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■ Abbreviation / Long Form : UDPGA / UDP-glucuronic acid

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Total Number of Papers: 62
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Abbreviation:   UDPGA  (>> Co-occurring Abbreviation)
Long Form:   UDP-glucuronic acid
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No. Year Title Co-occurring Abbreviation
2022 Integrate thermostabilized fusion protein apocytochrome b 562 RIL and N-glycosylation mutations: A novel approach to heterologous expression of human UDP-glucuronosyltransferase (UGT) 2B7. SPR, TEM, UGT
2021 Development of a microplate method for the determination of hepatic UDP-glucuronosyltransferase activity in rainbow trout (Oncorhynchus mykiss) and Nile tilapia (Oreochromis niloticus). beta-NF, PNP, UDP
2020 SLC35B1 significantly contributes to the uptake of UDPGA into the endoplasmic reticulum for glucuronidation catalyzed by UDP-glucuronosyltransferases. 4-MU, ER, UGT
2019 Efforts in redesigning the antileukemic drug 6-thiopurine: decreasing toxic side effects while maintaining efficacy. 6TP, UDPGDH
2019 Enzymatic analysis of glucuronidation of synthetic cannabinoid 1-naphthyl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate (FDU-PB-22). HLMs, SCBs, UGTs
2018 Enhanced activity of Withania somnifera family-1 glycosyltransferase (UGT73A16) via mutagenesis. ---
2018 Inhibition of UDP-glucose dehydrogenase by 6-thiopurine and its oxidative metabolites: Possible mechanism for its interaction within the bilirubin excretion pathway and 6TP associated liver toxicity. 6TP, UDPGDH
2014 Characterization of the zebrafish Ugt repertoire reveals a new class of drug-metabolizing UDP glucuronosyltransferases. UGT
2010 Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity: a comparative study in humans and rodents including chimeric mice carrying human liver. UGT
10  2010 Effects of Andrographis paniculata and Orthosiphon stamineus extracts on the glucuronidation of 4-methylumbelliferone in human UGT isoforms. 4-MU
11  2010 Metabolism of ebracteolata compound B studied in vitro with human liver microsomes, HepG2 cells, and recombinant human enzymes. ECB, UGT
12  2009 Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins. CB, DILI
13  2009 In vitro metabolism of haloperidol and sila-haloperidol: new metabolic pathways resulting from carbon/silicon exchange. sila-haloperidol
14  2009 Local differentiation of sugar donor specificity of flavonoid glycosyltransferase in Lamiales. F7GAT, UGTs
15  2008 Organochlorines inhibit acetaminophen glucuronidation by redirecting UDP-glucuronic acid towards the D-glucuronate pathway. BCPS
16  2007 Carboxyl-glucuronidation of mitiglinide by human UDP-glucuronosyltransferases. MGN, UGT
17  2007 The human UDP-glucuronosyltransferase: identification of key residues within the nucleotide-sugar binding site. UGTs
18  2006 Galactosamine prevents ethinylestradiol-induced cholestasis. EE
19  2006 Identification of human UDP-glucuronosyltransferase responsible for the glucuronidation of niflumic acid in human liver. HLMs, UDP
20  2006 Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family. NST, UGT
21  2006 Which hydroxy? Evidence for species differences in the regioselectivity of glucuronidation in rat, dog, and human in vitro systems and dog in vivo. ---
22  2005 Kinetic characterization of the 1A subfamily of recombinant human UDP-glucuronosyltransferases. cat, UGTs
23  2004 Formation and protein binding of the acyl glucuronide of a leukotriene B4 antagonist (SB-209247): relation to species differences in hepatotoxicity. ---
24  2004 Formation of a structurally novel, serial diglucuronide of 4-hydroxybiphenyl by further glucuronidation of a monoglucuronide in dog liver microsomes. HPLC, MS/MS, NMR, UGT
25  2004 Glucuronidation of haloperidol by rat liver microsomes: involvement of family 2 UDP-glucuronosyltransferases. HAL, HALG, RLM, UGT
26  2004 Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). Th, UGT
27  2004 Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4. TAM, UGT
28  2003 Evidence that unsaturated fatty acids are potent inhibitors of renal UDP-glucuronosyltransferases (UGT): kinetic studies using human kidney cortical microsomes and recombinant UGT1A9 and UGT2B7. 4-MU, AA, FA, HKCM, LA, UGT
29  2002 Acyl glucuronidation and glucosidation of a new and selective endothelin ET(A) receptor antagonist in human liver microsomes. UDPG
30  2002 Isolation and characterization of the monkey UGT2B30 gene that encodes a uridine diphosphate-glucuronosyltransferase enzyme active on mineralocorticoid, glucocorticoid, androgen and oestrogen hormones. HK293, UGT
31  2002 Significance of altered bilirubin subfractions in bile following hepatectomy. BDG, LPS, TAN, UDPGT
32  2000 Panipenum, a carbapenem antibiotic, increases the level of hepatic UDP-glucuronic acid in rats. PAPM, VPA
33  1999 In vitro assessment of paracetamol-induced toxicity in the rat Reuber hepatoma H4IIEC3/G(-) cell line competent of xenobiotics metabolism. UGT
34  1997 Effects of silymarin on UDP-glucuronic acid and glucuronidation activity in the rat isolated hepatocytes and liver in relation to D-galactosamine toxicity. 3-OH-BP, GalN, UDPGDH, UGT
35  1997 Structure and function of uridine diphosphate glucuronosyltransferases. ER, UDP
36  1996 Formation of beta-glucuronides and of beta-galacturonides of various retinoids catalyzed by induced and noninduced microsomal UDP-glucuronosyltransferases of rat liver. RA, RAG, ROG, ROL, UGT
37  1996 New concepts in bilirubin and jaundice: report of the Third International Bilirubin Workshop, April 6-8, 1995, Trieste, Italy. ATP, HO, HSA, NMR, UCB
38  1995 Kinetic analysis of UDP-glucuronosyltransferase in bilirubin conjugation by encapsulated hepatocytes for transplantation into Gunn rats. UDPGT
39  1994 Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation. UGT
40  1994 Mechanism of covalent adduct formation of diclofenac to rat hepatic microsomal proteins. Retention of the glucuronic acid moiety in the adduct. ---
41  1994 Mechanistic studies of uridine diphosphate glucuronosyltransferase. UDPGT
42  1993 Impairment of UDP-glucose dehydrogenase and glucuronidation activities in liver and small intestine of rat and guinea pig in vitro by piperine. UDPGDH, UGT
43  1992 An improved assay method for UDP-glucuronyltransferase activity towards 5-hydroxytryptamine and the characteristic properties of the enzyme. 5-HT, GT
44  1992 Effects of microsomal enzyme inducers upon UDP-glucuronic acid concentration and UDP-glucuronosyltransferase activity in the rat intestine and liver. 3-MC, AA, BaP, BHA, HA, NA, PB, PCN, TCDD, TSO, UDPG, UDPGT
45  1992 Mechanism of cadmium-decreased glucuronidation in the rat. UDPG, UDPGDH
46  1991 Circadian variation of hepatic UDP-glucuronic acid and the glucuronidation of xenobiotics in mice. ---
47  1990 Effect of UDP-glucuronic acid depletion by salicylamide on biliary bilirubin excretion in the rat. BMG
48  1990 Glucuronidation of codeine and morphine in human liver and kidney microsomes: effect of inhibitors. C6G, GT
49  1989 32P-postlabelling analysis of DNA adducts of benzo[a]pyrene formed in complex metabolic activation systems in vitro. BP, TCPO
50  1989 Impaired hepatic elimination of paranitrophenol and its metabolites in the rat following chronic ethanol pretreatment. PNP
51  1988 6-Amino-chrysene, a potent inhibitor of transferase activity in single living RTG2 cells. 6-AC, AHH, BP, GT
52  1988 Effect of galactosamine-induced hepatic UDP-glucuronic acid depletion on acetaminophen elimination in rats. Dispositional differences between hepatically and extrahepatically formed glucuronides of acetaminophen and other chemicals. AA, Gal
53  1988 Glucuronidation of 7-hydroxycoumarin in periportal and pericentral regions of the lobule in livers from untreated and 3-methylcholanthrene-treated rats. ---
54  1988 Glucuronidation of morphine in human kidney microsomes. GT
55  1988 Mechanism of decreased acetaminophen glucuronidation in the fasted rat. ---
56  1988 The effect of age on the glucuronidation and toxicity of 4,4'-thiobis(6-t-butyl-m-cresol). TBBC
57  1986 The inducibility and ontogeny of rat liver UDP-glucuronyltransferase toward furosemide. 3-MC, FG, PB, PCN, UDPGT
58  1983 Optimal assay conditions for liver UDP-glucuronosyltransferase from the rainbow trout, Salmo gairdneri. PNP
59  1983 Separation, purification and characterization of three isoenzymes of UDP-glucuronyltransferase from rat liver microsomes. UDPGT
60  1982 Induction of UDP-glucuronosyltransferase activities in Gunn, heterozygous, and Wistar rat livers by pregnenolone-16 alpha-carbonitrile. 3-MC, PB, PCN, UDPGT
61  1981 Ethanol and psychotropic drug interaction during pregnancy and lactation. UDPG
62  1975 Glucuronidation in cultures of human skin epithelial cells. FB