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■ Abbreviation / Long Form : PI3K / PIK3CA

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Total Number of Papers: 21
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Abbreviation:   PI3K  (>> Co-occurring Abbreviation)
Long Form:   PIK3CA
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No. Year Title Co-occurring Abbreviation
2021 Allicin protects against myocardial I/R by accelerating angiogenesis via the miR-19a-3p/PI3K/AKT axis. MI/R, qPCR
2020 Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. TNBC, YB-1
2019 Distinct roles of PIK3CA in the enrichment and maintenance of cancer stem cells in head and neck squamous cell carcinoma. CSCs, Ephs, HNSCC, RTKs, TRK
2019 PIK3CA and MAP3K1 alterations imply luminal A status and are associated with clinical benefit from pan-PI3K inhibitor buparlisib and letrozole in ER+ metastatic breast cancer. HER2
2017 Specific gene expression signatures induced by the multiple oncogenic alterations that occur within the PTEN/PI3K/AKT pathway in lung cancer. AKT1, DEGs, IPA
2014 MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway. 3'-UTR, ASM, HASM
2013 Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R. ---
2013 Genetically engineered mouse models of PI3K signaling in breast cancer. GEMMs
2012 An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice. ---
10  2011 The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation. PIK3C3
11  2010 Relative quantification of PIK3CA gene expression level in fine-needle aspiration biopsy thyroid specimens collected from patients with papillary thyroid carcinoma and non-toxic goitre by real-time RT-PCR. FNAB, NTG, PTC
12  2009 Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance. ---
13  2009 PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches. PI3Ks
14  2008 Characterization of PI3K class IA isoforms with regulatory subunit p55alpha using a scintillation proximity assay. SPA
15  2008 Dysregulation of the phosphatidylinositol 3-kinase pathway in thyroid neoplasia. PTEN
16  2008 Expressional changes in the intracellular melanogenesis pathways and their possible role in the pathogenesis of vitiligo. ---
17  2007 Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern. EN, FGFR3, SK
18  2007 Patterns of PIK3CA alterations in familial colorectal and endometrial carcinoma. CRC, EC, MMR
19  2005 Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells. ---
20  2005 High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma. ---
21  2005 PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. ER/PR