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Abbreviation : ABP
Long Form : 4-aminobiphenyl
No. Year Title Co-occurring Abbreviation
2020 Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes. 2-AF, DMA, EA, NAT1, NAT2, NER
2020 The impact of sex on hepatotoxic, inflammatory and proliferative responses in mouse models of liver carcinogenesis. DEN, HBV, HBV-Tg
2019 Role of Human N-Acetyltransferase 2 Genetic Polymorphism on Aromatic Amine Carcinogen-Induced DNA Damage and Mutagenicity in a Chinese Hamster Ovary Cell Mutation Assay. AF, CHO, HPRT, NAT2
2018 DNA base sequence effects on bulky lesion-induced conformational heterogeneity during DNA replication. AF
2018 Strong impact of sulfotransferases on DNA adduct formation by 4-aminobiphenyl in bladder and liver in mice. SULT
2017 Catalytic properties and heat stabilities of novel recombinant human N-acetyltransferase 2 allozymes support existence of genetic heterogeneity within the slow acetylator phenotype. DMABP, NAT2, SMZ
2017 Error-Prone and Error-Free Translesion DNA Synthesis over Site-Specifically Created DNA Adducts of Aryl Hydrocarbons (3-Nitrobenzanthrone and 4-Aminobiphenyl). AAF, BaP, dG-N2-ABA, NBA, NP, TLS
2017 Molecular Interactions of Carcinogenic Aromatic Amines, 4-Aminobiphenyl and 4,4'-Diaminobiphenyl, with Lactoperoxidase - Insight to Breast Cancer. LPO
2016 Effects of benzo[a]pyrene, aromatic amines, and a combination of both on CYP1A1 activities in RT-4 human bladder papilloma cells. BaP, CYP1A1, NA, PAH
10  2016 Influence of sex and developmental stage on acute hepatotoxic and inflammatory responses to liver procarcinogens in the mouse. ALT, DEN, IL-6, Nrf2
11  2015 N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer. ---
12  2015 Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice. NAT1
13  2015 The inverse relationship between bladder and liver in 4-aminobiphenyl-induced DNA damage. UGTs
14  2013 Elevated 4-aminobiphenyl and 2,6-dimethylaniline hemoglobin adducts and increased risk of bladder cancer among lifelong nonsmokers--The Shanghai Bladder Cancer Study. 2,6-DMA, CI
15  2012 Influence of arylamine N-acetyltransferase, sex, and age on 4-aminobiphenyl-induced in vivo mutant frequencies and spectra in mouse liver. ---
16  2012 Reducing health risk assigned to organic emissions from a chemical weapons incinerator. PAH
17  2011 Identification of an unintended consequence of Nrf2-directed cytoprotection against a key tobacco carcinogen plus a counteracting chemopreventive intervention. Nrf2, UGT
18  2011 NATb/NAT1*4 promotes greater arylamine N-acetyltransferase 1 mediated DNA adducts and mutations than NATa/NAT1*4 following exposure to 4-aminobiphenyl. NAT1, NER, UTR
19  2011 Reduced 4-aminobiphenyl-induced liver tumorigenicity but not DNA damage in arylamine N-acetyltransferase null mice. NAT
20  2010 Sulforaphane inhibits 4-aminobiphenyl-induced DNA damage in bladder cells and tissues. Nrf2, SF
21  2009 Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenyl-induced DNA adducts and mutations. CHO, CYP1A1, HPRT, NAT2
22  2008 The dual roles of Ganoderma antioxidants on urothelial cell DNA under carcinogenic attack. DPPH, FRAP, TCM
23  2007 Carcinogen-induced histone alteration in normal human mammary epithelial cells. HMECs, LSD1
24  2007 Hair dye use, meat intake, and tobacco exposure and presence of carcinogen-DNA adducts in exfoliated breast ductal epithelial cells. PhIP
25  2006 CYP2A13 expressed in human bladder metabolically activates 4-aminobiphenyl. ---
26  2006 In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice. AF, AUC, NATs
27  2006 Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster. NAT1
28  2004 Alkylaniline-hemoglobin adducts and risk of non-smoking-related bladder cancer. 2-EA, CI, RR
29  2004 Carotenoids/vitamin C and smoking-related bladder cancer. CYP1A2, NAT1, NAT2
30  2004 Lactoperoxidase-catalyzed activation of carcinogenic aromatic and heterocyclic amines. PhIP
31  2003 4-aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(+/+) mice. CYP1A2, TCDD
32  2003 Heat shock proteins hsp32 and hsp70 as biomarkers of an early response? In vitro induction of heat shock proteins after exposure of cell culture to carcinogenic compounds and their real mixtures. ACN, HSP, NP, PAHs
33  2003 Nonsmoking-related arylamine exposure and bladder cancer risk. ---
34  2003 Transformation and activation of benzidine by oxidants of the inflammatory response. 4'-OH-ABP, AZO-BZ, BZ, DEA, RNOS
35  2002 Carcinogen-DNA adducts in human breast epithelial cells. PhIP
36  2002 Decrease in 4-aminobiphenyl-induced methemoglobinemia in Cyp1a2(-/-) knockout mice. ---
37  2002 Identification of N-(deoxyguanosin-8-yl)-4-azobiphenyl by (32)P-postlabeling analyses of DNA in human uroepithelial cells exposed to proximate metabolites of the environmental carcinogen 4-aminobiphenyl. dGp, HUC, N-OH-AABP, N-OH-ABP
38  2002 Identification of new DNA adducts in human bladder epithelia exposed to the proximate metabolite of 4-aminobiphenyl using 32P-postlabeling method. dGp, HUC, N-OAc-ABP, N-OH-ABP
39  2001 DNA damage in human transitional cell carcinoma cells after exposure to the proximate metabolite of the bladder carcinogen 4-aminobiphenyl. BHA, DCF, N-OH-AABP, ROS, TCC
40  2001 Gender- and smoking-related bladder cancer risk. ---
41  2001 Role of TP53 in repair of N-(deoxyguanosin-8-yl)-4-aminobiphenyl adducts in human transitional cell carcinoma of the urinary bladder. N-OH-AABP, TCC
42  2001 Using base-specific Salmonella tester strains to characterize the types of mutation induced by benzidine and benzidine congeners after reductive metabolism. BZ, DCBz, DMBz, DMOBz, TB
43  1999 Comparison of DNA adduct levels associated with exogenous and endogenous exposures in human pancreas in relation to metabolic genotype. 8-oxodG, AAs, GST, NAT1, NQO1
44  1999 Effects of chemoprotective agents on the metabolic activation of the carcinogenic arylamines PhIP and 4-aminobiphenyl in human and rat liver microsomes. PhIP
45  1999 Standardization and validation of DNA adduct postlabelling methods: report of interlaboratory trials and production of recommended protocols. BaP, MNU, PAH, PhIP
46  1998 Specificity of mutagenesis by 4-aminobiphenyl: mutations at G residues in bacteriophage M13 DNA and G-->C transversions at a unique dG(8-ABP) lesion in single-stranded DNA. ---
47  1997 Aromatic amine DNA adduct formation in chronically-exposed mice: considerations for human comparison. AAF
48  1997 Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl-DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation. NAT
49  1997 Metabolic activation of aromatic amines by human pancreas. ---
50  1996 Cytochrome P4501A2: enzyme induction and genetic control in determining 4-aminobiphenyl-hemoglobin adduct levels. CYP1A2, Hb
51  1995 Metabolic activation of the N-hydroxy derivative of the carcinogen 4-aminobiphenyl by human tissue sulfotransferases. DHEA-ST, DHEA-ST, N-OH, TL PST, TS PST
52  1995 Metabolism of 4-aminobiphenyl and 4-acetylaminobiphenyl in perfused guinea pig liver. AABP, GABP, N-OH ABP
53  1995 Modeling human interindividual variability in metabolism and risk: the example of 4-aminobiphenyl. ---
54  1994 A selective synthesis of 4-aminobiphenyl-N2-deoxyguanosine adducts. ---
55  1994 Acetylator phenotype, aminobiphenyl-hemoglobin adduct levels, and bladder cancer risk in white, black, and Asian men in Los Angeles, California. Hb
56  1994 Metabolic activation of N-hydroxy-4-acetylaminobiphenyl by cultured human breast epithelial cell line MCF 10A. AABP, AcCoA, N-OH-AABP, N-OH-ABP
57  1994 Mutations induced by aromatic amine DNA adducts in pBR322. AAF, AF, AP
58  1994 Relationship between in vivo acetylator phenotypes and cytosolic N-acetyltransferase and O-acetyltransferase activities in human uroepithelial cells. AFMU, N-OH-ABP, NAT, OAT
59  1993 Analysis of DNA adducts in smokers' lung and urothelium by 32P-postlabelling: metabolic phenotype dependence and comparisons with other exposure markers. BaP
60  1993 Black (air-cured) and blond (flue-cured) tobacco cancer risk. IV: Molecular dosimetry studies implicate aromatic amines as bladder carcinogens. Hb, PhIP
61  1993 Carcinogen-induced amplification of SV40 DNA inserted at 9q12-21.1 associated with chromosome breakage, deletions, and translocations in human uroepithelial cell transformation in vitro. FISH, MCA, SV-HUC
62  1993 Mutagenic activation of 4-aminobiphenyl and its N-hydroxy derivatives by microsomes from cultured human uroepithelial cells. AABP, HPLC, HUC, N-OAc-ABP, N-OH-AABP, N-OH-ABP, OAT
63  1993 Phenobarbital, drug metabolism, and human cancer. PB
64  1992 Acetyl transferase-mediated metabolic activation of N-hydroxy-4-aminobiphenyl by human uroepithelial cells. AABP, AcCoA, HUC, N-OH-ABP
65  1992 Carcinogen-DNA adducts in cultures of rat and human hepatocytes. AAF, BP
66  1992 Induction of thioguanine-resistant mutations in human uroepithelial cells by 4-aminobiphenyl and its N-hydroxy derivatives. HGPRT, HUC, N-OAc-AABP, N-OH-AABP, N-OH-ABP, TGr
67  1992 Metabolism and nucleic acid binding of N-hydroxy-4-acetylaminobiphenyl and N-acetoxy-4-acetylaminobiphenyl by cultured human uroepithelial cells. AABP, HUC, N-OAc-AABP, N-OH-AABP
68  1992 Microsome-mediated transacetylation and binding of N-hydroxy-4-aminobiphenyl to nucleic acids by hepatic and bladder tissues from dog. AABP, AcCoA, N-OH-AABP, N-OH-ABP
69  1992 NMR structural studies of a 15-mer DNA sequence from a ras protooncogene, modified at the first base of codon 61 with the carcinogen 4-aminobiphenyl. ---
70  1992 Point mutation analysis of ras genes in spontaneous and chemically induced C57Bl/10J mouse liver tumours. AAF, DEN
71  1992 Tumorigenic transformation and neoplastic progression of human uroepithelial cells after exposure in vitro to 4-aminobiphenyl or its metabolites. N-OH-AABP, N-OH-ABP
72  1991 Critical considerations in the immunochemical detection and quantitation of antigenic biomarkers. PCFIA
73  1991 Frequency of urination and its effects on metabolism, pharmacokinetics, blood hemoglobin adduct formation, and liver and urinary bladder DNA adduct levels in beagle dogs given the carcinogen 4-aminobiphenyl. N-OH-ABP
74  1991 Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon. AcCoA, N-OH, PhIP
75  1991 The metabolism of 4-aminobiphenyl in rat. II. Reaction of N-hydroxy-4-aminobiphenyl with rat blood in vitro. N-hydroxy-ABP, nitroso-BP
76  1991 The metabolism of 4-aminobiphenyl in rat. III. Urinary metabolites of 4-aminobiphenyl. 2'-hydroxy-AABP, 3',4'-dihydroxy-AABP, 3'-hydroxy-4'methoxy-AABP, 4'-hydroxy-3'-methoxy-AABP, 4'-hydroxy-AABP, 4'-hydroxy-ABP, AABP, BABP, N-hydroxy-AABP, nitroso-BP
77  1990 Carcinogen hemoglobin adducts, urinary mutagenicity, and metabolic phenotype in active and passive cigarette smokers. air-cured
78  1990 Carcinogenic aromatic amine metabolism and DNA adduct detection in humans. ---
79  1990 Comparative survival of aminobiphenyl- and aminofluorene-substituted plasmid DNA in Escherichia coli Uvr endonuclease deficient strains. AF
80  1990 Detection and characterization of carcinogen-DNA adducts in exfoliated urothelial cells from 4-aminobiphenyl-treated dogs by 32P-postlabelling and subsequent thin-layer and high-pressure liquid chromatography. ---
81  1990 Hemoglobin-carcinogen adducts as molecular biomarkers in epidemiology. BaP, Hb, PAH
82  1989 Kinetic characterization of acetylator genotype-dependent and -independent N-acetyltransferase isozymes in homozygous rapid and slow acetylator inbred hamster liver cytosol. AcCoA, AF, NAT, PABA
83  1989 Metabolic oxidation of the carcinogens 4-aminobiphenyl and 4,4'-methylene-bis(2-chloroaniline) by human hepatic microsomes and by purified rat hepatic cytochrome P-450 monooxygenases. MOCA
84  1988 Immunochemical quantitation of DNA adducts derived from the human bladder carcinogen 4-aminobiphenyl. ---
85  1988 Specificity of mutagenesis by 4-aminobiphenyl. A possible role for N-(deoxyadenosin-8-yl)-4-aminobiphenyl as a premutational lesion. ---
86  1987 Acetylator genotype-dependent metabolic activation of carcinogenic N-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: relationship to arylamine N-acetyltransferase. AcCoA, AF, N-OH
87  1987 Circular dichroism of poly(dG-dC) modified by the carcinogens N-methyl-4-aminoazobenzene or 4-aminobiphenyl. CD, MAB
88  1986 Analytical methods for assessing exposure to 4-aminobiphenyl based on protein adduct formation. ---
89  1986 Development of an avidin-biotin amplified enzyme-linked immunoassay for detection of DNA adducts of the human bladder carcinogen 4-aminobiphenyl. AB-ELISA, KLH
90  1984 In vivo dosimetry of 4-aminobiphenyl in rats via a cysteine adduct in hemoglobin. ---
91  1983 Arylamine-DNA adducts in vitro and in vivo: their role in bacterial mutagenesis and urinary bladder carcinogenesis. 1-NA, 2-NA, AAF, ABZ, AF, BZ, NBP
92  1981 Arylhydroxylamine-induced ribonucleic acid chain cleavage and chromatographic analysis of arylamine-ribonucleic acid adducts. HPLC, N-OH-AABP, N-OH-AF