKK, IL-6, iNOS, JNK, LPS, MAPK, MyD88, NF-kappaB, NO, NQO1, Nrf2, PI3K, TLR4, TNF-alpha
41  2020 Dimethyl fumarate suppresses metastasis and growth of melanoma cells by inhibiting the nuclear translocation of NF-kappaB. Bcl-xL, DMF, MMPs, NF-kappaB, VLAs
42  2020 Effect of GNAQ alteration on RANKL-induced osteoclastogenesis in human non-small-cell lung cancer. GNAQ, M-CSF, NF-kappaB, RANKL, TNF-alpha
43  2020 Effect of saccharin on inflammation in 3T3-L1 adipocytes and the related mechanism. COX-2, IL-1beta, IL-6, iNOS, LPS, MCP-1, NF-kappaB, NO, TNF-alpha
44  2020 Ethyl acetate extract of herpetospermum pedunculosum alleviates alpha-naphthylisothiocyanate-induced cholestasis by activating the farnesoid x receptor and suppressing oxidative stress and inflammation in rats. ANIT, FXR, IL-1beta, NF-kappaB
45  2020 Gastroprotective Effects of Fermented Lotus Root against Ethanol/HCl-Induced Gastric Mucosal Acute Toxicity in Rats. EtOH, FL, NF-kappaB
46  2020 Isodeoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber Linn., inhibits pro-inflammatory mediators' production through both NF-kappaB and AP-1 pathways in LPS-activated macrophages. AP-1, IDET, IL, iNOS, LPS, MCP-1, NF-kappaB, NO
47  2020 LXA4 protects against hypoxic-ischemic damage in neonatal rats by reducing the inflammatory response via the IkappaB/NF-kappaB pathway. HI, LXA4, NF-kappaB
48  2020 Mitochondrial membrane protein mitofusin 2 as a potential therapeutic target for treating free fatty acid-induced hepatic inflammation in dairy cows during early lactation. FFA, Mfn2, NF-kappaB, NLRP3, TNF-alpha
49  2020 Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility. ---
50  2020 Plumbagin inhibits tumor angiogenesis of gastric carcinoma in mice by modulating nuclear factor-kappa B pathway. ELISA, IKK, MVD, NF-kappaB, VEGF, VEGFR2
51  2020 PTP1B Inhibitory and Anti-inflammatory Properties of Constituents from Eclipta prostrata L. HO-1, LPS, NO, PTP
52  2020 Safrole-induced expression of proinflammatory responses is associated with phosphorylation of mitogen-activated protein kinase family and the nuclear factor-κB/inhibitor of κB pathway in macrophages. ERK, MAPK, NF
53  2020 Shikonin mitigates ovariectomy-induced bone loss and RANKL-induced osteoclastogenesis via TRAF6-mediated signaling pathways. CT, ERK, JNK, MAPK, NF-kappaB, RANK, RANKL, TRAF6
54  2020 Smilax guianensis Vitman Extract Prevents LPS-Induced Inflammation by Inhibiting the NF-kappaB Pathway in RAW 264.7 Cells. COX, IKK, IL, iNOS, LPS, SGE, TNF-alpha
55  2020 Sodium valproate attenuates the iE-DAP induced inflammatory response by inhibiting the NOD1-NF-kappaB pathway and histone modifications in bovine mammary epithelial cells. BMECs, BNBD5, HDAC, Hp, IL-1beta, IL-6, IL-8, LAP, NF-kappaB p65, NOD1, SAA3, TNF-alpha, VPA
56  2020 Terrein suppressed lipopolysaccharide-induced neuroinflammation through inhibition of NF-kappaB pathway by activating Nrf2/HO-1 signaling in BV2 and primary microglial cells. COX-2, HO, IL, iNOS, LPS, NF-kappaB, NO, Nrf2, PGE2
57  2020 The adaptor protein c-Cbl-associated protein (CAP) limits pro-inflammatory cytokine expression by inhibiting the NF-kappaB pathway. CAP, CVB3, LPS, TLR
58  2020 The effect of dihydropyrazines on lipopolysaccharide-stimulated human hepatoma HepG2 cells via regulating the TLR4-MyD88-mediated NF-kappaB signaling pathway. DHPs, IL-1beta, LPS-stimulated, MyD88, NF-kappaB, ROS, TLR4, TNF-alpha
59  2020 The Role and Therapeutic Potential of NF-kappa-B Pathway in Severe COVID-19 Patients. ARDS, COVID-19
60  2020 Treatment with catalpol protects against cisplatin-induced renal injury through Nrf2 and NF-kappaB signaling pathways. CP, HO-1, IL, iNOS, Keap1, Nrf2, TNF-alpha
61  2020 Young Yum pill inhibits inflammatory mediators and nuclear factor-kappa B signaling in lipopolysaccharide-stimulated RAW 264.7 macrophages. LPS, NF-kappaB, NO, PGE2, TNF-alpha, YYP
62  2020 [Study on chemical constituents of Dendrobium huoshanense stems and their anti-inflammatory activity]. ERK, IL-1beta, JNK, NF-kappaB, NO, TNF-alpha
63  2019 A chalcone derivative suppresses the induction of TSLP in mice and human keratinocytes and attenuates OVA-induced antibody production in mice. IgG1, Keap1, LPS, NF-kappaB, OVA, TSLP
64  2019 Adalimumab improves cognitive impairment, exerts neuroprotective effects and attenuates neuroinflammation in an Abeta1-40-injected mouse model of Alzheimer's disease. AD, BACE1, BDNF, IL, NF-kappaB, TNF-alpha
65  2019 Anti-Inflammatory Activity of beta-thymosin Peptide Derived from Pacific Oyster (Crassostrea gigas) on NO and PGE₂ Production by Down-Regulating NF-kappaB in LPS-Induced RAW264.7 Macrophage Cells. COX-2, IL-1beta, IL-6, iNOS, LPS, NF-kappaB, NO, TNF-alpha
66  2019 Anti-inflammatory effect of trans-4-methoxycinnamaldehyde from Etlingera pavieana in LPS-stimulated macrophages mediated through inactivation of NF-kappaB and JNK/c-Jun signaling pathways and in rat models of acute inflammation. LPS, MAPKs, MCD, NF-kappaB, NO, PGE2
67  2019 Anti-Inflammatory Effects of Canavalia gladiata in Macrophage Cells and DSS-Induced Colitis Mouse Model. COX-2, DSS, GSB, IFN-gamma, IL-1beta, IL-6, iNOS, NO, PGE2, RSB, TNF-alpha
68  2019 Anti-Inflammatory Effects of Shenfu Injection against Acute Lung Injury through Inhibiting HMGB1-NF-kappaB Pathway in a Rat Model of Endotoxin Shock. ALI, HMGB1, IL, IL-1beta, MAP, SFI, TNF
69  2019 Anti-inflammatory Potential of Saponins from Aster tataricus via NF-kappaB/MAPK Activation. COX-2, iNOS, LPS, NO
70  2019 Astragaloside IV alleviates the symptoms of experimental ulcerative colitis in vitro and in vivo. ASI, IL-1beta, IL-6, LPS, MPO, NO, TNF-alpha, UC
71  2019 Benzoylaconitine Inhibits Production of IL-6 and IL-8 via MAPK, Akt, NF-kappaB Signaling in IL-1beta-Induced Human Synovial Cells. BAC, IL, MAPK, NF-kappaB, RA
72  2019 Differences in anti-inflammatory effect of immature and mature of Rubus coreanus fruits on LPS-induced RAW 264.7 macrophages via NF-kappaB signal pathways. COX, DPPH, IL, iNOS, LPS, NF, NO, RF
73  2019 Effective fraction of Bletilla striata reduces the inflammatory cytokine production induced by water and organic extracts of airborne fine particulate matter (PM2.5) in vitro. EFB, ERK, JNK, MAPK, NF-kappaB
74  2019 Hepatic nuclear factor kappa B signaling pathway and NLR family pyrin domain containing 3 inflammasome is over-activated in ketotic dairy cows. AST, BHB, CASP1, NF-kappaB, NLRP3, TNF
75  2019 IkappaBzeta facilitates protective immunity against Salmonella infection via Th1 differentiation and IgG production. RASV
76  2019 IKKbeta Inhibitor IMD-0354 Attenuates Radiation Damage in Whole-body X-Irradiated Mice. NF-kappaB
77  2019 IKKepsilon-like plays an important role in the innate immune signaling of the Pacific oyster (Crassostrea gigas). IFN, IKKepsilon, IRFs, NF-kappaB, ORF
78  2019 Kaempferol‑3‑O‑beta‑rutinoside suppresses the inflammatory responses in lipopolysaccharide‑stimulated RAW264.7 cells via the NF‑kappaB and MAPK pathways. LPS, MAPK
79  2019 Loss of Annexin A5 expression attenuates the lipopolysaccharide-induced inflammatory response of rat alveolar macrophages. ALI, AMs, AnxA5, LPS, mRNAs, NF-kappaB, Nrf2, qRT-PCR, TNF-alpha
80  2019 Mechanisms underlying isoliquiritigenin-induced apoptosis and cell cycle arrest via ROS-mediated MAPK/STAT3/NF-kappaB pathways in human hepatocellular carcinoma cells. ERK, HCC, ISL, JNK, MAPK, NAC, NF-kappaB, ROS, STAT3
81  2019 Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO. NF-kappaB, ROS
82  2019 Modulation of oxidative-nitrosative stress and inflammatory response by rapamycin in target and distant organs in rats exposed to hindlimb ischemia-reperfusion: the role of mammalian target of rapamycin. I/R, mTOR, NF-kappaB, rpS6
83  2019 Phospholipase Cepsilon plays a crucial role in neutrophilic inflammation accompanying acute lung injury through augmentation of CXC chemokine production from alveolar epithelial cells. AECs, ALI, LPS, NF-kappaB, PKD, PLCepsilon
84  2019 Role of ANTXR1 in the regulation of RANKL-induced osteoclast differentiation and function. ANTXR1, BMMs, JNK, MMP-9, NFATc1, PLCgamma2, RANKL, VEGFA
85  2019 Suppression of Carnosine on Adhesion and Extravasation of Human Colorectal Cancer Cells. NF-kappaB, RHO, VE-cadherin
86  2019 TACI expression and plasma cell differentiation are impaired in the absence of functional IkappaBNS. LPS, TACI, TI, WT
87  2019 Taraxasterol suppresses inflammation in IL-1beta-induced rheumatoid arthritis fibroblast-like synoviocytes and rheumatoid arthritis progression in mice. ASC, CIA, HFLS-RA, IKK, IL, MMPs, NF-kappaB, NLRP3, RA, TAK1, TAR, TNF-alpha
88  2019 Vibration enhances osteoclastogenesis by inducing RANKL expression via NF-kappaB signaling in osteocytes. NF-kappaB, OPG
89  2018 3‑Bromo‑5‑(ethoxymethyl)‑1,2‑benzenediol inhibits LPS-induced pro-inflammatory responses by preventing ROS production and downregulating NF-kappaB in vitro and in a zebrafish model. COX-2, iNOS, LPS, NF, NO, ROS
90  2018 Anti-Inflammatory Effects of Hypophyllanthin and Niranthin Through Downregulation of NF-kappaB/MAPKs/PI3K-Akt Signaling Pathways. COX-2, ERK, HYP, IL-1beta, JNK, MAPKs, NF-kappaB, NIR, PGE2, PI3K-Akt, TNF-alpha
91  2018 BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappaB and Activating PKA/CREB. CNS, CREB, IKK, LPS, NF-kappaB, PKA
92  2018 BMAL1 regulates balance of osteogenic-osteoclastic function of bone marrow mesenchymal stem cells in type 2 diabetes mellitus through the NF-kappaB pathway. BMAL1, BMSCs, p-p65, RANKL/OPG, T2DM
93  2018 Butyrolactone-I from Coral-Derived Fungus Aspergillus terreus Attenuates Neuro-Inflammatory Response via Suppression of NF-kappaB Pathway in BV-2 Cells. COX-2, ELISA, IL-1beta, iNOS, LPS, NF-kappaB, NO
94  2018 Cyanidin-3-o-beta-Glucoside Induces Megakaryocyte Apoptosis via PI3K/Akt- and MAPKs-Mediated Inhibition of NF-kappaB Signalling. Fas, IKK, MAPK, NF-kappaB, PI3K
95  2018 Desoxo-narchinol A and Narchinol B Isolated from Nardostachys jatamansi Exert Anti-neuroinflammatory Effects by Up-regulating of Nuclear Transcription Factor Erythroid-2-Related Factor 2/Heme Oxygenase-1 Signaling. COX, ERK, GSK-3beta, HO-1, iNOS, LPS, NF, NO, Nrf2, PGE2
96  2018 Enhanced interaction between SEC2 mutant and TCR Vbeta induces MHC II-independent activation of T cells via PKCtheta/NF-kappaB and IL-2R/STAT5 signaling pathways. APCs, MHC-II, PKCtheta, TCR
97  2018 Fordin: A novel type I ribosome inactivating protein from Vernicia fordii modulates multiple signaling cascades leading to anti-invasive and pro-apoptotic effects in cancer cells invitro. MMP, NF, RIP
98  2018 Hepatoprotective effect of chiisanoside from Acanthopanax sessiliflorus against LPS/D-GalN-induced acute liver injury by inhibiting NF-kappaB and activating Nrf2/HO-1 signaling pathways. ALT, AST, CAT, CSS, HO-1, MDA, NF-kappaB, Nrf2, SOD
99  2018 Icariside II attenuates myocardial fibrosis by inhibiting nuclear factor-kappaB and the TGF-beta1/Smad2 signalling pathway in spontaneously hypertensive rats. ICS II, IL-1beta, NF-kappaB, SHRs, TGF-beta1, TNF-alpha
100  2018 Inflammatory mechanism of Rumenitis in dairy cows with subacute ruminal acidosis. IL-1beta, IL-6, JNK, LPS, MAPK, NF-kappaB, SARA, TNF-alpha