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■ Abbreviation / Long Form : Mfn1 / mitofusin 1

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Total Number of Papers: 121
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Abbreviation:   Mfn1  (>> Co-occurring Abbreviation)
Long Form:   mitofusin 1
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2022 Alteration of Mitochondrial DNA Copy Number and Increased Expression Levels of Mitochondrial Dynamics-Related Genes in Sjögren's Syndrome. Mff, mtDNA, SS
2022 FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion. FUNDC2, HCC
2022 Glycine ameliorates MBP-induced meiotic abnormalities and apoptosis by regulating mitochondrial-endoplasmic reticulum interactions in porcine oocytes. DBP, ER, Gly, IVM, MAM, MBP, Mfn2, ROS, VDAC1
2022 Lycopene alleviates multiple-mycotoxin-induced toxicity by inhibiting mitochondrial damage and ferroptosis in the mouse jejunum. AFB1, DON, Fis1, FTH1, GPX4, LYC, MDA, ROS, SLC3A2, T-AOC, TfR1, ZEN, ZO-1
2022 miR-125b Disrupts Mitochondrial Dynamics via Targeting Mitofusin 1 in Cisplatin-Induced Acute Kidney Injury. AKI
2022 Mitochondrial dysfunction caused by targeted deletion of Mfn1 does not result in telomere shortening in oocytes. ---
2022 Mitoquinone mitigates paraquat-induced A549 lung epithelial cell injury by promoting MFN1/MFN2-mediated mitochondrial fusion. Mfn2, MitoQ, PQ, ROS
2022 Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway. ERalpha, Fis1, Mfn2, MYH3, MyoG, NRF1, PNF, TNF-alpha
2022 Protective effect of resveratrol on rat cardiomyocyte H9C2 cells injured by hypoxia/reoxygenation by regulating mitochondrial autophagy PTEN-induced putative kinase protein 1/Parkinson disease protein 2 signaling pathway. LC3B, Mfn2, PARL, ROS, TIM23
10  2022 Protective effects of silibinin against ethanol- or acetaldehyde-caused damage in liver cell lines involve the repression of mitochondrial fission. Drp1, OPA1, STS
11  2022 Puerarin Alleviates LPS-Induced H9C2 Cell Injury by Inducing Mitochondrial Autophagy. ADP, AMP, ATP, Drp1, LPS, ROS
12  2022 Targeted Deletion of Mitofusin 1 and Mitofusin 2 Causes Female Infertility and Loss of Follicular Reserve. Mfn2
13  2022 The Mfn1-βIIPKC Interaction Regulates Mitochondrial Dysfunction via Sirt3 Following Experimental Subarachnoid Hemorrhage. PKC, SAH, siRNA
14  2022 The Role of Mitochondrial Dynamic Dysfunction in Age-Associated Type 2 Diabetes. Drp1, Fis1, Mfn2, mtDNA, OPA1
15  2022 Uncovering the important role of mitochondrial dynamics in oogenesis: impact on fertility and metabolic disorder transmission. Drp1
16  2022 [Down-regulation of miR-29a inhibits mitochondrial fusion and fission in rat H9c2 cardiomyocytes induced by oxygen and glucose deprivation/reoxygenation]. Bax, Fis1, LDH, MDA, NC, OGD/R, OPA1, p-DRP1, p-ERK, SOD
17  2021 Allyl Methyl Sulfide Preserved Pressure Overload-Induced Heart Failure Via Modulation of Mitochondrial Function. alpha-SA, AMS, ANP, beta-MHC, Drp1, ETC, Mfn2, MnSOD, OCR, ROS, SD, TAC
18  2021 Alterations in Mitochondrial and Inflammasome Homeostasis by 2-Chloroethyl Ethyl Sulfide and Their Mitigation by Curcumin: An in Vitro Study. AIM2, CEES, Drp1, Fis1, Mfn2, NLRP3, SM
19  2021 Cardiac mitofusin-1 is reduced in non-responding patients with idiopathic dilated cardiomyopathy. c-Mfn1 KO, EM, IDCM, LV, NRVMs, TAC
20  2021 Does Metformin Modulate Mitochondrial Dynamics and Function in Type 2 Diabetic Patients? Drp1, Fis1, Mfn2, OPA1, T2D
21  2021 Exploring the effect of Gupi Xiaoji Prescription on hepatitis B virus-related liver cancer through network pharmacology and in vitro experiments. BATMAN-TCM, Fis1, GO, GXP, HBV, HCC, KEGG, Mfn2, OPA1, TCM, TCMID
22  2021 Gene expression profiles of mitochondria-endoplasmic reticulum tethering in human gingival fibroblasts in response to periodontal pathogens. F. nucleatum, GRP75, IER3, P. gingivalis, PINK1, SIGMAR1, TNF-alpha
23  2021 Mitochondrial Fusion Mediated by Mitofusin 1 Regulates Macrophage Mycobactericidal Activity by Enhancing Autophagy. HDT
24  2021 Nrf1 Knock-Down in the Hypothalamic Paraventricular Nucleus Alleviates Hypertension Through Intervention of Superoxide Production-Removal Balance and Mitochondrial Function. cyt c, GCLC, NE, NQO1, NRF1, PGC-1alpha, PRDX3, PVN
25  2021 Protective Effect of Manganese on Apoptosis and Mitochondrial Function of Heat-Stressed Primary Chick Embryonic Myocardial Cells. Drp1, Mn, MnSOD, OPA1
26  2021 Recombinant High-Mobility Group Box 1 (rHMGB1) Promotes NRF2-Independent Mitochondrial Fusion through CXCR4/PSMB5-Mediated Drp1 Degradation in Endothelial Cells. CXCR4, DAMP, Drp1, HMGB1, IL-1beta, Mfn2, NLRP3, NRF2, OPA1, PSMB5, RAGE, rHMGB1, rHMGB1, TEM, TLR2, TLR4
27  2021 Role of the lipid transport protein StarD7 in mitochondrial dynamics. CT, Drp1, ER, PC, ROS
28  2021 Tang Luo Ning, a Traditional Chinese Compound Prescription, Ameliorates Schwannopathy of Diabetic Peripheral Neuropathy Rats by Regulating Mitochondrial Dynamics In Vivo and In Vitro. DPN, Drp1, MBP, Mfn2, MMP, MPZ, OPA1, SRY, STZ, TLN
29  2021 To Research the Effects of Storage Time on Autotransfusion based on Erythrocyte Oxygen-Carrying Capacity and Oxidative Damage Characteristics. Mfn2, ROS
30  2020 Age-dependent impairment of adipose-derived stem cells isolated from horses. ASCs, CXCR4, ER, GLUT4, IL-8, INSR, IRE1, TNF-alpha, XBP1
31  2020 Deletion of Bmal1 Impairs Pancreatic beta-Cell Function via Mitochondrial Signaling Pathway. BMAL1, Fis1, Mfn2, siRNA
32  2020 Denervation drives skeletal muscle atrophy and induces mitochondrial dysfunction, mitophagy and apoptosis via miR-142a-5p/MFN1 axis. TA, TEM
33  2020 Effect of ApoE isoforms on mitochondria in Alzheimer disease. AD, DLP1, FoxO3A, Mfn2, PGC-1alpha, PSD-95, SIRT3, SOD2, SYN1
34  2020 Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission. AAA, Ang II, eIF5A, KLF5, ROS, VSMC
35  2020 Knocking-out the Siah2 E3 ubiquitin ligase prevents mitochondrial NCX3 degradation, regulates mitochondrial fission and fusion, and restores mitochondrial function in hypoxic neurons. AR, Drp1, FF, NCX3, OGD, OMM, SIAH2
36  2020 Lentinan-functionalized Selenium Nanoparticles target Tumor Cell Mitochondria via TLR4/TRAF3/MFN1 pathway. Cav-1, LNT, TLR4, TRAF3
37  2020 miR-20b suppresses mitochondrial dysfunction-mediated apoptosis to alleviate hyperoxia-induced acute lung injury by directly targeting MFN1 and MFN2. ACE IIs, HALI, ROS
38  2020 Mitofusin1 Is a Major Mediator in Glucose-Induced Epithelial-to-Mesenchymal Transition in Lung Adenocarcinoma Cells. EMT, LAD, Pink
39  2020 Mitofusin1 is required for oocyte growth and communication with follicular somatic cells. ---
40  2020 Neuregulin-1 promotes mitochondrial biogenesis, attenuates mitochondrial dysfunction, and prevents hypoxia/reoxygenation injury in neonatal cardiomyocytes. Mfn2, NRCMs, NRG-1, NRG1, PGC-1alpha, rhNRG-1
41  2020 NFATc3-dependent expression of miR-153-3p promotes mitochondrial fragmentation in cardiac hypertrophy by impairing mitofusin-1 expression. ISO
42  2020 Regulation of mitochondrial dynamics and energetics in the diabetic renal proximal tubule by the beta2-adrenergic receptor agonist formoterol. Drp1, ETC, RPTCs
43  2020 Silibinin treatment results in reducing OPA1&MFN1 genes expression in a rat model hepatic ischemia-reperfusion. i.p, IR, OPA1
44  2020 The Crosstalk between Cardiac Lipotoxicity and Mitochondrial Oxidative Stress in the Cardiac Alterations in Diet-Induced Obesity in Rats. cycloF, PA
45  2020 The GDP-Bound State of Mitochondrial Mfn1 Induces Membrane Adhesion of Apposing Lipid Vesicles through a Cooperative Binding Mechanism. GUVs, Mfn2
46  2020 Therapeutic potential of targeting mitochondrial dynamics in cancer. Drp1, Mfn2, OPA1
47  2019 A selective inhibitor of mitofusin 1-betaIIPKC association improves heart failure outcome in rats. betaIIPKC
48  2019 Ablation of TMEM126B protects against heart injury via improving mitochondrial function in high fat diet (HFD)-induced mice. Drp1, Fis1, HFD, PA, ROS, TMEM126B, WT
49  2019 Cardioprotective Regimen of Adaptation to Chronic Hypoxia Diversely Alters Myocardial Gene Expression in SHR and SHR-mtBN Conplastic Rat Strains. Acer2, Aco1, Casp3, CAT, CNH, DRP, HK2, Hmox2, Pkce, Pla2g5, Ppla2g2a, Sgms2, SHR
50  2019 Danqi Tablet () Regulates Energy Metabolism in Ischemic Heart Rat Model through AMPK/SIRT1-PGC-1alpha Pathway. AMPK, ATP, Mfn2, PGC-1alpha, SIRT1, SOD2, TMZ
51  2019 Dysregulated Mitochondrial Dynamics and Metabolism in Obesity, Diabetes, and Cancer. Drp1, OPA1, TCA
52  2019 Effects of Al Exposure on Mitochondrial Dynamics in Rat Hippocampus. Al, CaN, Drp1, Fis1, Mfn2, OPA1
53  2019 Expression of mitochondrial dynamics markers during melanoma progression: Comparative study of head and neck cutaneous and mucosal melanomas. AMT, Drp1, Fis1, Mfn2, MMs
54  2019 Gemini-Based Lipoplexes Complement the Mitochondrial Phenotype in MFN1-Knockout Mouse Embryonic Fibroblasts. GCLs, MDs, MFN1-KO MEFs, Mfn2
55  2019 Identification and characterization of signal peptide of Mitofusin1 (Mfn1). OMM
56  2019 IDH2 protects against nonalcoholic steatohepatitis by alleviating dyslipidemia regulated by oxidative stress. Drp1, Fis1, HFD, IDH2, KO, NAFLD
57  2019 Inhibiting neddylation modification alters mitochondrial morphology and reprograms energy metabolism in cancer cells. ---
58  2019 Interval and continuous exercise overcome memory deficits related to beta-Amyloid accumulation through modulating mitochondrial dynamics. CAT, Drp1, Fis1, HIIT, MDA, Mfn2, MICT, OPA1, ROS, SOD
59  2019 Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice. ---
60  2019 Nrf2 deficiency exacerbates frailty and sarcopenia by impairing skeletal muscle mitochondrial biogenesis and dynamics in an age-dependent manner. CSA, Drp1, Mfn2, mtDNA, NRF1, Nrf2, OPA1, PGC-1alpha, WT
61  2019 Phenotypic selection with an intrabody library reveals an anti-apoptotic function of PKM2 requiring Mitofusin-1. IB5, MOMP, PKM2, scFvs
62  2019 Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells. Drp1, DS, OPA1, PGZ, ROS
63  2019 Protective effects of vitamin E on cadmium-induced apoptosis in rat testes. Cd, Mfn2
64  2019 TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function. BAD, HIV, ssRNA, TLR8
65  2019 [The role of abnormal mitochondrial fusion and fission in PBDE-47-induced change in mitochondrial mass in PC12 cells]. Fis1, NAO
66  2018 Activation of protein kinase C-alpha/heme oxygenase-1 signaling pathway improves mitochondrial dynamics in lipopolysaccharide-activated NR8383 cells. Drp1, Fis1, HO-1, LPS, Mfn2, OPA1, PKCalpha, RCR, ROS
67  2018 Benfotiamine, a Lipid-Soluble Analog of Vitamin B1, Improves the Mitochondrial Biogenesis and Function in Blunt Snout Bream (Megalobrama amblycephala) Fed High-Carbohydrate Diets by Promoting the AMPK/PGC-1beta/NRF-1 Axis. AMP, AMPK, ATP, ATP-6, COX-2, cytb, Drp1, FCR, Fis1, HC, Mff, NRF1, OPA1, PGC-1beta, RFI, SGR, WGR
68  2018 Chronic Exercise Improves Mitochondrial Function and Insulin Sensitivity in Brown Adipose Tissue. BAT, CPT II, Drp1, ET, IGF-1R, IR, L-OPA1, NRF1, p-IRS-1, PGC1alpha, S-OPA1, SIRT1, UCP
69  2018 Deficiency of Sphingosine-1-Phosphate Reduces the Expression of Prohibitin and Causes beta-Cell Impairment via Mitochondrial Dysregulation. GSIS, MIN6, PHB, S1P, SphK, SphKi
70  2018 Mitochondrial dynamics as an underlying mechanism involved in aerobic exercise training-induced cardioprotection against ischemia-reperfusion injury. Drp1, Mfn2
71  2018 Nagarse treatment of cardiac subsarcolemmal and interfibrillar mitochondria leads to artefacts in mitochondrial protein quantification. Cx43, SSM
72  2018 Tributyltin Inhibits Neural Induction of Human Induced Pluripotent Stem Cells. iPSCs, TBT
73  2018 [Effects of fluoride exposure on thyroid hormone level and intelligence in rats]. Fis1
74  2017 Advanced glycation end products influence mitochondrial fusion-fission dynamics through RAGE in human aortic endothelial cells. AGE-BSA, AGEs, Drp1, Mfn2, OPA1, PINK1, PTEN, RAGE
75  2017 Effect of Mahuang Gancao Ganjiang Decoction on Fusion and Fission of Mitochondria and Apoptosis of Lymphocytes in Mice under Cold Stress. Drp1, Fis1, Mfn2, MGGD, Opa-1
76  2017 Effects of trimetazidine on mitochondrial respiratory function, biosynthesis, and fission/fusion in rats with acute myocardial ischemia. Drp1, OPA1, PPARgamma
77  2017 MiR-125a regulates mitochondrial homeostasis through targeting mitofusin 1 to control hypoxic pulmonary vascular remodeling. PASMCs
78  2017 Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications. Drp1, Fis1, mdivi-1, Mff, Mfn2, PINK1, ROS
79  2017 Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control. POMC
80  2017 Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity. ---
81  2017 Mitofusin 1 and optic atrophy 1 shift metabolism to mitochondrial respiration during aging. BHI, NHFs, OCR, OPA1
82  2017 Pro-Inflammatory CXCR3 Impairs Mitochondrial Function in Experimental Non-Alcoholic Steatohepatitis. Drp1, Fis1, NASH, ROS, TEM, WT
83  2017 Renal cold storage followed by transplantation impairs expression of key mitochondrial fission and fusion proteins. CS, Mff, Mfn2
84  2017 The ARL2 GTPase regulates mitochondrial fusion from the intermembrane space. IMS, Mfn2, SIM
85  2016 Curcumin prevents mitochondrial dynamics disturbances in early 5/6 nephrectomy: Relation to oxidative stress and mitochondrial bioenergetics. CKD, NOS, NOX
86  2016 Exercise mitigates mitochondrial permeability transition pore and quality control mechanisms alterations in nonalcoholic steatohepatitis. ET, Mfn2, mPTP, NASH, VPA
87  2016 MicroRNA-140 is elevated and mitofusin-1 is downregulated in the right ventricle of the Sugen5416/hypoxia/normoxia model of pulmonary arterial hypertension. miRs, PAH, RV
88  2016 Mitochondrial Dynamics and Mitochondrial Dysfunction in Diabetes. Drp1, ERRs, Fis1, Mff, Mfn2, NRFs, OPA1, PGC-1alpha, PINK1, PPARs, PTEN, ROS
89  2016 Mitochondrial Fission Increases Apoptosis and Decreases Autophagy in Renal Proximal Tubular Epithelial Cells Treated with High Glucose. LC3, TUNEL
90  2016 Mitochondrial fusion: Reaching the end of mitofusin's tether. ---
91  2016 Regulation of Mitofusin1 by Mahogunin Ring Finger-1 and the proteasome modulates mitochondrial fusion. MGRN1
92  2015 Acetyl-L-carnitineameliorates mitochondrial damage and apoptosis following spinal cord injury in rats. ALC, Bax, Drp1, Fis1, SCI
93  2015 Analysis of mitochondrial structure and function in the Drosophila larval musculature. IFM, OPA1, PD
94  2015 Leptin-induced mitochondrial fusion mediates hepatic lipid accumulation. FRD, PGC
95  2015 Mitofusin 2 expression dominates over mitofusin 1 exclusively in mouse dorsal root ganglia - a possible explanation for peripheral nervous system involvement in Charcot-Marie-Tooth 2A. CMT2A, DRGs, Mfn2
96  2015 The cap-translation inhibitor 4EGI-1 induces mitochondrial dysfunction via regulation of mitochondrial dynamic proteins in human glioma U251 cells. Drp1, MMP, NAC, OPA1, ROS
97  2015 The effects of calcipotriol on the dendritic morphology of human melanocytes under oxidative stress and a possible mechanism: is it a mitochondrial protector? Drp1, LC3, MDA, Mfn2, MMP, ROS, SOD
98  2014 Bitter gourd inhibits the development of obesity-associated fatty liver in C57BL/6 mice fed a high-fat diet. BG, Drp1, HFD
99  2014 Expression patterns of mitochondrial OXPHOS components, mitofusin 1 and dynamin-related protein 1 are associated with human embryo fragmentation. Drp1, HF, LF, MMP, mtDNA, OXPHOS
100  2014 MFN1 deacetylation activates adaptive mitochondrial fusion and protects metabolically challenged mitochondria. ---