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■ Abbreviation / Long Form : PRCP / prolylcarboxypeptidase

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Total Number of Papers: 64
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Abbreviation:   PRCP  (>> Co-occurring Abbreviation)
Long Form:   prolylcarboxypeptidase
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No. Year Title Co-occurring Abbreviation
2021 Alterations in Gene Expression of Renin-Angiotensin System Components and Related Proteins in Colorectal Cancer. Ang, ANPEP, GEO, PREP, THOP
2021 Prolyl Carboxypeptidase Mediates the C-Terminal Cleavage of (Pyr)-Apelin-13 in Human Umbilical Vein and Aortic Endothelial Cells. ACE2
2021 The C-terminal cleavage of angiotensin II and III is mediated by prolyl carboxypeptidase in human umbilical vein and aortic endothelial cells. ACE2, HUVEC and HAoEC, PREP
2020 Dysregulated activities of proline-specific enzymes in septic shock patients (sepsis-2). AUC, DPP4, FAP, ICU, PREP, ROC
2020 Genetic association study of prolylcarboxypeptidase polymorphisms with susceptibility to essential hypertension in the Yi minority of China: A case-control study based on an isolated population. BP, CI, EH, OR
2020 Haplotype-based association study between PRCP gene polymorphisms and essential hypertension in Hani minority group from a remote region of China. BP, EH, KKS, RAAS, SNPs
2020 Prolylcarboxypeptidase Mitigates Myocardial Ischemia/Reperfusion Injury by Stabilizing Mitophagy. AMI, I/R
2019 A genomic prediction model for racecourse starts in the Thoroughbred horse. NTM, OPCML, RFME
2018 Prolyl carboxypeptidase activity in the circulation and its correlation with body weight and adipose tissue in lean and obese subjects. ---
10  2018 Prolyl carboxypeptidase in Agouti-related Peptide neurons modulates food intake and body weight. alpha-MSH
11  2017 Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis. CAP1, IgAN, SHC1
12  2017 Prolylcarboxypeptidase (PrCP) inhibitors and the therapeutic uses thereof: a patent review. KKS, POMC, RAS
13  2017 Prolylcarboxypeptidase deficiency is associated with increased blood pressure, glomerular lesions, and cardiac dysfunction independent of altered circulating and cardiac angiotensin II. Ang II, BP, LVH, MAP
14  2016 A Cross-sectional Study of KLKB1 and PRCP Polymorphisms in Patient Samples with Cardiovascular Disease. CI, CVD, OR, PK, PTCA
15  2016 Dysregulation of the renin-angiotensin system during lung ischemia-reperfusion injury. Ang-2, LIRI, PREP
16  2015 Loss of prolyl carboxypeptidase in two-kidney, one-clip goldblatt hypertensive mice. Ang
17  2015 Prolylcarboxypeptidase gene expression in the heart and kidney: Effects of obesity and diabetes. alpha-MSH, Ang II, Ang III, HFD, ZDF
18  2014 Deficient prolylcarboxypeptidase gene and protein expression in left ventricles of spontaneously hypertensive rats (SHR). LVH, SHR
19  2014 Prolyl carboxypeptidase activity decline correlates with severity and short-term outcome in acute ischemic stroke. mRS, NIHSS
20  2014 Pyrazoles as non-classical bioisosteres in prolylcarboxypeptidase (PrCP) inhibitors. ---
21  2014 The prolyl peptidases PRCP/PREP regulate IRS-1 stability critical for rapamycin-induced feedback activation of PI3K and AKT. mTOR, PI3K, PREP, RTKs
22  2013 A digestive prolyl carboxypeptidase in Tenebrio molitor larvae. ---
23  2013 Discovery and optimization of orally active cyclohexane-based prolylcarboxypeptidase (PrCP) inhibitors. ---
24  2013 Ghrelin regulates hypothalamic prolyl carboxypeptidase expression in mice. alpha-MSH
25  2013 PRCP regulates angiogenesis in vivo. ---
26  2013 Prolyl carboxypeptidase mRNA expression in the mouse brain. ---
27  2013 Prolylcarboxypeptidase promotes angiogenesis and vascular repair. eNOS, hPRCPmut, KLF, PECAM
28  2013 [Effect of losartan on the protection of the kidney and PRCP-kallikrein axis of the two-kidney, one-clipped renovascular hypertensive rats]. BUN, SD
29  2012 A new class of prolylcarboxypeptidase inhibitors, part 1: discovery and evaluation. PO
30  2012 A new class of prolylcarboxypeptidase inhibitors, part 2: the aminocyclopentanes. ---
31  2012 Angiotensin II type 2 receptor-stimulated activation of plasma prekallikrein and bradykinin release: role of SHP-1. ECs, SBTI, siRNA
32  2012 Association of polymorphisms in prolylcarboxypeptidase and chymase genes with essential hypertension in the Chinese Han population. Ang II, CI, EH, OR, SNPs
33  2012 Deletion of prolyl carboxypeptidase attenuates the metabolic effects of diet-induced obesity. alpha-MSH, HFD, SD
34  2012 Discovery of a new class of potent prolylcarboxypeptidase inhibitors derived from alanine. ---
35  2012 Discovery of aminoheterocycles as potent and brain penetrant prolylcarboxypeptidase inhibitors. ---
36  2012 Discovery of benzodihydroisofurans as novel, potent, bioavailable and brain-penetrant prolylcarboxypeptidase inhibitors. eDIO, SAR
37  2012 Influence of a novel inhibitor (UM8190) of prolylcarboxypeptidase (PRCP) on appetite and thrombosis. BK, HPAEC, PK, rPRCP
38  2012 Plasma prolylcarboxypeptidase (angiotensinase C) is increased in obesity and diabetes mellitus and related to cardiovascular dysfunction. PIVUS
39  2012 Prolyl carboxypeptidase and its inhibitors in metabolism. alpha-MSH, POMC
40  2011 Discovery of benzimidazole pyrrolidinyl amides as prolylcarboxypeptidase inhibitors. ---
41  2011 Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis. ROS
42  2011 Prolyl carboxypeptidase regulates energy expenditure and the thyroid axis. alpha-MSH, WT
43  2011 The discovery of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors. eDIO, P-gp
44  2010 Design and synthesis of prolylcarboxypeptidase (PrCP) inhibitors to validate PrCP as a potential target for obesity. ---
45  2010 E112D polymorphism in the prolylcarboxypeptidase gene is associated with blood pressure response to benazepril in Chinese hypertensive patients. ---
46  2010 Expression, purification and crystallization of human prolylcarboxypeptidase. ---
47  2010 Highly selective hydrolysis of kinins by recombinant prolylcarboxypeptidase. rPRCP
48  2010 New aspects of melanocortin signaling: a role for PRCP in alpha-MSH degradation. alpha-MSH, MCRs, POMC
49  2010 Peptidomic profiling of human cerebrospinal fluid identifies YPRPIHPA as a novel substrate for prolylcarboxypeptidase. ---
50  2010 Prolylcarboxypeptidase (PRCP) as a new target for obesity treatment. alpha-MSH, POMC
51  2010 Prolylcarboxypeptidase regulates proliferation, autophagy, and resistance to 4-hydroxytamoxifen-induced cytotoxicity in estrogen receptor-positive breast cancer cells. TAM
52  2010 S28 peptidases: lessons from a seemingly 'dysfunctional' family of two. DPP7
53  2009 Prolylcarboxypeptidase regulates food intake by inactivating alpha-MSH in rodents. ---
54  2009 Reduced levels of neurotransmitter-degrading enzyme PRCP promote a lean phenotype. [corrected]. alpha-MSH
55  2009 Upregulation of prolylcarboxypeptidase (PRCP) in lipopolysaccharide (LPS) treated endothelium promotes inflammation. Ang 1-7, BK, ELISA, HUVEC, LPS
56  2008 Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats. Ang
57  2008 Prolylcarboxypeptidase: a cardioprotective enzyme. Ang II, Ang III, PK
58  2008 The functional importance of the N-terminal region of human prolylcarboxypeptidase. Ang 1-7, Ang 2-7, Ang I, Ang II, Ang III, CD
59  2007 Glucocorticoids plus opioids up-regulate genes that influence neuronal function. MPHOSPH9, RT-PCR, ZFP95
60  2007 Identification of lipopolysaccharide binding site on high molecular weight kininogen. BK, HK, KKS
61  2004 Recombinant prolylcarboxypeptidase activates plasma prekallikrein. DFP, EDTA, HK, HUVECs, PK, PMSF, rPRCP
62  2002 Assembly and activation of the plasma kallikrein/kinin system: a new interpretation. FXI, FXII, HK, KKS, PK, RAS
63  2002 Identification and characterization of prolylcarboxypeptidase as an endothelial cell prekallikrein activator. HUVEC, PK, PKA
64  1998 Cellular carboxypeptidases. CPs