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Abbreviation : CB
Long Form : cathepsin B
No. Year Title Co-occurring Abbreviation
2021 Diagnostic usefulness of selected proteases and acute phase factors in patients with colorectal adenocarcinoma. ATA, LASA, LE, ROC, TSA
2019 Effect of orthodontic forces on levels of enzymes in gingival crevicular fluid (GCF): A systematic review. ACP, ALP, AST, betaG, GCF, LDH, MMPs, TRAP
2019 Near-Infrared Fluorescent Activated Polymeric Probe for Imaging Intraluminal Colorectal Cancer Tumors. CRC, NIRF, s.c
2018 Acrolein-induced autophagy-dependent apoptosis via activation of the lysosomal-mitochondrial pathway in EAhy926 cells. CA
2017 Role of Cathepsin B as a Marker of Malignant Transformation in Oral Lichen Planus: An Immunohistochemical Study. OLP, OSCC
2017 [Salidroside improves pulmonary fibrosis by down-regulation of cathepsin B and NF-kappaBp65 in rats]. ---
2015 Cathepsin B Imaging to Predict Quality of Engineered Cartilage. NIRF
2015 Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity. CD, CL
2015 Development of a New Antileishmanial Aziridine-2,3-Dicarboxylate-Based Inhibitor with High Selectivity for Parasite Cysteine Proteases. CAC1, CL, CPs
10  2015 Fabrication of doxorubicin-loaded ellipsoid micelle based on diblock copolymer with a linkage of enzyme-cleavable peptide. DOX, vc
11  2014 Detection of esophageal squamous cell carcinoma by cathepsin B activity in nude mice. ESCC, NIRF
12  2014 Role of cathepsin B in regulating migration and invasion of fibroblast-like synoviocytes into inflamed tissue from patients with rheumatoid arthritis. FAK, FLS, IHC, JNK, MAPKs, MMP, OA, qPCR, RA, RNAi, siRNA
13  2014 Treatment with CA-074Me, a Cathepsin B inhibitor, reduces lung interstitial inflammation and fibrosis in a rat model of polymyositis. CVB1, ILD, PM/DM
14  2013 Administration of cathepsin B inhibitor CA-074Me reduces inflammation and apoptosis in polymyositis. CVB1, FCA, PM, TNF-alpha
15  2013 Interleukin-10 down-regulates cathepsin B expression in fetal rat alveolar type II cells exposed to hyperoxia. CBI, FATIIC, LDH, rIL-10
16  2013 Non-invasive optical imaging of cathepsin B with activatable fluorogenic nanoprobes in various metastatic models. CNPs
17  2011 Cathepsin B is activated as an executive protease in fetal rat alveolar type II cells exposed to hyperoxia. FATIIC
18  2011 Effect of shRNA mediated down-regulation of Annexin A2 on biological behavior of human lung adencarcinoma cells A549. MMP-2
19  2010 Cathepsin B-dependent motor neuron death after nerve injury in the adult mouse. HGN, LC3
20  2010 Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells. MMP-9, uPAR
21  2010 [Clinical significance of cathepsin B expressions in cervical cancer in tissues]. CIN, ISCC
22  2009 Cathepsin B release after imatinib-mediated lysosomal membrane permeabilization triggers BCR-ABL cleavage and elimination of chronic myelogenous leukemia cells. CML, LMP
23  2009 Chapter 4. Peptidases of trematodes. CE, CL
24  2009 Endostatin expression in neurons during the early stage of cerebral ischemia is associated with neuronal apoptotic cell death in adult hypertensive rat model of stroke. AMC, dMCAO, ES, IR
25  2009 Involvement of cathepsin B in the processing and secretion of interleukin-1beta in chromogranin A-stimulated microglia. CgA, IL-1beta
26  2008 Cathepsin B expression in prostate cancer of native Japanese and Japanese-American patients: an immunohistochemical study. CCD, J-A, NJ, PCa, PSA, RP, SA, TMA
27  2008 Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity. CD, DLB, LB, PD
28  2008 Participation of cathepsin B in emodin-induced apoptosis in HK-2 Cells. SD, TRAs
29  2008 Possible involvement of cathepsin B released by microglia in methylmercury-induced cerebellar pathological changes in the adult rat. ---
30  2008 [Prognostic implications of biologic markers in intracranial meningiomas: 120 cases]. CD, CL, CysC, Re, Rp, STB, TK
31  2007 6-Hydroxydopamine induces cystatin C-mediated cysteine protease suppression and cathepsin D activation. CC, CD, LS, PA, PARP
32  2007 A novel method for imaging in vivo degradation of poly(L-glutamic acid), a biodegradable drug carrier. NIRF
33  2007 Cathepsin B expression is similar in African-American and Caucasian prostate cancer patients. BPH, PCa, SA
34  2007 Cathepsin B is involved in the apoptosis intrinsic pathway induced by Bacillus Calmette-Guerin in transitional cancer cell lines. BCG, CA
35  2006 Enhanced cystatin C and lysosomal protease expression following 6-hydroxydopamine exposure. CD, ROS
36  2006 Quantitative evaluation of each catalytic subsite of cathepsin B for inhibitory activity based on inhibitory activity-binding mode relationship of epoxysuccinyl inhibitors by X-ray crystal structure analyses of complexes. ---
37  2006 Total and lipid-bound plasma sialic acid as diagnostic markers in colorectal cancer patients: correlation with cathepsin B expression in progression to Dukes stage. TSA
38  2006 Urinary activities of cathepsin B, N-acetyl-beta-D-glucosaminidase, and albuminuria in patients with type 2 diabetes mellitus. NAG
39  2006 [Cathepsin B expression and malignances and angiogenesis in gliomas]. MVD, SABC
40  2005 Activity of enzymes with different subcellular localization in the blood plasma of patients with aortic aneurysm. AST, CD, ChE, CL, GGTP, LDH
41  2005 Cathepsin B mediates TRAIL-induced apoptosis in oral cancer cells. OSCC
42  2005 Cathepsin B promotes both motility and invasiveness of oral carcinoma cells. ---
43  2005 Cathepsins B and D activity and activity ratios in normal ovaries, benign ovarian neoplasms, and epithelial ovarian cancer. CB/CD
44  2005 Expression of cathepsin B and microvascular density increases with higher grade of astrocytomas. BM, ECM, MVD
45  2005 Significance and prognostic value of lysosomal enzyme activities measured in surgically operated adenocarcinomas of the gastroesophageal junction and squamous cell carcinomas of the lower third of esophagus. AMAN, DPPI, GEJ, LTE
46  2004 Cathepsin B and cathepsin D expression in the progression of colorectal adenoma to carcinoma. CD
47  2004 Differential susceptibility of metastatic and primary oral cancer cells to TRAIL-induced apoptosis. OC
48  2004 [Cathepsin B and pro-drug activation]. ---
49  2004 [Serum stefin A in patients with type 2 diabetes]. NAG
50  2003 High expression of cathepsin B in transitional bladder carcinoma correlates with tumor invasion. kD, TCC
51  2003 [Studies on proliferation inhibition and anti-invasion of retinoic acid and 18beta-glycyrrhetinic acid in highly metastasized human lung cancer cell line]. GA, RA
52  2003 [Study on anti-invasive effect and apoptosis induction of pentacyclic triterpenoid in human lung cancer cells]. AO/EB, GA, GL, OA, UA
53  2001 Cathepsin B on invasion and metastasis of gastric carcinoma. ---
54  2001 Cathepsin B/cystatin C complex levels in sera from patients with lung and colorectal cancer. CC, CV
55  2001 Expression of cathepsins B, L, S, and D by gastric epithelial cells implicates them as antigen presenting cells in local immune responses. APC
56  2001 Plasma membrane association of cathepsin B in human prostate cancer: biochemical and immunogold electron microscopic analysis. BPH, CPIs
57  2001 Ratio of cathepsin B to stefin A identifies heterogeneity within Gleason histologic scores for human prostate cancer. BPH, PSA
58  2001 Synovial tissue protease gene expression and joint erosions in early rheumatoid arthritis. CL, MMP-1, mRNA, PsA, RA
59  2000 Cathepsin B levels in urine from bladder cancer patients. Md, TCC
60  2000 Cathepsin-B fusion proteins misroute secretory protein partners such as the proprotein convertase PC2-7B2 complex toward the lysosomal degradation pathways. ---
61  2000 Expression of cathepsin proteinases by mouse trophoblast in vivo and in vitro. ---
62  2000 Lysosomal activity of pulmonary alveolar macrophages in acute experimental pancreatitis in rats with reference to positive PAF-antagonist (BN 52021) effect. AP, BALF, NAH, PAM's
63  2000 Prognostic impact of cathepsin B and matrix metalloproteinase-9 in pulmonary adenocarcinomas by immunohistochemical study. MMP-9
64  2000 Prognostic significance of DNA ploidy, S-phase fraction, and tissue levels of aspartic, cysteine, and serine proteases in operable gastric carcinoma. CD, CL, GCs, SPF, TNM, uPA
65  2000 Selection of a dominant negative retinoblastoma protein (RB) inhibiting satellite myoblast differentiation implies an indirect interaction between MyoD and RB. Rb
66  2000 The relationship of cathepsin B and stefin A mRNA localization identifies a potentially aggressive variant of human prostate cancer within a Gleason histologic score. BPH
67  1999 Cathepsin B activity and protein levels in thyroid carcinoma, Graves' disease, and multinodular goiters. FC, GD, MNG, PC, Tg, TSH
68  1999 Collagenase, cathepsin B and cathepsin L gene expression in the synovial membrane of patients with early inflammatory arthritis. CL, RA, SM
69  1999 Cysteine proteases and cysteine protease inhibitors in non-small cell lung cancer. CC, CL, CnC, LAC, SFA, SFB, SqCLC
70  1999 High levels of cathepsin B predict poor outcome in patients with breast cancer. ER, uPA
71  1999 Regulation of cathepsin B activity by cysteine and related thiols. N-AcCys, RSH
72  1998 Codistribution of procathepsin B and mature cathepsin B forms in human prostate tumors detected by confocal and immunofluorescence microscopy. FITC, IgG, proCB
73  1998 Effect of protein kinase modulators on the regulation of cathepsin B activity in THP-1 human monocytic leukemia cells. LPS, PKA, PKC, PMA
74  1998 Interferon-c induces cathepsin B expression in a human macrophage-like cell line by increasing both transcription and mRNA stability. IFN-c
75  1998 Modulation of interferon gamma induced increases in cathepsin B in THP-1 cells by adrenergic agonists and antagonists. IFN, ISO, PMA
76  1998 Proteases and their inhibitors in human brain tumours: a review. CL, MMPs
77  1997 Cathepsin B and Cathepsin D Expression in Follicular Adenomas and Carcinomas of the Thyroid Gland. CD, EICs, FAs, MICs
78  1997 Cathepsin B, thiols and cysteine protease inhibitors in squamous-cell lung cancer. CC, SqCLC
79  1997 Endotoxin induces increased intracellular cathepsin B activity in THP-1 cells. IFN-gamma, LPS
80  1997 Immunohistochemical study of constituents other than beta-protein in canine senile plaques and cerebral amyloid angiopathy. ACT, APOE, CC, CD, HSP70, SPs, UBQ
81  1997 Interferon-gamma induced increases in intracellular cathepsin B activity in THP-1 cells are dependent on RNA transcription. IFN-gamma
82  1997 Regulation of cathepsin B activity by modulators of arachidonic acid metabolism in human monocytes. IFN-gamma, LPS
83  1996 Gamma interferon induced increases in intracellular cathepsin B activity in PMA primed THP-1 cells are blocked by inhibitors of protein kinase C. DAG, IFN-gamma, PKA, PKC, PMA
84  1996 Marked increases in cathepsin B and L activities distinguish papillary carcinoma of the thyroid from normal thyroid or thyroid with non-neoplastic disease. CL, HT, MNG, Tg
85  1996 Preferential MyoD homodimer formation demonstrated by a general method of dominant negative mutation employing fusion with a lysosomal protease. ---
86  1996 Relationship between morphological diversity and AgNORs or cathepsin B expression in colorectal cancers. NORs
87  1996 [Cathepsin B-like substance in the monitoring of chemically induced primary cholangiocarcinoma in swine]. CEA, GL, PLAP
88  1995 Age-related changes in cellular localization and enzymatic activities of cathepsins B, L and D in the rat trigeminal ganglion neuron. TG
89  1995 Cathepsin B in angiogenesis of human prostate: an immunohistochemical and immunoelectron microscopic analysis. BPH, PIN
90  1995 Clinical relevance of cathepsin B-like enzyme activity and cysteine proteinase inhibitor in melanocytic tumours. CPI, MM, PM, PN
91  1995 Expression of pancreatic trypsinogen/trypsin and cathepsin B in human cholangiocarcinomas and hepatocellular carcinomas. CCs, HCCs, PT
92  1995 Immunohistochemical localization of cathepsin B in neoplastic human prostate. ECM
93  1995 Immunolocalization of cathepsin B in human glioma: implications for tumor invasion and angiogenesis. ---
94  1995 Increased cathepsin B activity in multiple sclerosis brain. ---
95  1995 Microglial cathepsin B: an immunological examination of cellular and secreted species. ---
96  1994 Imbalance between cathepsin-B and cysteine proteinase-inhibitors is of prognostic-significance in human lung-cancer. CPI's
97  1994 Immunohistochemical distributions of cathepsin B and basement membrane antigens in human lung adenocarcinoma: association with invasion and metastasis. BMs, CIV, LM
98  1994 Increased cathepsin B activity in peripheral blood mononuclear cells of multiple sclerosis patients. AD, CD, MS, NA, NC, OND, PBMCs
99  1994 Prognostic value of increased lung tumor tissue cathepsin B. ---
100  1994 Transcriptional regulation of cathepsin B expression in B16 melanomas of varying metastatic potential. ---