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■ Abbreviation / Long Form : NF-kappaB / nuclear transcription factor-kappaB

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Total Number of Papers: 533
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Abbreviation:   NF-kappaB  (>> Co-occurring Abbreviation)
Long Form:   nuclear transcription factor-kappaB
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No. Year Title Co-occurring Abbreviation
2021 A New Peracetylated Oleuropein Derivative Ameliorates Joint Inflammation and Destruction in a Murine Collagen-Induced Arthritis Model via Activation of the Nrf-2/Ho-1 Antioxidant Pathway and Suppression of MAPKs and NF-κB Activation. CIA, COMP, HO-1, MAPK, Nrf2, OL, SLE
2021 A novel gastroprotective effect of zeaxanthin against stress-induced gastritis in male rats targeting the expression of HIF-1α, TFF-1 and MMP-9 through PI3K/Akt/JNK signaling pathway. HIF-1alpha, IL-1beta, MDA, MMP-9, MPO, PGE2, TFF1, TOS, WAS, ZE
2021 A Systematic Study of Mechanism of Sargentodoxa cuneata and Patrinia scabiosifolia Against Pelvic Inflammatory Disease With Dampness-Heat Stasis Syndrome via Network Pharmacology Approach. CBA, FA, IL-6, PPI, PS, TLR, TNF, VEGFA, vWF
2021 A tandem activation of NLRP3 inflammasome induced by copper oxide nanoparticles and dissolved copper ion in J774A.1 macrophage. IL, MyD88, NLRP3, TLR4
2021 Aerobic exercise ameliorates particulate matter-induced lung injury in aging rats. iHSP70, IKKbeta, PM2.5, TLR4
2021 Betulinic acid attenuates cyclophosphamide-induced intestinal mucosa injury by inhibiting the NF-κB/MAPK signalling pathways and activating the Nrf2 signalling pathway. BA, CYP, MAPK, NF-E2, ROS
2021 Bone marrow mesenchymal stem cells-derived exosomes reduce apoptosis and inflammatory response during spinal cord injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway. BMSCs, LPS, MyD88, SCI, TLR4, TNF
2021 Downregulated fat mass and obesity-associated protein inhibits bone resorption and osteoclastogenesis by nuclear factor-kappa B inactivation. BMMs, FTO, NFATc1, TRAP
2021 Effect of melittin on iNOS and NF-κB expression induced by IL-1βin C518 cells. IL-1beta, iNOS, MEL
10  2021 Effects of Enalapril on TLR2/NF-κB Signaling Pathway and Inflammatory Factors in Rabbits with Chronic Heart Failure. ACEI, CHF, TLR2
11  2021 Fab Fragment of Immunoglobulin Y Modulates NF-κB and MAPK Signaling through TLR4 and αVβ3 Integrin and Inhibits the Inflammatory Effect on R264.7 Macrophages. COX-2, IgY, IL-10, IL-6, iNOS, LPS, MAPK, NO, PGE2, TNF-alpha
12  2021 FBXW11 deletion alleviates Alzheimer's disease by reducing neuroinflammation and amyloid-β plaque formation via repression of ASK1 signaling. AD, ASK1, Fbxw11, MAPK
13  2021 Lipopolysaccharide stimulates bovine endometrium explants through toll‑like receptor 4 signaling and PGE2 synthesis. 15-PGDH, DAMP, LPS, PGE2, PKA
14  2021 Novel Seleno-Aspirinyl Compound AS-10 Induces Apoptosis, G1 Arrest of Pancreatic Ductal Adenocarcinoma Cells, Inhibits Their NF-κB Signaling, and Synergizes with Gemcitabine Cytotoxicity. IkappaB, PDAC, TNF-alpha
15  2021 Omega-3 polyunsaturated fatty acids ameliorated inflammatory response of mammary epithelial cells and mammary gland induced by lipopolysaccharide. IL, LPS
16  2021 Pain Relief Dependent on IL-17-CD4+ T Cell-β-Endorphin Axis in Rat Model of Brachial Plexus Root Avulsion After Electroacupuncture Therapy. BPRA, DCs, EA, IFN-gamma, MDSCs, NK
17  2021 Resveratrol prevents steroid-induced osteonecrosis of the femoral head via miR-146a modulation. FOXO, miR-146a, RANKL, RES, Runt2, Sirt1
18  2021 RNF31 mediated ubiquitination of A20 aggravates inflammation and hepatocyte apoptosis through the TLR4/MyD88/NF-κB signaling pathway. LPS, MyD88, RNF31, TLR4
19  2021 Sterenin M as a potential inhibitor of SARS-CoV-2 main protease identified from MeFSAT database using molecular docking, molecular dynamics simulation and binding free energy calculation. COVID-19, MD, Mpro
20  2021 The cardioprotective effect of astaxanthin against isoprenaline-induced myocardial injury in rats: involvement of TLR4/NF-κB signaling pathway. CVDs, TLR4, TNF-alpha
21  2021 USP13 mediates PTEN to ameliorate osteoarthritis by restraining oxidative stress, apoptosis and inflammation via AKT-dependent manner. CIA, DUB, HFLSs, IL-1beta, LPS, Nrf2, PTEN, TNF-alpha, USP13
22  2021 [Anti-asthmatic effect of agarwood alcohol extract in mice and its mechanism]. Agar-Wit, ELISA, HMGB1, IL-1beta, OVA, RT-PCR, TNFR, WBC
23  2021 [Protective effects of total saponins of Codonopsis on ulcerative colitis induced by TNBS in rats and its mechanism]. CMDI, DAI, IL-10, IL-6, MDA, SOD, TNBS, TSC
24  2020 Acute Increase in O-GlcNAc Improves Survival in Mice With LPS-Induced Systemic Inflammatory Response Syndrome. CLP, IL-1beta, IL-6, O-GlcNAcylation, SIRS
25  2020 An engineering probiotic producing defensin-5 ameliorating dextran sodium sulfate-induced mice colitis via Inhibiting NF-kB pathway. DSS, HD5, L. lactis, TJ
26  2020 Anti-Inflammatory Effect of Simonsinol on Lipopolysaccharide Stimulated RAW264.7 Cells through Inactivation of NF-κB Signaling Pathway. ELISA, IL-6, iNOS, LPS, NO, RT-PCR, TNF-alpha
27  2020 Astragaloside IV ameliorates intermittent hypoxia-induced inflammatory dysfunction by suppressing MAPK/NF-kappaB signalling pathways in Beas-2B cells. AS-IV, IL, LDH, MAPK, MDA, OSA, ROS, SOD, TLR4
28  2020 Characterization of lamprey (Lampetra japonica) tnfr10-like gene: A potential granulocyte marker molecule and its immune functions. TNF, TNFRSF
29  2020 Chondroprotective Properties of Human-Enriched Serum Following Polyphenol Extract Absorption: Results from an Exploratory Clinical Trial. HT, IL-1beta, PCy
30  2020 Coixol Suppresses NF-kappaB, MAPK Pathways and NLRP3 Inflammasome Activation in Lipopolysaccharide-Induced RAW 264.7 Cells. COX, IL, iNOS, LPS, MAPKs, NLRP, NO, TNF
31  2020 CSB6B prevents β-amyloid-associated neuroinflammation and cognitive impairments via inhibiting NF-κB and NLRP3 in microglia cells. AD, CSB6B, NLRP3
32  2020 DNMT3b-mediated methylation of ZSWIM3 enhances inflammation in alcohol-induced liver injury via regulating TRAF2-mediated NF-κB pathway. 5'-UTR, ALD, ALI, ChIP, DNMTs, EtOH, TRAF2
33  2020 Echinacoside attenuates inflammatory response in a rat model of cervical spondylotic myelopathy via inhibition of excessive mitochondrial fission. CSM, ECH, NLRP3, ROS
34  2020 Effect of GNAQ alteration on RANKL-induced osteoclastogenesis in human non-small-cell lung cancer. GNAQ, IkappaB, M-CSF, RANKL, TNF-alpha
35  2020 High Expression of Nuclear Transcription Factor-kappaB is Associated with Cisplatin Resistance and Prognosis for Ovarian Cancer. CR, LN
36  2020 High-intensity interval training is more effective than continuous training to reduce inflammation markers in female rats with cisplatin nephrotoxicity. CP, HIIT, IL-1beta, IL-6, MCP-1, TLR4, TNF-alpha
37  2020 Human-origin Lactobacillus salivarius AR809 protects against immunosuppression in S. aureus-induced pharyngitis via Akt-mediated NF-kappaB and autophagy signaling pathways. Akt, COX-2, IL-1beta, iNOS, LC3-II, NO, PGE2, ROS, S. aureus, TNF-alpha
38  2020 Jianpi Huazhuo Tiaozhi granules reduce oxidative stress injury in macrophages by inhibiting the nicotinamide adenine dinucleotide phosphate oxidase/reactive oxygen species-nuclear transcription factor kappa B pathway. IKK-alpha, IKK-beta, JHTG, NOX, ROS
39  2020 Kidney Ischemia-Reperfusion Elicits Acute Liver Injury and Inflammatory Response. AKI, IR, MPO
40  2020 Longxuetongluo capsule alleviates lipopolysaccharide-induced neuroinflammation by regulating multiple signaling pathways in BV2 microglia cells. CM, COX-2, ELISA, EMSA, ERK, iNOS, JAK/STAT, LDH, LPS, LTC, MAPKs, MTS, NO, OGD/R, PGE2, TNF-alpha
41  2020 Luteolin alleviates neuroinflammation via downregulating the TLR4/TRAF6/NF-κB pathway after intracerebral hemorrhage. ICH, oxyHb, SBI, TLR4, TRAF6
42  2020 Mammary Transcriptome Profile during Peak and Late Lactation Reveals Differentially Expression Genes Related to Inflammation and Immunity in Chinese Holstein. DEGs, SCC
43  2020 miR-205/IRAK2 signaling pathway is associated with urban airborne PM2.5-induced myocardial toxicity. IRAK2, MDA, miR-205, ROS, TRAF6
44  2020 MiR-7a ameliorates spinal cord injury by inhibiting neuronal apoptosis and oxidative stress. BBB, miR-7a, SCI
45  2020 MTMR14 protects against hepatic ischemia-reperfusion injury through interacting with AKT signaling in vivo and in vitro. AST, HR, IR, Tg
46  2020 Neuropeptide Y nerve paracrine regulation of prostate cancer oncogenesis and therapy resistance. NPY, PCa, RT
47  2020 Novel complementary coloprotective effects of metformin and MCC950 by modulating HSP90/NLRP3 interaction and inducing autophagy in rats. AMPK, DAI, DSS, IL-6, MDI, MPO, TLR4, TNF-alpha, UC
48  2020 Overexpression of COX7RP promotes tumor growth and metastasis by inducing ROS production in hepatocellular carcinoma cells. EMT, HCC, ROS
49  2020 PGAM1 deficiency ameliorates myocardial infarction remodeling by targeting TGF-β via the suppression of inflammation, apoptosis and fibrosis. JNK, MI-R, OGDR, PGAM1, TGF-beta
50  2020 Polysulfide and Hydrogen Sulfide Ameliorate Cisplatin-Induced Nephrotoxicity and Renal Inflammation through Persulfidating STAT3 and IKKβ. BUN, COX-2, IKKbeta, IL-1beta, IL-6, STAT3, TNF-alpha
51  2020 Protective effects of chondroitin sulphate nano-selenium on a mouse model of Alzheimer's disease. AD, GSH-Px, GSK-3beta, MDA, p38 MAPK, SOD
52  2020 STK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8+ T-Cells. GSEA, STK3
53  2020 The effects of inhibiting the activation of hepatic stellate cells by lignan components from the fruits of Schisandra chinensis and the mechanism of schisanhenol. ERK, HSCs, JNK, MAPK, TGF-beta
54  2020 The Maternal Diet with Fish Oil Might Decrease the Oxidative Stress and Inflammatory Response in Sows, but Increase the Susceptibility to Inflammatory Stimulation in their Offspring. AKP, FD, GSH-Px, HDL-C, IgG, IL-10, IL-1beta, IL-6, LPS, SD, T-AOC, TNF-alpha
55  2020 The possible protective effect of Nano-Selenium on the endocrine and exocrine pancreatic functions in a rat model of acute pancreatitis. AP, Bcl-2, HOMA-beta, IL-1beta
56  2020 The role of perilipin 2 in Pseudomonas aeruginosa pulmonary infection. COX-2, cPLA2, LD, PBS, PLIN2
57  2020 [Effect of electroacupuncture preconditioning on the expressions of NF-κB p65, IκBα and IKKβ in myocardial tissue of the rats with acute myocardial ischemia-reperfusion injury]. EA, ECG, IkappaB, IKK, MIRI
58  2019 A New Use for an Old Drug: Carmofur Attenuates Lipopolysaccharide (LPS)-Induced Acute Lung Injury via Inhibition of FAAH and NAAA Activities. ALI, CB2, FAAH, LPS, NAAA, PPARalpha
59  2019 A Novel Quinolyl-Substituted Analogue of Resveratrol Inhibits LPS-Induced Inflammatory Responses in Microglial Cells by Blocking the NF-kappaB/MAPK Signaling Pathways. IL-6, iNOS, LPS, MAPK, NADPH, NO, ROS, TLR4, TNF-alpha
60  2019 A review on fish immuno-nutritional response to indispensable amino acids in relation to TOR, NF-kappaB and Nrf2 signaling pathways: Trends and prospects. IAAs, Nrf2, TOR
61  2019 Acid microenvironment promotes cell survival of human bone sarcoma through the activation of cIAP proteins and NF-kappaB pathway. V-ATPase
62  2019 Adenosine A2A Receptor Mediates Inhibition of Synovitis and Osteoclastogenesis after Electroacupuncture in Rats with Collagen-Induced Arthritis. A2AR, CIA, EA, PKA, RANKL, TNF-alpha, TRAP
63  2019 Anti-Allergic and Anti-Inflammatory Effects of Kuwanon G and Morusin on MC/9 Mast Cells and HaCaT Keratinocytes. 5-LO, AD, ELISA, IFN-gamma, STAT1, TNF-alpha
64  2019 Anti-inflammatory Activity of Ursolic Acid in MPTP-Induced Parkinsonian Mouse Model. Iba1, MPTP, PD, SNpc, TH, TNF-alpha, UA
65  2019 Butylphthalide ameliorates airway inflammation and mucus hypersecretion via NF-kappaB in a murine asthma model. BALF, ELISA, Muc5ac, OVA, RT-PCR, tIgE, TNF-alpha
66  2019 Citrus Alkaline Extract Delayed the Progression of Pulmonary Fibrosis by Inhibiting p38/NF-kappaB Signaling Pathway-Induced Cell Apoptosis. BALF, CAE, Hyp, IL-17, PGE2
67  2019 Danggui buxue tang inhibited mesangial cell proliferation and extracellular matrix accumulation through GAS5/NF-kappaB pathway. Col IV, DGT, DN, FN, GAS5, HG, IKK, LN, lncRNA
68  2019 Dexmedetomidine ameliorates memory impairment in sleep-deprived mice. BDNF, GFAP, IkappaBalpha, IL, TNF-alpha, TrkB
69  2019 Dietary oleuropein and its new acyl-derivate attenuate murine lupus nephritis through HO-1/Nrf2 activation and suppressing JAK/STAT, NF-kappaB, MAPK and NLRP3 inflammasome signaling pathways. JAK/STAT, MAPKs, NLRP3, Nrf2, OL, Per-OL, SLE
70  2019 Essential element Cu and non-essential element Hg exposures have different toxicological effects in the liver of large yellow croaker. MTs, Nrf2, ROS
71  2019 Florfenicol alleviated lipopolysaccharide (LPS)-induced inflammatory responses in Ctenopharyngodon idella through inhibiting toll / NF-kappaB signaling pathways. COX-2, FFC, HK, LPS, MyD88, NO, PGE 2, TAK1, TLR2, TRAF6
72  2019 Ginsenoside Rg1 Exerts Anti-inflammatory Effects via G Protein-Coupled Estrogen Receptor in Lipopolysaccharide-Induced Microglia Activation. COX-2, GPER, IL-1beta, iNOS, LPS, siRNA, TNF-alpha
73  2019 Hypothermia treatment ameliorated cyclin-dependent kinase 5-mediated inflammation in ischemic stroke and improved outcomes in ischemic stroke patients. Cdk5, IL-1beta, SD
74  2019 Immunoregulatory and anti-inflammatory properties of Crocus sativus (Saffron) and its main active constituents: A review. COX-2, IFN-gamma, IL, iNOS, MPO, PPARgamma, TNF-alpha
75  2019 Loss of Annexin A5 expression attenuates the lipopolysaccharide-induced inflammatory response of rat alveolar macrophages. ALI, AMs, AnxA5, IkappaB, LPS, mRNAs, Nrf2, qRT-PCR, TNF-alpha
76  2019 Pleiotropic Pharmacological Actions of Capsazepine, a Synthetic Analogue of Capsaicin, against Various Cancers and Inflammatory Diseases. CHOP, JAK, LPS, ROS, STAT, TRPA1, TRPV1
77  2019 Progranulin attenuates liver fibrosis by downregulating the inflammatory response. MCD, NASH, PGRN, TNF
78  2019 Propofol Pretreatment Prevents Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-induced Inflammation Through Nuclear Transcription Factor κB (NF-κB) Pathway in Neuroblastoma Cells. IL-1beta, OGD/R, TNF-alpha
79  2019 RAGE/NF-kappaB pathway mediates hypoxia-induced insulin resistance in 3T3-L1 adipocytes. IR, IRS-1, OSA, RAGE
80  2019 Rotula aquatica Lour. mitigates oxidative stress and inflammation in acute pyelonephritic rats. IL-6, MDA, ROS, THP, TLR4, TNF-alpha
81  2019 Shenfu Injection Attenuates Bile Duct Injury in Rats with Acute Obstructive Cholangitis. ALT, AOC, BDL, LPS, SFI, TB, TNF-alpha
82  2019 Silencing of nuclear factor kappa b 1 gene expression inhibits colony formation, cell migration and invasion via the downregulation of interleukin 1 beta and matrix metallopeptidase 9 in renal cell carcinoma. IL-1beta, RCC, RT-qPCR
83  2019 SIRT6 abrogation promotes adrenocortical carcinoma through activation of NF-kappaB signaling. ACC, SIRT6
84  2019 Toxicological effects of waterborne Zn on the proximal and distal intestines of large yellow croaker Larimichthys crocea. LPO, Nrf2, PC, ROS
85  2019 Z-ajoene from Crushed Garlic Alleviates Cancer-Induced Skeletal Muscle Atrophy. FOXO, MAPK
86  2018 Andrographolide ameliorates intracerebral hemorrhage induced secondary brain injury by inhibiting neuroinflammation induction. ICH, NLRP3, SBI
87  2018 Anti-inflammatory action of ambuic acid, a natural product isolated from the solid culture of Pestalotiopsis neglecta, through blocking ERK/JNK mitogen-activated protein kinase signaling pathway. COX-2, IL-6, iNOS, JNK, LPS, MAPK, NO, PGE2, TNF-alpha
88  2018 Anti-Inflammatory Effects of Gingerol on Lipopolysaccharide-Stimulated RAW 264.7 Cells by Inhibiting NF-kappaB Signaling Pathway. COX-2, IL, iNOS, LPS, NO, PGE2, TNF-alpha
89  2018 Astaxanthin protects lipopolysaccharide-induced inflammatory response in Channa argus through inhibiting NF-kappaB and MAPKs signaling pathways. ERK, IkappaBalpha, JNK, LDH, LPS, MAPK, MDA, NO, TLR4
90  2018 Biotin and chromium histidinate improve glucose metabolism and proteins expression levels of IRS-1, PPAR-gamma, and NF-kappaB in exercise-trained rats. AST, CrHis, HDL, IRS-1, PPARgamma, TC, TG
91  2018 Casein glycomacropeptide hydrolysates inhibit PGE2 production and COX2 expression in LPS-stimulated RAW 264.7 macrophage cells via Akt mediated NF-kappaB and MAPK pathways. COX-2, cPLA2, ERK, GMPH, LPS, MDA, PEG2, ROS
92  2018 DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis. ADC, AP-1, CXCL8, DACH1, ELISA, NSCLC
93  2018 Docoxahexaenoic Acid Induces Apoptosis of Pancreatic Cancer Cells by Suppressing Activation of STAT3 and NF-kappaB. DHA, EGFR, STAT3
94  2018 Effects of dietary lysine restriction on inflammatory responses in piglets. IL-8
95  2018 Fisetin inhibits the generation of inflammatory mediators in interleukin-1beta-induced human lung epithelial cells by suppressing the NF-kappaB and ERK1/2 pathways. ICAM-1, IL-1beta
96  2018 Implantation of adipose-derived stem cells cures the optic nerve injury on rats through inhibiting the expression of inflammation factors in the TLR4 signaling pathway. ADSCs, ELISA, FVEP, IL, Mac-1, MyD88, SD, TLR4, TNF
97  2018 Inhibiting RIPK1 Limits Neuroinflammation and Alleviates Postoperative Cognitive Impairments in D-Galactose-Induced Aged Mice. D-gal, Nec-1, PI, POCD, RIPK1
98  2018 Lobeglitazone Attenuates Airway Inflammation and Mucus Hypersecretion in a Murine Model of Ovalbumin-Induced Asthma. AHR, AP, Ig, LB, MUC5AC, OVA, PPAR
99  2018 Magnoliae Cortex and maize modulate Porphyromonas gingivalis-induced inflammatory reactions. ELISA, IL, iNOS, MAPK, MTT, PGE2
100  2018 miR-15b reduces amyloid-β accumulation in SH-SY5Y cell line through targetting NF-κB signaling and BACE1. AD, APP, IkappaB, qPCR