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■ Abbreviation / Long Form : MZR / mizoribine

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Total Number of Papers: 125
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Abbreviation:   MZR  (>> Co-occurring Abbreviation)
Long Form:   mizoribine
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No. Year Title Co-occurring Abbreviation
2021 Conversion from mycophenolate mofetil to mizoribine in the early stages of BK polyomavirus infection could improve kidney allograft prognosis: a single-center study from China. BKPyV, BKPyVAN, Hb, MMF, PLT, PRA, SCr, UA, WBC
2021 Effectiveness and safety of mizoribine for the treatment of IgG4-related disease: a retrospective cohort study. GC, IgG4-RD
2020 Comparative Study of Mizoribine and Mycophenolate Mofetil Combined with a Calcineurin Inhibitor-Based Immunosuppressive Regimen in Patients with Alternative Donor Hematopoietic Cell Transplantation. CMV, CNI, GVHD, HCT, HR, NRM, OR
2020 Comparison of Treatment Effect and Tolerance of the Topical Application of Mizoribine and Cyclosporine A in a Mouse Dry Eye Model. CsA, DS, IL, MMP-9, PBS
2020 Effect of mizoribine pulse therapy in adult membranous nephropathy. CPM, MN
2020 Efficacy and Safety of a Quadruple Regimen Compared with Triple Regimens in Patients with Mycophenolic Acid-Related Gastrointestinal Complications After Renal Transplantation: A Short-Term Single-Center Study. CMV, EC-MPS, eGFR, GI, GSRS, HLA, MPA
2020 Genetic and clinical determinants of mizoribine pharmacokinetics in renal transplant recipients. PK, SCr
2020 Membranoproliferative glomerulonephritis related to a streptococcal infection in a girl with IgA deficiency: a case report. MPGN, PSL
2019 A case of anti-neutrophil cytoplasmic antibody-associated vasculitis with anti-glomerular basement membrane antibodies that was successfully treated with mizoribine as a safe and effective remission maintenance therapy with prednisolone and plasma exchange. ANCA, anti-GBM, MPO, mPSL, PE, PSL
10  2019 Assessment of factors associated with mizoribine responsiveness in children with steroid-dependent nephrotic syndrome. AUC0-4, BW, SDNS
11  2019 Effectiveness of cryofiltration and mizoribine combination with oral steroid therapy in a patient with membranoproliferative glomerulonephritis due to essential cryoglobulinemia. MPGN, PSL
12  2019 Efficacy and Safety of Mizoribine Combined With Tacrolimus in Living Donor Kidney Transplant Recipients: 3-Year Results by a Chinese Single Center Study. AR, eGFR, LDKT, MMF
13  2019 Hyperuricemia in Living Donor Kidney Transplantation Patients During Mizoribine Administration Caused Mainly by Changes in Kidney Function. SCr, serum beta2-MG, serum Cys-C
14  2019 Long-term Survival Analysis of Kidney Transplant Recipients Receiving Mizoribine as a Maintenance Immunosuppressant: A Single-Center Study. ---
15  2019 Mizoribine is as Effective as Methotrexate for the Treatment of Polymyalgia Rheumatica: A Retrospective Case Series Analysis. MTX
16  2019 Usefulness of mizoribine administration in children with frequently relapsing nephrotic syndrome, and the relationship between pharmacokinetic parameters and efficacy: a multicenter prospective cohort study in China. FRNS
17  2018 Acute Inflammatory Syndrome Paradoxically Induced by De Novo Purine Inhibitors Synthesis Before Renal Transplantation: A Case Report and Review of the Literature. EVL, MMF, TAC
18  2018 Conversion From Mycophenolates to Mizoribine Is Associated WithLower BK Virus Load in Kidney Transplant Recipients: AProspective Study. BKVAN
19  2018 Positive effects of single-daily high-dose mizoribine therapy after cyclophosphamide in young children with steroid-dependent nephrotic syndrome. CPM, SDNS
20  2018 Prediction of mizoribine pharmacokinetic parameters by serum creatinine in renal transplant recipients. Ccr, MRT, PK, SCr, V/F
21  2018 Uptake and metabolism of mizoribine, an immunosuppressant, in L5178Y-R mouse lymphoma cells invitro and peripheral blood mononuclear cells of rats and kidney transplant recipients invivo. MZRP, PBMCs
22  2017 Comparison of Mizoribine and Mycophenolate Mofetil With a Tacrolimus-Based Immunosuppressive Regimen in Living-Donor Kidney Transplantation Recipients: A Retrospective Study in China. GI, LDKT, MMF
23  2017 Efficacy and safety of adding mizoribine to standard treatment in patients with immunoglobulin A nephropathy: A randomized controlled trial. IgA
24  2017 Maintenance treatment using the purine-synthesis inhibitor mizoribine in a patient with relapsing thrombotic thrombocytopenic purpura. PE, TTP
25  2017 Mizoribine Synchronized Methotrexate Therapy should be Considered when Treating Rheumatoid Arthritis Patients with an Inadequate Response to Various Combination Therapies. DAS28, DMARDs, MTX, RA, SDAI
26  2017 Topical Application of Mizoribine Suppresses CD4+ T-cell-Mediated Pathogenesis in Murine Dry Eye. DED, DS, MMP, OGD
27  2016 Comparison of steroid-pulse therapy and combined with mizoribine in IgA nephropathy: a randomized controlled trial. Cr, IgAN
28  2016 Effectiveness of the Combination of Everolimus and Tacrolimus WithHigh Dosage of Mizoribine for Living Donor-Related Kidney Transplantation. CNI, EVR, TAC
29  2016 Efficacy and Safety of High-Dose Mizoribine Combined With Cyclosporine, Basiliximab, and Corticosteroids in Renal Transplantation: A Japanese Multicenter Study. CMV, MMF
30  2016 Influence of cyclosporine A on glomerular growth and the effect of mizoribine and losartan on cyclosporine nephrotoxicity in young rats. CsA, LSAR, OPN
31  2016 Mizoribine therapy combined with steroids and mizoribine blood concentration monitoring for idiopathic membranous nephropathy with steroid-resistant nephrotic syndrome. CR, IMN, PPK, PSL, SRNS
32  2016 Safety and efficacy of mizoribine treatment in nephrotic syndrome complicated with hepatitis B virus infection: a clinical study. ALB, HBV, TG
33  2016 The effectiveness of new triple combination therapy using synthetic disease-modifying anti-rheumatic drugs with different pharmacological function against rheumatoid arthritis: the verification by an in vitro and clinical study. MTX, RA, TAC
34  2016 The true distribution volume and bioavailability of mizoribine in children with chronic kidney disease. PPK, PSPKD, Vd
35  2015 Mizoribine in the treatment of pediatric-onset glomerular disease. ---
36  2015 Population pharmacokinetics of mizoribine in pediatric patients with kidney disease. ---
37  2014 A case of microscopic polyangiitis in an elderly patient presenting predominantly with cholecystitis successfully treated with mizoribine. MPA, MPO-ANCA
38  2014 Comparative efficacy and safety of mizoribine with mycophenolate mofetil for Asian renal transplantation--a meta-analysis. MMF
39  2014 Efficacy of mizoribine-tacrolimus-based induction therapy for pediatric lupus nephritis. LN, PDN, TAC
40  2014 Mizoribine inhibits the proliferation of renal stem/progenitor cells by G1/S arrest during renal regeneration. CPA, ECIS, I/R
41  2014 Mizoribine versus mycophenolate mofetil or intravenous cyclophosphamide for induction treatment of active lupus nephritis. AEs, ANOVA, CYC, LN, MMF
42  2014 Mizoribine-induced severe hyperglycemia in a patient with microscopic polyangiitis. CPR, GR, GTP, PSL
43  2014 Study of mizoribine therapy in elderly patients with membranous nephropathy: comparison with patients not receiving mizoribine. MN, MZR-G, PSL
44  2014 The efficacy of mizoribine for the treatment of rheumatoid arthritis and its correlation with renal function. CysC, RA
45  2014 Usefulness and safety of high-dose mizoribine on ABO-incompatible living related kidney transplantation using anti-CD20 and anti-CD25 antibodies without splenectomy: 3-year results. ABOi, CNI, LDKT
46  2013 A Japanese multicenter study of high-dose mizoribine combined with cyclosporine, basiliximab, and corticosteroid in renal transplantation (the fourth report). ARE, BXM, CMV, ROC, STR
47  2013 Excellent results of high-dose mizoribine combined with cyclosporine, basiliximab, and corticosteroids in renal transplant recipients--4-year results. MMF
48  2013 Influence of serum uric acid levels in response to the conversion from mycophenolate mofetil to mizoribine in kidney transplant recipients. eGFR, HGPRT, MMF, SUA
49  2013 Mizoribine as a safe and effective combined maintenance therapy with prednisolone for anti-neutrophil cytoplasmic antibody-associated vasculitis in a hemodialysis patient. CRP, HD, mPSL, PR3-ANCA, PSL
50  2013 Mizoribine selectively attenuates monocyte chemoattractant protein-1 production in cultured human glomerular mesangial cell: a possible benefit of its use in the treatment of lupus nephritis. MCP, MCs
51  2013 Mizoribine versus mycophenolate mofetil in combination therapy with tacrolimus for de novo kidney transplantation: evaluation of efficacy and safety. BPAR, MMF
52  2013 Randomized comparative trial of mizoribine versus mycophenolate mofetil in combination with tacrolimus for living donor renal transplantation. MMF
53  2013 Safety and efficacy of mizoribine in patients with connective tissue diseases other than rheumatoid arthritis. CTDs
54  2013 Study of the efficacy of mizoribine in lupus nephritis in Chinese patients. ---
55  2013 Synergistic protective effects of mizoribine and angiotensin II receptor blockade on cyclosporine A nephropathy in rats. ARB, CsA, TGF, VAL
56  2013 The argument for the use of mizoribine in renal transplantation: a meta-analysis and systemic review. AZA, CI, RR
57  2013 [Hyperuricemia and acute kidney injury following kidney transplantation : a case report]. ---
58  2012 An investigation of the correlation between blood concentration of mizoribine and its efficacy in treatment of rheumatoid arthritis based on indices of drug survival and improvement in DAS28-CRP. DAS28, MZR-C3, RA
59  2012 Chronopharmacology of mizoribine in collagen-induced arthritis rats. CIA, CRP, RA, TNF
60  2012 Efficacy and safety of multitarget therapy with mizoribine and tacrolimus for systemic lupus erythematosus with or without active nephritis. LN
61  2012 Excellent results with high-dose mizoribine combined with cyclosporine, corticosteroid, and basiliximab in renal transplant recipients: multicenter study in Japan. BAS, CMV
62  2012 Mizoribine requires individual dosing due to variation of bioavailability. ---
63  2012 Mizoribine suppresses proliferation of rat glomerular epithelial cells in culture and inhibits increase of monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 stimulated by thrombin. ELISA, GEC, MCP-1, MIP-2, RT-PCR
64  2012 The beneficial effect of high-dose mizoribine combined with cyclosporine, basiliximab, and corticosteroids on CMV infection in renal transplant recipients. CMV
65  2012 The efficacy and safety of high-dose mizoribine in ABO-incompatible kidney transplantation using anti-CD20 and anti-CD25 antibody without splenectomy treatment. ABOi, LKT, MMF
66  2011 Mizoribine provides effective treatment of sequential histological change of arteritis and reduction of inflammatory cytokines and chemokines in an animal model of Kawasaki disease. CAWS, IVIG, KD
67  2011 Mizoribine--an inosine monophosphate dehydrogenase inhibitor--acts synergistically with cyclosporine A in prolonging survival of murine islet cell and heart transplants across major histocompatibility barrier. CsA
68  2011 Novel multidrug therapy for children with cyclosporine-resistant or -intolerant nephrotic syndrome. FSGS, MCD, MMF, NS, PDN, SDNS, SRNS, Tac
69  2011 Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity. ADO, BthNK, Ino, NK, PfkB
70  2010 A novel target of mizoribine inhibiting mesangial cell proliferation: S phase kinase-associated protein 2. MC, Skp2
71  2010 Contrasting effects of steroids and mizoribine on macrophage activation and glomerular lesions in rat thy-1 mesangial proliferative glomerulonephritis. PSL
72  2010 Effects of probenecid on the pharmacokinetics of mizoribine and co-administration of the two drugs in patients with nephrotic syndrome. PK, PRB
73  2010 Efficacy and safety of mizoribine by one single dose administration for patients with rheumatoid arthritis. DMARD, EULAR, RA
74  2010 Efficacy and safety of single-dose mizoribine for patients with rheumatoid arthritis: results at 6 months after switching from a multiple-dose regimen without a change in total daily dose. RA
75  2010 Methylprednisolone pulse therapy combined with mizoribine following tonsillectomy for immunoglobulin A nephropathy: clinical remission rate, steroid sparing effect, and maintenance of renal function. CR, eGFR, IgAN
76  2010 Mizoribine attenuates renal injury and macrophage infiltration in patients with severe lupus nephritis. DPLN
77  2010 Mizoribine therapy in a patient with lupus nephritis: the association between mizoribine concentration and peritoneal dialysis. CAPD, SLE
78  2010 Single daily high-dose mizoribine therapy for children with steroid-dependent nephrotic syndrome prior to cyclosporine administration. SDNS
79  2010 Successful treatment of chronic lupus myocarditis with prednisolone and mizoribine. SLE
80  2010 The immunosuppressive drug mizoribine directly prevents podocyte injury in puromycin aminonucleoside nephrosis. GSK-3beta, ILK, PAN
81  2009 A case report of steroid-resistant antineutrophil cytoplasmic antibody-related vasculitis successfully treated by mizoribine in a hemodialysis patient. ANCA, MPO
82  2009 Effects of low-dose mizoribine pulse therapy in combination with methotrexate in rheumatoid arthritis patients with an insufficient response to methotrexate. DAS28, EULAR, MTX, RA
83  2009 Efficacy of mizoribine pulse therapy in patients with rheumatoid arthritis who show a reduced or insufficient response to infliximab. EULAR, HACA, MTX, RA
84  2009 Pharmacokinetic study of mizoribine in child-onset glomerulonephritis. ---
85  2009 Protective effects of Mizoribine on Cyclosporine A nephropathy in rats. CsA
86  2008 Mizoribine for renal sarcoidosis: effective steroid tapering and prevention of recurrence. PSL
87  2008 Mizoribine treatment of young patients with severe lupus nephritis: a clinicopathologic study by the tohoku pediatric study group. DPLN, ECLAM, MZR-P, PDN
88  2008 Oral mizoribine pulse therapy for steroid-dependent focal segmental glomerulosclerosis. ---
89  2007 A case of lupus nephritis improved after appropriately adjusting the dosage of mizoribine. mPSL, SLE
90  2007 Effects of mizoribine on MHC-restricted exogenous antigen presentation in dendritic cells. APCs, BMDCs, DCs, RA
91  2007 Long-term intermittent pulse therapy with mizoribine attenuates histologic progression in young patients with severe lupus nephritis: report of two patients. ---
92  2007 Mizoribine intermittent pulse protocol for induction therapy for systemic lupus erythematosus in children: an open-label pilot study with five newly diagnosed patients. ECLAM, PDN, SLE
93  2007 Mizoribine therapy for patients with lupus nephritis: the association between peak mizoribine concentration and clinical efficacy. Ccr, TP
94  2006 Acceptability and usefulness of mizoribine in the management of rheumatoid arthritis in methotrexate-refractory patients and elderly patients, based on analysis of data from a large-scale observational cohort study. IORRA, MTX
95  2006 Amelioration of steroids and cyclosporine-resistant nephrotic syndrome by pravastatin. FSGS, LDL
96  2006 Inhibitory effect of mizoribine on matrix metalloproteinase-1 production in synovial fibroblasts and THP-1 macrophages. LPS, MMP-1, SFs, THP-1 macrophages
97  2006 Long-term mizoribine intermittent pulse therapy for young patients with flare of lupus nephritis. SLE
98  2005 Effects of long-term treatment with mizoribine in patients with proliferative lupus nephritis. PSL
99  2005 High-dose mizoribine therapy for childhood-onset frequently relapsing steroid-dependent nephrotic syndrome with cyclosporin nephrotoxicity. CsA, CsAN, FR-SDNS
100  2005 Implication of the peak serum level of mizoribine for control of the serum anti-dsDNA antibody titer in patients with lupus nephritis. ---