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Abbreviation : ATRIP
Long Form : ATR-interacting protein
No. Year Title Co-occurring Abbreviation
2022 Chemical screen identifies shikonin as a broad DNA damage response inhibitor that enhances chemotherapy through inhibiting ATM and ATR. ATM, ATR, DDR
2022 Delineation of a minimal topoisomerase II binding protein1for regulated activation of ATR at DNA double-strand breaks. AAD, ATR, TOPBP1
2021 ATR activation is regulated by dimerization of ATR activating proteins. AADs, RPA
2021 NSMF promotes the replication stress-induced DNA damage response for genome maintenance. ATR, CDC5L, RF, RPA
2020 ATRIP protects progenitor cells against DNA damage in vivo. ATR
2019 The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function. A-NHEJ, ATM, ATR, DONSON, MRN, PCNA, RPA
2018 The interaction between ATRIP and MCM complex is essential for ATRIP chromatin loading and its phosphorylation in mantle cell lymphoma cells. GST, HA, IB, IP, MCL, MCM, MS, shRNA
2017 Cryo-EM structure of human ATR-ATRIP complex. EM
2017 Sirtuin 2 mutations in human cancers impair its function in genome maintenance. SIRT2
10  2016 ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA. ATR, RPA-ssDNA, SIRT2
11  2015 The SUMO (Small Ubiquitin-like Modifier) Ligase PIAS3 Primes ATR for Checkpoint Activation. CPT, PIAS, SUMO
12  2014 Gli1 protein regulates the S-phase checkpoint in tumor cells via Bid protein, and its inhibition sensitizes to DNA topoisomerase 1 inhibitors. ATR, CPT, RPA
13  2014 The PSO4 protein complex associates with replication protein A (RPA) and modulates the activation of ataxia telangiectasia-mutated and Rad3-related (ATR). ATR, RPA
14  2013 A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair. FA
15  2013 APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress. AP, ATM, Chk1, RPA
16  2013 Nek1 kinase associates with ATR-ATRIP and primes ATR for efficient DNA damage signaling. NIMA
17  2013 Structural basis for the BRCA1 BRCT interaction with the proteins ATRIP and BAAT1. BAAT1, BRCA1, DDR
18  2012 DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs. Chk1, DDR, Gadd45a, HIF1alpha, IR, IRES, MRE-11, PARP, Rfc2-5, XIAP
19  2012 Engagement of the ATR-dependent DNA damage response at the human papillomavirus 18 replication centers during the initial amplification. DDR, HPV, TopBP1
20  2012 Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome. MGS, SS
21  2011 BID binds to replication protein A and stimulates ATR function following replicative stress. Bid, HU, RPA
22  2010 A kinase-independent role for the Rad3(ATR)-Rad26(ATRIP) complex in recruitment of Tel1(ATM) to telomeres in fission yeast. ChIP
23  2010 Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling. aRPA, RPA
24  2009 The Arabidopsis ATRIP ortholog is required for a programmed response to replication inhibitors. HU, RPA
25  2009 TopBP1 and DNA polymerase-alpha directly recruit the 9-1-1 complex to stalled DNA replication forks. ATR, pol
26  2008 A role for E1B-AP5 in ATR signaling pathways during adenovirus infection. Ad, E1B-AP5, RPA32
27  2008 How ATR turns on: TopBP1 goes on ATRIP with ATR. ---
28  2008 TopBP1 activates ATR through ATRIP and a PIKK regulatory domain. ---
29  2007 Function of a conserved checkpoint recruitment domain in ATRIP proteins. CRD, RPA, TopBP1
30  2007 Perturbed gap-filling synthesis in nucleotide excision repair causes histone H2AX phosphorylation in human quiescent cells. ATR, NER, RPA
31  2007 Phosphorylation of ATR-interacting protein on Ser239 mediates an interaction with breast-ovarian cancer susceptibility 1 and checkpoint function. ATM, ATR, BRCA1
32  2006 ATRIP associates with replication protein A-coated ssDNA through multiple interactions. RPA
33  2006 Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities. ATR, MCM, PCNA
34  2006 Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling. NER, UV
35  2004 Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases. MCM
36  2001 ATR and ATRIP: partners in checkpoint signaling. ATM