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Abbreviation : C1-INH
Long Form : C1 inhibitor
No. Year Title Co-occurring Abbreviation
2022 Factor VII activating protease (FSAP) is not essential in the pathophysiology of angioedema in patients with C1 inhibitor deficiency. BK, FSAP, FSAP-alpha2AP, HAE, HK, PK, PPK
2021 Acquired angioedema in B cell lymphoproliferative disease: A retrospective case series. ---
2021 Analysis of cold activation of the contact system in hereditary angioedema with normal C1 inhibitor. FXII, HAE, HK
2021 C1 inhibitor mitigates peritoneal injury in zymosan-induced peritonitis. PD
2021 C1-Inhibitor: Structure, Functional Diversity and Therapeutic Development. HAE
2021 Clinical and genetic features of hereditary angioedema with and without C1-inhibitor (C1-INH) deficiency in Japan. ---
2021 Clinical Characteristics and Management of Angioedema Attacks in Polish Adult Patients with Hereditary Angioedema Due to C1-Inhibitor Deficiency. HAE
2021 COVID-19 and hereditary angioedema: Incidence, outcomes, and mechanistic implications. COVID-19, HAE, HAE-nl-C1INH
2021 Cut-off value of C1-inhibitor function for the diagnosis of hereditary angioedema due to C1-inhibitor deficiency. ---
10  2021 Evidence for a dominant-negative effect of a missense mutation in the SERPING1 gene responsible for hereditary angioedema type I. HAE
11  2021 HAE patient self-sampling for biomarker establishment. DBS, HAE, HAEKA, HKa
12  2021 Icatibant promotes patients' behavior modification associated with emergency room visits during an acute attack of hereditary angioedema. ER
13  2021 Inheritance Pattern of Hereditary Angioedema Indicates Mutation-Dependent Selective Effects During Early Embryonic Development. HAE
14  2021 Leveraging Genetics for Hereditary Angioedema: A Road Map to Precision Medicine. HAE
15  2021 Management of hereditary angioedema type I and homozygous MTHFR mutation during pregnancy. HAE, MTHFR
16  2021 Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex. Vag8
17  2021 Periodic Severe Angioedema without Exogenous Hormone Exposure. HAE
18  2021 Preventive Treatment of Hereditary Angioedema: A Review of Phase III Clinical Trial Data for Subcutaneous C1 Inhibitor and Relevance for Patient Management. COMPACT, HAE, HRQoL, LTP, OLE
19  2021 Psychology and hereditary angioedema: A systematic review. HAE, KWs, SERPING1
20  2021 Recognition and Management of Hereditary Angioedema: Best Practices for Dermatologists. HAE, LTP
21  2021 Safety and efficacy of C1-inhibitor in traumatic brain injury (CIAO@TBI): study protocol for a randomized, placebo-controlled, multi-center trial. GOSE, ICP, TBI, TIL
22  2021 Sugar Matters: Improving In Vivo Clearance Rate of Highly Glycosylated Recombinant Plasma Proteins for Therapeutic Use. CHO
23  2021 Survey of actual conditions of erythema marginatum as a prodromal symptom in Japanese patients with hereditary angioedema. EM, HAE, HAEnC1-INH
24  2021 The Challenges in the Follow-Up and Treatment of Brazilian Children with Hereditary Angioedema. HAE
25  2021 The Expanding Spectrum of Mutations in Hereditary Angioedema. ANGPT1, HAE, HS3ST6, SERPING1
26  2021 The Global Registry for Hereditary Angioedema due to C1-Inhibitor Deficiency. HAE
27  2021 The importance of recognizing and managing a rare form of angioedema: hereditary angioedema due to C1-inhibitor deficiency. HAE, mAb, QoL, s.c
28  2021 The role of C1 inhibitor and complement as acute phase reactants: are we missing the diagnosis of hereditary angioedema? CRP, HAE, URTI
29  2021 Unnecessary Abdominal Surgeries in Attacks of Hereditary Angioedema with Normal C1 Inhibitor. HAE
30  2020 Advances in Hereditary Angioedema: The Prevention of Angioedema Attacks With Subcutaneous C1-Inhibitor Replacement Therapy. HAE
31  2020 Alpha-2-macroglobulin from circulating exosome-like vesicles is increased in women with preterm pregnancies. A2M, NTA, PPROM, PTL, WB
32  2020 Bradykinin and oxidative stress in patients with hereditary angioedema due to C1 inhibitor deficiency. AGEs, AOPPs, HAE, PBMCs, ROS
33  2020 Clinical features of genetically characterized types of hereditary angioedema with normal C1 inhibitor: a systematic review of qualitative evidence. HAE, HAE-ANGPT1, HAE-KNG1, HAE-PLG
34  2020 Experience with Intravenous Plasma-Derived C1-Inhibitor in Pregnant Women with Hereditary Angioedema: A Systematic Literature Review. HAE
35  2020 Expression and production of the SERPING1-encoded endogenous complement regulator C1-inhibitor in multiple cohorts of tuberculosis patients. LTBI, TB
36  2020 Hereditary Angioedema with and Without C1-Inhibitor Deficiency in Postmenopausal Women. HAE
37  2020 Hereditary angioedema: Epidemiology and burden of disease. HAE, QoL
38  2020 Hereditary angioedema: Pathophysiology (HAE type I, HAE type II, and HAE nC1-INH). FXII, HAE
39  2020 Hereditary C1 inhibitor deficiency associated with systemic lupus erythematosus. SLE
40  2020 Identification of the minimum region of Bordetella pertussis Vag8 required for interaction with C1 inhibitor. Vag8
41  2020 Long-Term Efficacy of Subcutaneous C1 Inhibitor in Pediatric Patients with Hereditary Angioedema. HAE, OLE, s.c
42  2020 Long-term safety and efficacy of subcutaneous C1-inhibitor in older patients with hereditary angioedema. AEs, HAE
43  2020 Management of hereditary angioedema in Japan: Focus on icatibant for the treatment of acute attacks. HAE
44  2020 Measurement of Bradykinin Formation and Degradation in Blood Plasma: Relevance for Acquired Angioedema Associated With Angiotensin Converting Enzyme Inhibition and for Hereditary Angioedema Due to Factor XII or Plasminogen Gene Variants. ACE, AE, BK, FXII, HAE, iBK, tPA
45  2020 Orthognathic Surgery in Hereditary Angioedema With Normal C1 Inhibitor: A Clinical Response to Concentrated C1 Inhibitor Against Angioedema Attack. HAE
46  2020 Patterns of C1-Inhibitor/Plasma Serine Protease Complexes in Healthy Humans and in Hereditary Angioedema Patients. HAE
47  2020 Recognition and Differential Diagnosis of Hereditary Angioedema in the Emergency Department. AE, ED, HAE
48  2020 Short-term prophylaxis in patients with angioedema due to C1-inhibitor deficiency undergoing dental procedures: An observational study. LTP, STP
49  2020 The Influence of ACE Inhibition on C1-Inhibitor: A Biomarker for ACE Inhibitor-Induced Angioedema? ACE
50  2020 The Panorama of Primary Angioedema in the Brazilian Population. PA
51  2020 Treatment of patients with hereditary angioedema with the c.988A>G (p.Lys330Glu) variant in the plasminogen gene. HAE, SD
53  2019 A Case of Acquired Angioedema with Low C1 Inhibitor (C1-INH) Associated with Splenic Marginal Zone Lymphoma. ---
54  2019 A randomized trial of human C1 inhibitor prophylaxis in children with hereditary angioedema. BOP, EQ-VAS, HRQoL, NNA
55  2019 Acquired C1-inhibitor deficiency presenting with nephrotic syndrome. ---
56  2019 Anesthetic Management of a Patient With Hereditary Angioedema for Oral Surgery. HAE
57  2019 Angioedema due to acquired C1-inhibitor deficiency: spectrum and treatment with C1-inhibitor concentrate. pdC1-INH, SD
58  2019 C1 Inhibitor Activity and Angioedema Attacks in Patients with Hereditary Angioedema. HAE
59  2019 Cerebrospinal fluid complement system biomarkers in demyelinating disease. CIS, CSF, FB, FH, FI, MS, NMOSD, TCC
60  2019 Contradictory to its effects on thrombin, C1-inhibitor reduces plasmin generation in the presence of thrombomodulin. PG, TG, TM
61  2019 Hereditary Angio-Oedema for Dermatologists. HAE
62  2019 Hereditary angioedema in Austria: prevalence and regional peculiarities. HAE
63  2019 Hereditary Angioedema-Associated Acute Pancreatitis in C1-Inhibitor Deficient and Normal C1-Inhibitor Patients: Case Reports and Literature Review. HAE
64  2019 Hereditary angioedema: Screening of first-degree blood relatives and earlier diagnosis. HAE, SD
65  2019 Indirect comparison of intravenous vs. subcutaneous C1-inhibitor placebo-controlled trials for routine prevention of hereditary angioedema attacks. HAE, OR, SC
66  2019 iTRAQ analysis of liver immune-related proteins from darkbarbel catfish (Pelteobagrus vachelli) infected with Edwardsiella ictaluri. ESC, iTRAQ, MHC class I, PSME1, SRP54
67  2019 Knockdown of circulating C1 inhibitor induces neurovascular impairment, glial cell activation, neuroinflammation, and behavioral deficits. ASO, BBB, KKS, WT
68  2019 Lanadelumab to treat hereditary angioedema. HAE
69  2019 Low Levels of IgM and IgA Recognizing Acetylated C1-Inhibitor Peptides Are Associated with Systemic Lupus Erythematosus in Taiwanese Women. Ac, HCs, IgM, OR, SLE
70  2019 Management of patients with hereditary angio-oedema in dental, oral, and maxillofacial surgery: a review. HEA
71  2019 Manufacturing of plasma-derived C1-inhibitor concentrate for treatment of patients with hereditary angioedema. HAE
72  2019 Melkersson-Rosenthal syndrome: a case report of a rare disease with overlapping features. MRS
73  2019 Modeling Cost-Effectiveness of On-Demand Treatment for Hereditary Angioedema Attacks. HAE, pd, QALY, rh
74  2019 Prophylaxis of Acute Attacks with a Novel Short-term Protocol in Hereditary Angioedema Patients Requiring Periodontal Treatment. CAL, FMBS, FMPS, FMS, PD, SRP
75  2019 Review of the Manitoba cohort of patients with hereditary angioedema with normal C1 inhibitor. ---
76  2019 SERPING1 exon 3 splicing variants using alternative acceptor splice sites. HAE, ss
77  2019 SERPING1 mutation update: Mutation spectrum and C1 Inhibitor phenotypes. ---
78  2019 Serum complexes between C1INH and C1INH autoantibodies for the diagnosis of acquired angioedema. antiC1INHAbs, C1INH-antiC1INHAb, ELISA, Ig
79  2019 Update on C1 Esterase Inhibitor in Human Solid Organ Transplantation. AMR, IRI
80  2018 Acquired and hereditary forms of recurrent angioedema: Update of treatment. HAE
81  2018 C1-esterase inhibitor (Cinryze) use in the treatment of pediatric hereditary angioedema. HAE
82  2018 Classical Pathway of Complement Activation: Longitudinal Associations of C1q and C1-INH With Cardiovascular Outcomes: The CODAM Study (Cohort on Diabetes and Atherosclerosis Maastricht)-Brief Report. CVD
83  2018 Complement Activation During Ischemia/Reperfusion Injury Induces Pericyte-to-Myofibroblast Transdifferentiation Regulating Peritubular Capillary Lumen Reduction Through pERK Signaling. I/R, PMT
84  2018 Complement C3 and C4, but not their regulators or activated products, are associated with incident metabolic syndrome: the CODAM study. FD, FH, OR
85  2018 Complement system biomarkers in epilepsy. AED, CLU, CRP, ELISA, FB, FH, TCC
86  2018 Dominant-negative SERPING1 variants cause intracellular retention of C1 inhibitor in hereditary angioedema. ER, HAE
87  2018 Effects of C1 inhibitor on endothelial cell activation in a rat hind limb ischemia-reperfusion injury model. HS, I/R
88  2018 First Analysis of SERPING1 Gene in Patients with Hereditary Angioedema in Colombia Reveals Two Genotypic Variants in a Highly Symptomatic Individual. HAE
89  2018 Gene mapping strategy for Alu elements rearrangements: Detection of new large deletions in the SERPING1 gene causing hereditary angioedema in Brazilian families. EQT, HAE
90  2018 Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles. A1AT, CHO
91  2018 Hereditary angioedema with C1 inhibitor (C1-INH) deficit: the strength of recognition (51 cases). HAE
92  2018 Identification of human plasma C1 inhibitor as a target protein for staphylococcal superantigen-like protein 5 (SSL5). GST, MMP-9, PSGL-1, SSL5, SSLs
93  2018 Quantification of human C1 esterase inhibitor protein using an automated turbidimetric immunoassay. HAE, UAE
94  2018 Recombinant human C1 esterase inhibitor (Conestat alfa) for prophylaxis to prevent attacks in adult and adolescent patients with hereditary angioedema. HAE, rhC1-INH
95  2018 Serial change of C1 inhibitor in patients with sepsis: a prospective observational study. ---
96  2018 The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. BMDMs, oxPOS, RPE
97  2018 The hereditary angioedema syndromes. HAE, WT
98  2018 The role of complement components C1q, MBL and C1 inhibitor in pathogenesis of endometriosis. MBL, PF
99  2018 Threshold-stimulated kallikrein activity distinguishes bradykinin- from histamine-mediated angioedema. HAE, INHA
100  2018 Transcriptional profiling, molecular cloning, and functional analysis of C1 inhibitor, the main regulator of the complement system in black rockfish, Sebastes schlegelii. rSsC1inh