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■ Abbreviation / Long Form : RTX / repeats-in-toxin

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Total Number of Papers: 106
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Abbreviation:   RTX  (>> Co-occurring Abbreviation)
Long Form:   repeats-in-toxin
 Abbreviation Variation
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No. Year Title Co-occurring Abbreviation
2021 Almost half of the RTX domain is dispensable for complement receptor 3 binding and cell-invasive activity of the Bordetella adenylate cyclase toxin. CR3
2021 Cholesterol stimulates the lytic activity of Adenylate Cyclase Toxin on lipid membranes by promoting toxin oligomerization and formation of pores with a greater effective size. ACT
2021 MALDI-TOF MS Biomarker Detection Models to Distinguish RTX Toxin Phenotypes of Moraxella bovoculi Strains Are Enhanced Using Calcium Chloride Supplemented Agar. TSA
2020 Acyltransferase-mediated selection of the length of the fatty acyl chain and of the acylation site governs activation of bacterial RTX toxins. ACPs, HlyA
2020 Aggregatibacter actinomycetemcomitans leukotoxin: From mechanism to targeted anti-toxin therapeutics. LFA-1
2020 Calcium-Induced Activity and Folding of a Repeat in Toxin Lipase from Antarctic Pseudomonas fluorescens Strain AMS8. CD, DLS, FTIR, ITC
2020 Cell wall surface layer (S-layer) promotes colony formation in Microcystis: comparison of S-layer characteristics between colonial and unicellular forms of Microcystis and function conformation. S-layer, S-layer
2020 Continuous Assembly of β-Roll Structures Is Implicated in the Type I-Dependent Secretion of Large Repeat-in-Toxins (RTX) Proteins. ---
2020 Identification of a large repetitive RTX immunogen in a highly virulent Rodentibacter heylii strain. RhiA
10  2020 Membrane Activity and Channel Formation of the Adenylate Cyclase Toxin (CyaA) of Bordetella pertussis in Lipid Bilayer Membranes. AC
11  2020 Phylogenetic Analysis of Filifactor alocis Strains Isolated from Several Oral Infections Identified a Novel RTX Toxin, FtxA. LDH
12  2020 Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme-translocating segment of Bordetella adenylate cyclase toxin. AC, HlyA
13  2020 Structural Basis of Ca2+-Dependent Self-Processing Activity of Repeat-in-Toxin Proteins. Asp-Pro, Ca-SPM, SPM
14  2020 The Influence of Calcium toward Order/Disorder Conformation of Repeat-in-Toxin (RTX) Structure of Family I.3 Lipase from Pseudomonas fluorescens AMS8. MD
15  2019 Genetics, Toxicity, and Distribution of Enterohemorrhagic Escherichia coli Hemolysin. EHEC, HC, HUS, LEE, Stx
16  2019 Rapid Purification of Endotoxin-Free RTX Toxins. HlyA, T1SS
17  2019 RTX Toxins Ambush Immunity's First Cellular Responders. ---
18  2019 The Extracellular Domain of the beta2 Integrin beta Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity. ---
19  2018 Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough. ---
20  2018 Comparative analysis of humoral immune responses and pathologies of BALB/c and C57BL/6 wildtype mice experimentally infected with a highly virulent Rodentibacter pneumotropicus (Pasteurella pneumotropica) strain. Ig, Th
21  2018 Conserved structural features anchor biofilm-associated RTX-adhesins to the outer membrane of bacteria. RI, RIN
22  2018 Detection of Actinobacillus Pleuropneumoniae ApxIV Toxin Antibody in Serum and Oral Fluid Specimens from Pigs Inoculated Under Experimental Conditions. dpi, ELISAs, LPS
23  2018 Membrane localization of the Repeats-in-Toxin (RTX) Leukotoxin (LtxA) produced by Aggregatibacter actinomycetemcomitans. LFA-1
24  2018 Receptor-Based Peptides for Inhibition of Leukotoxin Activity. LAP, LFA-1
25  2018 Structural requirement of the hydrophobic region of the Bordetella pertussis CyaA-hemolysin for functional association with CyaC-acyltransferase in toxin acylation. ---
26  2018 Type 1 Does the Two-Step: Type 1 Secretion Substrates with a Functional Periplasmic Intermediate. BTLCP, T1SS
27  2018 Using single molecule force spectroscopy to facilitate a rational design of Ca2+-responsive beta-roll peptide-based hydrogels. ---
28  2018 Whole genome sequencing of Moraxella bovoculi reveals high genetic diversity and evidence for interspecies recombination at multiple loci. IBK, SNP
29  2017 Block V RTX Domain of Adenylate Cyclase from Bordetella pertussis: A Conformationally Dynamic Scaffold for Protein Engineering Applications. ---
30  2017 Catch and Release: Engineered Allosterically Regulated beta-Roll Peptides Enable On/Off Biomolecular Recognition. ---
31  2017 Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates. AC-Hly, PTMs
32  2017 Conditional Network Assembly and Targeted Protein Retention via Environmentally Responsive, Engineered beta-Roll Peptides. ---
33  2017 Fine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin. ACT
34  2017 Functional Contributions of Positive Charges in the Pore-Lining Helix 3 of the Bordetella pertussis CyaA-Hemolysin to Hemolytic Activity and Ion-Channel Opening. CyaA-Hly, PLBs
35  2017 Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems. Bap, CDI
36  2017 Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis. ---
37  2017 Structure-Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes. cAMP
38  2017 Zn2+-dependent autocatalytic activity of the Bordetella pertussis CyaA-hemolysin. CyaA-Hly
39  2015 Interdomain Contacts and the Stability of Serralysin Protease from Serratia marcescens. ---
40  2015 Isolated CyaA-RTX subdomain from Bordetella pertussis: Structural and functional implications for its interaction with target erythrocyte membranes. CyaA-Hly, sRBC
41  2015 Kingella kingae: carriage, transmission, and disease. ---
42  2015 Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion. ---
43  2015 The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies. ---
44  2014 Boundary region between coexisting lipid phases as initial binding sites for Escherichia coli alpha-hemolysin: a real-time study. BAM, HlyA, Ld
45  2014 Doubling the cross-linking interface of a rationally designed beta roll peptide for calcium-dependent proteinaceous hydrogel formation. MBP
46  2014 Equilibrium folding of pro-HlyA from Escherichia coli reveals a stable calcium ion dependent folding intermediate. T1SS
47  2014 Genomics and host specialization of honey bee and bumble bee gut symbionts. ---
48  2014 Hemolysin of enterohemorrhagic Escherichia coli: structure, transport, biological activity and putative role in virulence. EHEC, EHEC-Hly, Ehx, HUS, OMVs
49  2014 Inducible polymerization and two-dimensional assembly of the repeats-in-toxin (RTX) domain from the Pseudomonas aeruginosa alkaline protease. ---
50  2014 The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies. ACT
51  2014 Virulence genes in clinical and environmental Stenotrophomas maltophilia isolates: a genome sequencing and gene expression approach. ---
52  2013 A designed, phase changing RTX-based peptide for efficient bioseparations. AdhD, GFP, MBP
53  2013 Aggregatibacter actinomycetemcomitans leukotoxin utilizes a cholesterol recognition/amino acid consensus site for membrane association. CRAC, LFA-1
54  2013 Differences in purinergic amplification of osmotic cell lysis by the pore-forming RTX toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the role of pore size. PPADS
55  2013 Enterohemorrhagic Escherichia coli hemolysin employs outer membrane vesicles to target mitochondria and cause endothelial and epithelial apoptosis. EHEC, EHEC-Hly, HBMEC, OMVs
56  2013 Genetic and phenotypic analysis of Vibrio cholerae non-O1, non-O139 isolated from German and Austrian patients. MARTX, MS, TCP, TTSS
57  2013 Molecular crowding stabilizes both the intrinsically disordered calcium-free state and the folded calcium-bound state of a repeat in toxin (RTX) protein. ---
58  2013 Self-assembly of pH and calcium dual-responsive peptide-amphiphilic hydrogel. ---
59  2013 Simultaneous detection of antibodies against Apx toxins ApxI, ApxII, ApxIII, and ApxIV in pigs with known and unknown Actinobacillus pleuropneumoniae exposure using a multiplexing liquid array platform. CFT, ELISAs, FMIA
60  2012 Identification of the minimal region in lipase ABC transporter recognition domain of Pseudomonas fluorescens for secretion and fluorescence of green fluorescent protein. EGF, GFP, LARDs, T1SS
61  2012 Leukotoxin from Aggregatibacter actinomycetemcomitans causes shrinkage and P2X receptor-dependent lysis of human erythrocytes. PS
62  2012 Mannheimia haemolytica and its leukotoxin cause macrophage extracellular trap formation by bovine macrophages. LKT, MET, NETs
63  2012 Monodisperse and LPS-free Aggregatibacter actinomycetemcomitans leukotoxin: interactions with human beta2 integrins and erythrocytes. SRCD
64  2012 Re-evaluation of a bacterial antifreeze protein as an adhesin with ice-binding activity. AFPs, RII, RIV
65  2012 Rearranging and concatenating a native RTX domain to understand sequence modularity. ---
66  2011 Aggregatibacter actinomycetemcomitans leukotoxin is post-translationally modified by addition of either saturated or hydroxylated fatty acyl chains. ---
67  2011 Aggregatibacter actinomycetemcomitans leukotoxin: a powerful tool with capacity to cause imbalance in the host inflammatory response. ---
68  2011 Calcium-induced folding and stabilization of the Pseudomonas aeruginosa alkaline protease. AP
69  2011 Calcium-induced folding of intrinsically disordered repeat-in-toxin (RTX) motifs via changes of protein charges and oligomerization states. ---
70  2011 Ehrlichia chaffeensis tandem repeat proteins and Ank200 are type 1 secretion system substrates related to the repeats-in-toxin exoprotein family. TRP
71  2011 Influences of ORF1 on the virulence and immunogenicity of Actinobacillus pleuropneumoniae. ---
72  2011 Predicting genetic traits and epitope analysis of apxIVA in Actinobacillus pleuropneumoniae. ---
73  2011 Presence of putative repeat-in-toxin gene tosA in Escherichia coli predicts successful colonization of the urinary tract. UPEC, UTIs
74  2011 Structure and function of MARTX toxins and other large repetitive RTX proteins. ---
75  2011 The repeat-in-toxin family member TosA mediates adherence of uropathogenic Escherichia coli and survival during bacteremia. UPEC, UTI
76  2010 Bordetella pertussis CyaA-RTX subdomain requires calcium ions for structural stability against proteolytic degradation. CyaA-PF
77  2010 Calcium-induced folding and stabilization of the intrinsically disordered RTX domain of the CyaA toxin. RD
78  2010 Characterization of the regions involved in the calcium-induced folding of the intrinsically disordered RTX motifs from the bordetella pertussis adenylate cyclase toxin. RD
79  2010 Crystallization and preliminary crystallographic characterization of the iron-regulated outer membrane lipoprotein FrpD from Neisseria meningitidis. FrpD, SeMet FrpD43-271
80  2010 RTX proteins: a highly diverse family secreted by a common mechanism. ---
81  2009 A FRET-based method for probing the conformational behavior of an intrinsically disordered repeat domain from Bordetella pertussis adenylate cyclase. FRET
82  2009 Bordetella adenylate cyclase toxin promotes calcium entry into both CD11b+ and CD11b- cells through cAMP-dependent L-type-like calcium channels. ACT
83  2009 Cloning and characterization of a novel cysteine protease gene (HbCP1) from Hevea brasiliensis. gran, RACE
84  2009 Regulation of the type I protein secretion system by the MisR/MisS two-component system in Neisseria meningitidis. EMSA
85  2009 Vesicular stabilization and activity augmentation of enterohaemorrhagic Escherichia coli haemolysin. OMVs
86  2008 RTX calcium binding motifs are intrinsically disordered in the absence of calcium: implication for protein secretion. RD
87  2007 A Ca2+-dependent bacterial antifreeze protein domain has a novel beta-helical ice-binding fold. ---
88  2007 Aggregatibacter actinomycetemcomitans leukotoxin requires beta-sheets 1 and 2 of the human CD11a beta-propeller for cytotoxicity. LFA-1, Ltx
89  2007 Human CD18 is the functional receptor for Aggregatibacter actinomycetemcomitans leukotoxin. LFA-1
90  2007 The TolC-like protein of neisseria meningitidis is required for extracellular production of the repeats-in-toxin toxin FrpC but not for resistance to antimicrobials recognized by the Mtr efflux pump system. ---
91  2006 Bordetella adenylate cyclase toxin: a swift saboteur of host defense. ---
92  2006 Identification of an RTX determinant of Burkholderia cenocepacia J2315 by subtractive hybridization. ---
93  2006 Purification and characterization of a hemolysin-like protein, Sll1951, a nontoxic member of the RTX protein family from the Cyanobacterium Synechocystis sp. strain PCC 6803. GT, HLP
94  2005 Gram-negative bacterial ATP-binding cassette protein exporter family and diverse secretory proteins. ABC
95  2005 The CD11a partner in Sus scrofa lymphocyte function-associated antigen-1 (LFA-1): mRNA cloning, structure analysis and comparison with mammalian homologues. LFA-1
96  2005 The Escherichia coli Hemolysin. ---
97  2005 Unusual genetic organization of a functional type I protein secretion system in Neisseria meningitidis. TOSS
98  2004 A novel "clip-and-link" activity of repeat in toxin (RTX) proteins from gram-negative pathogens. Covalent protein cross-linking by an Asp-Lys isopeptide bond upon calcium-dependent processing at an Asp-Pro bond. ---
99  2003 Genetic and biochemical characterization of PrtA, an RTX-like metalloprotease from Photorhabdus. INH
100  2002 The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model. HapA, IL, MIP