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Abbreviation : CLK
Long Form : CDC-like kinases
No. Year Title Co-occurring Abbreviation
2021 A Crosstalk Between Dual-Specific Phosphatases and Dual-Specific Protein Kinases Can Be A Potential Therapeutic Target for Anti-cancer Therapy. CDK, DUSPs, DYRKs, MAPKs, MKPs, mTOR, mTORC1, PI3K, PTKs, PTPs
2021 Oncogenic dysregulation of pre-mRNA processing by protein kinases: challenges and therapeutic opportunities. CDK, SRPK
2019 The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models. CRC, SRSF
2017 A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore. CDKs, SAR
2017 Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma. DYRK
2015 Synthesis of desaza analogues of annomontine and canthin-4-one alkaloids. ---
2014 Modulation of p53beta and p53gamma expression by regulating the alternative splicing of TP53 gene modifies cellular response. ---
2013 Proteasome-mediated proteolysis of SRSF5 splicing factor intriguingly co-occurs with SRSF5 mRNA upregulation during late erythroid differentiation. ---
2013 The highly conserved LAMMER/CLK2 protein kinases prevent germ cell overproliferation in Drosophila. ---
10  2011 Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy. ---
11  2011 Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk). Dyrk
12  2010 Regulation and differential role of the tissue factor isoforms in cardiovascular biology. DNA topo I, FL, SR, SRPK, TF
13  2009 Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk). ---
14  2009 Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation. MAPKs, SR
15  2006 Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets. TF
16  2002 Disassembly of interchromatin granule clusters alters the coordination of transcription and pre-mRNA splicing. IGCs, SR
17  2001 Molecular characterization of a cDNA encoding functional human CLK4 kinase and localization to chromosome 5q35 [correction of 4q35]. SR