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Abbreviation : ABCG1
Long Form : ATP-binding cassette transporter G1
No. Year Title Co-occurring Abbreviation
2022 Effects of ABCG1 knockout on proteomic composition of HDL in mice on a chow diet and a high-fat diet. apo, HDL, HFD, NCD, SAA
2022 High nuclear ABCG1 expression is a poor predictor for hepatocellular carcinoma patient survival. HCC, OS, RFS
2022 Perivascular adipose-derived exosomes reduce macrophage foam cell formation through miR-382-5p and the BMP4-PPARγ-ABCA1/ABCG1 pathways. ABCA1, BMP4, Exos, PPARgamma, PVAT
2021 Artesunate attenuates foam cell formation by enhancing cholesterol efflux. ART, ATP, ELISA, IL-6, mRNA, ox-LDL, qRT-PCR, TLR4, TNF-alpha
2021 Atrial Natriuretic Peptide Inhibited ABCA1/G1-dependent Cholesterol Efflux Related to Low HDL-C in Hypertensive Pregnant Patients. ABCA1, ANP, HDL-C, HDP, LDL-C, LXRalpha, NPR-A, PPARgamma, TC, TGs
2021 Berberine attenuates atherosclerotic lesions and hepatic steatosis in ApoE-/- mice by down-regulating PCSK9 via ERK1/2 pathway. ABCA1, BBR, HDL-C, HE, HFD, LDL, LDLR, PCSK9, SR-BI, TC, TG
2021 Diagnostic and prognostic value of ABC transporter family member ABCG1 gene in clear cell renal cell carcinoma. ABC, ccRCC, CTD, HR, OS
2021 Evodiamine Lowers Blood Lipids by Up-Regulating the PPARγ/ABCG1 Pathway in High-Fat-Diet-Fed Mice. HFD, LDL-C, PPARgamma, TBA, TC, TG
2021 Novel Metabolic Regulation of Bile Acid Responses to Low Cholesterol in Whole-Grain-Diet-Fed Mice. CYP27a1, Cyp7a1, HMGCR, LDLR, SR-BI, TC, TG
10  2021 Synergetic Effect of rHDL and LXR Agonist on Reduction of Atherosclerosis in Mice. ABCA1, HDLs, LXR, rHDL
11  2020 ABCG1 Attenuates Oxidative Stress Induced by H2O2 through the Inhibition of NADPH Oxidase and the Upregulation of Nrf2-Mediated Antioxidant Defense in Endothelial Cells. LXR
12  2020 Diabetes Impairs Cellular Cholesterol Efflux From ABCA1 to Small HDL Particles. ABCA1, ABCA1 CEC, HDL, SERPINA1
13  2020 Increased ABCA1 (ATP-Binding Cassette Transporter A1)-Specific Cholesterol Efflux Capacity in Schizophrenia. ABCA1, CEC, HDL-C, LDL-C
14  2020 Luteolin improves hypercholesterolemia and glucose intolerance through LXRalpha-dependent pathway in diet-induced obese mice. LXR, SR-B1
15  2020 Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma. HCC
16  2020 PRMT2 inhibits the formation of foam cell induced by ox-LDL in RAW 264.7 macrophage involving ABCA1 mediated cholesterol efflux. ABCA1, CE, FC, HPLC, LV-PRMT2, PRMT2, SR-A1, TC
17  2020 Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes. Ang, CD, CKD, HN, RAS, SIRT6
18  2020 The effect of genistein on lipid levels and LDLR, LXRα and ABCG1 expression in postmenopausal women with hyperlipidemia. ApoA1, apoB, EG, GEN, HDL-C, LDL-C, LDLR, LXRalpha, PG, TC, TG
19  2020 Zafirlukast prevented ox-LDL-induced formation of foam cells. ABCA1, AS, PI3K
20  2020 [Research progress on anti-atherosclerosis effect and mechanism of flavonoids compounds mediated by macrophages]. ABCA1, AS, SR, TLR
21  2019 Apolipoprotein A-I improves pancreatic beta-cell function independent of the ATP-binding cassette transporters ABCA1 and ABCG1. ABCA1, apoA-I, GSIS
22  2019 Associations of ABCG1-mediated cholesterol efflux capacity with coronary artery lipid content assessed by near-infrared spectroscopy. ACS, CAD, CEC, HDL, LCBI, NIRS
23  2019 ATP-binding cassette transporter G1 deficiency is associated with mild glucocorticoid insufficiency in mice. ---
24  2019 Attenuated cholesterol metabolism pathway suppresses regulatory T cell development in prenatal nicotine exposed female mice. GD, PNE
25  2019 Bis(monoacylglycero)phosphate regulates oxysterol binding protein-related protein 11 dependent sterol trafficking. BMP, LDL, ORPs, OSBP, oxLDL
26  2019 c-Kit suppresses atherosclerosis in hyperlipidemic mice. HFD, KitWT, SCF, SMCs
27  2019 High-Density Lipoprotein Function Is Reduced in Patients Affected by Genetic or Idiopathic Hypogonadism. ABCA1, CLC, CV, HDL-C, HDLs
28  2019 Potential roles of dietary flavonoids from Citrus aurantium L. var. amara Engl. in atherosclerosis development. ABCA1, AS, CAVA, CD36, ERK, HE, HG, IL-1beta, IL-6, JNK, LPS, NF-kappaB, NO, ox-LDL, PPARgamma, TNF-alpha
29  2018 6-Dihydroparadol, a Ginger Constituent, Enhances Cholesterol Efflux from THP-1-Derived Macrophages. ABCA1, CVD
30  2018 Ablation of Myeloid ADK (Adenosine Kinase) Epigenetically Suppresses Atherosclerosis in ApoE-/- (Apolipoprotein E Deficient) Mice. ADK, ADK
31  2018 Association of Genes in the High-Density Lipoprotein Metabolic Pathway with Polypoidal Choroidal Vasculopathy in Asian Population: A Systematic Review and Meta-Analysis. ABCA1, AMD, CETP, CIs, HDLMP, LPL, ORs, PCV, SNPs
32  2018 Depletion of Lipid Efflux Pump ABCG1 Triggers the Intracellular Accumulation of Extracellular Vesicles and Reduces Aggregation and Tumorigenesis of Metastatic Cancer Cells. EVs
33  2018 Elevating ATP-binding cassette transporter G1 improves re-endothelialization function of endothelial progenitor cells via Lyn/Akt/eNOS in diabetic mice. EPC, Tie2- ABCG1Tg, WT
34  2018 LAL (Lysosomal Acid Lipase) Promotes Reverse Cholesterol Transport In Vitro and In Vivo. ABCA1, ABCG8, LAL
35  2018 Placental mechanism of prenatal nicotine exposure-reduced blood cholesterol levels in female fetal rats. ABCA1, HDL-C, IUGR, LDL-C, LXR, PNE, SR-B1, TCH
36  2018 PPAR-gamma pathways attenuate pulmonary granuloma formation in a carbon nanotube induced murine model of sarcoidosis. MWCNT, PPARgamma
37  2018 Silencing ZAP70 prevents HSP65-induced reverse cholesterol transport and NF-kappaB activation in T cells. ABCA1, LXRalpha, NF-kappaB, PPARgamma, SR-BI, TCR, ZAP-70
38  2017 ABCG1 as a potential oncogene in lung cancer. ---
39  2017 Effects of Astaxanthin on Reverse Cholesterol Transport and Atherosclerosis in Mice. ABCA1, AS, HDL-C, RCT, SR-BI
40  2017 Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier. ABC, AD, apo, BBB, LXR, PBCEC, SR-BI
41  2017 Nucleolin protects macrophages from oxLDL-induced foam cell formation through up-regulating ABCA1 expression. ABCA1, ActD, Co-IP, HFD, HPLC, ox-LDL, SR
42  2017 Pectin penta-oligogalacturonide reduces cholesterol accumulation by promoting bile acid biosynthesis and excretion in high-cholesterol-fed mice. ABCA1, apoA-I, BA, BSEP, CYP7A1, FXR, HCD, HDL-C, RCT, SR-BI
43  2016 Advanced glycation end products increase lipids accumulation in macrophages through upregulation of receptor of advanced glycation end products: increasing uptake, esterification and decreasing efflux of cholesterol. AGEs, HMGCR, oxLDL, SR
44  2016 Analysis of Serum Cholesterol Efflux Capacity in a Minipig Model of Nonischemic Heart Failure. ABCA1, CEC, HDL-C, HF, PD, SR-BI
45  2016 Intracellular Localization of Endogenous Mouse ABCG1 Is Mimicked by Both ABCG1-L550 and ABCG1-P550-Brief Report. ---
46  2016 Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. LDLR-deficient, LNs
47  2016 MEK1/2 inhibitors activate macrophage ABCG1 expression and reverse cholesterol transport-An anti-atherogenic function of ERK1/2 inhibition. LXR, LXRE, RCT
48  2016 Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages. ABCA1, CHE, SR-B1
49  2016 The critical role of ABCG1 and PPARgamma/LXRalpha signaling in TLR4 mediates inflammatory responses and lipid accumulation in vascular smooth muscle cells. LXRalpha, ox-LDL, PPARgamma, siRNA, TLR4, VSMCs
50  2016 [In vitro effect and mechanistic study of compound E23869 on lipid metabolism]. ABCA1, CLA-1, SR-BI
51  2015 Coenzyme Q10 consumption promotes ABCG1-mediated macrophage cholesterol efflux: a randomized, double-blind, placebo-controlled, cross-over study in healthy volunteers. CoQ10, MDMs
52  2015 Dysfunctional HDL and atherosclerotic cardiovascular disease. ABCA1, HDLs
53  2015 High-density lipoprotein-mediated transcellular cholesterol transport in mouse aortic endothelial cells. apoAI, HDL, MAECs, PI3K
54  2015 Identification of an Amino Acid Residue Critical for Plasma Membrane Localization of ATP-Binding Cassette Transporter G1--Brief Report. hABCG1, mABCG1
55  2015 Propofol up-regulates expression of ABCA1, ABCG1, and SR-B1 through the PPARgamma/LXRalpha signaling pathway in THP-1 macrophage-derived foam cells. ABCA1, PPARgamma, SR-B1
56  2015 Selective inhibition of liver X receptor alpha-mediated lipogenesis in primary hepatocytes by licochalcone A. ABCA1, LicA, LXRalpha, LXRE, RCT, SREBP-1c
57  2015 The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity. ---
58  2015 [Effect of ferulic acid on cholesterol efflux in macrophage foam cell formation and potential mechanism]. ABCA1, AS, ox-LDL, RCT
59  2014 3beta,5alpha,6beta-Cholestanetriol and 25-hydroxycholesterol accumulate in ATP-binding cassette transporter G1 (ABCG1)-deficiency. CT, HC
60  2014 ABCG1 is required for pulmonary B-1 B cell and natural antibody homeostasis. NAb
61  2014 ABCG1 rs57137919G>a polymorphism is functionally associated with varying gene expression and apoptosis of macrophages. CAD, RCT
62  2014 Association between ABCG1 polymorphism rs1893590 and high-density lipoprotein (HDL) in an asymptomatic Brazilian population. BMI, HDL
63  2014 Caveolin-1 interacts with ATP binding cassette transporter G1 (ABCG1) and regulates ABCG1-mediated cholesterol efflux. Cav-1
64  2014 HDL biogenesis, remodeling, and catabolism. ABCA1, apoA-I, apoM, CETP, EL, HL, LCAT, PLTP, SR-BI
65  2014 Markers of increased cardiovascular risk in patients with chronic kidney disease. ABCA1, CAD, CKD, Gla, MMP-2, MMP-9, TIMP-1, TIMP-2
66  2014 Signal transduction by HDL: agonists, receptors, and signaling cascades. ABCA1, apoA-I, HDL, S1P
67  2014 [Decline of ATP-binding cassette transporter G1 expressions with a liver X receptor-independent pathway in patients with type 2 diabetes]. ApoA1, EMSA, HDL, LXR, LXRE, M-CSF, qRT-PCR
68  2013 ATP-binding cassette transporter G1 protects against endothelial dysfunction induced by high glucose. HAECs, LXR, ROS
69  2013 Characterization of palmitoylation of ATP binding cassette transporter G1: effect on protein trafficking and function. C311A
70  2013 Characterization of the role of a highly conserved sequence in ATP binding cassette transporter G (ABCG) family in ABCG1 stability, oligomerization, and trafficking. ABCG
71  2013 Effect of apoA-I Mutations in the Capacity of Reconstituted HDL to Promote ABCG1-Mediated Cholesterol Efflux. apoA-I, HDL, rHDL
72  2013 HMG-CoA reductase inhibitors, simvastatin and atorvastatin, downregulate ABCG1-mediated cholesterol efflux in human macrophages. ---
73  2013 Impact of serum amyloid A on cellular cholesterol efflux to serum in type 2 diabetes mellitus. SAA, SR-BI
74  2013 Porphyromonas gingivalis lipopolysaccharide increases lipid accumulation by affecting CD36 and ATP-binding cassette transporter A1 in macrophages. HO-1, ox-LDL, P. gingivalis LPS, shRNA
75  2013 Species variation in ABCG1 isoform expression: implications for the use of animal models in elucidating ABCG1 function. HDL
76  2012 ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development. iNKT
77  2012 Involvement of cholesterol efflux pathway in the control of cardiomyocytes cholesterol homeostasis. ABCA1, apoAI, CE, FC, LXR/RXR
78  2012 Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis. ABC, LXRalpha, ox-LDL, SR-A
79  2012 Sage weed (Salvia plebeia) extract antagonizes foam cell formation and promotes cholesterol efflux in murine macrophages. ABCA1, APOE, HDL, LDL, SR
80  2012 Supplementation with cyanidin-3-O-beta-glucoside protects against hypercholesterolemia-mediated endothelial dysfunction and attenuates atherosclerosis in apolipoprotein E-deficient mice. 7-KC, C3G, cGMP, eNOS, HCD
81  2012 [Endothelial dysfunction induced by high glucose is associated with decreased ATP-binding cassette transporter G1 expression]. eNOS, HAECs
82  2011 A polymorphism in the ABCG1 promoter is functionally associated with coronary artery disease in a Chinese Han population. CAD, MI, PCR-LDR, SNPs, UTR
83  2011 ATP binding cassette transporter G1 (ABCG1) is an intracellular sterol transporter. ABC, ER, HDL, INSIG2, SREBP-2, TM
84  2011 Genetic variation in ABCG1 and risk of myocardial infarction and ischemic heart disease. IHD, MI, Sp1
85  2011 Identification of an amino acid residue in ATP-binding cassette transport G1 critical for mediating cholesterol efflux. apoA-I, C514A
86  2011 Lentivirus-ABCG1 instillation reduces lipid accumulation and improves lung compliance in GM-CSF knock-out mice. EGFP, GM-CSF, KO, PAP, PPARgamma
87  2010 Adenosine monophosphate-activated protein kinase induces cholesterol efflux from macrophage-derived foam cells and alleviates atherosclerosis in apolipoprotein E-deficient mice. AICAR, AMPK, SR-BI
88  2010 An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells. TZDs
89  2010 ATP binding cassette G1-dependent cholesterol efflux during inflammation. AP, apoA-I, PL, SAA, SAA
90  2010 ATP-binding cassette transporter G1 and high-density lipoprotein promote endothelial NO synthesis through a decrease in the interaction of caveolin-1 and endothelial NO synthase. Cav, ECs, eNOS, HDL
91  2010 Group X secretory phospholipase A2 negatively regulates ABCA1 and ABCG1 expression and cholesterol efflux in macrophages. ABCA1, GX, LXR
92  2010 Increased atherosclerosis in mice with vascular ATP-binding cassette transporter G1 deficiency--brief report. ---
93  2010 Overexpression of the steroidogenic acute regulatory protein increases the expression of ATP-binding cassette transporters in microvascular endothelial cells (bEnd.3). ATP, FACS, PCR, StAR
94  2010 Participation of lipid transport and fatty acid metabolism in valproate sodium-induced hepatotoxicity in HepG2 cells. AST, CPT1A, CYP1A1, LDH, VPA
95  2010 Postprandial lipemia enhances the capacity of large HDL2 particles to mediate free cholesterol efflux via SR-BI and ABCG1 pathways in type IIB hyperlipidemia. CE, CETP, FC, SR-BI
96  2010 Restoration of PPARgamma reverses lipid accumulation in alveolar macrophages of GM-CSF knockout mice. GM-CSF, KO, PAP
97  2009 ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation. ---
98  2009 Genotypic Effect of ABCG1 gene promoter -257T>G polymorphism on coronary artery disease severity in Japanese men. CAD, HDL
99  2009 Independent protective roles for macrophage Abcg1 and Apoe in the atherosclerotic lesion development. APOE, DKO, KO, WT
100  2009 Lack of Abcg1 results in decreased plasma HDL cholesterol levels and increased biliary cholesterol secretion in mice fed a high cholesterol diet. RCT