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■ Abbreviation / Long Form : RGS2 / regulator of G-protein signaling 2

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Total Number of Papers: 149
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Abbreviation:   RGS2  (>> Co-occurring Abbreviation)
Long Form:   regulator of G-protein signaling 2
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
1  2022 Endothelial Natriuretic Peptide Receptor 1 Play Crucial Role for Acute and Chronic Blood Pressure Regulation by Atrial Natriuretic Peptide. ANP, NPR1
2  2022 Regulator of G protein signaling 2 inhibits Gαq-dependent uveal melanoma cell growth. UM
3  2022 The Association of RGS2 and Slug in the Androgen-induced Acquisition of Mesenchymal Features of Breast MDA-MB-453 Cancer Cells. AR, DHT, EMT, LAR
4  2021 Effect of the regulator of G-protein signaling 2 on the proliferation and invasion of oral squamous cell carcinoma cells and its molecular mechanism. CCK, Co-IP, DDB1, FHL1, OSCC
5  2021 Reduced Blood RGS2 Expression in Mild Cognitive Impairment Patients. AD, MCI, qRT-PCR
6  2021 RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse. ATF4, NSCLC, SCCs
7  2021 The histone deacetylase inhibitor PCI-24781 impairs calcium influx and inhibits proliferation and metastasis in breast cancer. HDACs
8  2021 The Increased Expression of Regulator of G-Protein Signaling 2 (RGS2) Inhibits Insulin-Induced Akt Phosphorylation and Is Associated with Uncontrolled Glycemia in Patients with Type 2 Diabetes. HDL, HUVEC-CS, PA, PCA, RSG2, T2DM
9  2021 ZHX3 promotes the progression of urothelial carcinoma of the bladder via repressing of RGS2 and is a novel substrate of TRIM21. Co-IP, MS, TRIM21, UCB, ZHX3
10  2020 IL-33/ST2 signaling modulates Afghanistan particulate matter induced airway hyperresponsiveness in mice. AHR, APM, DRLD, KO, PM, WT
11  2020 N-Terminal Targeting of Regulator of G Protein Signaling Protein 2 for F-Box Only Protein 44-Mediated Proteasomal Degradation. FBXO44, RGS
12  2020 RGS2 is prognostic for development of castration resistance and cancer-specific survival in castration-resistant prostate cancer. ADT, AR, CRPC, FFS, PC, PSA
13  2020 Silencing of RGS2 enhances hippocampal neuron regeneration and rescues depression-like behavioral impairments through activation of cAMP pathway. ---
14  2020 Soluble silica stimulates osteogenic differentiation and gap junction communication in human dental follicle cells. COMP, Cx43, HDFC, MMPs, NGS, OIM, RGS4, Si
15  2019 Loss-of-Function Mutations in Human Regulator of G Protein Signaling RGS2 Differentially Regulate Pharmacological Reactivity of Resistance Vasculature. ACh, LOF, MAs, PKG, WT
16  2019 Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice. HDAC9, RGS
17  2019 RGS2 promotes the translation of stress-associated proteins ATF4 and CHOP via its eIF2B-inhibitory domain. RGS2eb
18  2019 RGS2: A multifunctional signaling hub that balances brown adipose tissue function and differentiation. BAT, EE, GPCRs, WT
19  2018 Analysis of regulator of G-protein signalling 2 (RGS2) expression and function during prostate cancer progression. PC
20  2018 Downregulation of regulator of G protein signaling 2 expression in breast invasive carcinoma of no special type: Clinicopathological associations and prognostic relevance. BIC-NST
21  2018 Establishing a Split Luciferase Assay for Proteinkinase G (PKG) Interaction Studies. cGMP, PCA, PKG, PPI
22  2018 In Vitro Transcriptome Response to a Mixture of Lactobacilli Strains in Intestinal Porcine Epithelial Cell Line. AXIN2, GM-CSF, IL-18, IL-20, LB, OSM
23  2018 Interplay between RGS2 and childhood adversities in predicting anxiety and depressive disorders: Findings from a general population sample. GE, OR
24  2018 Luteinizing Hormone Receptor Gene and Regulator of G-protein Signaling 2 Gene Expression Level and Association with Oocyte Maturity in In vitro Fertilization/Intracytoplasmic Sperm Injection Cycle. CCMII, COC, LHR
25  2018 Mechanistic role of the CREB-regulated transcription coactivator 1 in cardiac hypertrophy. CRTC1
26  2018 Regulation of the regulator of G protein signaling 2 expression and cellular localization by PKA and PKC pathways in mouse granulosa cells. GPCR
27  2018 Regulator of G protein signaling 2 differentially regulates nicotine-induced anxiolytic- and antidepressant-like effects in mice. KO, WT
28  2018 Uterine RGS2 expression is regulated by exogenous estrogen and progesterone in ovariectomized mice, and downregulation of RGS2 expression in artificial decidualized ESCs inhibits trophoblast spreading in vitro. ---
29  2018 [Association between C1114G polymorphism in the regulator of G protein signaling 2 and vasovagal syncope in children]. HUT, VVS
30  2017 Cardiomyocyte specific overexpression of a 37 amino acid domain of regulator of G protein signalling 2 inhibits cardiac hypertrophy and improves function in response to pressure overload in mice. ANP, eIF2B, MHC-beta, RGS2eb TG, TAC, WT
31  2017 Epigenetic regulation of RGS2 (Regulator of G-protein signaling 2) in chemoresistant ovarian cancer cells. GPCRs, HDACs
32  2017 Human Missense Mutations in Regulator of G Protein Signaling 2 Affect the Protein Function Through Multiple Mechanisms. AT1R, WT
33  2017 Increased fear learning, spatial learning as well as neophobia in Rgs2-/- mice. ---
34  2017 Intracellular interactions of umeclidinium and vilanterol in human airway smooth muscle. ASMCs, beta2R, cAMP, MCh, UMEC
35  2017 Protective Roles for RGS2 in a Mouse Model of House Dust Mite-Induced Airway Inflammation. GPCRs, HDM, ICSs, LABAs
36  2017 Proteolytic degradation of regulator of G protein signaling 2 facilitates temporal regulation of Gq/11 signaling and vascular contraction. ---
37  2017 Regulator of G protein signaling 2 is a key regulator of pancreatic beta-cell mass and function. GPCR
38  2017 Specific protein biomarker patterns for Alzheimer's disease: improved diagnostics in progress. AD, ADNP
39  2016 A switch in G protein coupling for type 1 corticotropin-releasing factor receptors promotes excitability in epileptic brains. CRF
40  2016 An RGS2 3'UTR polymorphism is associated with preeclampsia in overweight women. FINNPEC
41  2016 Post-cocaine changes in regulator of G-protein signaling (RGS) proteins in the dorsal striatum: Relevance for cocaine-seeking and protein kinase C-mediated phosphorylation. dSTR, RGS
42  2016 Regulator of G protein signaling 2 (Rgs2) regulates neural crest development through Ppardelta-Sox10 cascade. ---
43  2016 RGS2 modulates the activity and internalization of dopamine D2 receptors in neuroblastoma N2A cells. D2Rs, N2A
44  2016 The angiotensin II receptor antagonist, losartan, enhances regulator of G protein signaling 2 mRNA expression in vascular smooth muscle cells of Wistar rats. Ang II, AT1R, AT2R, ATR
45  2016 Understanding how long-acting beta2 -adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids in asthma - an update. ASM, DUSP1, ICS
46  2016 Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis. ---
47  2015 FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex. CUL4B, DDB1, FBXO44
48  2015 MicroRNA hsa-miR-4717-5p regulates RGS2 and may be a risk factor for anxiety-related traits. ACQ, ASI, MIR4717
49  2015 Regulation of Renal Hemodynamics and Function by RGS2. ENaC, GFR, GPCR, L-NAME, RBF, RPP, RVR, WT
50  2015 Regulator of G-protein signaling 2 (RGS2) suppresses premature calcium release in mouse eggs. ACh, MII
51  2015 RGS2 ggenetic variation: association analysis with panic disorder and dimensional as well as intermediate phenotypes of anxiety. ACQ, BAT, PD
52  2015 The RGS2 (-391, C>G) genetic variation correlates to antihypertensive drug responses in Chinese patients with essential hypertension. ANOVA, BP, PCR-RFLP
53  2014 Amphetamine self-administration attenuates dopamine D2 autoreceptor function. AMPH, DA, NAcc, VTA
54  2014 Enhanced proliferation and altered calcium handling in RGS2-deficient vascular smooth muscle cells. MTT, PDGF, PMCA4, RGS2KO, SERCA2, VSMC, WT
55  2014 Expression and regulation of regulator of G-protein signaling protein-2 (RGS2) in equine and bovine follicles prior to ovulation: molecular characterization of RGS2 transactivation in bovine granulosa cells. hCG
56  2014 Identification of protein kinase C activation as a novel mechanism for RGS2 protein upregulation through phenotypic screening of natural product extracts. GPCRs, PKC
57  2014 Impaired regulator of G protein signaling 2 transcription facilitates vascular remodeling in injured rat aorta. VSMCs
58  2014 Knockdown of regulator of G-protein signalling 2 (Rgs2) leads to abnormal early mouse embryo development in vitro. si
59  2014 Regulator of G protein signaling 2 (RGS2) and RGS4 form distinct G protein-dependent complexes with protease activated-receptor 1 (PAR1) in live cells. BRET, GPCR, PAR1, RGS
60  2014 Regulator of G protein signaling 2 (RGS2) deficiency accelerates the progression of kidney fibrosis. Ang II, UUO
61  2014 Regulator of G-protein signaling 2 (RGS2) in cardiology and oncology. ---
62  2014 RGS2 suppresses breast cancer cell growth via a MCPIP1-dependent pathway. GAP, MCPIP1, TSPYL5
63  2014 The eIF2B-interacting domain of RGS2 protects against GPCR agonist-induced hypertrophy in neonatal rat cardiomyocytes. ---
64  2014 Upregulation of regulator of G-protein signaling 2 in the sclera of a form deprivation myopic animal model. FDM
65  2014 [Polymorphism of RGS2 gene: genetic markers of risk for schizophrenia and pharmacogenetic markers of typical neuroleptics efficiency]. ---
66  2013 Adrenomedullin and adrenotensin increase the transcription of regulator of G‑protein signaling 2 in vascular smooth muscle cells via the cAMP‑dependent and PKC pathways. ADM, ADT, PKA, VSMCs
67  2013 An intrinsic CRF signaling system within the optic tectum. GABA
68  2013 Anti-inflammatory glucocorticoids: changing concepts. AP-1, GPCRs, NF-kappaB
69  2013 Dynamics of Galphaq-protein-p63RhoGEF interaction and its regulation by RGS2. ---
70  2013 Functional role, mechanisms of regulation, and therapeutic potential of regulator of G protein signaling 2 in the heart. RGS proteins
71  2013 MicroRNA-22 (miR-22) overexpression is neuroprotective via general anti-apoptotic effects and may also target specific Huntington's disease-related mechanisms. 3-NP, HDAC4, miR-22, miRNAs, RCOR1, Tp53inp1
72  2013 PP084. Hypertension after preeclampsia in women with C1114G polymorphism in rgs2 (the regulator of g protein signaling 2). ---
73  2013 RGS2 is a feedback inhibitor of melatonin production in the pineal gland. ---
74  2013 Single nucleotide polymorphisms in G protein signaling pathway genes in preeclampsia. AGTR1
75  2013 Stress-induced transcription of regulator of G protein signaling 2 (RGS2) by heat shock transcription factor HSF1. ---
76  2013 Structural and functional analysis of the regulator of G protein signaling 2-galphaq complex. GAP
77  2012 Cardiotonic steroids stabilize regulator of G protein signaling 2 protein levels. CTSs
78  2012 Knockdown of receptor-interacting serine/threonine protein kinase-2 (RIPK2) affects EMT-associated gene expression in human hepatoma cells. EMT, FGFBP1, HepG2-shRIPK2, JAG1, KRT19, NF-kappaB, PAI-1, RIPK2, SIP1, SNAI2, VIM
79  2012 Regulator of G protein signaling 2 deficiency causes endothelial dysfunction and impaired endothelium-derived hyperpolarizing factor-mediated relaxation by dysregulating Gi/o signaling. EDHF, NO
80  2012 Regulator of G protein signaling 2 is a key modulator of airway hyperresponsiveness. AHR, ASM
81  2012 Regulator of G-protein signaling 2 inhibits acid-induced mucin5AC hypersecretion in human airway epithelial cells. MUC5AC, OGR1
82  2012 RGS2 mediates the anxiolytic effect of oxytocin. CeA, CNS, OT
83  2011 Alteration in RGS2 expression level is associated with changes in haloperidol induced extrapyramidal features in a mutant mouse model. AIP, HET, HOM, WT
84  2011 Association of intima-media thickening of carotid artery with genetic polymorphisms of the regulator of G-protein signaling 2 gene in patients with hypertension and in the general population. CI, M-IMT, OR
85  2011 Association of RGS2 variants with panic disorder in a Japanese population. PD, SNPs
86  2011 beta2-Adrenoceptor agonist-induced RGS2 expression is a genomic mechanism of bronchoprotection that is enhanced by glucocorticoids. ---
87  2011 Characterization of age-related gene expression profiling in bone marrow and epididymal adipocytes. FABP4, GPR109A, IL-6, PPARgamma, SFRP4, TGF-beta1, TNF-alpha
88  2011 Detection of genetic variations of regulator of G-protein signaling 2 in hypertensives by sequencing. ---
89  2011 Gene expression in the adrenal glands of three spontaneously hypertensive rat substrains. APLN, BP, EPHX2, GJA1, IGF1R, KYNU, M-SHRSP, SHR, UTS2, WKY
90  2011 Identification of a cAMP-response element in the regulator of G-protein signaling-2 (RGS2) promoter as a key cis-regulatory element for RGS2 transcriptional regulation by angiotensin II in cultured vascular smooth muscles. Ang II, CRE, CREB, PKC, VSMC
91  2011 RGS2 is a negative regulator of STAT3-mediated Nox1 expression. MyD88, Nox1, PKC-eta, PLD2, STAT3, TLR
92  2011 RGS2 is a primary terminator of beta₂-adrenergic receptor-mediated G(i) signaling. beta-AR
93  2011 Rgs2 mediates pro-angiogenic function of myeloid derived suppressor cells in the tumor microenvironment via upregulation of MCP-1. MDSCs
94  2011 RGS2-mediated intracellular Ca2+ level plays a key role in the intracellular replication of Brucella abortus within phagocytes. BAPTA-AM, EDTA
95  2010 Association of genetic variations of regulator of G-protein signaling 2 with hypertension in the general Xinjiang Kazakh population. SBP
96  2010 Further evidence supporting a role for gs signal transduction in severe malaria pathogenesis. ADCY9, ADRBK1, GNB3, Gs
97  2010 Impact of RGS2 deficiency on the therapeutic effect of telmisartan in angiotensin II-induced aortic aneurysm. Ang II
98  2010 Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study. Ca
99  2010 Protein kinase C-eta and phospholipase D2 pathway regulates foam cell formation via regulator of G protein signaling 2. LPS, PKC, PLD, siRNA, TLR
100  2010 RGS2 inhibits beta-adrenergic receptor-induced cardiomyocyte hypertrophy. alpha1A-R, beta-AR, ET-1, ISO