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[Related PubMed/MEDLINE]
Total Number of Papers: 870
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| Abbreviation |
: COX-1 |
| Long Form |
: cyclooxygenase-1 |
|
| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2023 |
FTIR Characterization of Sulfated Polysaccharides Obtained from Macrocystis integrifolia Algae and Verification of Their Antiangiogenic and Immunomodulatory Potency In Vitro and In Vivo. |
CAM, COX-2, IgE, NF-kappaB, NOS2, OVA |
| 2 |
2023 |
In silico and in vitro anti-inflammatory study of phenolic compounds isolated from Eucalyptus maculata resin. |
EME |
| 3 |
2022 |
Apolipoprotein E*Ɛ2 carriers exhibit high aspirin-treated platelet reactivity and low cardiovascular risk during long-term aspirin treatment. |
APOE, CV |
| 4 |
2022 |
Benzoylpaeoniflorin Activates Anti-Inflammatory Mechanisms to Mitigate Sepsis in Cell-Culture and Mouse Sepsis Models. |
BPF, CLP, HUVECs, IL, iNOS, LPS, MAPKs, NF-kappaB, qPCR, TNF, XBJI |
| 5 |
2022 |
Comparison of Absolute Expression and Turnover Number of COX-1 and COX-2 in Human and Rodent Cells and Tissues. |
COX-2, SCC |
| 6 |
2022 |
Design, synthesis, biological assessment and in silico ADME prediction of new 2-(4-(methylsulfonyl) phenyl) benzimidazoles as selective cyclooxygenase-2 inhibitors. |
COX-2 |
| 7 |
2022 |
Diindolylmethane ameliorates platelet aggregation and thrombosis: In silico, in vitro, and in vivo studies. |
ADP, cAMP, DIM, GPVI, I3C, P2Y12, PGE2, ROS, TTO, TXB2 |
| 8 |
2022 |
Endoplasmic-reticulum-stress-induced lipotoxicity in human kidney epithelial cells. |
Cer, cPLA2, ER, GRP78, PGE2, PUFA, S1P, SM, TM, TUDCA |
| 9 |
2022 |
In vitro, in vivo and in silico evaluation of the anti-inflammatory potential of Hyssopus officinalis L. subsp. aristatus (Godr.) Nyman (Lamiaceae). |
COX-2, NSAID, RA |
| 10 |
2022 |
Low-Dose NSAIDs Efficacy in Orthopedic Applications. |
COX-2, NSAIDs |
| 11 |
2022 |
Mechanism of Traditional Tibetan Medicine Grubthobrildkr Alleviated Gastric Ulcer Induced by Acute Systemic Hypoxia in Rats. |
COX-2, ET-1, GAS, GTB, MTL, PGE2, PLA2, UHPLC-Q-Orbitrap MS |
| 12 |
2022 |
MiodesinTM Positively Modulates the Immune Response in Endometrial and Vaginal Cells. |
IL-1beta, LPS, MMP-2, NF-kappaB, PLA2, TNF-alpha, VEGF |
| 13 |
2022 |
Nonsteroidal Anti-inflammatory Drugs Are Not Associated With Increased Bleeding in Blunt Solid Organ Injury. |
--- |
| 14 |
2022 |
Pyrroloquinoline Quinone Disodium (PQQ2Na) Has an NLRP Inflammasome-Induced Caspase-1 Release Influence in UVB-Irradiated but Not ATP-Treated Human Keratinocytes but Has No Influence in Increasing Skin Cell Mitochondrial Biogenesis in Either Human Keratinocytes or Fibroblasts. |
NHDF, NHEKs, NLRP, SDHA |
| 15 |
2022 |
Signaling Pathways Mediating Bradykinin-Induced Contraction in Murine and Human Detrusor Muscle. |
BK, KO, TP |
| 16 |
2022 |
Study on the inhibition of inflammation by the cyclooxygenase-2 (COX-2)/prostaglandin E2 (PGE2) pathway and the promotion of wound healing of oral ulcer of Yangyin Shengji powder after chemotherapy. |
COX-2, EGF, EGFR, ELISA, GSH-Px, HE, IL-6, MDA, PGE2, RT-PCR, SOD, TNF-alpha, Tr |
| 17 |
2022 |
Synthesis of Sugar and Nucleoside Analogs and Evaluation of Their Anticancer and Analgesic Potentials. |
CCK-8, COX-2 |
| 18 |
2022 |
The Hypertensive Effect of Amphotericin B-Containing Liposomes (Abelcet) in Mice: Dissecting the Roles of C3a and C5a Anaphylatoxins, Macrophages and Thromboxane. |
CVF, HR, MABP, TP |
| 19 |
2022 |
Whole-Body PET Imaging in Humans Shows That 11C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs. |
COX-2 |
| 20 |
2021 |
Adipose-derived stem cells inhibit dermal fibroblast growth and induce apoptosis in keloids through the arachidonic acid-derived cyclooxygenase-2/prostaglandin E2 cascade by paracrine. |
AA, ADSCs, Bcl-2, EdU, KFBs, PGE2 |
| 21 |
2021 |
Aspirin Actions in Treatment of NSAID-Exacerbated Respiratory Disease. |
NSAID |
| 22 |
2021 |
Aspirin effects on platelet gene expression are associated with a paradoxical, increase in platelet function. |
--- |
| 23 |
2021 |
Chemical Profiles and Pharmacological Properties with in Silico Studies on Elatostema papillosum Wedd. |
NF |
| 24 |
2021 |
Choline Glycerophospholipid-Derived Prostaglandins Attenuate TNFalpha Gene Expression in Macrophages via a cPLA2alpha/COX-1 Pathway. |
AA, PI |
| 25 |
2021 |
Development of a DHA-Losartan hybrid as a potent inhibitor of multiple pathway-induced platelet aggregation. |
CVDs, PAF, PAR-1, RAS |
| 26 |
2021 |
Development of Fluorescence Imaging Probes for Labeling COX-1 in Live Ovarian Cancer Cells. |
--- |
| 27 |
2021 |
Diagnostic Value of Serum Markers Combined with TVCDS in Ovarian Cancer Patients Treated with Bushen Yiqi Quyu Prescription. |
HE4, OC, TVCDS |
| 28 |
2021 |
Discovery of Natural Product Inspired 3-Phenyl-1H-isochromen-1-ones as Highly Potent Antioxidant and Antiplatelet Agents: Design, Synthesis, Biological Evaluation, SAR and In Silico Studies. |
AA, DPPH |
| 29 |
2021 |
Dynamics of Cyclooxygenase-1 Positive Microglia/Macrophage in the Retina of Pathological Model Mice as a Biomarker of the Retinal Inflammatory Diseases. |
EAU, LPS |
| 30 |
2021 |
Electroacupuncture attenuates vascular hyporeactivity in a rat model of portal hypertension induced by bile duct ligation. |
6-keto-PGF1 alpha, BDL, EA, NOS, PHT, PKCalpha, TGFbetaR, TNF-alpha, VEGF |
| 31 |
2021 |
Evaluation of analgesic and anti-inflammatory activities and molecular docking analysis of steroidal lactones from Datura stramonium L. |
iNOS, LOX-1, LPS, NF-kappaB |
| 32 |
2021 |
Exercise-Induced Modulation of Angiotensin II Responses in Femoral Veins From 2-Kidney-1-Clip Hypertensive Rats. |
2K1C, Ang II, COX-2, ET-1, ETA, NO |
| 33 |
2021 |
Experimental Periodontal Disease Triggers Coronary Endothelial Dysfunction in Middle-Aged Rats: Preventive Effect of a Prebiotic beta-Glucan. |
eNOS, IL-1beta, TNF-alpha |
| 34 |
2021 |
Gastroprotective Effect of Myricetin on Ethanol-Induced Acute Gastric Injury in Rats. |
MDA, NF-kappaB, PGE2, SOD |
| 35 |
2021 |
Genotoxic effects of Dukhan: A smoke bath from the wood of Acacia seyal used traditionally by Sudanese women. |
--- |
| 36 |
2021 |
Green synthesis of selenium based N-heterocyclic carbene compounds; structural, in-vitro anticancer and molecular docking studies. |
HeLa, HIF, NHC |
| 37 |
2021 |
Hepatoprotective Effect of Lactobacillus plantarum HFY09 on Ethanol-Induced Liver Injury in Mice. |
ADH, ALDH, BW, CAT, ERK, GSH-Px, HAase, IL-10, JNK, LP-HFY09, MDA, NADPH, PC III, SOD, TC, TG, TNF |
| 38 |
2021 |
Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling. |
HNC, IR, JNK, NSAID, PGE2, SOCE |
| 39 |
2021 |
Influence of Lipid Excipients on Platelet Function and the Pharmacodynamic Effects of Aspirin. |
--- |
| 40 |
2021 |
Inhibitory Mechanisms of Lusianthridin on Human Platelet Aggregation. |
ADP, COX-2 |
| 41 |
2021 |
Lipid metabolism is a novel and practical source of potential targets for antiviral discovery against porcine parvovirus. |
DKGalpha, iPLA2beta, LDs, LPAATtheta, PGE2, PI3K, PKC, PLCgamma2, PPV |
| 42 |
2021 |
Modulation of the PGE2-Mediated Pathway in the Eclosion Blocking Effect of Flumethrin and Terpenoid Subfraction Isolated from Artemesia nilagirica in Rhipicephalus annulatus. |
PGE2, PGES, Vg |
| 43 |
2021 |
Non-steroidal anti-inflammatory drugs dampen the cytokine and antibody response to SARS-CoV-2 infection. |
ACE2, COVID-19, COX-2, NSAIDs, PGs, SARS-CoV-2 |
| 44 |
2021 |
Nonsteroidal anti-inflammatory drugs hypersensitivity in chronic spontaneous urticaria in the light of its pathogenesis. |
CSU, NECD |
| 45 |
2021 |
Oleuropein attenuates the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-perturbing effects on pancreatic beta-cells. |
PGE2, TCDD |
| 46 |
2021 |
Olmesartan niosomes ameliorates the Indomethacin-induced gastric ulcer in rats: Insights on MAPK and Nrf2/HO-1 signaling pathway. |
HO-1, IL-6, IND, Nrf2, OLM, OLM-NIO, p38 MAPK, PGE2, TNF-alpha |
| 47 |
2021 |
Panax Notoginseng Saponin Attenuates Gastric Mucosal Epithelial Cell Injury Induced by Dual Antiplatelet Drugs through COX and PI3K/Akt/ VEGF-GSK-3beta-RhoA Network Pathway. |
6-keto-PGF1 alpha, COX-2, DA, ELISA, GSK-3beta, p-Akt, p-PI3K, PGE2, PI3K, PNS, RhoA, VEGF |
| 48 |
2021 |
Platelet ACKR3/CXCR7 favors antiplatelet lipids over anatherothrombotic lipidome and regulates thromboinflammation. |
12-HETrE, 12-LOX, CAD, DGLA |
| 49 |
2021 |
Profiling oxylipins released from human platelets activated through the GPVI collagen receptor. |
12-LOX, GPVI |
| 50 |
2021 |
Proliferation of bovine endometrial epithelial cells is promoted by prostaglandin E2-PTGER2 signaling through cell cycle regulation. |
bEEC, COX-2, EGF, PCNA, PGE2, PTGER2 |
| 51 |
2021 |
Selective intra-arterial brain cooling induces cerebral protection against ischemia/reperfusion injury through SENP1-Sirt3 signaling. |
I/R, IDH2, OGD, SI-AC, SOD2 |
| 52 |
2021 |
Structure-based screening for the discovery of 1,2,4-oxadiazoles as promising hits for the development of new anti-inflammatory agents interfering with eicosanoid biosynthesis pathways. |
5-LO, mPGES-1 |
| 53 |
2021 |
Synthesis of [18F]PS13 and Evaluation as a PET Radioligand for Cyclooxygenase-1 in Monkey. |
PET |
| 54 |
2021 |
Synthesis, Inhibitory Activity, and In Silico Modeling of Selective COX-1 Inhibitors with a Quinazoline Core. |
--- |
| 55 |
2021 |
The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity. |
COX-2, EGF, EOBT, MMP-2, MPO, VEGF |
| 56 |
2021 |
The Role of Celecoxib as a Potential Inhibitor in the Treatment of Inflammatory Diseases - A Review. |
COX, COX-2, NSAIDs |
| 57 |
2020 |
6-Methoxyflavanone abates cisplatin-induced neuropathic pain apropos anti-inflammatory mechanisms: A behavioral and molecular simulation study. |
6-MeOF, COX-2 |
| 58 |
2020 |
A randomized double-blind trial of 3 aspirin regimens to optimize antiplatelet therapy in essential thrombocythemia. |
ET, sTXB2, TXM |
| 59 |
2020 |
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid. |
AA, CVDs, mof-spacer-AA, mof-spacer-mof, NSAIDs, SI |
| 60 |
2020 |
Analysis of the Activity and Expression of Cyclooxygenases COX1 and COX2 in THP-1 Monocytes and Macrophages Cultured with BiodentineTM Silicate Cement. |
COX-2, PGE2 |
| 61 |
2020 |
Anti-inflammatory effect of methoxyflavonoids from Chiliadenus montanus (Jasonia Montana) growing in Egypt. |
5-LOX, COX-2, IL-1beta, LPS, NF-kappaB, TNF-alpha |
| 62 |
2020 |
Association between High On-Aspirin Platelet Reactivity and Reduced Superoxide Dismutase Activity in Patients Affected by Type 2 Diabetes Mellitus or Primary Hypercholesterolemia. |
HC, SOD, T2DM |
| 63 |
2020 |
Biological Evaluation of Naproxen-Dehydrodipeptide Conjugates with Self-Hydrogelation Capacity as Dual LOX/COX Inhibitors. |
COX-2, LOX, MRI, NSAID, SPIONs |
| 64 |
2020 |
Cassia sieberiana DC. leaves modulate LPS-induced inflammatory response in THP-1cells and inhibit eicosanoid-metabolizing enzymes. |
5-LOX, IL-6, TNF-alpha |
| 65 |
2020 |
Chrysin Modulates Genes Related to Inflammation, Tissue Remodeling, and Cell Proliferation in the Gastric Ulcer Healing. |
EGF |
| 66 |
2020 |
Cyclooxgenase-2 is induced by SARS-CoV-2 infection but does not affect viral entry or replication. |
ACE2, COVID-19, COX-2, NSAIDs, PGs, SARS-CoV-2 |
| 67 |
2020 |
Cyclooxygenase 1 (COX1) as an indicator of sperm quality in humans. |
--- |
| 68 |
2020 |
Cyclooxygenase-1 mediates neuroinflammation and neurotoxicity in a mouse model of retinitis pigmentosa. |
PGE2, RP |
| 69 |
2020 |
Cytotoxicity evaluation of ketoprofen found in pharmaceutical wastewater on HEK 293 cell growth and metabolism. |
--- |
| 70 |
2020 |
Design, synthesis and biological assessment of new selective COX-2 inhibitors including methyl sulfonyl moiety. |
NSAIDs |
| 71 |
2020 |
Design, Synthesis and Evaluation of 3-Substituted Coumarin Derivatives as Anti-inflammatory Agents. |
SARs |
| 72 |
2020 |
Effects of Benidipine Hydrochloride on Ischemia Reperfusion Injury of Rat Brain. |
I/R, MDA, SOD |
| 73 |
2020 |
Endogenous cannabinoids may regulate chronic inflammation in aspirin-exacerbated respiratory disease. |
AERD, PG |
| 74 |
2020 |
Enhanced conditioning of adverse memories in the mouse modified swim test is associated with neuroinflammatory changes - Effects that are susceptible to antidepressants. |
GSK-3, IL-1beta, TNF |
| 75 |
2020 |
Evaluation of Anti-Inflammatory Components of Guizhi Fuling Capsule, an Ancient Chinese Herbal Formula, in Human Umbilical Vein Endothelial Cells. |
GFC, HUVECs, LPS |
| 76 |
2020 |
First-in-human evaluation of [11C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain. |
--- |
| 77 |
2020 |
Gastroprotective effects of the nonsaponin fraction of Korean Red Ginseng through cyclooxygenase-1 upregulation. |
NSF |
| 78 |
2020 |
Glycogen Synthase Kinase-3beta Mediates Proinflammatory Cytokine Secretion and Adipogenesis in Orbital Fibroblasts from Patients with Graves' Orbitopathy. |
GO, GSK-3beta, ICAM-1, MCP-1, NF, PPARgamma, RT-PCR |
| 79 |
2020 |
Impact of antipyretics on acute asthma exacerbation during respiratory infection-A nationwide population-based study. |
AE, NSAIDs |
| 80 |
2020 |
In Vivo Anti-Inflammation Potential of Aster koraiensis Extract for Dry Eye Syndrome by the Protection of Ocular Surface. |
AKE, COX-2, DES, ER, TG |
| 81 |
2020 |
Increased PUFA levels in kidney epithelial cells in the course of diclofenac toxicity. |
cPLA2, DCL, PGE2, PUFAs, TQ |
| 82 |
2020 |
Intake of aspirin prior to metamizole does not completely prevent high on treatment platelet reactivity. |
AA, HTPR, IA, LTA |
| 83 |
2020 |
Kisspeptin/GnRH1 system in Leydig cells of horse (Equus caballus): Presence and function. |
Kiss, PGF2 alpha |
| 84 |
2020 |
Mechanistic evaluation of gastro-protective effects of KangFuXinYe on indomethacin-induced gastric damage in rats. |
COX-2, EGF, IL-6, KFX, PGE2 |
| 85 |
2020 |
Outcomes from Experimental Testing of Nonsteroidal Anti-Inflammatory Drug (NSAID) Administration during the Transition Period of Dairy Cows. |
COX-2, NSAID |
| 86 |
2020 |
Phytosterols demonstrate selective inhibition of COX-2: In-vivo and in-silico studies of Nicotiana tabacum. |
NSAIDs, NTPI, vHTS |
| 87 |
2020 |
Polymyxin B prevents the development of adjuvant arthritis via modulation of TLR/Cox-2 signaling pathway. |
hs-CRP, NF-kappaB, RA, TGF-1beta, TLR, TNF-alpha |
| 88 |
2020 |
Prostaglandin E2 stimulates the epithelial sodium channel (ENaC) in cultured mouse cortical collecting duct cells in an autocrine manner. |
CCD, ENaC, EP4, PGE2 |
| 89 |
2020 |
Prostaglandin F2alpha-PTGFR signaling promotes proliferation of endometrial epithelial cells of cattle through cell cycle regulation. |
CDKs, COX-2, EGF, PCNA, PGF2 alpha |
| 90 |
2020 |
Repurposing 11C-PS13 for PET Imaging of Cyclooxygenase-1 in Ovarian Cancer Xenograft Mouse Models. |
OvCa |
| 91 |
2020 |
Solidagenone from Solidago chilensis Meyen inhibits skin inflammation in experimental models. |
AA, COX-2, IL-6, MPO, NAG, NO, SOL, TNF-alpha |
| 92 |
2020 |
Yunnan Baiyao diminishes lipopolysaccharide-induced inflammation in osteoclasts. |
AA, LPS, MAPK, YNBY |
| 93 |
2020 |
[Study about neural inflammation in mental illness and development of drug screening using in vitro models of disease]. |
PGE2, TLR |
| 94 |
2019 |
Altered Lipid Metabolism in Blood Mononuclear Cells of Psoriatic Patients Indicates Differential Changes in Psoriasis Vulgaris and Psoriatic Arthritis. |
13-HODE, 15-HETE, 4-HNE, 8-iso-PGF2alpha, COX-2, LTB4, PGE1, TXB2 |
| 95 |
2019 |
Analgesic and Anti-Inflammatory Activities of Quercetin-3-methoxy-4'-glucosyl-7-glucoside Isolated from Indian Medicinal Plant Melothria heterophylla. |
--- |
| 96 |
2019 |
Analgesic and anti-inflammatory effects and molecular mechanisms of Kadsura heteroclita stems, an anti-arthritic Chinese Tujia ethnomedicinal herb. |
COX-2, IL-1beta, IL-6, iNOS, KHS, RA |
| 97 |
2019 |
Anti-inflammatory Compound Shows Therapeutic Safety and Efficacy against Flavivirus Infection. |
DENV, ZIKV |
| 98 |
2019 |
Antitussive and Anti-inflammatory Dual-active Agents Developed from Natural Product Lead Compound 1-Methylhydantoin. |
COX-2 |
| 99 |
2019 |
Are All Oral COX-2 Selective Inhibitors the Same? A Consideration of Celecoxib, Etoricoxib, and Diclofenac. |
BP, COX-2, CV, GI, NSAIDs |
| 100 |
2019 |
Aspirin & clopidogrel non-responsiveness & its association with genetic polymorphisms in patients with myocardial infarction. |
CI, DAPT, MI, OR, TXB2 |
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