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Abbreviation : AT1
Long Form : angiotensin II type 1
No. Year Title Co-occurring Abbreviation
2021 Angiotensin II Type 1 receptor deficiency protects against the impairment of blood-brain barrier in a mouse model of traumatic brain injury. APP, AQP4, AT1-KO, BBB, ELISA, TBI, WB, ZO-1
2021 Angiotensin-converting enzyme 2, coronavirus disease 2019, and abdominal aortic aneurysms. AAA, ACE2, COVID-19, SARS-CoV-2
2021 Autoantibodies to Vasoregulative G-Protein-Coupled Receptors Correlate with Symptom Severity, Autonomic Dysfunction and Disability in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. AAb, AdR, GPCR, mAChR, ME/CFS, PEM
2021 Azilsartan Suppressed LPS-Induced Inflammation in U937 Macrophages through Suppressing Oxidative Stress and Inhibiting the TLR2/MyD88 Signal Pathway. DHE, ELISA, LDH, LPS, qRT-PCR, ROS
2021 Design, synthesis and antihypertensive evaluation of novel codrugs with combined angiotensin type 1 receptor antagonism and neprilysin inhibition. NEP, SHR
2021 Diosmetin attenuates metabolic syndrome and left ventricular alterations via the suppression of angiotensin II/AT1 receptor/gp91phox/p-NF-κB protein expression in high-fat diet fed rats. Ang II, HF, LV, MS, p-NF-kappaB
2021 EMA401, an angiotensin II type 2 receptor antagonist blocks visceral hypersensitivity and colonic hyperpermeability in rat model of irritable bowel syndrome. IBS
2021 Investigation of Receptor Heteromers Using NanoBRET Ligand Binding. BRET, Receptor-HIT
2021 Manifestation of renin angiotensin system modulation in traumatic brain injury. Ang II, RAS, TBI
10  2021 Pleiotropic Properties of Valsartan: Do They Result from the Antiglycooxidant Activity? Literature Review and In Vitro Study. AGE, AOPP, BSA, FRAP, GO, MGO, PC, TAC
11  2021 Renin-angiotensin system is involved in embryonic emergence of hematopoietic stem/progenitor cells. ACE, HSPCs, P-Sp, RAS
12  2021 Targeting the Angiotensin II Type 1 Receptor in Cerebrovascular Diseases: Biased Signaling Raises New Hopes. ---
13  2021 The Angiotensin II Type 1(AT1) Receptor and Cardiac Hypertrophy: Did We Have It Wrong All Along? ---
14  2021 Valsartan Prevented Neointimal Hyperplasia and Inhibited SRSF1 Expression and the TLR4-iNOS-ERK-AT1 Receptor Pathway in the Balloon-injured Rat Aorta. AT2, eNOS, ERK, iNOS, pERK, SRSF1, TLR4
15  2020 Angiotensin II Type 1 Receptor Expression in Renal Transplant Biopsies and Anti-AT1R Antibodies in Serum Indicates the Risk of Transplant Loss. AT1R, ELISA
16  2020 Cadmium exposure activates NADPH oxidase, renin-angiotensin system and cyclooxygenase 2 pathways in arteries, inducing hypertension and vascular damage. ACE, Cd, COX-2, MRA, SBP
17  2020 Comparison of clinical outcomes between angiotensin-converting-enzyme inhibitors and ARBs in patients with acute myocardial infarction with dyslipidemia after a successful stent implantation. ACEIs, aHR, AMI, CI, KAMIR, MACEs, re-MI, TLR, TVR
18  2020 Covid-19: the renin-angiotensin system imbalance hypothesis. ACE2, Ang II, COVID-19, RAS
19  2020 Design, synthesis and biological evaluation of novel fluoro-substituted benzimidazole derivatives with anti-hypertension activities. MBP
20  2020 Estrogen Deficiency and Colonic Function: Surgical Menopause and Sex Differences in Angiotensin and Dopamine Receptor Interaction. AT2, RAS
21  2020 Exposure to Traffic-Generated Pollutants Exacerbates the Expression of Factors Associated with the Pathophysiology of Alzheimer's Disease in Aged C57BL/6 Wild-Type Mice. AbetaPP, AD, AhR, CNS, FA, TJ
22  2020 GABA is a mediator of brain AT1 and AT2 receptor-mediated blood pressure responses. AT2, GABA, NTS, PVN, RVLM
23  2020 Intrarenal Renin Angiotensin System Imbalance During Postnatal Life Is Associated With Increased Microvascular Density in the Mature Kidney. Ang II, EBPfc, MatSep, RAS
24  2020 Losartan prevents mesenteric vascular bed alterations in high-fat diet fed rats. HF, HOMA-IR, PG, TX
25  2020 Pro-inflammatory cytokines in the paraventricular nucleus mediate the adipose afferent reflex in rats. AAR, Ang II, IL, iWAT, PICs, PVN, TNF, WAT
26  2020 Renal Nerve Deafferentation Attenuates the Fall in GFR during Intravenous Infusion of Furosemide in Anesthetized Rats. GFR, RVR
27  2020 Renin-Angiotensin-Aldosterone System and Migraine: A Systematic Review of Human Studies. RAS
28  2020 Role of the renin-angiotensin-aldosterone system in bone metabolism. ACE2, OPG, RAAS
29  2020 Study Design of the Phase 3 Sparsentan Versus Irbesartan (DUPLEX) Study in Patients With Focal Segmental Glomerulosclerosis. ETA, FSGS, UP/C
30  2020 Systematic characterization of AT1 receptor antagonists with label-free dynamic mass redistribution assays. DMR
31  2020 Targeted Delivery of Recombinant Heat Shock Protein 27 to Cardiomyocytes Promotes Recovery from Myocardial Infarction. HSPs, MI
32  2020 The renal antioxidative effect of losartan involves heat shock protein 70 in proximal tubule cells. NOX4, RAS, ROS, SHRs
33  2020 The role of the renin-angiotensin system in regulating endometrial neovascularization during the peri-implantation period: literature review and preliminary data. AT2, RAS
34  2020 Two protocols of aerobic exercise modulate the counter-regulatory axis of the renin-angiotensin system. ACE, Ang, HIIE, HRp, MICE, RAS
35  2019 Angiotensin II Type 1 Receptor Antagonist Azilsartan Restores Vascular Reactivity Through a Perivascular Adipose Tissue-Independent Mechanism in Rats with Metabolic Syndrome. MetS, PVAT, SHRSP.ZF
36  2019 Autoantibodies against AT1 Receptor Contribute to Vascular Aging and Endothelial Cell Senescence. CVD, PAD
37  2019 Candesartan inhibits inflammation through an angiotensin II type 1 receptor independent way in human embryonic kidney epithelial cells. IL-6, TGF-beta, TNF-alpha
38  2019 Effect of Shock Wave on Vascular Lesions in Diabetic Rats. eNOS, VEGF
39  2019 Image mean square displacement to study the lateral mobility of Angiotensin II type 1 and Endothelin 1 type A receptors on living cells. iMSD
40  2019 Isoflavone Ameliorated Oxidative Stress and Vascular Damages in Nicotine-Administrated Mice. ET-1, MMP
41  2019 Mitochondrial-Derived Peptide MOTS-c Attenuates Vascular Calcification and Secondary Myocardial Remodeling via Adenosine Monophosphate-Activated Protein Kinase Signaling Pathway. AMPK, ET-B, VC
42  2019 Molecular signaling of G-protein-coupled receptor in chronic heart failure and associated complications. ACE1, Ang II, GRK2
43  2019 Neuroprotective potential of azilsartan against cerebral ischemic injury: Possible involvement of mitochondrial mechanisms. ---
44  2019 Overexpression of the C-domain of angiotensin-converting enzyme reduces melanoma growth by stimulating M1 macrophage polarization. ACE, ROS, STAT1, TNF-alpha
45  2019 Perivascular Adipose Tissue-Enhanced Vasodilation in Metabolic Syndrome Rats by Apelin and N-Acetyl⁻l-Cysteine-Sensitive Factor(s). NAC, PVAT, SHRSP.ZF, wks
46  2019 Prenatal cold exposure causes hypertension in offspring by hyperactivity of the sympathetic nervous system. PVN
47  2019 Renal and cerebral RAS interaction contributes to diabetic kidney disease. RAS, STZ
48  2019 Role of angiotensin II type 1 (AT1) and type 2 (AT2) receptors in airway reactivity and inflammation in an allergic mouse model of asthma. Ang II, CON, MCh, OVA, SEN
49  2019 Sodium nitroprusside attenuates hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats through the inhibition of overexpression of AT1 receptor, cell cycle proteins, and c-Src/growth factor receptor signaling pathways. SHR, SNP, VSMC
50  2019 Telmisartan Inhibits Cell Proliferation and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inducing S-Phase Arrest In Vitro and In Vivo. ESCC, miRNAs
51  2019 The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats. CBF, GD
52  2019 The Milk Thistle (Silybum marianum) Compound Silibinin Inhibits Cardiomyogenesis of Embryonic Stem Cells by Interfering with Angiotensin II Signaling. Ang II, ES, JNK, MAPK
53  2018 Activation of voltage-gated sodium current and inhibition of erg-mediated potassium current caused by telmisartan, an antagonist of angiotensin II type-1 receptor, in HL-1 atrial cardiomyocytes. AMIO, APs, RAN, TEL
54  2018 Aging-related dysregulation in enteric dopamine and angiotensin system interactions: implications for gastrointestinal dysfunction in the elderly. AT2, RAS
55  2018 Angiotensin II, a stress-related neuropeptide in the CNS, facilitates micturition reflex in rats. ---
56  2018 Effects of chronic exposure to 12‰ saltwater on the endocrine physiology of juvenile American alligator (Alligator mississippiensis). ALDO, Ang II
57  2018 Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury. HHcy
58  2018 Influence of the AT1 Receptor Antagonists Telmisartan and Losartan on Reproduction and Offspring After Paternal Exposure to Ionizing Radiation. ---
59  2018 Influence of the interaction between Ac‑SDKP and Ang II on the pathogenesis and development of silicotic fibrosis. ACE, Ang II, Col, FN
60  2018 Inhibition of AT1 receptors by losartan affects myocardial slow force response in healthy but not in monocrotaline-treated young rats. RAS, SFR
61  2018 Liver Protective Effects of Renin-Angiotensin System Inhibition Have No Survival Benefits in Hepatocellular Carcinoma Induced By Repetitive Administration of Diethylnitrosamine in Mice. ACEIs, ARBs, DEN, FO, HCC, LO, PE, RAS, SO
62  2018 One-step methodology for the direct covalent capture of GPCRs from complex matrices onto solid surfaces based on the bioorthogonal reaction between haloalkane dehalogenase and chloroalkanes. AT2, beta2-AR, GPCRs, Halo
63  2018 Participation of hepatic alpha/beta-adrenoceptors and AT1 receptors in glucose release and portal hypertensive response induced by adrenaline or angiotensin II. ADR, AII, AR
64  2018 RAS in the Central Nervous System: Potential Role in Neuropsychiatric Disorders. ACE2, Ang, CNS, RAS
65  2018 The potential therapeutic use of renin-angiotensin system inhibitors in the treatment of inflammatory diseases. ACE, RAS
66  2018 The Role of Renin-Angiotensin-Aldosterone System and Its New Components in Arterial Stiffness and Vascular Aging. RAAS
67  2018 Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats. Ang II, Bcl, IL-1beta, NOX
68  2017 Activation of angiotensin II type 1 receptors increases D4 dopamine receptor expression in rat renal proximal tubule cells. Ang II, RPT, SHRs, WKY
69  2017 Angiotensin II activates CaV 1.2 Ca2+ channels through beta-arrestin2 and casein kinase 2 in mouse immature cardiomyocytes. Ang II, CK2alpha'beta, SFKs
70  2017 Angiotensin receptor blocker telmisartan inhibits cell proliferation and tumor growth of cholangiocarcinoma through cell cycle arrest. CCA, miRNAs, pEGFR
71  2017 AT1 expression in human urethral stricture tissue. Ang II, AT2
72  2017 AT1 Receptor Modulator Attenuates the Hypercholesterolemia-Induced Impairment of the Myocardial Ischemic Post-Conditioning Benefits. eNOS, HC, I/R, NC, PostC
73  2017 Comparison of Efficacy and Safety of Azilsartan and Olmesartan in Patients With Essential Hypertension. BP, Cr, DBP, PR, SBP, UA
74  2017 Dopamine modulates astroglial and microglial activity via glial renin-angiotensin system in cultures. AII, LPS, RAS
75  2017 Intrarenal Mas and AT1 receptors play a role in mediating the excretory actions of renal interstitial angiotensin-(1-7) infusion in anaesthetized rats. ---
76  2017 KLF 15 Works as an Early Anti-Fibrotic Transcriptional Regulator in Ang II-Induced Renal Fibrosis via Down-Regulation of CTGF Expression. Ang II, ChIP, Co-IP, CTGF, KLF15
77  2017 Low-sodium diet induces atherogenesis regardless of lowering blood pressure in hypertensive hyperlipidemic mice. BP, CML, HYD, IL, LOS, LS, NS, RAGE, TC, TG
78  2017 Molecular docking, 3D-QSAR and structural optimization on imidazo-pyridine derivatives dually targeting AT1 and PPARg. PPARgamma
79  2017 Monotherapy and Dual Combination Therapies Based on Olmesartan: A Comprehensive Strategy to Improve Blood Pressure Control. ---
80  2017 Pharmacological Profiles of a Highly Potent and Long-Acting Angiotensin II Receptor Antagonist, Fimasartan, in Rats and Dogs after Oral Administration. Ang II, p.o
81  2017 Physical Exercise and ACE2-Angiotensin-(1-7)-Mas Receptor Axis of the Renin Angiotensin System. ACE, ACE2, Ang II, RAS
82  2017 Protein disulfide isomerase regulates renal AT1 receptor function and blood pressure in rats. PDI
83  2017 Renin Angiotensin System and Cytokines in Chronic Kidney Disease: Clinical and Experimental Evidence. ACE, CKD, RAS
84  2017 Renin angiotensin system in liver diseases: Friend or foe? ACE, Ang, RAS
85  2017 Stat proteins as intracellular regulators of resistance to myocardial injury in the context of cardiac remodeling and targeting for therapy. ---
86  2017 Targeting multiple pathways reduces renal and cardiac fibrosis in rats with subtotal nephrectomy followed by coronary ligation. MAP
87  2017 Telmisartan inhibits hepatocellular carcinoma cell proliferation in vitro by inducing cell cycle arrest. AMPK, cCK18, HCC, miRNAs, mTOR
88  2017 The ACE-2/Ang1-7/Mas cascade enhances bone structure and metabolism following angiotensin-II type 1 receptor blockade. ACE-2, Ang 1-7, ARBs, OPG, RANKL, RAS
89  2017 The angiotensin II type 1 receptor antagonist telmisartan inhibits cell proliferation and tumor growth of esophageal adenocarcinoma via the AMPKalpha/mTOR pathway in vitro and in vivo. AMPK, EAC, pEGFR
90  2017 The Divergent Cardiovascular Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Type 1 Receptor Blockers in Adult Patients With Type 2 Diabetes Mellitus. ACEi's, Ang II, MI, RAAS
91  2016 Change of concept about the regulation of angiotensin II-induced monocyte chemoattractant protein-1 production in human endothelial cells. ANG, AT2, HUVECs, MCP-1, NF-kappaB
92  2016 Changes in cardiovascular responses to chemoreflex activation of rats recovered from protein restriction are not related to AT1 receptors. ---
94  2016 Disposition and metabolism of [(14)C] Sacubitril/Valsartan (formerly LCZ696) an angiotensin receptor neprilysin inhibitor, in healthy subjects. ARNI
95  2016 Experimental and DFT characterization, antioxidant and anticancer activities of a Cu(II)-irbesartan complex: structure-antihypertensive activity relationships in Cu(II)-sartan complexes. DFT, IRB
96  2016 Immunological risk assessment: The key to individualized immunosuppression after kidney transplantation. DSA, HLA
97  2016 Improved Insulin Sensitivity With Angiotensin Receptor Neprilysin Inhibition in Individuals With Obesity and Hypertension. NP
98  2016 Pharmacokinetic drug interaction study using fimasartan and rosuvastatin in healthy volunteers. CI, GMR
99  2016 Renin-Angiotensin-Aldosterone Signaling Inhibitors-Losartan, Enalapril, and Cardosten-Prevent Infarction-induced Heart Failure Development in Rats. ACEIs, MABP, RAAS, TPR, ULD
100  2016 Synergistic Inhibitory Effect of Rosuvastatin and Angiotensin II Type 2 Receptor Agonist on Vascular Remodeling. AT2, PCNA