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■ Abbreviation / Long Form : MUC5AC / mucin 5AC

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Total Number of Papers: 214
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Abbreviation:   MUC5AC  (>> Co-occurring Abbreviation)
Long Form:   mucin 5AC
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No. Year Title Co-occurring Abbreviation
2022 Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease. ATP, COPD
2022 Anti-EGFR Single-Chain Fv Antibody Fragment Displayed on the Surface of Ferritin H-Chain Protein Nanoparticle for Asthma Therapy. anti-EGFR scFv, EGFR, HDM, LPS, OVA
2022 Autocrine TGF-alpha is associated with Benzo(a)pyrene-induced mucus production and MUC5AC expression during allergic asthma. AB-PAS, AhR, BALF, BaP, OVA, TGF
2022 Black Ginseng Extract Suppresses Airway Inflammation Induced by Cigarette Smoke and Lipopolysaccharides In Vivo. BGE, CS, IL, LPS, MCP, ROS, TAK, TNF
2022 Characterization of mucin gene expression and goblet cell proportion in inflammatory colorectal polyps in miniature dachshunds. ICRPs, MUC2
2022 Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways. ATF6, CGA, CHOP, ER, GRP78, MLCK, p-MLC, p-MYPT1, ROCK1, TEER, TFF3
2022 Cholesterol crystals activate NLRP3 inflammasomes and promote gallstone formation by increasing mucin secretion. ASC, IL-1b, NLRC4, NLRP3
2022 Compound K ameliorates airway inflammation and mucus secretion through the regulation of PKC signaling in vitro and in vivo. CK, COPD, CS, PMA, TNF-alpha
2022 Effects of 4-DAMP on allergic rhinitis in guinea pigs and its potential mechanism. 4-DAMP, AR, EGFR, ELISA, IB, IgE, MMP-9, mRNA, NLF, OVA, qRT-PCR
10  2022 Effects of Wood Smoke Constituents on Mucin Gene Expression in Mice and Human Airway Epithelial Cells and on Nasal Epithelia of Subjects with a Susceptibility Gene Variant in Tp53. AECs, CS, TP53, WS
11  2022 Expression of Mucins in Different Entities of Salivary Gland Cancer: Highest Expression of Mucin-1 in Salivary Duct Carcinoma : Mucin-1 - highest expression in Salivary Duct Carcinoma. MUC1, MUC16, SGC
12  2022 Fluorescent Anti-MUC5AC Brightly Targets Pancreatic Cancer in a Patient-derived Orthotopic Xenograft. PDOX
13  2022 HDAC4 depletion ameliorates IL-13-triggered inflammatory response and mucus production in nasal epithelial cells via activation of SIRT1/NF-κB signaling. AR, HDAC4, HNECs, IgE, IL-13, NF-kappaB, SIRT1
14  2022 HNE Induces the Hyperexpression of MUC5AC in Chronic Rhinosinusitis With Nasal Polyps by Activating the TRAF6/Autophagy Regulatory Axis. ATG5, BECN1, CRSwNP, HNE, TRAF6
15  2022 Home Dust Mites Promote MUC5AC Hyper-Expression by Modulating the sNASP/TRAF6 Axis in the Airway Epithelium. AHR, HDMs, sNASP, TLR, TRAF6
16  2022 MicroRNAs Associated with Chronic Mucus Hypersecretion in COPD Are Involved in Fibroblast-Epithelium Crosstalk. CMH, COPD, miRNAs, PBECs
17  2022 Mucin 5AC expression is common but unrelated to tumor progression in pancreatic adenocarcinoma. TMA
18  2022 Mucin 5AC-Mediated CD44/ITGB1 Clustering Mobilizes Adipose-Derived Mesenchymal Stem Cells to Modulate Pancreatic Cancer Stromal Heterogeneity. ADMSCs, KC, PC
19  2022 NICD3 regulates the expression of MUC5AC and MUC2 by recruiting SMARCA4 and is involved in the differentiation of mucinous colorectal adenocarcinoma. CRC, MCA, MUC2, NOTCH3
20  2022 Processed product (Pinelliae Rhizoma Praeparatum) of Pinellia ternata (Thunb.) Breit. Alleviates the allergic airway inflammation of cold phlegm via regulation of PKC/EGFR/MAPK/PI3K-AKT signaling pathway. AQP5, BALF, CA, IHC, OVA, PRP
21  2022 Reineckia carnea Alleviates the Production of Inflammatory Cytokines and MUC5AC in Rats with Chronic Obstructive Pulmonary Disease. COPD, COX-2, ELISA, IL, PGE2, qPCR, RC, TLR4
22  2022 Serum MUC5AC protein levels are correlated with the development and severity of connective tissue disease-associated pulmonary interstitial lesions. CTD-ILD, MUC5B, PM/DM, pSS, SSc
23  2022 Tumor necrosis factor-α promotes airway mucus hypersecretion by repressing miR-146a-5p and miR-134-5p levels in human airway epithelial cells. CCK-8, COPD, MAPK, miRNAs, qPCR
24  2022 Type IV collagen reduces MUC5AC secretion in the lungs of ovalbumin-sensitized mice. ECM, ERK, OVA
25  2022 Vegetable glycerin e-cigarette aerosols cause airway inflammation and ion channel dysfunction. ALI, CFTR, e-cig, HBECs, IL-6, IL-8, MMP-9, PG, TGF-beta1, VG
26  2022 [Bufei Yishen formula attenuates cigarette smoke extract-induced airway mucus hypersecretion by regulating Notch signaling pathway]. BYF, CSE, ELISA, Hes1, MTT, qPCR
27  2022 [Mechanism of Xiaoqinglong Decoction and Qingqi Huatan Pills in improving pathological airway mucus based on nuclear factor-κB/microRNA-494 signaling regulation of mucin 5AC and cystic fibrosis transmembrane conductance regulator]. CFTR, ELISA, IkappaB, IL-1beta, MTT, PDTC, RT-qPCR, TNF-alpha
28  2021 A pilot study of spray cryotherapy effects on airway secretions. BALF, ELISA, SCT
29  2021 Alnus hirsuta (Spach) Rupr. Attenuates Airway Inflammation and Mucus Overproduction in a Murine Model of Ovalbumin-Challenged Asthma. OVA, p65NF-kappaB, TNF
30  2021 Alteration of Colonic Mucin Composition and Cytokine Expression in Acute Swine Dysentery. Bhyo, DDGS, MUC2, SD
31  2021 Amygdalin Attenuates Airway Epithelium Apoptosis, Inflammation, and Epithelial-Mesenchymal Transition through Restraining the TLR4/NF-kappaB Signaling Pathway on LPS-Treated BEAS-2B Bronchial Epithelial Cells. CVA, IL, p-IkappaBalpha, p-p65, SMA, TNF
32  2021 Apremilast mitigates interleukin (IL)-13-induced inflammatory response and mucin production in human nasal epithelial cells (hNECs). AP-1, AR, CSF2, HNECs, IL, JNK, MDA, NF-kappaB, PDE4, ROS
33  2021 Atractylodin attenuates the expression of MUC5AC and extracellular matrix in lipopolysaccharide-induced airway inflammation by inhibiting the NF-kappaB pathway. ATR, IL, LPS
34  2021 Bee Venom Prevents Mucin 5AC Production through Inhibition of AKT and SPDEF Activation in Airway Epithelia Cells. BV, FOXA2, PI3K, SPDEF
35  2021 Benzo(a)pyrene induces MUC5AC expression through the AhR/mitochondrial ROS/ERK pathway in airway epithelial cells. AhR, BaP, CRE
36  2021 Decreased Gastric Gland Mucin-specific O-glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours. MUC2, MUC6, OPMTs
37  2021 Effect of Korean Red Ginseng and Rg3 on Asian Sand Dust-Induced MUC5AC, MUC5B, and MUC8 Expression in Bronchial Epithelial Cells. ASD, KRG, MAPK, NF-kappaB
38  2021 Establishment of a Potential Serum Biomarker Panel for the Diagnosis and Prognosis of Cholangiocarcinoma Using Decision Tree Algorithms. CA19-9, CART, CCA, DT, S100A9, TGF-beta1
39  2021 Euxanthone inhibits lipopolysaccharide-induced injury, inflammatory response, and MUC5AC hypersecretion in human airway epithelial cells by the TLR4/MyD88 pathway. AECs, ELISA, IL, KEGG, LDH, LPS, MCP-1, MyD88, TLR4, TUNEL
40  2021 Gene expression profiles of pro-inflammatory mediators in the conjunctiva of patients with epiblepharon. IL, MMP-9
41  2021 Hulless barley and beta-glucanase affect ileal digesta soluble beta-glucan molecular weight and digestive tract characteristics of coccidiosis-vaccinated broilers. BGase, HB, IL-6, MCT1, MUC2, SCFA
42  2021 Influence of o,p'-DDT on MUC5AC expression via regulation of NF-kappaB/AP-1 activation in human lung epithelial cells. AP-1, COPD, NF-kappaB, o,p'-DDT
43  2021 Integrin beta1 subunit regulates cellular and secreted MUC5AC and MUC5B production in NCI-H292 human lung epithelial cells. ERK, MUC5B
44  2021 Less airway inflammation and goblet cell metaplasia in an IL-33-induced asthma model of leptin-deficient obese mice. AHR, BALF, KC
45  2021 Modeling Airway Dysfunction in Asthma Using Synthetic Mucus Biomaterials. HAE
46  2021 MUC5AC Expression in Various Tumor Types and Nonneoplastic Tissue: A Tissue Microarray Study on 10 399 Tissue Samples. ---
47  2021 MUC5AC expression is linked to mucinous/endometroid subtype, absence of nodal metastasis and mismatch repair deficiency in ovarian cancer. dMMR
48  2021 Role for Mucin-5AC in Upper and Lower Airway Pathogenesis in Mice. RSV
49  2021 SOX9 inactivation affects the proliferation and differentiation of human lung organoids. SCGB1A1, SOX9, WT
50  2021 Telmisartan mitigates lipopolysaccharide (LPS)-induced production of mucin 5AC (MUC5AC) through increasing suppressor of cytokine signaling 1 (SOCS1). ALI, IL-6, LDH, LPS, NF-kappaB, SOCS1, TGF, TNF-alpha
51  2021 The protective effects of Omarigliptin against Lipopolysaccharide (LPS)- induced inflammatory response and expression of mucin 5AC (MUC5AC) in human bronchial epithelial cells. AMP, COPD, DPP-4, IL-12, IL-1beta, LPS, MCP-1, ROS, SOCS1
52  2021 Understanding the Clinical Impact of MUC5AC Expression on Pancreatic Ductal Adenocarcinoma. mAb
53  2021 [Electroacupuncture improves lung function by suppressing mucin-5AC mediated EGFR-p38MAPK signaling and inflammation reaction in chronic obstructive pulmonary disease rats]. BALF, COPD, EA, EGFR, FEV, FVC, IL-8, LPS, p38 MAPK, TGF-alpha, TNF-alpha
54  2020 Altered mucins and aquaporins indicate dry eye outcome in patients undergoing Vitreo-retinal surgery. AQP4, GCD, VR
55  2020 Analysis the effect of miR-141-3p/HMGB1 in LPS-induced mucus production and the apoptosis in nasal epithelial cells. AR, HMGB1, IgE, LPS, miR-141-3p, NECs
56  2020 Assessment of mucin-related gene alterations following treatment with rebamipide ophthalmic suspension in Sjogren's syndrome-associated dry eyes. MUC16, SPDEF, SSDE
57  2020 Biliary intraductal tubule-forming neoplasm: a whole exome sequencing study of MUC5AC-positive and -negative cases. ITPNs
58  2020 Changes in Tracheal Respiratory Mucosa After Thyroidectomy: A Rat Model. KRT5
59  2020 circARRDC3 contributes to interleukin‑13‑induced inflammatory cytokine and mucus production in nasal epithelial cells via the miR‑375/KLF4 axis. AR, circARRDC3, circRNA, KLF4, miR
60  2020 Effects of Amniotic Membrane Extract on the Hyperplastic Response of the Middle Ear Mucosa in a Bacterially-Induced Otitis Media Rat Model: A Preliminary Study. AME, ICC, IL-10, ME, NTHi, OM, PCR, TNF-alpha
61  2020 Efficacy of Budesonide Nasal Spray on Neutrophilic Chronic Rhinosinusitis with Nasal Polyps: A Combined Clinical and Experimental Study. CRSwNP, EAs, IFN, IL, MPO, NPs, SNOT, VAS
62  2020 Elevated MUC5AC expression is associated with mismatch repair deficiency and proximal tumor location but not with cancer progression in colon cancer. pMMR
63  2020 Evaluation of serum MUC5AC in combination with CA19-9 for the diagnosis of pancreatic cancer. CA19-9, PC
64  2020 Exposure to Traffic-Related Particulate Matter 2.5 Triggers Th2-Dominant Ocular Immune Response in a Murine Model. DCs, DED, LNs, PM, Th1, Th2, TNF
65  2020 Knockdown of lncRNA ANRIL suppresses the production of inflammatory cytokines and mucin 5AC in nasal epithelial cells via the miR-15a-5p/JAK2 axis. AR, GM-CSF, HNECs, miR
66  2020 Lindera obtusiloba Attenuates Oxidative Stress and Airway Inflammation in a Murine Model of Ovalbumin-Challenged Asthma. AP, HO-1, LOL, MAPKs, NF-kappaB, NQO1, Nrf2, OVA, TNF
67  2020 Mechanism of azithromycin in airway diseases. AZM, IL, MAPK
68  2020 Molecular mechanism underlying miR‑130b‑Sp1 transcriptional regulation in LPS‑induced upregulation of MUC5AC in the bile duct epithelium. LPS, Sp1
69  2020 Monocyte chemotactic protein-inducing protein 1 negatively regulating asthmatic airway inflammation and mucus hypersecretion involving gamma-aminobutyric acid type A receptor signaling pathway in vivo and in vitro. GABAAR, IL, MCPIP1, OVA, TSLP
70  2020 MUC5AC enhances tumor heterogeneity in lung adenocarcinoma with mucin production and is associated with poor prognosis. ---
71  2020 Pepsin exposure in a non-acidic environment upregulates mucin 5AC (MUC5AC) expression via matrix metalloproteinase 9 (MMP9)/nuclear factor kappaB (NF-kappaB) in human airway epithelial cells. GR, HNEpCs, MMP-9, NF-kappaB, RT-PCR, siRNA
72  2020 Protective role of overexpressed MUC5AC against fibrosis in MHV-68-induced combined pulmonary fibrosis and emphysema mouse model. BALF, CPFE, IL-13, MHV-68, TGF-beta1
73  2020 Pulmonary Mycosis Drives Forkhead Box Protein A2 Degradation and Mucus Hypersecretion through Activation of the Spleen Tyrosine Kinase-Epidermal Growth Factor Receptor-AKT/Extracellular Signal-Regulated Kinase 1/2 Signaling. FOXA2, MUC5B
74  2020 Qingfei oral liquid alleviates airway hyperresponsiveness and mucus hypersecretion via TRPV1 signaling in RSV-infected asthmatic mice. AHR, OVA, QF, RSV, TRPV1
75  2020 Secretory Mucin 5AC Promotes Neoplastic Progression by Augmenting KLF4-Mediated Pancreatic Cancer Cell Stemness. CSC, PanIN-I
76  2020 Suhuang Antitussive Capsules-Ameliorative Effects on LPS-Induced Sputum Obstruction in Mice Through Promoting HGF Secretion. SH capsule
77  2020 The Cosmc-mediated effects of neutrophil elastase on T antigen expression in BEAS-2B cells. NE, PI3K
78  2020 The Effect of Different Water Extracts from Platycodon grandiflorum on Selected Factors Associated with Pathogenesis of Chronic Bronchitis in Rats. CRP
79  2019 Carbocisteine inhibits the expression of Muc5b in COPD mouse model. CS, MUC5B
80  2019 Characterization of the human mucin 5AC promoter and its regulation by the histone acetyltransferase P300. HATs, PCR
81  2019 Cucurbitacin E ameliorates lipopolysaccharide-evoked injury, inflammation and MUC5AC expression in bronchial epithelial cells by restraining the HMGB1-TLR4-NF-kappaB signaling. CuE, HMGB1, LPS
82  2019 DFSG, a novel herbal cocktail with anti-asthma activity, suppressed MUC5AC in A549 cells and alleviated allergic airway hypersensitivity and inflammatory cell infiltration in a chronic asthma mouse model. Der p
83  2019 Differentially expressed genes ASPN, COL1A1, FN1, VCAN and MUC5AC are potential prognostic biomarkers for gastric cancer. ASPN, COL1A1, DEGs, FN1, GC, GO, VCAN
84  2019 EGFR monoclonal antibody panitumumab inhibits chronic proliferative cholangitis by downregulating EGFR. CPC, EGFR, mTOR, Pani
85  2019 Esculetin inhibits histamine-induced expression of inflammatory cytokines and mucin in nasal epithelial cells. AR, HNEpC
86  2019 Hydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor. AhR, CAPs, FA, MDA, PAS
87  2019 Increase in secreted airway mucins and partial Muc5b STAT6/FoxA2 regulation during Pneumocystis primary infection. COPD
88  2019 Inhibiting the Notch signaling pathway suppresses Th17-associated airway hyperresponsiveness in obese asthmatic mice. AHR, DIO, GSI, Hes1, HFD, IL, NICD, OVA, RORgammat
89  2019 MicroRNA-155 regulates lipopolysaccharide-induced mucin 5AC overproduction via a suppressor of cytokine signaling 1-mediated mechanism in human bronchial epithelial cells. LPS, SOCS1, TLR
90  2019 MicroRNA-378 inhibits the development of smoking-induced COPD by targeting TNF-alpha. CSE, ELISA, HBE, qRT-PCR, TNF-alpha
91  2019 Mucinous colorectal adenocarcinoma: clinical pathology and treatment options. CRC, MSI, MUC2
92  2019 Obtusifolin isolated from the seeds of Cassia obtusifolia regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via affecting NF-kappaB pathway. EGF, NF-kappaB, PMA, TNF-alpha
93  2019 The role of the XBP-1/AGR2 signaling pathway in the regulation of airway Mucin5ac hypersecretion under hypoxia. AGR2, HIF-1alpha
94  2019 Type IV collagen reduces mucin 5AC secretion in three-dimensional cultured human primary airway epithelial cells. ECM, ERK
95  2018 Chronic E-Cigarette Exposure Alters the Human Bronchial Epithelial Proteome. PG/VG
96  2018 Curcumin Inhibits Lipopolysaccharide-Induced Mucin 5AC Hypersecretion and Airway Inflammation via Nuclear Factor Erythroid 2-Related Factor 2. BALF, CUR, LPS, Nrf2, siRNA
97  2018 Curcumin suppresses MUC5AC production via interfering with the EGFR signaling pathway. EGF, EGFR, STAT3
98  2018 Effects of 1,25-Dihydroxyvitamin D3 on the Prevention of Chronic Obstructive Pulmonary Disease (COPD) in Rats Exposed to Air Pollutant Particles Less than 2.5 Micrometers in Diameter (PM2.5). COPD, JNK1, PM2.5, RT-PCR, TUNEL
99  2018 Frequency-dependent airway hyperresponsiveness in a mouse model of emphysema and allergic inflammation. ACO, AHR, BALF, COPD, IL, OVA, SP-D, WT
100  2018 Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholangitis. BTC, CA19-9, CCA, GGT, IL-6, PKM2, PSC