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■ Abbreviation / Long Form : PPT / protein precipitation

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Total Number of Papers: 43
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Abbreviation:   PPT  (>> Co-occurring Abbreviation)
Long Form:   protein precipitation
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No. Year Title Co-occurring Abbreviation
2022 Comprehensive Evaluation of Blood Plasma and Serum Sample Preparations for HRMS-Based Chemical Exposomics: Overlaps and Specificities. LC-HRMS, PLR, SLE, SPE, SPM
2021 An improved sample extraction method reveals that plasma receptor for advanced glycation end-products (RAGE) modulates circulating free oxytocin in mice. ELISAs, KO, OT, RAGE, RIA, WT
2021 Improving LC-MS analysis of human milk B-vitamins by lactose removal. LSE, SPE
2021 Simultaneous and rapid determination of 12 tyrosine kinase inhibitors by LC-MS/MS in human plasma: Application to therapeutic drug monitoring in patients with non-small cell lung cancer. ESI, MRM, NSCLC, SALLE, TDM, TKIs
2021 Simultaneous LC-MS/MS bioanalysis of alkaloids, terpenoids, and flavonoids in rat plasma through salting-out-assisted liquid-liquid extraction after oral administration of extract from Tetradium ruticarpum and Glycyrrhiza uralensis: a sample preparation strategy to broaden analyte coverage of herbal medicines. LLE, SALLE, SULLE
2020 A simple and sensitive HPLC-FL method for simultaneous determination of angiotensin II receptor antagonists in human plasma. LLE, MEPS
2020 Extensive evaluation of sample preparation workflow for gas chromatography-mass spectrometry-based plasma metabolomics and its application in rheumatoid arthritis. LLE, MSTFA, RA, SPE, TMCS
2020 Optimizing sample preparation workflow for bioanalysis of oligonucleotides through liquid chromatography tandem mass spectrometry. LLE, SPE
2020 Salting Out-Assisted Liquid-Liquid Extraction for Liquid Chromatography-Tandem Mass Spectrometry Measurement of Tacrolimus, Sirolimus, Everolimus, and Cyclosporine a in Whole Blood. SALLE
10  2019 Effective quantification of 11 tyrosine kinase inhibitors and caffeine in human plasma by validated LC-MS/MS method with potent phospholipids clean-up procedure. Application to therapeutic drug monitoring. CML, mu-SPE, TDM, TKIs
11  2019 Proteinase K Combining Two-Step Liquid-Liquid Extraction for Plasma Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics To Discover the Potential Mechanism of Colorectal Adenoma. LLE, PK
12  2019 Simultaneous Determination of Seven Active Components in Rat Plasma by UHPLC-MS/MS and Application to a Quantitative Study after Oral Administration of Huang-Lian Jie-Du Decoction in High Fat-Induced Atherosclerosis Rats. HLJDD, IS, MRM
13  2019 Simultaneous determination of six antipsychotics, two of their metabolites and caffeine in human plasma by LC-MS/MS using a phospholipid-removal microelution-solid phase extraction method for sample preparation. ARI, CAF, CLO, DARI, OLA, PAL, QUE, RIS
14  2019 Simultaneous determination of tenofovir alafenamide and tenofovir in human plasma by LC-MS/MS and its application to pharmacokinetics study in clinic. ESI, MRM, TAF, TFV
15  2018 A Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Nimbolide in Mouse Serum: Application to a Preclinical Pharmacokinetics Study. IS, MRM
16  2018 Simultaneous analysis of allopurinol and oxypurinol using a validated liquid chromatography-tandem mass spectrometry method in human plasma. ---
17  2017 Application of a rapid mu-SPE clean-up for multiclass quantitative analysis of sixteen new psychoactive substances in whole blood by LC-MS/MS. mu-SPE, NPS, SC, WB
18  2017 Comparison of efficiencies of selected sample extraction techniques for the analysis of selected antiretroviral drugs in human plasma using LC-MS. LE
19  2017 UPLC-ESI-MS/MS study of the effect of green tea extract on the oral bioavailability of erlotinib and lapatinib in rats: Potential risk of pharmacokinetic interaction. ERL, GEF, GT, GTP, LAP, LLOQ, MRM, PK, SPE, TKIs
20  2017 Utility of Cremophor RH 40 as a micellar improvement for spectrofluorimetric estimation of sorafenib in pure form, commercial preparation, and human plasma. Cr RH 40, SOR
21  2016 Development and Validation of a Sensitive and Specific LC-MS-MS Method for the Determination of Acotiamide in Rat Plasma. FD
22  2016 LC-MS Method for Studying the Pharmacokinetics and Bioequivalence of Clonidine Hydrochloride in Healthy Male Volunteers. ESI, LOQ
23  2015 A rapid and sensitive LC-MS/MS method for the determination of linarin in small-volume rat plasma and tissue samples and its application to pharmacokinetic and tissue distribution study. LLE
24  2015 An UPLC-MS/MS method for quantitative profiling of bile acids in sea lamprey plasma and tissues. BAs, LOD
25  2015 LC-MS/MS analysis of pramipexole in mouse plasma and tissues: elimination of lipid matrix effects using weak cation exchange mode based solid-phase extraction. CNS, GPChos, Lyso-GPChos, SPE
26  2015 The absolute bioavailability investigation of LS177 in rats using ultra-performance liquid chromatography-tandem mass spectrometry. LLE, MET
27  2014 A new approach for plasma (xeno)metabolomics based on solid-phase extraction and nanoflow liquid chromatography-nanoelectrospray ionisation mass spectrometry. LC-MS, nUHPLC-nESI-TOFMS, SPE
28  2014 Development of a highly sensitive liquid chromatography/tandem mass spectrometry method to quantify total and free levels of a target protein, interferon-gamma-inducible protein-10, at picomolar levels in human serum. IP-10, LLOQ, SRM
29  2014 Evaluation of human plasma sample preparation protocols for untargeted metabolic profiles analyzed by UHPLC-ESI-TOF-MS. SPE
30  2014 Hydrophilic interaction liquid chromatography-solid phase extraction directly combined with protein precipitation for the determination of triptorelin in plasma. HILIC-SPE, RPLC
31  2012 Liquid chromatography and tandem mass spectrometry method for the quantitative determination of saxagliptin and its major pharmacologically active 5-monohydroxy metabolite in human plasma: method validation and overcoming specific and non-specific binding at low concentrations. ---
32  2012 Quantification of monoamine neurotransmitters and melatonin in sea lamprey brain tissues by high performance liquid chromatography-electrospray ionization tandem mass spectrometry. CV, MRM, NTs, PFHA, SPE
33  2012 Systematic evaluation of supported liquid extraction in reducing matrix effect and improving extraction efficiency in LC-MS/MS based bioanalysis for 10 model pharmaceutical compounds. LLE, PL, SLE
34  2011 Quantitative analysis of PD 0332991 in mouse plasma using automated micro-sample processing and microbore liquid chromatography coupled with tandem mass spectrometry. AUC, CDK4, CL, PK, PK/PD, Vd
35  2011 Simultaneous determination of flucloxacillin and ampicillin in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and subsequent application to a clinical study in healthy Chinese volunteers. LLOQ, MRM
36  2010 Determination of ethyl glucuronide in hair samples of Chinese people by protein precipitation (PPT) and large volume injection-gas chromatography-tandem mass spectrometry (LVI-GC/MS/MS). EtG, RSD
37  2010 Immunoaffinity purification using anti-PEG antibody followed by two-dimensional liquid chromatography/tandem mass spectrometry for the quantification of a PEGylated therapeutic peptide in human plasma. CV, HPLC, IAP
38  2009 A flexible and high throughput liquid chromatography-tandem mass spectrometric assay for the quantitation of telcagepant in human plasma. APCI, CGRP, CV, IS
39  2009 High-performance liquid chromatography-tandem mass spectrometry for the determination of pidotimod in human plasma and its application to a pharmacokinetic study. ESI, IS, LLOQ, MRM, QC
40  2008 Simultaneous quantification of enalapril and enalaprilat in human plasma by high-performance liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study. ESI, LLOQ, MRM
41  2007 Systematic and comprehensive strategy for reducing matrix effects in LC/MS/MS analyses. ESI, LLE, MRM, SPE
42  2002 Determination of cefaclor in human plasma by a sensitive and specific liquid chromatographic-tandem mass spectrometric method. ESI, QC, SPE, SRM
43  2001 Comparison of manual protein precipitation (PPT) versus a new small volume PPT 96-well filter plate to decrease sample preparation time. ---