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■ Abbreviation / Long Form : NRF1 / nuclear respiratory factor 1

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Total Number of Papers: 430
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Abbreviation:   NRF1  (>> Co-occurring Abbreviation)
Long Form:   nuclear respiratory factor 1
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No. Year Title Co-occurring Abbreviation
2022 2,2',4,4'-Tetrabromodiphenyl ether disrupts spermatogenesis in mice by interfering with the ER-Nrf1-Tfam-mitochondria pathway. ER, ICR, RNAi
2022 Activation of AMPK-PGC-1α pathway ameliorates peritoneal dialysis related peritoneal fibrosis in mice by enhancing mitochondrial biogenesis. AMPK, mtDNA, PD, PF, PMCs, TUNEL
2022 Activation of PPARγ Protects Obese Mice from Acute Lung Injury by Inhibiting Endoplasmic Reticulum Stress and Promoting Mitochondrial Biogenesis. ALI, APN, ARDS, CHOP, ER, Mfn2, PPARgamma, RSG
2022 Brain infiltration of breast cancer stem cells is facilitated by paracrine signaling by inhibitor of differentiation 3 to nuclear respiratory factor 1. BBB, BCSCs, eSCs, ID3
2022 Caveolin-1 accelerates hypoxia-induced endothelial dysfunction in high-altitude cerebral edema. BBB, Cav-1, HACE, HH, TEER
2022 DEHP-induced mitophagy and mitochondrial damage in the heart are associated with dysregulated mitochondrial biogenesis. DEHP, Nrf2
2022 Differential Susceptibility of Retinal Neurons to the Loss of Mitochondrial Biogenesis Factor Nrf1. ---
2022 Dihydromyricetin alters myosin heavy chain expression via AMPK signaling pathway in porcine myotubes. AMPK, DHM, MyHC, p-CaMKKbeta, PGC-1alpha, Sirt1
2022 Effects of Age and Lifelong Moderate-Intensity Exercise Training on Rats' Testicular Function. OXPHOS
10  2022 Effects of Aspalathin on Insulin Resistance and Mitochondrial Dysfunction in Cultured Skeletal Muscle Cells - Potential Implications for Type 2 Diabetes Mellitus Therapy. CPT1, FATP1, IL-6, IR, PKCtheta, SIRT1, T2DM, TFAM, TNF-alpha
11  2022 Effects of NRF-1 and PGC-1α cooperation on HIF-1α and rat cardiomyocyte apoptosis under hypoxia. HIF-1alpha
12  2022 Hen Egg Lysozyme Alleviates Static Mechanical Pain Via NRF1-Parkin-TACAN Signaling Axis in Sensory Neurons. CFA, DRG, HEL, SNL
13  2022 NRF1-mediated microglial activation triggers high-altitude cerebral edema. AP2B1, BBB, Cav-1, HACE, NF-kappaB p65
14  2022 NRG1/ErbB2 axis regulated mitochondrial function and antioxidant enzymes of neural stem cells in the cochlear nucleus partially through PGC-1α. Drp1, Fis1, GSH-Px, Mfn, MnSOD, mt, NRG1, NSCs, PGC-1alpha, SOD, TFAM
15  2022 Nuclear Respiratory Factor 1 Overexpression Inhibits Proliferation and Migration of PC3 Prostate Cancer Cells. ---
16  2022 Nuclear respiratory factor 1 promotes the growth of liver hepatocellular carcinoma cells via E2F1 transcriptional activation. ChIP-seq, LIHC
17  2022 Nuclear respiratory factor 1 transcriptomic signatures as prognostic indicators of recurring aggressive mesenchymal glioblastoma and resistance to therapy in White American females. BANJO, GBM, MCMC, miRNA
18  2022 Oxygen as an important factor modulating in vitro MeHgCl toxicity associated with mitochondrial genes in hiPSCs. hiPSCs, TFAM
19  2022 Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway. ERalpha, Fis1, Mfn1, Mfn2, MYH3, MyoG, PNF, TNF-alpha
20  2022 PBDE-47 induces impairment of mitochondrial biogenesis and subsequent neurotoxicity through miR-128-3p/PGC-1α axis. mtDNA, PGC-1alpha
21  2022 Pseudoautosomal Region 1 Overdosage Affects the Global Transcriptome in iPSCs From Patients With Klinefelter Syndrome and High-Grade X Chromosome Aneuploidies. HGAs, iPSCs, KS, PAR1, XIST, ZFX
22  2022 Psoralidin protects against cerebral hypoxia/reoxygenation injury: Role of GAS6/Axl signaling. Bcl-2, Gas6, HO-1, HR, LDH, NQO1, NRF2, PSO, ROS, SIRT1, UCP2
23  2022 Resveratrol Attenuates Hyperoxia Lung Injury in Neonatal Rats by Activating SIRT1/PGC-1α Signaling Pathway. DMSO, mtDNA, PGC-1alpha, RES, SIRT1
24  2022 Role of PGC-1α in fiber type conversion in the palatopharyngeus muscle of OSA patients. OSA, PGC-1alpha
25  2022 Salvianolic acid A promotes mitochondrial biogenesis and function via regulating the AMPK/PGC-1α signaling pathway in HUVECs. ACC, AMPK, HUVECs, SAA
26  2022 Salvianolic acid A promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes through regulation of the AMPK-PGC1α signalling pathway. mtDNA, PGC-1alpha, SAA, WAT
27  2022 SGLT2i reduces renal injury by improving mitochondrial metabolism and biogenesis. AKI, AMPKalpha1, PGC1alpha
28  2022 Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice. CAT, CK, ER, HE, IL-6, LDH, MDA, PGC-1alpha, SA, SOD, STZ, T-AOC, TNF-a
29  2022 Sulforaphane Increase Mitochondrial Biogenesis-Related Gene Expression in the Hippocampus and Suppresses Age-Related Cognitive Decline in Mice. NF-E2, PGC1alpha, SAMP8, SAMR1, SFN
30  2022 Sulforaphane Protects against Unilateral Ureteral Obstruction-Induced Renal Damage in Rats by Alleviating Mitochondrial and Lipid Metabolism Impairment. ACO2, Bcl-2, CD36, CIII, DGAT1, Drp1, FASN, PGC-1alpha, SFN, SREBP1, TG, UUO, VDAC
31  2022 Targeting phase separation on enhancers induced by transcription factor complex formations as a new strategy for treating drug-resistant cancers. AR, FOXA1, IDRs, LLPS, PC, SEs, TFs
32  2022 Transcriptional regulation of NRF1 on metabotropic glutamate receptors in a neonatal hypoxic‑ischemic encephalopathy rat model. HIE, iGluRs, mGluRs
33  2022 Yixin Ningshen Tablet Alleviates Comorbidity of Myocardial Infarction and Depression by Enhancing Myocardial Energy Metabolism and Increasing Availability of Monoamine Neurotransmitter. 5-HT, ACTH, AMPK, CORT, IL, KMO, KYNU, MI, NE, PGC-1alpha, TNF-alpha, YXNS
34  2022 [Nuclear respiratory factor 1 mediates LPS-induced acute lung injury through NF-κB]. ChIP, IL-1beta, LPS, NF-kappaB
35  2021 AFB1-induced mice liver injury involves mitochondrial dysfunction mediated by mitochondrial biogenesis inhibition. AFB1, ATP, cyt c, dUTP, ETC, MMP, PGC-1alpha, TCA, VDAC1
36  2021 An N-ethyl-N-Nitrosourea Mutagenesis Screen in Mice Reveals a Mutation in Nuclear Respiratory Factor 1 (Nrf1) Altering the DNA Methylation State and Correct Embryonic Development. ENU, GFP
37  2021 ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. ATG, TF, TMA
38  2021 Chemical Inhibition of Apurinic-Apyrimidinic Endonuclease 1 Redox and DNA Repair Functions Affects the Inflammatory Response via Different but Overlapping Mechanisms. 8-oxoG, AP sites, BER, LPS, MX
39  2021 DMEP induces mitochondrial damage regulated by inhibiting Nrf2 and SIRT1/PGC-1alpha signaling pathways in HepG2 cells. AST, DMEP, HO-1, IL-1beta, IL-6, MDA, mtDNA, NAC, NF-kappaB, Nrf2, PGC-1alpha, ROS, SIRT1, TNF-alpha
40  2021 Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management. DNMT1, DOX, HDAC, PGC
41  2021 Effect of DEHP and DnOP on mitochondrial damage and related pathways of Nrf2 and SIRT1/PGC-1α in HepG2 cells. AST, DEHP, HO-1, LC3II, MDA, Nrf2, PGC-1alpha, SIRT1
42  2021 Effects of Nrf1 in Hypothalamic Paraventricular Nucleus on Regulating the Blood Pressure During Hypertension. AAV, GABA, Glu, NE, NMDAR, PVN, ROS, shNrf1, SHR
43  2021 FNDC5 expression closely correlates with muscle fiber types in porcine longissimus dorsi muscle and regulates myosin heavy chains (MyHCs) mRNA expression in C2C12 cells. CK, DLY, FNDC5, LD, MDH, MyHC, MyHCs, SDH, VEGF
44  2021 Glucocorticoid transiently upregulates mitochondrial biogenesis in the osteoblast. DEX, GC, Mfn2, OPA1
45  2021 Identification of Distant Regulatory Elements Using Expression Quantitative Trait Loci Mapping for Heat-Responsive Genes in Oysters. ATG7, eQTL, HSP, RPL10A, SNPs
46  2021 Intermittent hypoxia preconditioning protects WRL68 cells against oxidative injury: Involvement of the PINK1/Parkin-mediated mitophagy regulated by nuclear respiratory factor 1. IH
47  2021 Knockdown of lncRNA NORAD inhibits the proliferation, inflammation and fibrosis of human mesangial cells under high-glucose conditions by regulating the miR-485/NRF1 axis. DN, FN, HG, HMCs, IL, lncRNAs, miR-485, NORAD, PAI-1, RT-qPCR, TNF
48  2021 Latent Membrane Protein 1 Promotes Tumorigenesis Through Upregulation of PGC1β Signaling Pathway. EBV, GABPalpha, HKDC1, LMP1, NF-kappaB, NKTCL, PPARgamma, ROS, VDAC1
49  2021 Mitophagy receptor FUNDC1 is regulated by PGC-1α/NRF1 to fine tune mitochondrial homeostasis. ---
50  2021 Mulberry leaf activates brown adipose tissue and induces browning of inguinal white adipose tissue in type 2 diabetic rats through regulating AMP-activated protein kinase signalling pathway. AMPK, BAT, CPT-1, iWAT, PGC-1alpha, PPARalpha, PRDM16, T2DM, TMEM26, UCP1
51  2021 Nesfatin-1 alleviates high glucose/high lipid-induced injury of trophoblast cells during gestational diabetes mellitus. GDM, HG, HL
52  2021 NRF-1 directly regulates TFE3 and promotes the proliferation of renal cancer cells. RCC, shRNA, TFE3
53  2021 NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain. PRC1
54  2021 Nrf1 Knock-Down in the Hypothalamic Paraventricular Nucleus Alleviates Hypertension Through Intervention of Superoxide Production-Removal Balance and Mitochondrial Function. cyt c, GCLC, Mfn1, NE, NQO1, PGC-1alpha, PRDX3, PVN
55  2021 Nuclear factor erythroid 2-related factor 2 protects bovine mammary epithelial cells against free fatty acid-induced mitochondrial dysfunction in vitro. FFA, mtDNA, NFE2L2, PGC-1alpha, ROS, SFN, si-Control, si-NFE2L2
56  2021 Nuclear respiratory factor 1 protects H9C2 cells against hypoxia-induced apoptosis via the death receptor pathway and mitochondrial pathway. MMP, ROS
57  2021 Nuclear Respiratory Factor-1, a Novel SMAD4 Binding Protein, Represses TGF-beta/SMAD4 Signaling by Functioning as a Transcriptional Cofactor. TGF-beta
58  2021 Quercetin-mediated SIRT1 activation attenuates collagen-induced mice arthritis. CIA, ERK, HMGB1, PGC-1alpha, QUE, RA, SIRT1, TCM, TLR4
59  2021 Relationship Between Myocardial Injury and Expression of PGC-1α and Its Coactivators in Chronic Keshan Disease. ERRalpha, KD, LDH, PPAR
60  2021 Resveratrol Improves Mitochondrial Biogenesis Function and Activates PGC-1alpha Pathway in a Preclinical Model of Early Brain Injury Following Subarachnoid Hemorrhage. EBI, MDA, PGC-1alpha, ROS, RSV, SAH, SOD
61  2021 Subtype-specific collaborative transcription factor networks are promoted by OCT4 in the progression of prostate cancer. AR, CRPC, PC, TFs
62  2021 Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats. AKI, AMI, ATP, CsA, Drp1, IR, MMP, mPTP, PGC-1, RCR, ROS, TFam, TIIA
63  2021 Temporal characterization of mitochondrial impairment in the unilateral ureteral obstruction model in rats. CKD, OXPHOS, PGC-1alpha, PINK1, UUO
64  2021 Testosterone attenuates hypoxia-induced hypertension by affecting NRF1-mediated transcriptional regulation of ET-1 and ACE. ACE, Ang-2, BP, ET-1, HARs
65  2021 Testosterone attenuates pulmonary epithelial inflammation in male rats of COPD model through preventing NRF1-derived NF-κB signaling. COPD, CSE, LPS
66  2021 Validation of novel hub genes and molecular mechanisms in acute lung injury using an integrative bioinformatics approach. ALI, CoDEGs, Csf2, LPS, TFs
67  2021 ZNF746/PARIS promotes the occurrence of hepatocellular carcinoma. DEN, HCC, PARIS, PGC-1alpha, ZNF746
68  2021 [Hypoxia Accelerate beta-Actin Expression through Transcriptional Activation of ACTB by Nuclear Respiratory Factor-1]. ACTB
69  2021 β2-adrenoreceptor agonist ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of mitochondrial biogenesis. ADRB2, mtDNA, PINP, PWTs
70  2020 Alteration of the Mitochondrial Effects of Ceria Nanoparticles by Gold: An Approach for the Mitochondrial Modulation of Cells Based on Nanomedicine. ATP, NFE2L1
71  2020 ATF4 activation promotes hepatic mitochondrial dysfunction by repressing NRF1-TFAM signalling in alcoholic steatohepatitis. AH, ALD, ATF4
72  2020 Betulinic Acid Inhibits Endometriosis Through Suppression of Estrogen Receptor beta Signaling Pathway. BA, COX-2, ERbeta, MMP-1, SOD2
73  2020 Catalpol promotes mitochondrial biogenesis in chondrocytes. ATP, CREB, PGC-1alpha, Tomm22, Tomm70
74  2020 Cerebral Mitochondrial Function and Cognitive Performance during Aging: A Longitudinal Study in NMRI Mice. CAT, Creb1, GAP43, PGC1alpha, SOD2, SYP1
75  2020 Estrogenic control of mitochondrial function. ECAR, OCR, PGC-1alpha
76  2020 Evaluation of boscalid toxicity on Daphnia magna by using antioxidant enzyme activities, the expression of genes related to antioxidant and detoxification systems, and life-history parameters. CAT, Cyp4, D. magna, GST, MDA, SOD
77  2020 Huoxue Huatan Decoction Ameliorates Myocardial Ischemia/Reperfusion Injury in Hyperlipidemic Rats via PGC-1α-PPARα and PGC-1α-NRF1-mtTFA Pathways. CHO, CK-MB, Cu,Zn-SOD, GSH-Px, HDL-C, HXHT, I/R, LDH, LDL-C, MDA, mtDNA, mtTFA, PGC-1alpha, PPARalpha, SDH, T-SOD, TG
78  2020 Identification of microRNA‑363‑3p as an essential regulator of chondrocyte apoptosis in osteoarthritis by targeting NRF1 through the p53‑signaling pathway. IL, LPS, miR, miRNA, OA
79  2020 IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3beta-Nrf2-BNIP3 Pathway. BNIP3, GSK-3beta, HIF-1alpha, MEFs
80  2020 Increased Insulin Sensitivity by High-Altitude Hypoxia in Mice with High-Fat Diet-Induced Obesity Is Associated with Activated AMPK Signaling and Subsequently Enhanced Mitochondrial Biogenesis in Skeletal Muscles. AMPK, CPT1, HFD, p-Akt, p-AMPK, PGC-1alpha
81  2020 Integrated Chip-Seq and RNA-Seq Data Analysis Coupled with Bioinformatics Approaches to Investigate Regulatory Landscape of Transcription Modulators in Breast Cancer Cells. ID3
82  2020 Is the secret of VDAC Isoforms in their gene regulation? Characterization of human VDAC genes expression profile, promoter activity, and transcriptional regulators. CAGE, EBOX, KLFS, TFBSs
83  2020 Mangiferin induces the expression of a thermogenic signature via AMPK signaling during brown-adipocyte differentiation. CIDEA, COX-2, COX7A, DIO2, MF, PGC1alpha, PPARalpha and gamma, PRDM16, SIRT1
84  2020 Metabolic disturbance in Korean red ginseng-induced "Shanghuo" (excessive heat). AMP, AMPK, KRG, PGC-1alpha, SDH
85  2020 Nuclear respiratory factor 1 (NRF-1) upregulates the expression and function of reduced folate carrier (RFC) at the blood-brain barrier. BBB, ChIP, CSF, FRalpha, PCFT, PQQ, RFC, VDR
86  2020 Nuclear Respiratory Factor 1 (NRF1) Transcriptional Activity-Driven Gene Signature Association with Severity of Astrocytoma and Poor Prognosis of Glioblastoma. ---
87  2020 Nup133 and ERalpha mediate the differential effects of hyperoxia-induced damage in male and female OPCs. ERalpha, OPCs
88  2020 Perindopril Improves Cardiac Function by Enhancing the Expression of SIRT3 and PGC-1alpha in a Rat Model of Isoproterenol-Induced Cardiomyopathy. HF, ISO, PER, PGC-1alpha, ROS, SIRT3
89  2020 Selenium supplementation during pregnancy and lactation promotes metabolic changes in Wistar rats' offspring. BAT, DIO, PGC-1alpha, Se, THs, WAT
90  2020 Sensitivity to differential NRF1 gene signatures contributes to breast cancer disparities. BANJO, MCMC, TN
91  2020 SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride. PGC-1alpha, RSV, SIRT1
92  2020 Songorine promotes cardiac mitochondrial biogenesis via Nrf2 induction during sepsis. CRAC, LPS, OXPHOS, ROS, TCA
93  2020 Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1alpha pathway. DDR, PGC-1alpha
94  2020 The hypoglycemic mechanism of catalpol involves increased AMPK-mediated mitochondrial biogenesis. AMPK
95  2020 The PGC1alpha/NRF1-MPC1 axis suppresses tumor progression and enhances the sensitivity to sorafenib/doxorubicin treatment in hepatocellular carcinoma. HCC, MPC1, PGC1alpha, ROS
96  2020 [Down-regulation of SIRT1 and PGC-1alpha expression caused by hyperoxia induces mitochondrial dysfunction in human alveolar epithelial cells]. mitoROS
97  2020 [Effect of mogroside VI on acute liver injury induced by sepsis in mice and related mechanisms]. AST, GSH-Px, MDA, mtDNA, MVI, PGC-1alpha, SOD
98  2019 Arginine promotes porcine type I muscle fibres formation through improvement of mitochondrial biogenesis. Arg, cyt c, MyHC I, PGC-1alpha, ROT
99  2019 Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism. ANP, AS-IV, BNP, cyt c, LVEDP, LVSP, LVW/HW
100  2019 Beneficial effects of PGC-1alpha in the substantia nigra of a mouse model of MPTP-induced dopaminergic neurotoxicity. ERRalpha, i.p, MPTP, NRF-2, NS, PGC-1alpha, PPARgamma, SN, SOD