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Abbreviation : ALOX12
Long Form : arachidonate 12-lipoxygenase
No. Year Title Co-occurring Abbreviation
2021 A small molecule targeting ALOX12-ACC1 ameliorates nonalcoholic steatohepatitis in mice and macaques. NASH
2021 Antisense overlapping long non-coding RNA regulates coding arachidonate 12-lipoxygenase gene by translational interference. ALOX12-AS1, lncRNA
2021 Inhibition of Oxidative Stress and ALOX12 and NF-kappaB Pathways Contribute to the Protective Effect of Baicalein on Carbon Tetrachloride-Induced Acute Liver Injury. Fer-1, HO-1, NF-kappaB
2021 Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis. ACC1, NASH
2021 Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species. MI-R
2021 TRPV1 Hyperfunction Contributes to Renal Inflammation in Oxalate Nephropathy. IL, TRPV1
2020 Targeting of the Alox12-12-HETE in Blast Crisis Chronic Myeloid Leukemia Inhibits Leukemia Stem/Progenitor Cell Function. 12-HETE, BMP, BP, CML, HSPCs, NADPH
2020 TRPV1 Hyperfunction Involved in Uremic Toxin Indoxyl Sulfate-Mediated Renal Tubular Damage. AhR, IS, LLC-PK1, MDCK, TRPV1
2019 Effects of Early Intervention With Maternal Fecal Bacteria and Antibiotics on Liver Metabolome and Transcription in Neonatal Pigs. ACAA2, ALOX15, AM, ASS1, CO, CYP1A2, FMT, GPT2, LDL-C
10  2019 Knockout of ALOX12 protects against spinal cord injury-mediated nerve injury by inhibition of inflammation and apoptosis. GFAP, IkappaBalpha, NF-kappaB, SCI, WT
11  2018 Peri-conceptional nutritional restriction alters transcriptomic profile in the peri-implantation pig embryos. AdipoR2, HMGB2, PAQR7, PGRMC2, PTGS2, SERPINA1, StAR
12  2018 Periconceptional undernutrition affects the levels of DNA methylation in the peri-implantation pig endometrium and in embryos. AdipoR1, AdipoR2, EDNRB, HMGB2, HSD17B4, PAQR7, PGRMC2, PPAP2C, PTGS2, RGS12, SERPINA1, StAR, TLR3
13  2018 The role of vitamin C in the gene expression of oxidative stress markers in fibroblasts from burn patients. DHCR24, DUOX1, GPX2, GPX5, MGST3, P-REX1, PRDX4, PTGS1, RNF7
14  2017 An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic ischemia-reperfusion injury. IR
15  2017 Arachidonate 12-Lipoxygenase Inhibitors Promote S100A3 Citrullination in Cultured SW480 Cells and Isolated Hair Follicles. HBEGF, PADI
16  2015 Changes in PTGS1 and ALOX12 Gene Expression in Peripheral Blood Mononuclear Cells Are Associated with Changes in Arachidonic Acid, Oxylipins, and Oxylipin/Fatty Acid Ratios in Response to Omega-3 Fatty Acid Supplementation. 12-HETE, ARA, DHA, EPA, FA, IL-8, PBMCs, PE, PGE2, PTGS1, PTGS2, qPCR
17  2014 Hypoxic preconditioning protects rat hearts against ischemia-reperfusion injury via the arachidonate12-lipoxygenase/transient receptor potential vanilloid 1 pathway. HPC, IR, PKC, TRPV1
18  2012 DNA hypomethylation at ALOX12 is associated with persistent wheezing in childhood. INMA
19  2012 [The role of COX-2, ALOX12 and iNOS genes in nasal polyposis]. COX-2, iNOS, NO, NP, PCR
20  2010 ALOX12 polymorphisms are associated with fat mass but not peak bone mineral density in Chinese nuclear families. BMD, PFM, PPARG, QTDT, SNPs, TFM, TLM
21  2010 Association between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population. AA, BPRS, OPCRIT, SANS, SNP
22  2007 Polymorphisms in ALOX12, but not ALOX15, are significantly associated with BMD in postmenopausal women. ALOX15, BMD, SNPs
23  1995 A TaqI polymorphism at the porcine arachidonate 12-lipoxygenase (ALOX12) locus. ---