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■ Abbreviation / Long Form : PGC1alpha / PPARgamma coactivator 1alpha

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Total Number of Papers: 67
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Abbreviation:   PGC1alpha  (>> Co-occurring Abbreviation)
Long Form:   PPARgamma coactivator 1alpha
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No. Year Title Co-occurring Abbreviation
1  2022 Chronic nitrate administration increases the expression the genes involved in the browning of white adipose tissue in female rats. mRNA, NO, PPARgamma, UCP1, WAT
2  2022 Xyloketal B Reverses Nutritional Hepatic Steatosis, Steatohepatitis, and Liver Fibrosis through Activation of the PPARalpha/PGC1alpha Signaling Pathway. FAO, HFD, MCD, NAFLD, PPARalpha, Xyl-B
3  2021 18:0 Lyso PC, a natural product with potential PPAR-gamma agonistic activity, plays hypoglycemic effect with lower liver toxicity and cardiotoxicity in db/db mice. ACC, AMP, PPARgamma, T2DM, UCP1
4  2021 Caloric restriction and Roux-en-Y Gastric Bypass promote white adipose tissue browning in mice. CR, HFD, NRF1, RYGB, UCP1, WAT
5  2021 D-Mannitol Induces a Brown Fat-like Phenotype via a beta3-Adrenergic Receptor-Dependent Mechanism. AMPK, CPT1, PKA, UCP1
6  2021 Fruit of Gardenia jasminoides Induces Mitochondrial Activation and Non-Shivering Thermogenesis through Regulation of PPARgamma. GJFE, PPARgamma, UCP1
7  2021 Nobiletin Attenuates Pathological Cardiac Remodeling after Myocardial Infarction via Activating PPARgamma and PGC1alpha. HO-1, Nrf2, NRVMs, PPARgamma, qRT-PCR, TUNEL, WB
8  2021 PEX13 is required for thermogenesis of white adipose tissue in cold-exposed mice. BAT, beta3AR, NST, PEXs, PPARgamma, SVF, UCP1, WAT
9  2021 White Adipose Tissue Depots Respond to Chronic Beta-3 Adrenergic Receptor Activation in a Sexually Dimorphic and Depot Divergent Manner. ERbeta, GRP75, UCP1, WAT
10  2020 Adipose tissue gene expression of long non-coding RNAs; MALAT1, TUG1 in obesity: is it associated with metabolic profile and lipid homeostasis-related genes expression? ACC, BMI, FAS, MALAT1, PPARgamma, SAT, SREBP-1c, TUG1, VAT, WC
11  2020 Long-term nitrate administration increases expression of browning genes in epididymal adipose tissue of male type 2 diabetic rats. cGMP, CN, DN, EAT, PPARgamma, T2D, UCP1
12  2020 PPARGC1A gene polymorphism is associated with exercise-induced fat loss. ANOVA, PPARgamma
13  2020 Purified Gymnemic Acids from Gymnema inodorum Tea Inhibit 3T3-L1 Cell Differentiation into Adipocytes. GI, UCP1
14  2020 Regulation of Lin28a-miRNA let-7b-5p pathway in skeletal muscle cells by peroxisome proliferator-activated receptor delta. HFD, PPARdelta, TR
15  2020 WY14643 improves left ventricular myocardial mitochondrial and systolic functions in obese rats under chronic persistent hypoxia via the PPARalpha pathway. ACC2, CPT1alpha, HFD, PPAR
16  2019 A novel specific peroxisome proliferator-activated receptor gamma (PPARgamma) modulator YR4-42 ameliorates hyperglycaemia and dyslipidaemia and hepatic steatosis in diet-induced obese mice. DIO, PPARgamma, TRAP220
17  2019 Hyperoxia improves carbohydrate metabolism by browning of white adipocytes in obese type 2 diabetic rats. PPARgamma, UCP1
18  2019 Maternal Eicosapentaenoic Acid Feeding Decreases Placental Lipid Deposition and Improves the Homeostasis of Oxidative Stress Through a Sirtuin-1 (SIRT1) Independent Manner. EPA, SIRT1, T-SOD, UCP1
19  2019 PGC1alpha Suppresses Prostate Cancer Cell Invasion through ERRalpha Transcriptional Control. ---
20  2019 The effect of antecedent-conditioning high-intensity interval training on BDNF regulation through PGC-1alpha pathway following cerebral ischemia. HIIT, MCAO
21  2018 Berberine Protects Against Palmitate-Induced Apoptosis in Tubular Epithelial Cells by Promoting Fatty Acid Oxidation. BBR, CKD, CPT1A, FAO, PA, PPARalpha, TECs
22  2018 Hepatocyte ALOXE3 is induced during adaptive fasting and enhances insulin sensitivity by activating hepatic PPARgamma. ---
23  2018 Lithocholic Acid Improves the Survival of Drosophila Melanogaster. LCA, srl
24  2018 MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-alpha signalling in beige adipocytes. iWAT, UCP1
25  2018 Nuciferine ameliorates hepatic steatosis in high-fat diet/streptozocin-induced diabetic mice through a PPARalpha/PPARgamma coactivator-1alpha pathway. HFD, STZ, T2DM
26  2017 Dysregulation of mitochondrial function and biogenesis modulators in adipose tissue of obese children. ATP, CI, CS, MB, mtDNA, PPARgamma, SIRT1, SOD2
27  2017 PPARgamma Regulates Mitochondrial Structure and Function and Human Pulmonary Artery Smooth Muscle Cell Proliferation. HPASMC, PASMC, PH, PPARgamma
28  2017 PPARgamma-Coactivator-1alpha, Nicotinamide Adenine Dinucleotide and Renal Stress Resistance. AKI
29  2017 [Expressions of inflammatory and fibrogenic factors in perinephric and subcutaneous adipose tissues of patients with adrenocorticotropic hormone-independent Cushing's syndrome]. ACTH, CEBPbeta, CIDEA, Egr-1, IL-6, MMP-2, peri-N, TIMP1, TNF-alpha, UCP1
30  2016 Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption. ACSL, ACSL5, FACoA, FGF21, UCP1
31  2016 Altered PPARgamma Coactivator-1 Alpha Expression in Abdominal Aortic Aneurysm: Possible Effects on Mitochondrial Biogenesis. AAA, Ang, VSMCs
32  2016 Molecular profiling of dilated cardiomyopathy that progresses to heart failure. DCM, HCM, HF, LV, TBX-15
33  2016 Perfluorooctanesulfonate Mediates Renal Tubular Cell Apoptosis through PPARgamma Inactivation. ChIP, PFCs, PFOS, PPRE, RTCs
34  2016 PPARalpha-ATGL pathway improves muscle mitochondrial metabolism: implication in aging. ATGL, PPARalpha
35  2016 The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction. ---
36  2015 Activation of peroxisome proliferator-activated receptor alpha stimulates ADAM10-mediated proteolysis of APP. AD, ADAM10, APP, PPARalpha
37  2015 Asparagine attenuates intestinal injury, improves energy status and inhibits AMP-activated protein kinase signalling pathways in weaned piglets challenged with Escherichia coli lipopolysaccharide. AMPKalpha1, Asn, LPS, SIRT1
38  2015 Green Tea Polyphenols Attenuate High-Fat Diet-Induced Renal Oxidative Stress through SIRT3-Dependent Deacetylation. CON, GTPs, HF, MDA, MnSOD, PPAR, SIRT3
39  2015 Sarcolipin Is a Key Determinant of the Basal Metabolic Rate, and Its Overexpression Enhances Energy Expenditure and Resistance against Diet-induced Obesity. PPARdelta, SLN
40  2015 Sensing and responding to energetic stress: The role of the AMPK-PGC1alpha-NRF1 axis in control of mitochondrial biogenesis in fish. AMPK, NRF1
41  2015 Tang-Nai-Kang alleviates pre-diabetes and metabolic disorders and induces a gene expression switch toward fatty acid oxidation in SHR.Cg-Leprcp/NDmcr rats. ACC, AMPK, SIRT1, TNK
42  2014 Relaxin activates peroxisome proliferator-activated receptor gamma (PPARgamma) through a pathway involving PPARgamma coactivator 1alpha (PGC1alpha). CREB, PKA, PPARgamma
43  2014 Syzygium aromaticum L. (Clove) extract regulates energy metabolism in myocytes. ACC, AMPK, SIRT1
44  2014 The circadian clock machinery controls adiponectin expression. PPARgamma, SREBP
45  2013 Influence of pregnancy in mid-to-late gestation on circulating metabolites, visceral organ mass, and abundance of proteins relating to energy metabolism in mature beef cows. AMPK, BHBA, p-AMPK, PCNA, PEPCK, PREG, UCP2
46  2013 Mechanisms of resveratrol-induced inhibition of clonal expansion and terminal adipogenic differentiation in 3T3-L1 preadipocytes. AMPK
47  2013 Rosemary (Rosmarinus officinalis L.) extract regulates glucose and lipid metabolism by activating AMPK and PPAR pathways in HepG2 cells. ACC, AMPK, G6Pase, LDLR
48  2012 A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. ---
49  2012 Dietary obesity-associated Hif1alpha activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system. HIF1alpha, SIRT2
50  2012 Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation. ACC1, ADRP, ER, FIT2, FSP27, LXRalpha, PPARgamma, SCD1, TG, TM, UPR, XBP1
51  2011 Brown fat biology and thermogenesis. ATP, BMP-7, PET/CT, PRDM16, SNS, UCP1
52  2011 Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice. CDE, NAFLD, NRF1
53  2011 PGC1alpha promotes tumor growth by inducing gene expression programs supporting lipogenesis. ---
54  2010 Berberine Moderates Glucose and Lipid Metabolism through Multipathway Mechanism. AUC, CEBP, FBG, FINS, GLUT4, HDL-C, HNF4alpha, HOMA-IR, LDL-C, MAPK14, OGTT, PPARalpha, TC, TG, UCP2
55  2010 Human NPC1L1 expression is positively regulated by PPARalpha. EMSAs, NPC1L1, PPARalpha, PPRE
56  2010 Infusion of a lipid emulsion modulates AMPK and related proteins in rat liver, muscle, and adipose tissues. ACC, AdipoR1, CaMKK, LE, PP2C, SREBP-1c
57  2010 Two weekly sessions of combined aerobic and resistance exercise are sufficient to provide beneficial effects in subjects with Type 2 diabetes mellitus and metabolic syndrome. CPT-1, FOXO-1, GLUT4, IRS-1, LPL, PPAR, RM
58  2009 Conjugated linoleic acid induces uncoupling protein 1 in white adipose tissue of ob/ob mice. CLA, CON, CPT1b, eWAT, MAPK, UCP1, WAT
59  2009 Metoprolol represses PGC1alpha-mediated carnitine palmitoyltransferase-1B expression in the diabetic heart. CPT-1, PPAR-alpha, USF2
60  2009 PPARdelta and PGC1alpha act cooperatively to induce haem oxygenase-1 and enhance vascular endothelial cell resistance to stress. PPARs
61  2009 Rosiglitazone increases the expression of peroxisome proliferator-activated receptor-gamma target genes in adipose tissue, liver, and skeletal muscle in the sheep fetus in late gestation. G3PDH, LPL, PEPCK, PPARgamma
62  2006 Anti-obesity effect of Pinellia ternata extract in Zucker rats. BAT, PE, PPARalpha, UCP1, WAT
63  2006 Calcineurin regulates skeletal muscle metabolism via coordinated changes in gene expression. PPARs
64  2006 CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD. CLA, DSS, IBD, KGF, PPARgamma, PUFA, UCP3
65  2006 Control of mitochondrial biogenesis during myogenesis. CS, NRF1
66  2006 Dietary soya protein intake and exercise training have an additive effect on skeletal muscle fatty acid oxidation enzyme activities and mRNA levels in rats. CPT1, HAD
67  2005 A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro. PPARgamma, TG