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Abbreviation : ABPP
Long Form : activity-based protein profiling
No. Year Title Co-occurring Abbreviation
2022 A ligand selection strategy to customize small molecule probes for activity-based protein profiling (LS-ABPP). ABPs, LS, PFP
2022 ABPP-HT*-Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods. DDA, DIA, DUBs, MS
2022 Activity-Based Protein Profiling (ABPP) for Cellular Deubiquitinase (DUB) and Inhibitor Profiling at Deep and High-Throughput Levels. DUB, DUBs
2022 Activity-Based Protein Profiling for the Identification of Novel Carbohydrate-Active Enzymes Involved in Xylan Degradation in the Hyperthermophilic Euryarchaeon Thermococcus sp. Strain 2319x1E. MS
2022 Activity-based protein profiling identifies alternating activation of enzymes involved in the bifidobacterium shunt pathway or mucin degradation in the gut microbiome response to soluble dietary fiber. ---
2022 Activity-based protein profiling of a surfactin-producing nonribosomal peptide synthetase in Bacillus subtilis. NRPSs
2022 Activity-based Protein Profiling of Serine Hydrolase Superfamily Enzymes. FP
2022 Activity-Based Protein Profiling Probe for the Detection of Enzymes Catalyzing Polysorbate Degradation. CHO, FP-biotin
2022 Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis. LPS
10  2022 Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1. CETSA, HO-1, HSCs, PRDXs, ROS
11  2022 Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect. Cel, CETSA, HMGB1, IL, LDHA, LPS, PKM2, SPR
12  2022 Chemoproteomics-Enabled Identification of 4-Oxo-β-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. ---
13  2022 Detecting and identifying glycoside hydrolases using cyclophellitol-derived activity-based probes. ABPs, GHs
14  2022 Detection of Apoplastic Protease Inhibitors Using Convolution Activity-Based Protein Profiling. ---
15  2022 Deubiquitinase Vulnerabilities Identified through Activity-Based Protein Profiling in Non-Small Cell Lung Cancer. DUBs, NSCLC
16  2022 Discovering monoacylglycerol lipase inhibitors by a combination of fluorogenic substrate assay and activity-based protein profiling. 2-AG, MAGL
17  2022 Discovery of Leishmania Druggable Serine Proteases by Activity-Based Protein Profiling. SHs, SPs
18  2022 Discovery of Potent and Selective Inhibitors against Protein-Derived Electrophilic Cofactors. Glox, Pyvl, RP, SCRN2, SCRN3
19  2022 Dissection of Targeting Molecular Mechanisms of Aristolochic Acid-induced Nephrotoxicity via a Combined Deconvolution Strategy of Chemoproteomics and Metabolomics. AA, AAN, CETSA, OCR
20  2022 Drugging the undruggable: activity-based protein profiling offers opportunities for targeting the KLK activome. KLK, PCa
21  2022 Glycyrrhizic Acid Mitigates Tripterygium-Glycoside-Tablet-Induced Acute Liver Injury via PKM2 Regulated Oxidative Stress. AKP, AST, CAT, GA, IL-1beta, IL-6, LDH, MDA, SOD, TGT, TNF-alpha
22  2022 Identification of antimalarial targets of chloroquine by a combined deconvolution strategy of ABPP and MS-CETSA. CQ, CQP, MOA, MS-CETSA
23  2022 Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling. DUFs
24  2022 Indolin-2-one Nitroimidazole Antibiotics Exhibit an Unexpected Dual Mode of Action. MOA
25  2022 Integration of bioinformatic and chemoproteomic tools for the study of enzyme conservation in closely related bacterial species. ---
26  2022 Label-free target protein characterization for small molecule drugs: recent advances in methods and applications. CETSA, DARTS, LiP-MS, MS, PP, SIP, SPROX, TPP
27  2022 Lactucin, a Bitter Sesquiterpene from Cichorium intybus, Inhibits Cancer Cell Proliferation by Downregulating the MAPK and Central Carbon Metabolism Pathway. SLs
28  2022 Probing Monotopic Phosphoglycosyl Transferases from Complex Cellular Milieu. monoPGTs
29  2022 Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure. PAHs
30  2022 Quantitative Chemoproteomic Profiling of Targets of Au(I) Complexes by Competitive Activity-Based Protein Profiling. ---
31  2022 Quantitative Chemoproteomic Profiling with Data-Independent Acquisition-Based Mass Spectrometry. DIA, MS
32  2022 Target identification of anti-diabetic and anti-obesity flavonoid derivative (Fla-CN). AMP, IR, SPR
33  2022 The Impact of Activity-Based Protein Profiling in Malaria Drug Discovery. ---
34  2021 A Suite of Activity-Based Probes To Dissect the KLK Activome in Drug-Resistant Prostate Cancer. ABPs, KLKs, PCa
35  2021 A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. SH
36  2021 Activity-Based Hydrazine Probes for Protein Profiling of Electrophilic Functionality in Therapeutic Targets. ---
37  2021 Activity-Based Protein Profiling of Retaining alpha-Amylases in Complex Biological Samples. ---
38  2021 Chemoproteomics profiling of surfactin-producing nonribosomal peptide synthetases in living bacterial cells. NRPSs
39  2021 CIMAGE2.0: An Expanded Tool for Quantitative Analysis of Activity-Based Protein Profiling (ABPP) Data. ---
40  2021 Development and application of novel electrophilic warheads in target identification and drug discovery. ---
41  2021 Development of succinimide-based inhibitors for the mitochondrial rhomboid protease PARL. ---
42  2021 Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3. TEAD
43  2021 Distinct Activity of Endocannabinoid-Hydrolyzing Enzymes MAGL and FAAH in Key Regions of Peripheral and Central Nervous System Implicated in Migraine. ECS, FAAH, MAGL
44  2021 Effects of Chlorpyrifos on Serine Hydrolase Activities, Lipid Mediators, and Immune Responses in Lungs of Neonatal and Adult Mice. AChE, CES, CPF, eCB, FAAH, LPS, MAGL, OP, WT
45  2021 Heat Shock Cognate 70 kDa Protein Is the Target of Tetradecyl 2,3-Dihydroxybenzoate for Neuritogenic Effect in PC12 Cells. CETSA, Hsc70, siRNA
46  2021 Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling. Mtb
47  2021 Identification of NLRP3 as a covalent target of 1,6-O,O-diacetylbritannilactone against neuroinflammation by quantitative thiol reactivity profiling (QTRP). CETSA, QTRP
48  2021 Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein. LIRs, PPI
49  2021 Leaf Apoplast of Field-Grown Potato Analyzed by Quantitative Proteomics and Activity-Based Protein Profiling. ---
50  2021 Profiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling. CHO, HCCF, mAbs, PLA2G7, PLBL2, TABP
51  2021 Propargylic Se-adenosyl-l-selenomethionine: A Chemical Tool for Methylome Analysis. KOs, MTases, PIS, PMS
52  2021 Proteoform of Arabidopsis seed storage protein identified by functional proteomics approach exhibits acyl hydrolase activity during germination. SSP
53  2021 Recent advances in activity-based probes (ABPs) and affinity-based probes (AfBPs) for profiling of enzymes. ABPs, AfBPs
54  2021 Reimagining Druggability Using Chemoproteomic Platforms. PROTACs
55  2021 Short-chain reactive probes as tools to unravel the Pseudomonas aeruginosa quorum sensing regulon. QS
56  2021 Xylose-Configured Cyclophellitols as Selective Inhibitors for Glucocerebrosidase. CBE, GBA, GD
57  2020 A solvent-free delipidation method for functional validation of lipases. ---
58  2020 Activity- and reactivity-based proteomics: Recent technological advances and applications in drug discovery. ---
59  2020 Activity-Based Protein Profiling (ABPP) of Oxidoreductases. ---
60  2020 Activity-based protein profiling guided identification of urine proteinase 3 activity in subclinical rejection after renal transplantation. ---
61  2020 Activity-based protein profiling of rice (Oryza sativa L.) bran serine hydrolases. SHs
62  2020 Activity-Based Protein Profiling Reveals Potential Dasatinib Targets in Gastric Cancer. GC
63  2020 Activity-based protein profiling: Recent advances in medicinal chemistry. ABPs, FluoPol-ABPP
64  2020 Bioorthogonal Reactions in Activity-Based Protein Profiling. ---
65  2020 Characterization of Serine Hydrolases Across Clinical Isolates of Commensal Skin Bacteria Staphylococcus epidermidis Using Activity-Based Protein Profiling. Fphs
66  2020 Chemical Proteomics for Expanding the Druggability of Human Disease. ---
67  2020 Chemoproteomic Identification of Serine Hydrolase RBBP9 as a Valacyclovir-Activating Enzyme. cABPP, EME, VACV
68  2020 Detectives and helpers: Natural products as resources for chemical probes and compound libraries. CETSA, MS
69  2020 Discovery of small-molecule enzyme activators by activity-based protein profiling. ---
70  2020 Evaluation of FASN inhibitors by a versatile toolkit reveals differences in pharmacology between human and rodent FASN preparations and in antiproliferative efficacy in vitro vs. in situ in human cancer cells. FASN, FASN-TE, SH
71  2020 Fragment-Based Discovery of Irreversible Covalent Inhibitors of Cysteine Proteases Using Chlorofluoroacetamide Library. CFA
72  2020 High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections - Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils. FP, SHs, TAMs, TANs
73  2020 Monohaloacetic Acids and Monohaloacetamides Attack Distinct Cellular Proteome Thiols. DBP, mHAAs, mHAMs
74  2020 Rapid Polysorbate 80 Degradation by Liver Carboxylesterase in a Monoclonal Antibody Formulated Drug Substance at Early Stage Development. CES-B1L, A0A061I7X9, hCES-1, HCP, mAb, PS, rLES
75  2020 STA-55, an Easily Accessible, Broad-Spectrum, Activity-Based Aldehyde Dehydrogenase Probe. ALDHs
76  2020 System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion. Hb
77  2020 Systems level profiling of arginine starvation reveals MYC and ERK adaptive metabolic reprogramming. ASS1
78  2019 A Chemical Proteomic Analysis of Illudin-Interacting Proteins. ---
79  2019 ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction. ---
80  2019 Activity-based Protein Profiling Approaches for Transplantation. ---
81  2019 Activity-Based Protein Profiling Identifies alpha-Ketoamides as Inhibitors for Phospholipase A2 Group XVI. PLA2G16
82  2019 Activity-based protein profiling in bacteria: Applications for identification of therapeutic targets and characterization of microbial communities. ABPs
83  2019 Activity-based protein profiling of the human failing ischemic heart reveals alterations in hydrolase activities involving the endocannabinoid system. 2-AG, AEA, MGLL, NAEs
84  2019 Activity-based protein profiling reveals that secondary-carbon-centered radicals of synthetic 1,2,4-trioxolanes are predominately responsible for modification of protein targets in malaria parasites. ---
85  2019 Applications of Activity-Based Protein Profiling (ABPP) and Bioimaging in Drug Discovery. ---
86  2019 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ---
87  2019 Development of Novel Irreversible Pyruvate Kinase M2 Inhibitors. PKM2
88  2019 Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling. GI, GUSs
89  2019 Discovery and Optimization of Selective and in Vivo Active Inhibitors of the Lysophosphatidylserine Lipase alpha/beta-Hydrolase Domain-Containing 12 (ABHD12). ABHD12, lysoPI, LysoPS
90  2019 Global Portrait of Protein Targets of Metabolites of the Neurotoxic Compound BIA 10-2474. FAAH
91  2019 Harnessing the anti-cancer natural product nimbolide for targeted protein degradation. ---
92  2019 Human leukocytes differentially express endocannabinoid-glycerol lipases and hydrolyze 2-arachidonoyl-glycerol and its metabolites from the 15-lipoxygenase and cyclooxygenase pathways. 2-AG, AMs, MAFP, PGE2 -G
93  2019 Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology. AEA
94  2019 Prospective Application of Activity-Based Proteomic Profiling in Vision Research-Potential Unique Insights into Ocular Protease Biology and Pathology. ---
95  2019 Proteases Underground: Analysis of the Maize Root Apoplast Identifies Organ Specific Papain-Like Cysteine Protease Activity. PCD, PL, SA
96  2019 Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination. MS, PADs, PTMs, RA, UC
97  2019 Quantification of In Vivo Target Engagement Using Microfluidic Activity-Based Protein Profiling. ---
98  2019 Structure Dependent Determination of Organophosphate Targets in Mammalian Tissues Using Activity-Based Protein Profiling. OPs
99  2019 The small molecule SI113 hinders epithelial-to-mesenchymal transition and subverts cytoskeletal organization in human cancer cells. ---
100  2019 Two-Step Bioorthogonal Activity-Based Protein Profiling of Individual Human Proteasome Catalytic Sites. IEDDA