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Abbreviation : APLN
Long Form : apelin
No. Year Title Co-occurring Abbreviation
2022 A Tead1-Apelin axis directs paracrine communication from myogenic to endothelial cells in skeletal muscle. TEAD1
2022 Apelin and Apelin Receptor in Follicular Granulosa Cells of Buffalo Ovaries: Expression and Regulation of Steroidogenesis. FSH, GCs
2022 Elabela Attenuates the TGF-β1-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells in Patients Receiving Peritoneal Dialysis. ELA, EMT, HPMCs, PD, PF, TGF-beta1
2022 Multi-tumor analysis of cancer-stroma interactomes of patient-derived xenografts unveils the unique homeostatic process in renal cell carcinomas. KIRC, PDX, TME
2021 Apelin Promotes Endothelial Progenitor Cell Angiogenesis in Rheumatoid Arthritis Disease via the miR-525-5p/Angiopoietin-1 Pathway. Ang-1, EPC, PKCalpha, PLCgamma, RA, RASFs
2021 APLN/APLNR Signaling Controls Key Pathological Parameters of Glioblastoma. APLNR, GBM
2021 APLN: A potential novel biomarker for cervical cancer. CR, GSEA, OS, PD, PR, SD
2021 Association between clinicopathological features of breast cancer with adipocytokine levels and oxidative stress markers before and after chemotherapy. RBP4, TAC
2021 Coregulation Analysis of Mechanistic Biomarkers in Autosomal Dominant Polycystic Kidney Disease. ADPKD, AGT, AVP, EGF, eGFR, ESKD, VEGFA
10  2021 Long non-coding RNA BACE1-AS plays an oncogenic role in hepatocellular carcinoma cells through miR-214-3p/APLN axis. BACE1-AS, HCC
11  2021 Maternal serum Apelin 13 and APLN gene promoter variant -1860T > C in preeclampsia. MAP, SGA
12  2021 Reduced Body Fat and Epididymal Adipose Apelin Expression Associated With Raspberry Ketone [4-(4-Hydroxyphenyl)-2-Butanone] Weight Gain Prevention in High-Fat-Diet Fed Mice. HFD, LFD, RK
13  2021 The Apelinergic System Immuno-Detection in the Abomasum and Duodenum of Sheep Grazing on Semi-Natural Pasture. APLNR, E p group, M F group
14  2021 The glycoprotein GP130 governs the surface presentation of the G protein-coupled receptor APLNR. GSCs
15  2020 Apelin Affects the Progression of Osteoarthritis by Regulating VEGF-Dependent Angiogenesis and miR-150-5p Expression in Human Synovial Fibroblasts. miR-150-5p, OA, OASFs, VEGF
16  2020 Apelin Controls Angiogenesis-Dependent Glioblastoma Growth. GBM, KO
17  2020 Apelin enhances IL-1beta expression in human synovial fibroblasts by inhibiting miR-144-3p through the PI3K and ERK pathways. IL-1beta, OA, OASFs
18  2020 Association of Apelin and Apelin Receptor Polymorphisms With the Risk of Comorbid Depression and Anxiety in Coronary Heart Disease Patients. APLNR, CHD
19  2020 Association of genetic defects in the apelin-AGTRL1 system with myocardial infarction risk in Han Chinese. CI, OR
20  2020 Circulating levels of Elabela and Apelin in the second and third trimesters of pregnancies with gestational diabetes mellitus. ELA, FPG, GDM, TC, TG
21  2020 Increased apelin receptor gene expression in the subfornical organ of spontaneously hypertensive rats. CVO, SFO, SHR, WKY
22  2020 Interaction of apelin, elabela and nitric oxide in schizophrenia patients. BMI, CI, ELA, NO, ROC, TG
23  2020 microRNA-182 Negatively Influences the Neuroprotective Effect of Apelin Against Neuronal Injury in Epilepsy. mGluR1, miRNA, mRNA, p-Akt, qRT-PCR
24  2020 The Apelin-Apelin Receptor Axis Triggers Cholangiocyte Proliferation and Liver Fibrosis During Mouse Models of Cholestasis. BDL, ERK, HIBEpiCs, HSC, NOX4, PSC, ROS, WT
25  2019 Apelin and chemerin as promising adipokines in children with type 1 diabetes mellitus. GFR, T1DM, TG
26  2019 Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. AAA, ACE2, Ang II, HFD, NEP, RAS, SMC
27  2019 Apelin system detection in the reproductive apparatus of ewes grazing on semi-natural pasture. APLNR
28  2019 APLN promotes hepatocellular carcinoma through activating PI3K/Akt pathway and is a druggable target. HCC, p-GSK3beta
29  2019 APLN/APJ pathway: The key regulator of macrophage functions. CVD
30  2019 Evaluation of elabela, apelin and nitric oxide findings in maternal blood of normal pregnant women, pregnant women with pre-eclampsia, severe pre-eclampsia and umbilical arteries and venules of newborns. ELA, NO
31  2019 Impaired cardiac performance, protein synthesis, and mitochondrial function in tumor-bearing mice. ---
32  2019 NAMPT, GRN, and SERPINE1 signature as predictor of disease progression and survival in gliomas. DFS, GBM, GRN, IL-6, LGG, mRNA, OS, PAI-1, RETN
33  2019 Role of Apelin in Glioblastoma Vascularization and Invasion after Anti-VEGF Therapy: What Is the Impact on the Immune System? GBM
34  2018 Apelin, the Devil Inside Brain Tumors. GSCs
35  2018 Transplantation of Human Amniotic Membrane over the Liver Surface Reduces Hepatic Fibrosis in a Cholestatic Model in Young Rats. AM, BDL, SS, TGFB1
36  2017 Apelin (APLN) regulates progesterone secretion and oocyte maturation in bovine ovarian cells. ---
37  2017 Bile duct ligature in young rats: A revisited animal model for biliary atresia. BDL, TGFB1
38  2017 Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan. CVD
39  2017 Identification and expression patterns of adipokine genes during adipocyte differentiation in the Tibetan goat (Capra hircus). FGF21, RETN
40  2017 Inhibition of Ubiquitin-conjugating Enzyme E2 May Activate the Degradation of Hypoxia-inducible Factors and, thus, Overcome Cellular Resistance to Radiation in Colorectal Cancer. CEMIP, HIF1alpha, UBE2
41  2017 The association between apelin gene polymorphism and coronary artery disease in young patients with acute obstructive coronary syndrome. ACS, CAD
42  2016 Apelin (APLN) and Apelin Receptor (APLNR) in Human Ovary: Expression, Signaling, and Regulation of Steroidogenesis in Primary Human Luteinized Granulosa Cells. APLNR, hGCs, HSD3B, IGF1, PCOS
43  2016 MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation. GPCR
44  2015 Genetic targeting of sprouting angiogenesis using Apln-CreER. ECs
45  2015 The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis. ELA
46  2014 Adipokines in gestational diabetes. A-FABP, RBP4, TNF-alpha
47  2014 Dysregulated microRNA-224/apelin axis associated with aggressive progression and poor prognosis in patients with prostate cancer. miR, PCa
48  2014 Sirt3 is essential for apelin-induced angiogenesis in post-myocardial infarction of diabetes. Ad-APLN, EPC, MI, SIRT3, Sirt3KO, STZ, WT
49  2013 Decreased apelin and apelin-receptor expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia. APLNR, BMPR2, CDH, EC, PH, SMCs
50  2013 Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia. Ang-1, Ang-2, LDI
51  2013 Genetic analysis of genes causing hypertension and stroke in spontaneously hypertensive rats. ADHD, AGT, CREM, Ephx2, FOSL1, LDLR, NTS, SHR, WKY
52  2013 Hepatocellular carcinoma cells cause different responses in expressions of cancer-promoting genes in different cancer-associated fibroblasts. CAF, FGF-2, FGF1, HCC, IL-6, LOXL2, MUC1, PDGFA, PGK1, VEGFA
53  2013 Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues. IR, MI
54  2013 Peritruncal coronary endothelial cells contribute to proximal coronary artery stems and their aortic orifices in the mouse heart. ---
55  2012 An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension. FGF-2, miRNA, PAECs, PAH
56  2012 APELIN promotes hematopoiesis from human embryonic stem cells. APLNR, EBs, hESCs
57  2012 Enhanced expressions of apelin on proliferative hepatic arterial capillaries in human cirrhotic liver. LCM, PCR
58  2011 Apelin is required for non-neovascular remodeling in the retina. RCS, RD1
59  2011 Gene expression in the adrenal glands of three spontaneously hypertensive rat substrains. BP, EPHX2, GJA1, IGF1R, KYNU, M-SHRSP, RGS2, SHR, UTS2, WKY
60  2007 Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. DFO