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■ Abbreviation / Long Form : TG / thapsigargin

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Total Number of Papers: 852
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Abbreviation:   TG  (>> Co-occurring Abbreviation)
Long Form:   thapsigargin
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No. Year Title Co-occurring Abbreviation
2021 A store-operated Ca2+-entry in Trypanosoma equiperdum: Physiological evidences of its presence. 2-APB, BHQ, T. brucei, T. equiperdum, T. evansi, TRP
2021 Altered estradiol-dependent cellular Ca2+ homeostasis and endoplasmic reticulum stress response in Premenstrual Dysphoric Disorder. ER, LCLs, PMDD, WGCNA
2021 Comparative Analysis of CREB3 and CREB3L2 Protein Expression in HEK293 Cells. BFA, ERAD, TM
2021 DYT-TOR1A subcellular proteomics reveals selective vulnerability of the nuclear proteome to cell stress. ER, MEFs
2021 ER stress and its PERK branch enhance TCR-induced activation in regulatory T cells. ATF4, ER, GRP78, IL-10, PKR, TCR, TGF-beta, UPR
2021 Gene Expression Profile of the Human Colorectal Carcinoma LoVo Cells Treated With Sporamin and Thapsigargin. CRC, CTL, DEGs, PPI, TF
2021 Harpagide exerts a neuroprotective effect by inhibiting endoplasmic reticulum stress via SERCA following oxygen-glucose deprivation/reoxygenation injury. CIRI, ERS, LSCM, OGD/R
2021 Hepatocyte Endoplasmic Reticulum Stress Inhibits Hepatitis B Virus Secretion and Delays Intracellular Hepatitis B Virus Clearance After Entecavir Treatment. ELISA, ER, ETV, GRP78, HBV, p-eIF2alpha, PBA, SA
2021 Identification of novel candidate biomarkers for pancreatic adenocarcinoma based on TCGA cohort. DEGs, PAAD
10  2021 Inhibition of Autophagy Prevents Panax Notoginseng Saponins (PNS) Protection on Cardiac Myocytes Against Endoplasmic Reticulum (ER) Stress-Induced Mitochondrial Injury, Ca2+ Homeostasis and Associated Apoptosis. ER, PNS, ROS
11  2021 Inonotsuoxide B regulates M1 to M2 macrophage polarization through sirtuin-1/endoplasmic reticulum stress axis. ARG, ERS, IB, IL, LPS, SIRT1, TNF
12  2021 LncRNA-Gm9795 promotes inflammation in non-alcoholic steatohepatitis via NF-[Formula: see text]B/JNK pathway by endoplasmic reticulum stress. ERS, LPS, MCD, NAFL, NASH, PA, TUDCA
13  2021 Molecular characterization and functional analysis of apoptosis-inducing factor (AIF) in palmitic acid-induced apoptosis in Ctenopharyngodon idellus kidney (CIK) cells. aa, AIF, CIK, ER, ORF, PA
14  2021 ORMDL3 overexpression facilitates FcεRI-mediated transcription of proinflammatory cytokines and thapsigargin-mediated PERK phosphorylation in RBL-2H3 cells. IL-4, IRE1, MAPK, MCP-1, ORMDL3, PERK, S1P, TNF-alpha, UPR
15  2021 Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress‑impaired endothelial cell angiogenic response: A critical role for cell survival. eNOS, ER, PTP, si
16  2021 Role of STIM2 and Orai proteins in regulating TRPC1 channel activity upon calcium store depletion. STIM, TRPC
17  2021 Rosuvastatin protects PC12 cells from hypoxia/reoxygenation-induced injury by inhibiting endoplasmic reticulum stress-induced apoptosis. CIRI, ERS, PERK
18  2021 Rutin alleviates cardiomyocyte injury induced by high glucose through inhibiting apoptosis and endoplasmic reticulum stress. CHOP, ERS
19  2021 Thapsigargin Is a Broad-Spectrum Inhibitor of Major Human Respiratory Viruses: Coronavirus, Respiratory Syncytial Virus and Influenza A Virus. ER, RSV
20  2021 The HSP GRP94 interacts with macrophage intracellular complement C3 and impacts M2 profile during ER stress. ER, TM
21  2021 Ufmylation regulates granulosa cell apoptosis via ER stress but not oxidative stress during goat follicular atresia. DDRGK1, GC, GCs, TM, Ufm1
22  2021 γ-Synuclein is Closely Involved in Autophagy that Protects Colon Cancer Cell from Endoplasmic Reticulum Stress. LC3
23  2020 1,25-hydroxyvitamin D3 decreases endoplasmic reticulum stress-induced inflammatory response in mammary epithelial cells. DDIT3, ER, MECs, NF-kappaB, PERK, sXBP1, TM, VDR
24  2020 Action of the insecticide cyfluthrin on Ca2+ signal transduction and cytotoxicity in human osteosarcoma cells. PKC, PLC
25  2020 Activating transcription factor 6 (ATF6) negatively regulates Polo-like kinase 4 expression via recruiting C/EBPbeta to the upstream-promoter during ER stress. ATF6, BFA, ER, PLK4, TM
26  2020 Calreticulin promotes EMT in pancreatic cancer via mediating Ca2+ dependent acute and chronic endoplasmic reticulum stress. CRT, EMT, ERS, PC
27  2020 Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components. ATG, ER, UPR
28  2020 Cistanches deserticola PhG-RE through Inhibiting ERS Apoptosis Mechanism to Protect Myocardial Cell Apoptosis from H2O2-Induced Endoplasmic Reticulum Stress. 4-PBA, ERS
29  2020 Cytosolic Ca2+ Modulates Golgi Structure Through PKCα-Mediated GRASP55 Phosphorylation. DTT, PKCalpha, TM, UPR
30  2020 Dexmedetomidine Attenuates Cellular Injury and Apoptosis in H9c2 Cardiomyocytes by Regulating p-38MAPK and Endoplasmic Reticulum Stress. CCK-8, DEX, ERS, IRI, LDH
31  2020 Endoplasmic Reticulum Stress Increases Multidrug-resistance Protein 2 Expression and Mitigates Acute Liver Injury. ER, MRP, NF-kappaB, PBA, PDTC
32  2020 Endoplasmic reticulum stress perpetuated toll-like receptor signalling-mediated inflammation in rheumatoid arthritis via X-box-binding protein-1. ER, RA, RASF, Th, TLRs, XBP1
33  2020 Endoplasmic reticulum stress, unfolded protein response and autophagy contribute to resistance to glucocorticoid treatment in human acute lymphoblastic leukaemia cells. ALL, CLQ, DEX, ER, GC, GRP, ROS, ROT, UPR
34  2020 ER stress induced by ER calcium depletion and UVB irradiation regulates tight junction barrier integrity in human keratinocytes. ER, NHEK, TJ, UPR, UVB
35  2020 Excitation-Contraction Coupling in the Goldfish (Carassius auratus) Intact Heart. APD50, APs, Ry
36  2020 Exploration of thioridazine-induced Ca2+ signaling and non-Ca2+-triggered cell death in HepG2 human hepatocellular carcinoma cells. PKC, PLC
37  2020 Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasis. ER, FliI-KD, RyRs, UPR
38  2020 Hepatitis B Virus DNA Polymerase Displays an Anti-Apoptotic Effect by Interacting with Elongation Factor-1 Alpha-2 in Hepatoma Cells. ER, HBV, pol
39  2020 In Vivo Anti-Inflammation Potential of Aster koraiensis Extract for Dry Eye Syndrome by the Protection of Ocular Surface. AKE, COX-1, COX-2, DES, ER
40  2020 Large Scale Conversion of Trilobolide into the Payload of Mipsagargin: 8-O-(12-Aminododecanoyl)-8-O-Debutanoylthapsigargin. Tb
41  2020 Liraglutide protects pancreatic beta cells from endoplasmic reticulum stress by upregulating MANF to promote autophagy turnover. C-cas-3, CCK-8, CQ, ER, GLU, HLD, LRG, MANF, PA, T2D
42  2020 Pharmacological Preconditioning Using Diazoxide Regulates Store-Operated Ca2 + Channels in Adult Rat Cardiomyocytes. 5-HD, Dzx, PPC, ROS
43  2020 Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response. NRVMs, TM
44  2020 Sigma-1 receptor is involved in diminished ovarian reserve possibly by influencing endoplasmic reticulum stress-mediated granulosa cells apoptosis. AFC, AMH, DHEA, DOR, ERS, FF, FSH, GCs, KGN, sigma 1 receptor
45  2020 TGF-β1 Activates Nasal Fibroblasts through the Induction of Endoplasmic Reticulum Stress. ECM, ER, PBA, ROS
46  2020 Thapsigargin at Non-Cytotoxic Levels Induces a Potent Host Antiviral Response that Blocks Influenza A Virus Replication. ER
47  2020 Thapsigargin promotes colorectal cancer cell migration through upregulation of lncRNA MALAT1. ATF4, CRC, ER, IRE1, lncRNA, MALAT1, PKR, XBP1
48  2020 The critical role of PPARα in the binary switch between life and death induced by endoplasmic reticulum stress. ER stress, TM
49  2020 Transcriptional regulation of the ER stress-inducible gene Sec16B in Neuro2a cells. BFA, ER, sXBP1, UPRE
50  2020 TRPP2 and STIM1 form a microdomain to regulate store-operated Ca2+ entry and blood vessel tone. 2-APB, ATP, cKO, siRNA, STIM1, VSMCs
51  2020 XBP1 negatively regulates CENPF expression via recruiting ATF6alpha to the promoter during ER stress. ATF6alpha, BFA, CENPF, ChIP, ER, TM, XBP1
52  2019 4-Phenylbutyric Acid Reduces Endoplasmic Reticulum Stress in Chondrocytes That Is Caused by Loss of the Protein Disulfide Isomerase ERp57. 4-PBA, ECM, ER, TEM, UPR
53  2019 Action of chlorzoxazone on Ca2+movement and viability in human oral cancer cells. PKC, PLC
54  2019 Activation of PERK in ET-1- and thrombin-induced pulmonary fibroblast differentiation: Inhibitory effects of curcumin. alpha-SMA, CCN2, Col I, CUR, ER, ET-1, IHC, JNK, PERK, PF, siRNA
55  2019 Adenylyl Cyclase Type 8 Overexpression Impairs Phosphorylation-Dependent Orai1 Inactivation and Promotes Migration in MDA-MB-231 Breast Cancer Cells. AC8, cAMP, FAK, OASF, PKA, PKC, siRNAs, STIM1, TNBC
56  2019 Allosteric modulation of the sarcoplasmic reticulum Ca2+ ATPase by thapsigargin via decoupling of functional motions. ---
57  2019 Angiotensin-converting enzyme 2 inhibits endoplasmic reticulum stress-associated pathway to preserve nonalcoholic fatty liver disease. ACE2, ER, NAFLD, PA, TC
58  2019 Calcium Imaging of Parvalbumin Neurons in the Dorsal Root Ganglia. DRG, GECI, PMCA, PV, RT, SERCA
59  2019 Calcium signalling in mammalian cell lines expressing wild type and mutant human α1-Antitrypsin. AAT, ER, FENIB
60  2019 Cellular secretion and cytotoxicity of transthyretin mutant proteins underlie late-onset amyloidosis and neurodegeneration. ATTR, ERQC, M-TTRs, TTR, UPR, WT
61  2019 Characterization of IRE1α in Neuro2a cells by pharmacological and CRISPR/Cas9 approaches. ER, sXBP1, TM
62  2019 Cigarette Smoke Extract Promotes Human Lung Myofibroblast Differentiation by the Induction of Endoplasmic Reticulum Stress. 4-PBA, alpha-SMA, ATF6, CSE, ER, GRP78, IPF, IRE1, XBP1
63  2019 Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells. ATF, EMT, ER stress, HLECs, TM, TUDCA
64  2019 Enteroids Derived From Inflammatory Bowel Disease Patients Display Dysregulated Endoplasmic Reticulum Stress Pathways, Leading to Differential Inflammatory Responses and Dendritic Cell Maturation. DCs, ER, IBD, IECs, moDCs, TLR
65  2019 ER stress activation impairs the expression of circadian clock and clock-controlled genes in NIH3T3 cells via an ATF4-dependent mechanism. ER, Luc, TM
66  2019 ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation. GBM, GSCs, UPR
67  2019 ER-stressed MSC displayed more effective immunomodulation in RA CD4+CXCR5+ICOS+ follicular helper-like T cells through higher PGE2 binding with EP2/EP4. ER, FACS, PBMCs, RA, UC-MSCs
68  2019 Follistatin Protects Against Glomerular Mesangial Cell Apoptosis and Oxidative Stress to Ameliorate Chronic Kidney Disease. CKD, ER, FST, MCs, ROS, TGF-beta
69  2019 Hsp60 and IL-8 axis promotes apoptosis resistance in cancer. Api, ELISA, HSP60, IL-8
70  2019 Hyperglycemia aggravates spinal cord injury through endoplasmic reticulum stress mediated neuronal apoptosis, gliosis and activation. BSCB, ER, HG, i.p, RSCNCs, SCI
71  2019 Icariin Inhibits Endoplasmic Reticulum Stress-induced Neuronal Apoptosis after Spinal Cord Injury through Modulating the PI3K/AKT Signaling Pathway. ER, ICA, SCI
72  2019 Liver parenchymal cells lacking Lipocalin 2 (LCN2) are prone to endoplasmic reticulum stress and unfolded protein response. APR, CHOP, ER, JNK, LCN2, LPS, NF-kappaB, ROS, TM, UPR, WT
73  2019 Panax Notoginseng Saponins Protect Cardiac Myocytes Against Endoplasmic Reticulum Stress and Associated Apoptosis Through Mediation of Intracellular Calcium Homeostasis. BiP, CHOP, ER, HPLC, MTT, PI, PNS, RyR2
74  2019 PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress. ER, TTR, UPR
75  2019 Pifithrin-Alpha Reduces Methamphetamine Neurotoxicity in Cultured Dopaminergic Neurons. ER, Gluc, GLuc-SERCaMP, METH, PFT-alpha
76  2019 Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress. CHOP, cIAP, ER, GRP78, IAP, NF-kappaB, PERK, Smac, TM, UPR, XBP1
77  2019 Thapsigargin induces apoptosis in adrenocortical carcinoma by activating endoplasmic reticulum stress and the JNK signaling pathway: an in vitro and in vivo study. ACC, ER, JNK, WB
78  2019 The PERK/Nrf2 pathway mediates endoplasmic reticulum stress-induced injury by upregulating endoplasmic reticulophagy in H9c2 cardiomyoblasts. ATF4, CRT, ER-phagy, ERS, LC3B, Nrf2, PERK, TM
79  2019 ZBTB7A, a miR-663a target gene, protects osteosarcoma from endoplasmic reticulum stress-induced apoptosis by suppressing LncRNA GAS5 expression. ER stress, TM
80  2018 A Flow Cytometric Study of ER Stress and Autophagy. CQ
81  2018 Anti-allergy activities of Kuji amber extract and kujigamberol. MEKA
82  2018 Calcium mobilization is responsible for Thapsigargin induced Epstein Barr virus lytic reactivation in invitro immortalized lymphoblstoid cell lines. EBV, LCLs, UPR
83  2018 CaMKII Potentiates Store-Operated Ca2+ Entry Through Enhancing STIM1 Aggregation and Interaction with Orai1. CaMKII, STIM1
84  2018 Changes of MODY signal pathway genes in the endoplasmic reticulum stress in INS-1-3 cells. DGE, ERS, GO, GSIS, MODY, MTT, PA, RT-PCR, TM
85  2018 Deficiency of protein-L-isoaspartate (D-aspartate) O-methyl-transferase expression under endoplasmic reticulum stress promotes epithelial mesenchymal transition in lung adenocarcinoma. D-aspartate, EMT, ER, HIF1alpha, si-PIMT
86  2018 Epigallocatechin Gallate Reduces Amyloid beta-Induced Neurotoxicity via Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis. AD, ER, TEM, TM
87  2018 ER stress mediated regulation of miR23a confer Hela cells better adaptability to utilize glycolytic pathway. 2-DG, UPR
88  2018 Exploration of Niflumic Acid’s Action on Ca⁺ Movement and Cell Viability in Human Osteosarcoma Cells. PKC, PLC, PMA, WST-1
89  2018 Fragment Molecular Orbital Study of the Interaction between Sarco/Endoplasmic Reticulum Ca2+-ATPase and its Inhibitor Thapsigargin toward Anti-Malarial Development. FMO
90  2018 Hepatitis B virus suppresses the secretion of insulin-like growth factor binding protein 1 to facilitate anti-apoptotic IGF-1 effects in HepG2 cells. CHB, HBV, HBx, HCC, IGF-1, IGFBP1, siRNA, STS
91  2018 High expression of active ATF6 aggravates endoplasmic reticulum stress‑induced vascular endothelial cell apoptosis through the mitochondrial apoptotic pathway. ATF6, Bax, CHOP, ER, VEC
92  2018 High pH-Sensitive Store-Operated Ca2+ Entry Mediated by Ca2+ Release-Activated Ca2+ Channels in Rat Odontoblasts. 2-MeSADP, CCh
93  2018 Interferon-τ regulates prostaglandin release in goat endometrial stromal cells via JAB1 - unfolded protein response pathway. ER, ESCs, IFN-tau, PGs, UPR
94  2018 Involvement of thapsigargin- and cyclopiazonic acid-sensitive pumps in the rescue of TMEM165-associated glycosylation defects by Mn2. KO, LAMP2, TMEM165
95  2018 Knockdown of RTN1-C attenuates traumatic neuronal injury through regulating intracellular Ca2+ homeostasis. ER, mGluR1, RTNs, STIM1, TBI, TNI
96  2018 Lysosomal exocytosis of ATP is coupled to P2Y2 receptor in marginal cells in the stria vascular in neonatal rats. 2-APB, ATP, ER, UTP
97  2018 Modulation of store-operated calcium entry and nascent adhesion by p21-activated kinase 1. PAKs, PDBu, SOCE, STIM1
98  2018 Orai1 downregulation impairs lymphocyte function in type 2 diabetes mellitus. IL-2, STIM1
99  2018 Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis. ---
100  2018 Piceatannol attenuates D-GalN/LPS-induced hepatoxicity in mice: Involvement of ER stress, inflammation and oxidative stress. FHF