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■ Abbreviation / Long Form : SHP2 / SH2 domain-containing phosphatase-2

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Total Number of Papers: 13
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Abbreviation:   SHP2  (>> Co-occurring Abbreviation)
Long Form:   SH2 domain-containing phosphatase-2
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No. Year Title Co-occurring Abbreviation
2021 Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to SHP2 Inhibition. ---
2021 The tyrosine phosphatase SHP2 promotes proliferation and oxaliplatin resistance of colon cancer cells through AKT and ERK. ---
2020 Molecular mechanism of SHP2 activation by PD-1 stimulation. ITIM, ITSM, PD-1, SH2
2020 SLAMF3-Mediated Signaling via ERK Pathway Activation Promotes Aggressive Phenotypic Behaviors in Multiple Myeloma. GRB2, MM, SLAMF3, sSLAMF3
2019 The multi-site docking protein Grb2-associated binder 1 (Gab1) enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner. ERK, Gab, Gab1, IL-6, MAPK, PI3K
2018 Dioscin overcome TKI resistance in EGFR-mutated lung adenocarcinoma cells via down-regulation of tyrosine phosphatase SHP2 expression. EGFR, ROS, TKIs
2016 Correlative analyses of the expression levels of PIAS3, p-SHP2, SOCS1 and SOCS3 with STAT3 activation in human astrocytomas. PIAS3, SOCS, STAT3
2015 EGF augments TGFbeta-induced epithelial-mesenchymal transition by promoting SHP2 binding to GAB1. EGF, EMT, TGF-beta
2015 EGFR-activated Src family kinases maintain GAB1-SHP2 complexes distal from EGFR. EGF, ERK, GAB1, SFKs, SH2
10  2013 Heterogeneous nuclear ribonucleoprotein Q is a novel substrate of SH2 domain-containing phosphatase-2. hnRNP Q, MALDI-TOF
11  2012 Model-driven experimental analysis of the function of SHP-2 in IL-6-induced Jak/STAT signaling. IL-6
12  2012 SH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in mice. BMMCs, ERK, KO
13  2009 SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc epsilon RI-induced activation of Fyn and Erk pathways leading to TNF alpha release from bone marrow-derived mast cells. BMMCs, KO