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[Related PubMed/MEDLINE]
Total Number of Papers: 157
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| Abbreviation |
: 25-HC |
| Long Form |
: 25-hydroxycholesterol |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2022 |
25-Hydroxycholesterol-Induced Oxiapoptophagy in L929 Mouse Fibroblast Cell Line. |
--- |
| 2 |
2022 |
Assessment of FDA-Approved Drugs as a Therapeutic Approach for Niemann-Pick Disease Type C1 Using Patient-Specific iPSC-Based Model Systems. |
iPSCs, NPC1, PCs |
| 3 |
2022 |
Ch25h and 25-HC prevent liver steatosis through regulation of cholesterol metabolism and inflammation. |
CH25H, HFD, LXRalpha, NAFLD, SREBP-2 |
| 4 |
2022 |
Coxiella burnetii Sterol-Modifying Protein Stmp1 Regulates Cholesterol in the Intracellular Niche. |
CCV |
| 5 |
2022 |
Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced Steatosis. |
CH25H, CYP7A1, HFD, WT |
| 6 |
2022 |
Senolysis induced by 25-hydroxycholesterol targets CRYAB in multiple cell types. |
--- |
| 7 |
2022 |
Transcription of cytochrome P450 46A1 in NIH3T3 cells is negatively regulated by FBS. |
24S-HC, 27HC, CH25H, Cyp46A1, IGF-II |
| 8 |
2021 |
25-Hydroxycholesterol Inhibits Kaposi's Sarcoma Herpesvirus and Epstein-Barr Virus Infections and Activates Inflammatory Cytokine Responses. |
CH25H, IFN, IL-8, ISGs, LANA, miRNAs, PBMCs, RNA-Seq, SARS-CoV-2 |
| 9 |
2021 |
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy. |
3-MA, I/R |
| 10 |
2021 |
25-Hydroxycholesterol protecting from cerebral ischemia-reperfusion injury through the inhibition of STING activity. |
MCAO, STING |
| 11 |
2021 |
25-Hydroxycholesterol suppress IFN-γ-induced inflammation in microglia by disrupting lipid raft formation and caveolin-mediated signaling endosomes. |
BBB, IFN-gamma |
| 12 |
2021 |
25-Hydroxycholesterol-Conjugated EK1 Peptide with Potent and Broad-Spectrum Inhibitory Activity against SARS-CoV-2, Its Variants of Concern, and Other Human Coronaviruses. |
CH25H, CoV, VOCs |
| 13 |
2021 |
A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol. |
CH25H, KO, LPS, LTP |
| 14 |
2021 |
A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols. |
SREBP, TM |
| 15 |
2021 |
Antiviral Actions of 25-Hydroxycholesterol in Fish Vary With the Virus-Host Combination. |
CH25H, CyHV-3, IPNV, Para, SVCV, VHSV |
| 16 |
2021 |
Cholesterol 25-hydroxylase inhibits Senecavirus A replication by enzyme activity-dependent and independent mechanisms. |
CH25H-M, SVA |
| 17 |
2021 |
Cholesterol 25-hydroxylase suppresses porcine deltacoronavirus infection by inhibiting viral entry. |
CH25H, PDCoV |
| 18 |
2021 |
Cholesterol-25-Hydroxylase Suppresses Seneca Valley Virus Infection via Producing 25-Hydroxycholesterol to Block Adsorption Procedure. |
CH25H, SVV |
| 19 |
2021 |
Immune-related oxysterol modulates neuromuscular transmission via non-genomic liver X receptor-dependent mechanism. |
LXRs, ROS, SVs |
| 20 |
2021 |
Insulin-induced genes INSIG1 and INSIG2 mediate oxysterol-dependent activation of the PERK-eIF2α-ATF4 axis. |
ATF4, INSIGs |
| 21 |
2021 |
Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm. |
ARDS, COVID-19, DDAB, SARS-CoV-2 |
| 22 |
2021 |
Modulation of Antiviral Immunity and Therapeutic Efficacy by 25-Hydroxycholesterol in Chronically SIV-Infected, ART-Treated Rhesus Macaques. |
ART, CH25H, RMs |
| 23 |
2021 |
Testicular 25-hydroxycholesterol: An alternate substrate for steroidogenesis in reptiles. |
FSH, LC, TMCM |
| 24 |
2021 |
The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation. |
CH25H, IgA, PC |
| 25 |
2021 |
Tumor Necrosis Factor-alpha utilizes MAPK/NFkappaB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway. |
ATF2, C25H, FAK, TNF |
| 26 |
2020 |
25-Hydroxycholesterol amplifies microglial IL-1beta production in an apoE isoform-dependent manner. |
AD, APOE4, CH25H, DAM, LPS, TLR4 |
| 27 |
2020 |
25-Hydroxycholesterol Induces Death Receptor-mediated Extrinsic and Mitochondria-dependent Intrinsic Apoptosis in Head and Neck Squamous Cell Carcinoma Cells. |
--- |
| 28 |
2020 |
25-Hydroxycholesterol promotes vascular calcification via activation of endoplasmic reticulum stress. |
CVC, ERS, VSMCs |
| 29 |
2020 |
25-Hydroxycholesterol protects against myocardial ischemia-reperfusion injury via inhibiting PARP activity. |
IR |
| 30 |
2020 |
Aggregation of 25-hydroxycholesterol in a complex biomembrane. Differences with cholesterol. |
--- |
| 31 |
2020 |
Cholesterol 25-hydroxylase (CH25H) as a promoter of adipose tissue inflammation in obesity and diabetes. |
ATMs, BMDMs, CH25H, DIO, HFD, IR, VAT |
| 32 |
2020 |
Cholesterol 25-hydroxylase inhibits encephalomyocarditis virus replication through enzyme activity-dependent and independent mechanisms. |
EMCV, ISG |
| 33 |
2020 |
Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol. |
ACAT, CH25H, COVID-19, ISGs, MERS-CoV |
| 34 |
2020 |
Cholesterol 25-hydroxylase promotes efferocytosis and resolution of lung inflammation. |
AM, CH25H, LXR |
| 35 |
2020 |
Cholesterol 25-hydroxylase protects against experimental colitis in mice by modulating epithelial gut barrier function. |
CH25H, DSS |
| 36 |
2020 |
Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion. |
CH25H, IFN, VSV |
| 37 |
2020 |
Cholesterol metabolism regulation mediated by SREBP-2, LXRalpha and miR-33a in rainbow trout (Oncorhynchus mykiss) both in vivo and in vitro. |
LXRs, SREBPs |
| 38 |
2020 |
EHMT2 Inhibition Induces Cell Death in Human Non-Small Cell Lung Cancer by Altering the Cholesterol Biosynthesis Pathway. |
EHMT2, NSCLC |
| 39 |
2020 |
Esterification of 4beta-hydroxycholesterol and other oxysterols in human plasma occurs independently of LCAT. |
24S-HC, 27HC, 4betaHC, 5,6alpha-EC, 5,6betaEC, 7-KC, 7alphaHC, CT, FED, FLD |
| 40 |
2020 |
High Glucose Induces Lipid Accumulation via 25-Hydroxycholesterol DNA-CpG Methylation. |
DNMT1, HG |
| 41 |
2020 |
Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins. |
CDCs, IFN |
| 42 |
2020 |
Multifaceted Functions of CH25H and 25HC to Modulate the Lipid Metabolism, Immune Responses, and Broadly Antiviral Activities. |
CH25H, EBOV, HIV, NiV, RVFV, ZIKV |
| 43 |
2020 |
Multiple Roles of 25-Hydroxycholesterol in Lipid Metabolism, Antivirus Process, Inflammatory Response, and Cell Survival. |
--- |
| 44 |
2020 |
Oxysterol 25-hydroxycholesterol as a metabolic pathophysiological factors of osteoarthritis induces apoptosis in primary rat chondrocytes. |
CH25H |
| 45 |
2020 |
Oxysterol 25-hydroxycholesterol as a metabolic pathophysiological factors of osteoarthritis induces apoptosis in primary rat chondrocytes. |
CH25H |
| 46 |
2020 |
Oxysterols provide innate immunity to bacterial infection by mobilizing cell surface accessible cholesterol. |
ACAT, CH25H |
| 47 |
2020 |
Spermine synthesis inhibitor blocks 25-hydroxycholesterol-induced- apoptosis via SREBP2 upregulation in DLD-1 cell spheroids. |
--- |
| 48 |
2020 |
Sterol metabolism modulates susceptibility to HIV-1 Infection. |
HESN, ISG, MDMs, PBMCs, pDCs |
| 49 |
2019 |
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4. |
FABP4, HCC, TLR4 |
| 50 |
2019 |
Cholesterol 25-Hydroxylase inhibits bovine parainfluenza virus type 3 replication through enzyme activity-dependent and -independent ways. |
BPIV3, gRNA, ISG |
| 51 |
2019 |
Cholesterol 25-hydroxylase negatively regulates porcine intestinal coronavirus replication by the production of 25-hydroxycholesterol. |
CH25H, CH25H-M, PEDV, TGEV |
| 52 |
2019 |
Cholesterol 25-hydroxylase suppresses rabies virus infection by inhibiting viral entry. |
CH25H, ISG, RABV |
| 53 |
2019 |
Cholesterol-25-hydroxylase Is a Chicken ISG That Restricts ALV-J Infection by Producing 25-hydroxycholesterol. |
ALV-J, chCH25H, hpi, IFN-alpha, ISGs, PBMC |
| 54 |
2019 |
Exogenous Addition of 25-Hydroxycholesterol Reduces Level of Very Long-Chain Fatty Acids in X-Linked Adrenoleukodystrophy. |
CH25H, iPSCs, LXR, VLCFAs, X-ALD |
| 55 |
2019 |
Fish Cholesterol 25-Hydroxylase Inhibits Virus Replication via Regulating Interferon Immune Response or Affecting Virus Entry. |
CH25H, FA, IFN, LPS, RGNNV, SGIV |
| 56 |
2019 |
Integrin activation by the lipid molecule 25-hydroxycholesterol induces a proinflammatory response. |
FAK |
| 57 |
2019 |
Lipid Exchange Factors at Membrane Contact Sites in African Swine Fever Virus Infection. |
ACBD3, ASF, ASFV, ITZ, MCSs, ORP4, OSBP, PI4Kbeta, VFs |
| 58 |
2019 |
Macrophage Migration Inhibitory Factor Promotes Chemotaxis of Astrocytes through Regulation of Cholesterol 25-Hydroxylase Following Rat Spinal Cord Injury. |
CH25H, CNS |
| 59 |
2019 |
Mining for Oxysterols in Cyp7b1-/- Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5. |
24S,25-EC, 26HC, INSIG, LC-MS, MSn, SPG5, SREBP-2, WT |
| 60 |
2019 |
Mitochondrial oxysterol biosynthetic pathway gives evidence for CYP7B1 as controller of regulatory oxysterols. |
24HC, 26HC, 26HC, CDCA |
| 61 |
2019 |
Modulation of cell proteome by 25-hydroxycholesterol and 27-hydroxycholesterol: A link between cholesterol metabolism and antiviral defense. |
27HC, JAM-A |
| 62 |
2019 |
Oxysterols and apolipoproteins in multiple sclerosis: a 5 year follow-up study. |
27HC, 7-KC, 7alphaHC, HCs, MS, PMS, RRMS, SP-MS |
| 63 |
2019 |
Porcine Reproductive and Respiratory Syndrome Virus E Protein Degrades Porcine Cholesterol 25-Hydroxylase via the Ubiquitin-Proteasome Pathway. |
CH25H, pCH25H, PRRSV |
| 64 |
2019 |
The Oxysterol 25-Hydroxycholesterol Inhibits Replication of Murine Norovirus. |
22-S-HC, HSV-1, MNV |
| 65 |
2019 |
The Oxysterol Synthesising Enzyme CH25H Contributes to the Development of Intestinal Fibrosis. |
CD, CH25H |
| 66 |
2018 |
25-Hydroxycholesterol activates the expression of cholesterol 25-hydroxylase in an LXR-dependent mechanism. |
CH25H, LXR |
| 67 |
2018 |
25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes. |
27HC, HRV, OSBP, VAP-A |
| 68 |
2018 |
25-Hydroxycholesterol Production by the Cholesterol-25-Hydroxylase Interferon-Stimulated Gene Restricts Mammalian Reovirus Infection. |
CH25H, ISGs, ISVPs |
| 69 |
2018 |
25-Hydroxycholesterol protects against acute lung injury via targeting MD-2. |
ALI, LPS, MD-2 |
| 70 |
2018 |
25-hydroxycholesterol reduces inflammation, viral load and cell death in ZIKV-infected U-87 MG glial cell line. |
ZIKV |
| 71 |
2018 |
Activation of liver X receptor plays a central role in antiviral actions of 25-hydroxycholesterol. |
25HC3S, CH25H, HSV-1, IFN, LXR |
| 72 |
2018 |
Antiviral effect of 25-hydroxycholesterol against porcine reproductive and respiratory syndrome virus in vitro. |
PRRSV |
| 73 |
2018 |
Effect of 25-hydroxycholesterol in viral membrane fusion: Insights on HIV inhibition. |
HIV-FP |
| 74 |
2018 |
Evaluation of 4beta-Hydroxycholesterol and 25-Hydroxycholesterol as Endogenous Biomarkers of CYP3A4: Study with CYP3A-Humanized Mice. |
4betaHC, CYP3A |
| 75 |
2018 |
Regulating Innate and Adaptive Immunity for Controlling SIV Infection by 25-Hydroxycholesterol. |
CH25H, LPS |
| 76 |
2018 |
Theonellamide A, a marine-sponge-derived bicyclic peptide, binds to cholesterol in aqueous DMSO: Solution NMR-based analysis of peptide-sterol interactions using hydroxylated sterol. |
Chol, DMSO, TNM-A, TNMs |
| 77 |
2017 |
25-Hydroxycholesterol and inflammation in Lovastatin-deregulated mevalonate pathway. |
MK, MKD, MVK |
| 78 |
2017 |
25-Hydroxycholesterol promotes migration and invasion of lung adenocarcinoma cells. |
ADC, IL-1beta |
| 79 |
2017 |
25-hydroxycholesterol promotes RANKL-induced osteoclastogenesis through coordinating NFATc1 and Sp1 complex in the transcription of miR-139-5p. |
BMMs, M-CSF, NFATc1, RANKL |
| 80 |
2017 |
25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model. |
CH25H, ZIKV |
| 81 |
2017 |
Biophysical Properties and Antiviral Activities of Measles Fusion Protein Derived Peptide Conjugated with 25-Hydroxycholesterol. |
MV |
| 82 |
2017 |
Cholesterol 25-hydroxylase acts as a host restriction factor on pseudorabies virus replication. |
CH25H, PRV |
| 83 |
2017 |
Cholesterol 25-Hydroxylase Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication through Enzyme Activity-Dependent and -Independent Mechanisms. |
CH25H, CH25H-M, nsp1alpha, PRRSV, siRNA |
| 84 |
2017 |
Cholesterol 25-hydroxylase is an interferon-inducible factor that protects against porcine reproductive and respiratory syndrome virus infection. |
CH25H, PRRSV |
| 85 |
2017 |
Interferon-independent antiviral activity of 25-hydroxycholesterol in a teleost fish. |
CH25H, IFNs, LPS, SVCV |
| 86 |
2017 |
Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation. |
AIM2, CH25H, IL-1beta, LPS |
| 87 |
2017 |
Purification and identification of 25-hydroxycholesterol in a reptile: Seasonal variation and hormonal regulation. |
FSH, HPLC, MS, TMCM |
| 88 |
2017 |
Viral MicroRNAs Repress the Cholesterol Pathway, and 25-Hydroxycholesterol Inhibits Infection. |
CH25H, CoA, HHV-8, HUVECs, KSHV, miRNAs, siRNAs |
| 89 |
2016 |
25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome. |
CCALD, CH25H, LXR, ROS, VLCFA, X-ALD |
| 90 |
2016 |
25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation. |
CH25H, ISG, LASV, siRNA |
| 91 |
2016 |
Characterization of Glycoprotein-Mediated Entry of Severe Fever with Thrombocytopenia Syndrome Virus. |
DC-SIGN, DC-SIGNR, GPs, SFTS, SFTSV, SFTSV, VSV |
| 92 |
2016 |
Immune oxysterols: Role in mycobacterial infection and inflammation. |
--- |
| 93 |
2016 |
Mass spectrometry profiling of oxysterols in human sperm identifies 25-hydroxycholesterol as a marker of sperm function. |
--- |
| 94 |
2016 |
RORalpha and 25-Hydroxycholesterol Crosstalk Regulates Lipid Droplet Homeostasis in Macrophages. |
CH25H, LD |
| 95 |
2015 |
A novel intrinsically fluorescent probe for study of uptake and trafficking of 25-hydroxycholesterol. |
25-HCTL |
| 96 |
2015 |
Armand-Frappier Outstanding Student Award--The emerging role of 25-hydroxycholesterol in innate immunity. |
--- |
| 97 |
2015 |
Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection. |
CH25H, HCV |
| 98 |
2015 |
Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation. |
CH25H, hCH25H, HCV |
| 99 |
2015 |
Lysophosphatidylcholine promotes SREBP-2 activation via rapid cholesterol efflux and SREBP-2-independent cytokine release in human endothelial cells. |
IL-6, LPC, SREBP-2 |
| 100 |
2015 |
MicroRNAs regulate the immunometabolic response to viral infection in the liver. |
HCV, miRNAs |
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