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Abbreviation : Cx32
Long Form : connexin32
No. Year Title Co-occurring Abbreviation
2021 AAV1.NT-3 gene therapy for X-linked Charcot-Marie-Tooth neuropathy type 1. GJB1, KO, NT-3
2021 AAV9-mediated Schwann cell-targeted gene therapy rescues a model of demyelinating neuropathy. GJ, MPZ
2021 Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson's disease. alpha-syn, CNS, PD, Tg
2021 Connexin32 activates necroptosis through Src-mediated inhibition of caspase 8 in hepatocellular carcinoma. HCC
2021 Cysteine residues in the C-terminal tail of connexin32 regulate its trafficking. CT, Cxs, GJs
2021 Dysregulation of Blood-Brain Barrier and Exacerbated Inflammatory Response in Cx47-Deficient Mice after Induction of EAE. BSCB, dpi, EAE, GJs, KO, MS
2021 Investigating oligodendrocyte connexins: Heteromeric interactions between Cx32 and mutant or wild-type forms of Cx47 do not contribute to or modulate gap junction function. PMLD1
2020 A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats. DMN, GST-P, HFD, IR, MCDD, NASH, WT
2020 Characterization of three connexin32 genes and their role in inflammation-induced ATP release in the Japanese flounder Paralichthys olivaceus. eATP
10  2020 Connexin 32 deficiency protects the liver against ischemia/reperfusion injury. I/R, OLT
11  2020 Effects of Connexin 32-Mediated Lung Inflammation Resolution During Liver Ischemia Reperfusion. HIR, IL-6, MMP-12
12  2020 Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation. ALD, AMP
13  2020 Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway. FN, ICAM-1, NOX4, ROS
14  2019 A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration. EMC
15  2019 Binding of alpha-synuclein oligomers to Cx32 facilitates protein uptake and transfer in neurons and oligodendrocytes. MSA, PD
16  2019 Cx32 exerts anti-apoptotic and pro-tumor effects via the epidermal growth factor receptor pathway in hepatocellular carcinoma. Co-IP, EGFR, GJs, HCC, SN, TNM
17  2019 Cx32 mediates cisplatin resistance in human ovarian cancer cells by affecting drug efflux transporter expression and activating the EGFR‑Akt pathway. EGFR, ERCC1
18  2019 Gene replacement therapy after neuropathy onset provides therapeutic benefit in a model of CMT1X. NEFL
19  2019 Inhibition of ubiquitin‑specific protease14 promotes connexin32 internalization and counteracts cisplatin cytotoxicity in human ovarian cancer cells. Cx, DUB, GJIC, UPS, USP14
20  2019 Role of Connexin-Based Gap Junction Channels in Communication of Myelin Sheath in Schwann Cells. CMT, GJB1, GJCs, PNS, SCs, SLI
21  2018 Acetylation of C-terminal lysines modulates protein turnover and stability of Connexin-32. N2a
22  2018 Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress apoptosis signaling pathway in ischemia reperfusion-induced acute kidney injury. AKI, ERS, I/R, ROS
23  2018 Crosstalk Between Connexin32 and Mitochondrial Apoptotic Signaling Pathway Plays a Pivotal Role in Renal Ischemia Reperfusion-Induced Acute Kidney Injury. AKI, GJ, HR, IR, ROS
24  2018 Effects of Helicobacter pylori on the expression levels of GATA-3 and connexin 32 and the GJIC function in gastric epithelial cells and their association by promoter analysis. GATA3, GJIC, H. pylori, siRNA, SLDT
25  2018 Hepatic connexin 32 associates with nonalcoholic fatty liver disease severity. NAFLD
26  2018 Intrathecal gene therapy in mouse models expressing CMT1X mutations. GJB1, KO, WT
27  2018 Regulation of Connexin32 by ephrin receptors and T-cell protein-tyrosine phosphatase. CT, Eph
28  2018 Regulatory role of oligodendrocyte gap junctions in inflammatory demyelination. BSCB, Cx47, EAE, GJs, KO, MS
29  2018 What's the Function of Connexin 32 in the Peripheral Nervous System? PNS, SC
30  2017 Cx32 hemichannel opening by cytosolic Ca2+ is inhibited by the R220X mutation that causes Charcot-Marie-Tooth disease. cAMP
31  2017 Cx32 inhibits TNFalpha-induced extrinsic apoptosis with and without EGFR suppression. 18alpha-GA, CHX, Dox, EGFR, GJIC, TNF-alpha, TRAIL
32  2017 Cx32 suppresses extrinsic apoptosis in human cervical cancer cells via the NF‑kappaB signalling pathway. GJ, GJIC, TNF-alpha, TRAIL
33  2017 Genomic instability induced in distant progeny of bystander cells depends on the connexins expressed in the irradiated cells. Cx26, Cx43
34  2017 Golgi-retained Cx32 mutants interfere with gene addition therapy for CMT1X. ---
35  2017 PBX1 attributes as a determinant of connexin 32 downregulation in Helicobacter pylori-related gastric carcinogenesis. GC, H. pylori, NGM, RT-PCR, TFs
36  2017 Substitution impact of highly conserved arginine residue at position 75 in GJB1 gene in association with X-linked Charcot-Marie-tooth disease: A computational study. CMT, CMTX1
37  2017 Tramadol attenuates the sensitivity of glioblastoma to temozolomide through the suppression of Cx43‑mediated gap junction intercellular communication. Cx, Cx43, TMZ
38  2016 Aberrant trafficking of a Leu89Pro connexin32 mutant associated with X-linked dominant Charcot-Marie-Tooth disease. ---
39  2016 Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells. GJIC, hESC-Heps, MAPK
40  2016 Connexin32‑mediated antitumor effects of suicide gene therapy against hepatocellular carcinoma: In vitro and in vivo anticancer activity. ATRA
41  2016 Gap Junctions Contribute to the Regulation of Walking-Like Activity in the Adult Mudpuppy (Necturus Maculatus). Cx36, Cx37, Cx43
42  2016 Increased Cx32 expression in spinal cord TrkB oligodendrocytes following peripheral axon injury. BDNF, CST, IML, OL
43  2016 Structural studies of N-terminal mutants of Connexin 26 and Connexin 32 using (1)H NMR spectroscopy. ---
44  2016 Systemic inflammation disrupts oligodendrocyte gap junctions and induces ER stress in a model of CNS manifestations of X-linked Charcot-Marie-Tooth disease. GJ, KO, LPS, WT
45  2015 A start codon CMT1X mutation associated with transient encephalomyelitis causes complete loss of Cx32. CNS
46  2015 Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis. Dusp1, EtOH, GST-P, HCC, Tg, WT
47  2015 CSF-1-activated macrophages are target-directed and essential mediators of Schwann cell dedifferentiation and dysfunction in Cx32-deficient mice. CSF
48  2015 Inhibition of gap junctions relieves the hepatotoxicity of TNF-alpha. GJ
49  2015 Intraneural GJB1 gene delivery improves nerve pathology in a model of X-linked Charcot-Marie-Tooth disease. EGFP, KO, MPZ
50  2015 Localization of connexin 32 in spontaneous liver lesions of mice. ---
51  2015 Oxaliplatin-induced neurotoxicity is mediated through gap junction channels and hemichannels and can be prevented by octanol. CAP, GJ, KO, OIN
52  2014 Cell differentiation mediated by co-culture of human umbilical cord blood stem cells with murine hepatic cells. AML12, CK8, RT-PCR, SOX17
53  2014 Connexin32 regulates hepatoma cell metastasis and proliferation via the p53 and Akt pathways. HCC
54  2014 Connexins and cyclooxygenase-2 crosstalk in the expression of radiation-induced bystander effects. COX-2, Cx, Cx26
55  2014 Connexins, gap junctions and peripheral neuropathy. GJs
56  2014 Dexmedetomidine protects against apoptosis induced by hypoxia/reoxygenation through the inhibition of gap junctions in NRK-52E cells. DEX, GJ, GJIC, I/R
57  2014 Down-regulation of connexin43 and connexin32 in keratocystic odontogenic tumours: potential association with clinical features. Bcl-2, Cx43, KCOT, LC3, OM, PCNA, qPCR
58  2014 Endothelial connexin 32 regulates tissue factor expression induced by inflammatory stimulation and direct cell-cell interaction with activated cells. EC, GJ, HUVECs, ICAM-1, TF, TNF-alpha
59  2014 Four novel connexin 32 mutations in X-linked Charcot-Marie-Tooth disease. Phenotypic variability and central nervous system involvement. CMT, CNS, GJB1
60  2014 Gap junction enhances phototoxicity of photodynamic therapy agent 2-[1-hexyloxyethyl]-2-devinylpyropheophorbide-a (HPPH). GJ, HPPH, PDT, ROS
61  2014 Gene expression profiling studies in regenerating nerves in a mouse model for CMT1X: uninjured Cx32-knockout peripheral nerves display expression profile of injured wild type nerves. Cx32KO, dpi, WT
62  2014 GJB1-associated X-linked Charcot-Marie-Tooth disease, a disorder affecting the central and peripheral nervous systems. CMT
63  2014 Oligodendrocyte gap junction loss and disconnection from reactive astrocytes in multiple sclerosis gray matter. MS, NAGM
64  2014 Propofol attenuated acute kidney injury after orthotopic liver transplantation via inhibiting gap junction composed of connexin 32. AKI, AOLT
65  2014 Tetramethylpyrazine suppresses transient oxygen-glucose deprivation-induced connexin32 expression and cell apoptosis via the ERK1/2 and p38 MAPK pathway in cultured hippocampal neurons. OGD, TMP
66  2013 Connexin47 protein phosphorylation and stability in oligodendrocytes depend on expression of Connexin43 protein in astrocytes. DKO
67  2013 Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells. BM, LSK
68  2013 Endothelial connexin32 enhances angiogenesis by positively regulating tube formation and cell migration. HUVECs
69  2013 Hereditary motor and sensory neuropathy (HMSN) type X1 in an Argentinean family reveals independent GJB1/Cx32 mutations at the identical nucleotide position. HMSN
70  2013 Lipid membrane association of myelin proteins and peptide segments studied by oriented and synchrotron radiation circular dichroism spectroscopy. MBP, OCD, SRCD
71  2013 Role of connexin 32 hemichannels in the release of ATP from peripheral nerves. ATP, SCs
72  2013 Spinal astrocyte gap junctions contribute to oxaliplatin-induced mechanical hypersensitivity. CBX, Cx36, Cx43, GFAP
73  2013 The oligodendroglial precursor cell line Oli-neu represents a cell culture system to examine functional expression of the mouse gap junction gene connexin29 (Cx29). Cx29, Cx47
74  2013 X-linked Charcot-Marie-Tooth disease. GJ
75  2012 Age-dependent carcinogenic susceptibility in rat liver is related to potential of gap junctional intercellular communication. DEN, GJIC, GST-P, WT
76  2012 Background lesions during a 24-month observation period in connexin 32-deficient mice. ---
77  2012 Characterization of the structure and intermolecular interactions between the connexin 32 carboxyl-terminal domain and the protein partners synapse-associated protein 97 and calmodulin. CaM, CT, SAP97
78  2012 Connexin 43 hemichannels contribute to cytoplasmic Ca2+ oscillations by providing a bimodal Ca2+-dependent Ca2+ entry pathway. BK
79  2012 Disruption of oligodendrocyte gap junctions in experimental autoimmune encephalomyelitis. dpi, EAE, GJs, MS, NAWM
80  2012 Expression of connexin 32 and connexin 43 in acute myeloid leukemia and their roles in proliferation. AML, Cx43, Cxs
81  2012 Functional requirement for a highly conserved charged residue at position 75 in the gap junction protein connexin 32. CMT
82  2012 Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure. DILI
83  2012 Genetic epidemiology of Charcot-Marie-Tooth disease. CMT, CMT1, CMT2, dHMN, DSS, EGR2, Mfn2, MPZ, PMP22, SIMPLE
84  2012 How do mutations in GJB1 cause X-linked Charcot-Marie-Tooth disease? GJ
85  2012 Human cell responses to ionizing radiation are differentially affected by the expressed connexins. Cx26
86  2011 Connexin 32 is involved in mitosis. ---
87  2011 Connexin-26 is a key factor mediating gemcitabine bystander effect. Cx26, GJIC
88  2011 Connexin32 can restore hearing in connexin26 deficient mice. Cx26
89  2011 Gap junction disorders of myelinating cells. GJs
90  2011 Gap junctions in inherited human disorders of the central nervous system. ODDD, PMLD
91  2011 In vitro motility of liver connexin vesicles along microtubules utilizes kinesin motors. ---
92  2011 Increased Cell-Cell Coupling Increases Infarct Size and Does not Decrease Incidence of Ventricular Tachycardia in Mice. Cx43, VT, WT
93  2011 Peripheral lymphangiogenesis in mice depends on ectodermal connexin-26 (Gjb2). Cx26KICx32
94  2011 Propofol depresses the cytotoxicity of X-ray irradiation through inhibition of gap junctions. GJ
95  2011 X-linked dominant Charcot-Marie-Tooth disease with connexin 32 (Cx32) mutations in Koreans. EC2
96  2010 Cytoplasmic accumulation of connexin32 expands cancer stem cell population in human HuH7 hepatoma cells by enhancing its self-renewal. CSC, Dox, HCC, SP
97  2010 Genetic epidemiology of Charcot-Marie-Tooth in the general population. CMT, EGR2, MCV, Mfn2, MPZ, PMP22, SIMPLE
98  2010 MFN2 point mutations occur in 3.4% of Charcot-Marie-Tooth families. An investigation of 232 Norwegian CMT families. CMT2, dHMN, Mfn2, MPZ, PMP22
99  2010 Mild form of Charcot-Marie-Tooth type 1X disease caused by a novel Cys179Gly mutation in the GJB1/Cx32 gene. CMT1X
100  2010 Molecular mechanisms of gap junction mutations in myelinating cells. ---