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Abbreviation : ABHD6
Long Form : alpha/beta-hydrolase domain-containing 6
No. Year Title Co-occurring Abbreviation
2022 Motor-like Tics are Mediated by CB2 Cannabinoid Receptor-dependent and Independent Mechanisms Associated with Age and Sex. Delta9-THC, DOI, ESR, FAAH, HTR, TS
2022 α/β-Hydrolase Domain-Containing 6 (ABHD6)- A Multifunctional Lipid Hydrolase. MAG
2021 ABHD6 Controls Amphetamine-Stimulated Hyperlocomotion: Involvement of CB1 Receptors. AS, CB1Rs, eCBs, KO, MAGL, WT
2021 Alpha/Beta-Hydrolase Domain-Containing 6: Signaling and Function in the Central Nervous System. 2-AG, CNS, eCB, MAG, MS, TBI
2021 Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status. CPT1C, WT
2021 Design and Synthesis of Highly Potent and Specific ABHD6 Inhibitors. 2-AG, MAGs, MGL
2021 The endocannabinoid 2-arachidonoylglycerol and dual ABHD6/MAGL enzyme inhibitors display neuroprotective and anti-inflammatory actions in the in vivo retinal model of AMPA excitotoxicity. 2-AG, MAGL, PI3K
2021 UPLC-MS/MS Method for Analysis of Endocannabinoid and Related Lipid Metabolism in Mouse Mucosal Tissue. DGL, FAAH, FAEs, MAGs, MGL
2020 Termination of acute stress response by the endocannabinoid system is regulated through lysine-specific demethylase 1-mediated transcriptional repression of 2-AG hydrolases ABHD6 and MAGL. 2-AG, CB1, eCB, ECS, LSD1, MAGL
10  2020 Therapeutic potential of targeting alpha/beta-Hydrolase domain-containing 6 (ABHD6). 2-AG, MAG
11  2019 ABHD6: Its Place in Endocannabinoid Signaling and Beyond. eCB
12  2019 Cutting Edge: Dysregulated Endocannabinoid-Rheostat for Plasmacytoid Dendritic Cell Activation in a Systemic Lupus Endophenotype. 2-AG, CB2, pDCs, SLE
13  2019 Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans. BMP, LSDs
14  2018 Deregulation of the endocannabinoid system and therapeutic potential of ABHD6 blockade in the cuprizone model of demyelination. 2-AG, MS, PEA
15  2018 Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors. FAAH, MAGL
16  2018 Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis. 2-AG, CNS, EAE, MS
17  2018 The Endocannabinoid System across Postnatal Development in Transmembrane Domain Neuregulin 1 Mutant Mice. CB1R, DAGLalpha, MGLL, NRG1, PNDs
18  2017 The Inhibitory Effect of alpha/beta-Hydrolase Domain-Containing 6 (ABHD6) on the Surface Targeting of GluA2- and GluA3-Containing AMPA Receptors. AMPA
19  2016 A Sensitive and Versatile Fluorescent Activity Assay for ABHD6. 2-AG, MAGL
20  2016 alpha/beta-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors. AMPARs
21  2015 alpha/beta Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate. BMP
22  2015 Comparative molecular field analysis and molecular dynamics studies of alpha/beta hydrolase domain containing 6 (ABHD6) inhibitors. 2-AG, CoMFA
23  2013 Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of alpha/beta-hydrolase domain containing 6 (ABHD6). 2-AG
24  2012 Biochemical and pharmacological characterization of human alpha/beta-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12). 2-AG, ABHD, MAGL
25  2012 Highly predictive ligand-based pharmacophore and homology models of ABHD6. ---
26  2009 High expression of the evolutionarily conserved alpha/beta hydrolase domain containing 6 (ABHD6) in Ewing tumors. EFT