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■ Abbreviation / Long Form : RIPK2 / receptor-interacting protein kinase 2

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Total Number of Papers: 18
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Abbreviation:   RIPK2  (>> Co-occurring Abbreviation)
Long Form:   receptor-interacting protein kinase 2
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No. Year Title Co-occurring Abbreviation
2022 Design, synthesis, and structure-activity relationship of novel RIPK2 inhibitors. ---
2022 NOD/RIPK2 signalling pathway contributes to osteoarthritis susceptibility. NOD, OA, PTOA
2022 Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis. MKK7, PC
2021 Design of pyrido[2,3-d]pyrimidin-7-one inhibitors of receptor interacting protein kinase-2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling. ALK2, NOD
2021 Receptor-interacting protein kinase 2 contributes to host innate immune responses against Fusobacterium nucleatum in macrophages and decidual stromal cells. APOs, BMDMs, F. nucleatum, hDSCs, NO, NOD, WT
2021 The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease. IBD
2020 ASC-deficiency impairs host defense against Aeromonas hydrophila infection in Japanese medaka, Oryzias latipes. KO, NF-kappaB, WT
2020 Gefitinib Inhibits Invasion and Metastasis of Osteosarcoma via Inhibition of Macrophage Receptor Interacting Serine-Threonine Kinase 2. ---
2020 Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold. ALK2, NOD
10  2019 A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. CSCs, GBM
11  2019 RIPK2-Mediated Autophagy and Negatively Regulated ROS-NLRP3 Inflammasome Signaling in GMCs Stimulated with High Glucose. DN, GMCs, HG
12  2018 A hyperactivating proinflammatory RIPK2 allele associated with early-onset osteoarthritis. OA
13  2018 Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors. ---
14  2018 Computational design of new protein kinase 2 inhibitors for the treatment of inflammatory diseases using QSAR, pharmacophore-structure-based virtual screening, and molecular dynamics. MLR, SEE
15  2018 Flaxseed Oil Attenuates Intestinal Damage and Inflammation by Regulating Necroptosis and TLR4/NOD Signaling Pathways Following Lipopolysaccharide Challenge in a Piglet Model. ALA, DHA, EPA, LPS, MyD88, NF-kappaB, NOD1, NOD2, PUFAs, TLR4
16  2017 Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. NOD2, VLS
17  2015 A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production. NOD
18  2009 Febrile seizures: characterization of double-stranded RNA-induced gene expression. CASP1, GABRE, IL-26, TLR4, TNF