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■ Abbreviation / Long Form : TLRs / Toll-like receptors

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Abbreviation:   TLRs  (>> Co-occurring Abbreviation)
Long Form:   Toll-like receptors
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No. Year Title Co-occurring Abbreviation
2021 10-hydroxy-2-decenoic acid a bio-immunomodulator in tissue engineering; generates tolerogenic dendritic cells by blocking the toll-like receptor4. 10-HDA, Alg-PEI, DCs, HEK-TLR4 cells
2021 A "Drug-Dependent" Immune System Can Compromise Protection against Infection: The Relationships between Psychostimulants and HIV. CNS
2021 A comprehensive systematic review of the therapeutic effects and mechanisms of action of quercetin in sepsis. PRISMA
2021 A domain-based vaccine construct against SARS-CoV-2, the causative agent of COVID-19 pandemic: development of self-amplifying mRNA and peptide vaccines. BCE, COVID-19, DPVC, MD, SAMV, SARS-CoV-2
2021 A new insight to characterize immunomodulation based on hepatopancreatic transcriptome and humoral immune factor analysis of the Cherax quadricarinatus infected with Aeromonas veronii. ALF, CAT, CHH, Cp, DEGs, LZM, PO, SOD, SPI
2021 A systematic literature review on the effects of exercise on human Toll-like receptor expression. ---
2021 A systematic review of toll-like receptors in endometriosis. NOS
2021 Aberrant Expression of TLR2, TLR7, TLR9, Splicing Variants of TLR4 and MYD88 in Chronic Lymphocytic Leukemia Patients. CLL, HVs
2021 Alteration of lipid metabolism, autophagy, apoptosis and immune response in the liver of common carp (Cyprinus carpio) after long-term exposure to bisphenol A. BPA, ERS, HDL-C, LDL-C, TC
10  2021 Altered tonsillar toll-like receptor (TLR)-1 and TLR-2 expression levels between periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA), and group A beta-hemolytic streptococcal (GAβHS) recurrent tonsillitis patients. GAbetaHS, IHC, LI, PFAPA, SE, TLR
11  2021 Association of single-nucleotide polymorphisms in tumour necrosis factor and human leukocyte antigens genes with type 1 diabetes. HLA, IL-1, IL-12B, IL-1R1, IL-2, IL1RN, SNPs, SSOP, T1D, TNF
12  2021 Attenuation of the Induction of TLRs 2 and 4 Mitigates Inflammation and Promotes Neurological Recovery After Focal Cerebral Ischemia. MCAO
13  2021 Cell Surface Expression of Endosomal Toll-Like Receptors-A Necessity or a Superfluous Duplication? ---
14  2021 Co-stimulatory effect of TLR2 and TLR4 stimulation on megakaryocytic development is mediated through PI3K/NF-ĸB and XBP-1 loop. ---
15  2021 Colonic Gene Expression and Fecal Microbiota in Diarrhea-predominant Irritable Bowel Syndrome: Increased Toll-like Receptor 4 but Minimal Inflammation and no Response to Mesalazine. IBS-D
16  2021 Computational discovery and ex-vivo validation study of novel antigenic vaccine candidates against tuberculosis. BCG, Mtb, MYD88, TB
17  2021 Critical roles of TLRs on the polarization of mesenchymal stem cells for cell therapy of viral infections: a notice for COVID-19 treatment. COVID-19, GVHD, MSCs
18  2021 Cross Kingdom Immunity: The Role of Immune Receptors and Downstream Signaling in Animal and Plant Cell Death. CLRs, DAMPs, NBD, NOD, PAMPs, PRRs, RLKs, RLPs
19  2021 Cross-Talk of Toll-Like Receptor 5 and Mu-Opioid Receptor Attenuates Chronic Constriction Injury-Induced Mechanical Hyperalgesia through a Protein Kinase C Alpha-Dependent Signaling. CCI, CGRP, IB4, MOR, pPKA RII, pPKCalpha, SP, TLR5
20  2021 Cryo-EM structures of Toll-like receptors in complex with UNC93B1. UNC93B1
21  2021 Cutaneous and ocular rosacea: Common and specific physiopathogenic mechanisms and study models. TRP, UVB, VEGF
22  2021 Cutaneous innate immune tolerance is mediated by epigenetic control of MAP2K3 by HDAC8/9. HDACs
23  2021 Cyclophilin D-dependent mitochondrial permeability transition amplifies inflammatory reprogramming in endotoxemia. CypD, IPA, MPT, mtDNA, NO, Nrf2, ROS, TNFR
24  2021 Dietary ω-3 fatty acids and their influence on inflammation via Toll-like receptor pathways. FAs, LCFAs, PRRs, PUFAs
25  2021 Distinct toll-like receptor signaling in the salamander response to tissue damage. DAMPs, PAMP
26  2021 Donor UNC-93 Homolog B1 genetic polymorphism predicts survival outcomes after unrelated bone marrow transplantation. BMT, SCT, SNP, UNC93B1
27  2021 Effects of Rifaximin on Luminal and Wall-Adhered Gut Commensal Microbiota in Mice. FISH, GCM, T-RFLP
28  2021 Effects of sodium butyrate supplementation on inflammation, gut microbiota, and short-chain fatty acids in Helicobacter pylori-infected mice. H. pylori, SB, SCFAs
29  2021 Elicited soybean extract attenuates proinflammatory cytokines expression by modulating TLR3/TLR4 activation in high-fat, high-fructose diet mice. DCs, ESE, HFFD, ND
30  2021 Eosinophilic Esophagitis and Microbiota: State of the Art. EoE, PRRs
31  2021 Evodiamine Enhanced the Anti-Inflammation Effect of Clindamycin in the BEAS-2B Cells Infected with H5N1 and Pneumoniae D39 Through CREB-C/EBPβ Signaling Pathway. IL, TNF
32  2021 Ex vivo mRNA expression of toll-like receptors during latent tuberculosis infection. mRNA, qRT-PCR
33  2021 Expatiating the molecular approaches of HMGB1 in diabetes mellitus: Highlighting signalling pathways via RAGE and TLRs. DM, HMGB1, RAGE
34  2021 Expression, signal transduction, and function analysis of TIRAP and TRIF in Nile tilapia (Oreochromis niloticus). AP-1, IFN-beta, NF-kappaB
35  2021 Flavonoids against the SARS-CoV-2 induced inflammatory storm. 3CLpro, ACE-2, BRD4, cytokine storm, DPP4, Nrf2
36  2021 Gene duplication and adaptive evolution of Toll-like receptor genes in birds. LRR
37  2021 Generation of an Isoform-level transcriptome Atlas of Macrophage Activation. IAMA, MDMs, PAMPs
38  2021 Genetic characterizations of Toll-like receptors in the brown rat and their associations with pathogen infections. HEV
39  2021 HMGB1: An overview of its roles in the pathogenesis of liver disease. HMGB1, RAGE
40  2021 Human cardiac fibroblasts produce pro-inflammatory cytokines upon TLRs and RLRs stimulation. polyIC, RIG
41  2021 Identification and expression analysis of sixteen Toll-like receptor genes, TLR1, TLR2a, TLR2b, TLR3, TLR5M, TLR5S, TLR7-9, TLR13a-c, TLR14, TLR21-23 in mandarin fish Siniperca chuatsi. LRRs, PAMP, PRRs, TIR
42  2021 Immunocompetent birds choose larger breeding colonies. MHC
43  2021 Immunoinformatic approach to design a multiepitope vaccine targeting non-mutational hotspot regions of structural and non-structural proteins of the SARS CoV2. HLA, MDS, SARS CoV2
44  2021 Immunosuppression and Neuroinflammation in Stroke Pathobiology. DAMPs
45  2021 Immunotherapies and immunomodulatory approaches in clinical trials - a mini review. SARS-CoV-2
46  2021 In silico analyses on the comparative sensing of SARS-CoV-2 mRNA by the intracellular TLRs of humans. COVID-19, SARS-CoV-2
47  2021 In-silico evidences on filarial cystatin as a putative ligand of human TLR4. ---
48  2021 Increased Expression of Toll-Like Receptor 4 in Skin of Dogs with Discoid Lupus Erythematous (DLE). DLE, PRR
49  2021 Inhibition of TLR7 and TLR9 Reduces Human Cholangiocarcinoma Cell Proliferation and Tumor Development. ICC
50  2021 Innate Immune Responses and Pulmonary Diseases. NLRs, PRRs, RLRs
51  2021 Innate Immune Sensing of Viruses and Its Consequences for the Central Nervous System. CDS, CLR, CNS, NLRs, PRRs, RIG-I
52  2021 Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis. Mtb, SNP, TB
53  2021 Interdependencies between Toll-like receptors in Leishmania infection. PAMPs
54  2021 Ionizing radiation and toll like receptors: A systematic review article. ---
55  2021 Landscape of Toll-like receptors expression in tumor microenvironment of Triple Negative Breast Cancer (TNBC): distinct roles of TLR4 and TLR8. DETs, IM, PTX, TME, TNBC
56  2021 Macrophage cytokine responses to commensal Gram-positive Lactobacillus salivarius strains are TLR2-independent and Myd88-dependent. MAMPs, PRRs
57  2021 Microbial Phagocytic Receptors and Their Potential Involvement in Cytokine Induction in Macrophages. PRRs, SRs
58  2021 MicroRNA Modulation of Host Immune Response and Inflammation Triggered by Helicobacter pylori. H. pylori, LPS, MiRNAs, NF-kB
59  2021 Molecular cloning and functional studies on magang goose toll-like receptor 5. LRRs, mgTLR5, RT-PCR, TIR, UTR
60  2021 Multifaceted roles of Toll-like receptors in acute kidney injury. AKI, IFNs, IL-1beta, NF-kappaB, PRRs
61  2021 N-palmitoyl-D-glucosamine, a Natural Monosaccharide-Based Glycolipid, Inhibits TLR4 and Prevents LPS-Induced Inflammation and Neuropathic Pain in Mice. PGA, PGA, SNI
62  2021 Naringenin suppresses Toll-like receptor 2-mediated inflammatory responses through inhibition of receptor clustering on lipid rafts. ---
63  2021 Neither microcystin, nor nodularin, nor cylindrospermopsin directly interact with human toll-like receptors. ---
64  2021 Novel Mechanisms of Ozone-Induced Pulmonary Inflammation and Resolution, and the Potential Protective Role of Scavenger Receptor BI. AMs, BALF, DAMPs, diHDoHE, HDHA, HPLC, MS/MS, OxPL, PRRs, SPMs, SR-BI, SR-BI KO, SRs, WT
65  2021 Oral Nanoparticles of SNX10-shRNA Plasmids Ameliorate Mouse Colitis. DSS, IBD, NPs, PLGA, SNX10, SRP
66  2021 Ostertagia ostertagi Mediates Early Host Immune Responses via Macrophage and Toll-Like Receptor Pathways. ESP, IL-10, PBMC, TNF-alpha
67  2021 Paracoccidioidomycosis Protective Immunity. NK
68  2021 Pathogenesis of Borrelia burgdorferi and Babesia microti in TLR4-Competent and TLR4-dysfunctional C3H Mice. BM, LPS, PAMPs
69  2021 Patterns of Toll-Like Receptor Expressions and Inflammatory Cytokine Levels and Their Implications in the Progress of Insulin Resistance and Diabetic Nephropathy in Type 2 Diabetic Patients. CRP, DNP, IFN-gamma, IL-6, INS, PB, T2DM, TLR2, TLR4, TNF-alpha
70  2021 Phosphatases in toll-like receptors signaling: the unfairly-forgotten. PRRs
71  2021 Platelets: 'multiple choice' effectors in the immune response and their implication in COVID-19 thromboinflammatory process. MHC
72  2021 Pre-treatment with Scopolamine Naturally Suppresses Japanese Encephalitis Viral Load in Embryonated Chick Through Regulation of Multiple Signaling Pathways. CAM, IFNs, JEV, NS5
73  2021 Presepsin: A Promising Biomarker for Sepsis. sCD14
74  2021 Protein phosphatases in TLR signaling. ---
75  2021 Pyruvate Kinase M2 Contributes to TLR-Mediated Inflammation and Autoimmunity by Promoting Pyk2 Activation. DCs, PKM2, Pyk2, SLE
76  2021 Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After α2-3-Linked Sialic Acid Ligand Binding. alpha2-3sia, DCs
77  2021 Radiofrequency Irradiation Attenuates High-Mobility Group Box 1 and Toll-like Receptor Activation in Ultraviolet B-Induced Skin Inflammation. HMGB1, PIH, RF, UVB
78  2021 Regulation of gene expression in chickens by heat stress. BDNF, CAT, HSP, nNOS, ROS, SOD
79  2021 Regulation of Toll-like receptor-mediated inflammatory response by microRNA-152-3p-mediated demethylation of MyD88 in systemic lupus erythematosus. DNMT1, miRNAs, MyD88, PBMCs, SLE
80  2021 Renin-angiotensin system and inflammation update. ACE2, Ang II, AT1R, AT2R, BET, NF-kappaB, PGC-1alpha, Ppp6C, RAS, SNRK, TRPA1
81  2021 Response to Anti-α4β7 Blockade in Patients With Ulcerative Colitis Is Associated With Distinct Mucosal Gene Expression Profiles at Baseline. UC
82  2021 RIPK2 as a New Therapeutic Target in Inflammatory Bowel Diseases. IBDs, NOD1, RIP2, RIPK2
83  2021 RNA sensors as a mechanism of innate immune evasion among SARS-CoV2, HIV and Nipah viruses. IFN, NOD, PRR, RIG-I
84  2021 Role of genetic variants of Vitamin D receptor, Toll-like receptor 2 and Toll-like receptor 4 in extrapulmonary tuberculosis. EPTB, Mtb, TB, VDR
85  2021 Role of pattern recognition receptors and the microbiota in neurological disorders. NLRs, PRRs
86  2021 Role of TLR2 and TLR4 Signaling in Parkinson's Disease: An Insight into Associated Therapeutic Potential. PD
87  2021 Sequence and Structural Characterization of Toll-Like Receptor 6 from Human and Related Species. LRR
88  2021 Sox4 represses host innate immunity to facilitate pathogen infection by hijacking the TLR signaling networks. IFNs, ISG, MyD88, NF-kappaB, SOX4
89  2021 Sphingosine-1-Phosphate Contributes to TLR9-Induced TNF-α Release in Lung Tumor Cells. CpG, S1P
90  2021 Structural and Evolutionary Adaptation of NOD-Like Receptors in Birds. DAMPs, NLRs, PAMPs
91  2021 Structural and functional understanding of the toll-like receptors. ---
92  2021 Structurally diverse genes encode TLR13 in Nile tilapia: The two receptors can recognize Streptococcus 23S RNA and conduct signal transduction through MyD88. Co-IP, dpf, IFN-beta, IL, LRR
93  2021 Structure based design and synthesis of novel Toll-like Receptor 2 (TLR 2) lipid antagonists. DAMPs, PAMPs, TLR2
94  2021 Subvisible Particles in Solutions of Remicade in Intravenous Saline Activate Immune System Pathways in In Vitro Human Cell Systems. DCs, PBMC
95  2021 Sulforaphane suppresses lipopolysaccharide- and Pam3CysSerLys4-mediated inflammation in chronic obstructive pulmonary disease via toll-like receptors. COPD, IL-6, LPS, MDMs, MyD88, SFN, TNF-alpha
96  2021 Synergistic inflammatory signaling by cGAS may be involved in the development of atherosclerosis. cGAS, dsDNA, IFNs, IRF, RT-qPCR, STAT
97  2021 Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19. COVID-19, NETs
98  2021 Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19. COVID-19, NETs
99  2021 Targeting Innate Immunity in Cancer Therapy. CTLA-4, ICI, NLRs, PD-L1, PRRs, RIG-I, TME
100  2021 Targeting Toll-Like Receptors in Sepsis: From Bench to Clinical Trials. ---