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Abbreviation : 9cRA
Long Form : 9-cis retinoic acid
No. Year Title Co-occurring Abbreviation
2022 Human Plasma Metabolomics Identify 9-cis-retinoic Acid and Dehydrophytosphingosine Levels as Novel biomarkers for Early Ventricular Fibrillation after ST-elevated Myocardial Infarction. AUC, ROC, STEMI, VF
2022 Potencies of organotin compounds in scallop RXRa responsive activity with a GAL4-based reconstituted yeast assay in vitro. CfRXRa, OTCs, RXR, RXRE
2022 Use of GAL4 factor-based yeast assay to quantify the effects of xenobiotics on RXR homodimer and RXR/PPAR heterodimer in scallop Chlamys farreri. OTCs, PPAR, RPalpha, RPgamma, RR, RXR
2021 Human prostate epithelial cells and prostate-derived stem cells malignantly transformed in vitro with sodium arsenite show impaired Toll like receptor -3 (TLR3)-associated anti-tumor pathway. As-CSCs, CAsE-PE, CSCs, iAs, PCa, PIC, RARbeta, SCs, TLR3
2020 9-cis Retinoic acid and 1.25-dihydroxyvitamin D3 drive differentiation into IgA+ secreting plasmablasts in human naive B cells. GLT
2020 Vitamin A controls the allergic response through T follicular helper cell as well as plasmablast differentiation. ---
2019 Role of RXRbeta in platelet function and arterial thrombosis. MA, MK, RXR, WT
2018 Characterization and comparison of transcriptional activities of the retinoid X receptors by various organotin compounds in three prosobranch gastropods; Thais clavigera, Nucella lapillus and Babylonia japonica. RXRE, TBT, TCHT, TeBT, TPhT, TPrT
2018 Differentiation-Induced Remodelling of Store-Operated Calcium Entry Is Independent of Neuronal or Glial Phenotype but Modulated by Cellular Context. ---
10  2018 Human Plasma Metabolomics Implicates Modified 9-cis-Retinoic Acid in the Phenotype of Left Main Artery Lesions in Acute ST-Segment Elevated Myocardial Infarction. AUC, LMCAD, STEMI
11  2017 9-cis retinoic acid induces neurorepair in stroke brain. dMCAO, SVZ
12  2017 9-cis retinoic acid modulates the type I allergic immune response. OVA
13  2017 Dysregulatory effects of retinoic acid isomers in late zebrafish embryos. ATRA
14  2017 Generation of three-dimensional retinal organoids expressing rhodopsin and S- and M-cone opsins from mouse stem cells. FBS, SFEBq
15  2016 1alpha-Dihydroxyvitamin D3 and Retinoic Acid Increase Nuclear Vitamin D Receptor Expression in Monocytic THP-1 Cells. ATRA, CAMP, RAR, RXR, VDR
16  2016 Interactive effects of 9-cis-retinoic acid and androgen on proliferation, differentiation, and apoptosis of LNCaP prostate cancer cells. DHT
17  2016 Ligand Activity of Group 15 Compounds Possessing Triphenyl Substituent for the RXR and PPARgamma Nuclear Receptors. PPAR, ROSI, RXR, TPAs, TPBi, TPPO
18  2016 Radioligand binding assay for accurate determination of nuclear retinoid X receptors: A case of triorganotin endocrine disrupting ligands. Bmax
19  2015 Docking simulations suggest that all-trans retinoic acid could bind to retinoid X receptors. ATRA, RARs, RXRs
20  2015 Protein Kinase C Is Involved in the Induction of ATP-Binding Cassette Transporter A1 Expression by Liver X Receptor/Retinoid X Receptor Agonist in Human Macrophages. ABCA1, AP-1, JNK, LXRs, PI3K, PKC, RXRs
21  2015 Protein Kinase C Is Involved in the Induction of ATP-Binding Cassette Transporter A1 Expression by Liver X Receptor/Retinoid X Receptor Agonist in Human Macrophages. ABCA1, AP-1, JNK, LXRs, PI3K, PKC, RXRs
22  2015 Retinoid X receptor alpha overexpression alleviates mitochondrial dysfunction-induced insulin resistance through transcriptional regulation of insulin receptor substrate 1. IRS-1, OXPHOS, PPARdelta, RXRalpha
23  2015 Transactivation of the human retinoid X receptor by organotins: use of site-directed mutagenesis to identify critical amino acid residues for organotin-induced transactivation. PPARgamma, RXR, TBT, TPT
24  2015 Vitamin A and Diabesity: New Insight for Drug Discovery. JNK, RBP4, STRA6, TLR4
25  2014 Activation of RAS/ERK alone is insufficient to inhibit RXRalpha function and deplete retinoic acid in hepatocytes. 4-keto-RA, ATRA, RAR, RXRalpha
26  2014 beta-Apo-13-carotenone regulates retinoid X receptor transcriptional activity through tetramerization of the receptor. RXRE-Luc
27  2014 Human FXR regulates SHP expression through direct binding to an LRH-1 binding site, independent of an IR-1 and LRH-1. CDCA, DR-2, IR-1, LRH-1, SHP
28  2014 Induced differentiation of human myeloid leukemia cells into M2 macrophages by combined treatment with retinoic acid and 1alpha,25-dihydroxyvitamin D3. ATRA
29  2014 NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma. ALDH1, ATRA, CIN, MM, NEK2, RARalpha, RXRalpha, TICs
30  2014 Retinoic acids change gene expression profiles of bovine intramuscular adipocyte differentiation, based on microarray analysis. ATRA, BIP, RA, VA
31  2014 Unexpected phenotypes of malformations induced in Xenopus tropicalis embryos by combined exposure to triphenyltin and 9-cis-retinoic acid. TPT
32  2013 9-Cis retinoic acid protects against methamphetamine-induced neurotoxicity in nigrostriatal dopamine neurons. BMP-7, MA, TH
33  2013 Inflammatory mediators increase SUMOylation of retinoid X receptor alpha in a c-Jun N-terminal kinase-dependent manner in human hepatocellular carcinoma cells. JNK, NR, SUMO, TNF-alpha
34  2012 BAPJ69-4A: a yeast two-hybrid strain for both positive and negative genetic selection. RXR
35  2012 Early post-treatment with 9-cis retinoic acid reduces neurodegeneration of dopaminergic neurons in a rat model of Parkinson's disease. DA, PD, RA
36  2012 Identification and characterisation of STMN4 and ROBO2 gene involvement in neuroblastoma cell differentiation. ---
37  2012 NR4A nuclear receptors mediate carnitine palmitoyltransferase 1A gene expression by the rexinoid HX600. CPT1A, HEK, RXRs
38  2011 Analysis, occurrence, and function of 9-cis-retinoic acid. RA, RAR, RXR
39  2011 Cloning and characterization of retinoid X receptor (RXR) isoforms in the rock shell, Thais clavigera. RXR, TBT, TcRXR-1, TPT
40  2011 CrbpI modulates glucose homeostasis and pancreas 9-cis-retinoic acid concentrations. CrbpI
41  2011 Early in vitro passages of breast cancer cells are differentially susceptible to retinoids and differentially express RARbeta isoforms. 4-HPR, ATRA, EPBCCs, RARs, RXRs
42  2011 Role of ERK1/2 activation in microtubule stabilization and glucose transport in cardiomyocytes. MEK, MTOC
43  2010 All-trans- and 9-cis-retinoic acids activate the human cyclooxynase-2 gene: a role for DR1 as RARE or RXRE. DR1, tRA
44  2010 Identification of 9-cis-retinoic acid as a pancreas-specific autacoid that attenuates glucose-stimulated insulin secretion. ATRA, DIO, GK, GLUT2, GSIS, RARs, RXRs
45  2010 p27(Kip1) deficiency promotes prostate carcinogenesis but does not affect the efficacy of retinoids in suppressing the neoplastic process. BPH, DLP, MNU, PECP
46  2010 Structure, energetics, and dynamics of binding coactivator peptide to the human retinoid X receptor α ligand binding domain complex with 9-cis-retinoic acid. LBD, RXRs
47  2009 Placental steroidogenesis in rats is independent of signaling pathways induced by retinoic acids. ATRA, RAR, RAs, RXR
48  2008 9-Cis-retinoic acid reduces ischemic brain injury in rodents via bone morphogenetic protein. BMP-7, MCA, RA
49  2008 Human dendritic cell activities are modulated by the omega-3 fatty acid, docosahexaenoic acid, mainly through PPAR(gamma):RXR heterodimers: comparison with other polyunsaturated fatty acids. DCs, DHA, PPARgamma, ROSI, RXR
50  2008 Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters. CA, CDCA, mNtcp, mRNA, VAD
51  2008 Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages. CK2, LXRalpha
52  2008 RXR isoforms and endogenous retinoids in the fiddler crab, Uca pugilator. PA
53  2008 Selected natural and synthetic retinoids impair CCR7- and CXCR4-dependent cell migration in vitro and in vivo. DC, pLLP
54  2008 Synergistic growth inhibition by 9-cis-retinoic acid plus trastuzumab in human hepatocellular carcinoma cells. HCC, RXRalpha
55  2007 9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development. DC, RXR
56  2007 Ab initio fragment molecular orbital study of molecular interactions between liganded retinoid X receptor and its coactivator; part II: influence of mutations in transcriptional activation function 2 activating domain core on the molecular interactions. AF2C, CT, FMO, RXR, SRC-1, WT
57  2007 Effect of heterodimer partner RXRalpha on PPARgamma activation function-2 helix in solution. AF-2, LBD, NMR, PPARgamma, RXR
58  2007 Effect of retinoic acid on hemolymph glucose regulation in the fresh water edible crab Oziotelphusa senex senex. ATRA
59  2007 Exposure to 9-cis retinoic acid induces penis and vas deferens development in the female rock shell, Thais clavigera. RXR, TBT, TPT, VDS
60  2007 Inhibition of lung carcinogenesis by 1alpha,25-dihydroxyvitamin D3 and 9-cis retinoic acid in the A/J mouse model: evidence of retinoid mitigation of vitamin D toxicity. ---
61  2007 p38 MAPK and ERK activation by 9-cis-retinoic acid induces chemokine receptors CCR1 and CCR2 expression in human monocytic THP-1 cells. ---
62  2007 Synergistic growth inhibition by acyclic retinoid and vitamin K2 in human hepatocellular carcinoma cells. ACR, HCC, RXR
63  2006 9-cis retinoic acid induces insulin-like growth factor binding protein-3 through DR-8 retinoic acid responsive elements. IGFBP-3, IGFs, RARbeta, RARE
64  2006 9-cis-Retinoic acid inhibition of lung carcinogenesis in the A/J mouse model is accompanied by increased expression of RAR-beta but no change in cyclooxygenase-2. RARs, RXRs
65  2006 Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells. LXRs, RXRs
66  2006 Analysis of ligand binding and protein dynamics of human retinoid X receptor alpha ligand-binding domain by nuclear magnetic resonance. CPMG, ex, LBD, RXRs
67  2006 Antitumoral activity of 13-demethyl or 13-substituted analogues of all-trans retinoic acid and 9-cis retinoic acid in the human myeloid leukemia cell line HL-60. ATRA, ATRA, RARE
68  2006 Changes in functional properties of the caffeine-sensitive Ca2+ store during differentiation of human SH-SY5Y neuroblastoma cells. ---
69  2006 Differential regulation of CC chemokine receptors by 9-cis retinoic acid in the human mast cell line, HMC-1. ---
70  2006 Organ-specific expression profiles of rat mammary gland, liver, and lung tissues treated with targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide. 4-HPR, RAR, RXR
71  2006 Regulation of 5'-promoter activity of the rat growth hormone and growth hormone-releasing hormone receptor genes in the MtT/S and MtT/E cells. DEX, GH, GHRH, RA
72  2005 All-trans and 9-cis retinoic acids, retinol and beta-carotene chemopreventive activities during the initial phases of hepatocarcinogenesis involve distinct actions on glutathione S-transferase positive preneoplastic lesions remodeling and DNA damage. AtRA, betaC, PNL, ROL, ROL
73  2005 Impaired ATP-binding cassette transporter A1-mediated sterol efflux from oxidized LDL-loaded macrophages. ABCA1, AcLDL, apoAI, cpt-cAMP, ox-LDL
74  2005 Liver X receptor and retinoic X receptor agonists modulate the expression of genes involved in lipid metabolism in human endothelial cells. hFB, LXRs, RXR
75  2005 Receptor-selective retinoids inhibit the growth of normal and malignant breast cells by inducing G1 cell cycle blockade. ER-positive, HMECs
76  2005 Regression of NMU-induced mammary tumors with the combination of melatonin and 9-cis-retinoic acid. ---
77  2005 Retinoids suppress premalignant MCF10AT but not malignant MCF10CA1a breast epithelial cells in vivo. Role of retinoic acid receptor beta2 expression. ATRA
78  2005 Selective allosteric ligand activation of the retinoid X receptor heterodimers of NGFI-B and Nurr1. RXR
79  2004 Breast cancer progression in MCF10A series of cell lines is associated with alterations in retinoic acid and retinoid X receptors and with differential response to retinoids. ATRA, RARalpha, gamma, RARbeta
80  2004 Creation and discovery of ligand-receptor pairs for transcriptional control with small molecules. RXR
81  2004 Effect of LPS on basal and induced apo E secretion by 25-OH chol and 9cRA in differentiated CaCo-2. APOE, ELISA, LPS, RT-PCR
82  2004 Effect of retinoic acid and interferon alpha-2a on transitional cell carcinoma of bladder. ATRA, IFN
83  2004 Retinoic acid enhances the gene expression of human polymeric immunoglobulin receptor (pIgR) by TNF-alpha. ATRA, NF-kappaB, pIgR
84  2004 The induction of prostaglandin E synthase and upregulation of cyclooxygenase-2 by 9-cis retinoic acid. COX, LPS, PGE2, RXR, TXA2
85  2003 Activation of peroxisome proliferator-activated receptor gamma and retinoid X receptor results in net depletion of cellular cholesteryl esters in macrophages exposed to oxidized lipoproteins. ox, PPARgamma, RXR, TZDs
86  2003 Chemopreventive agents induce a senescence-like phenotype in rat mammary tumours. 9OLS, BrdU, MNU, SLC, SLP, TRS
87  2003 Effect of co-administration of retinoids on rat embryo development in vitro. 4otRA, tRA
88  2003 Effects of 9-cis- and all-trans-retinoic acids on blood glucose homeostasis in the fiddler crab, Uca pugilator. ATRA
89  2003 Growth inhibition through activation of peroxisome proliferator-activated receptor gamma in human oesophageal squamous cell carcinoma. OSCC, PI, PPARgamma, RXRalpha, TRO
90  2003 Identification and characterization of rodent ABCA1 in isolated type II pneumocytes. ABCA1, apoAI
91  2003 Isolation and characterization of unsaturated fatty acids as natural ligands for the retinoid-X receptor. RXR
92  2003 Modulation of TNF-alpha expression in bone marrow macrophages: involvement of vitamin D response element. BMMs, EMSA, RARs, RXRs, TNF-alpha, VDREs, VDRs
93  2003 Molecular mechanism for growth suppression of human hepatocellular carcinoma cells by acyclic retinoid. ERK, HCC, RXRalpha
94  2003 Structure and function of retinol dehydrogenases of the short chain dehydrogenase/reductase family. ATRA, ER, SDRs
95  2002 9-cis-retinoic acid but not 4-(hydroxyphenyl)retinamide inhibits prostate intraepithelial neoplasia in Noble rats. PIN
96  2002 Determination of endogenous levels of retinoic acid isomers in type II diabetes mellitus patients. Possible correlation with HbA1c values. HbA1c
97  2002 Phosphorylation of retinoid X receptor suppresses its ubiquitination in human hepatocellular carcinoma. HCC, MAP, RXRalpha
98  2002 Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions. RAR
99  2002 Retinoids induce the PAI-1 gene expression through tyrosine kinase-dependent pathways in vascular smooth muscle cells. ATRA, PAI-1, SMCs
100  2002 [Potentiation of arsenic trioxide-induced apoptosis by retinoic acid in retinoic acid sensitive and resistant HL-60 myeloid leukemia cells]. AML, ATRA, RA, TdT