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[Related PubMed/MEDLINE] Total Number of Papers: 439
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Abbreviation |
: CysLTs |
Long Form |
: cysteinyl leukotrienes |
|
No. |
Year |
Title |
Co-occurring Abbreviation |
1 |
2022 |
A Dual Role for Cysteinyl Leukotriene Receptors in the Pathogenesis of Corneal Infection. |
--- |
2 |
2022 |
Five-lipoxygenase-activating protein-mediated CYLD attenuation is a candidate driver in hepatic malignant lesion. |
5-LO, AAI, CYLD, FLAP, HCC |
3 |
2022 |
Leukotriene D4 accelerates antigen-mediated mast cell responses via the cysteinyl leukotriene 1 receptor. |
BMMCs, MCs |
4 |
2022 |
Mechanisms by which dupilumab normalizes eicosanoid metabolism and restores aspirin-tolerance in AERD: A hypothesis. |
AERD, PGE2 |
5 |
2022 |
Neuroprotective effects of CysLTR antagonist on Streptococcus pneumoniae-induced meningitis in rats. |
SP |
6 |
2021 |
Emerging role of cysteinyl LTs in cancer. |
--- |
7 |
2021 |
Exercise-induced alterations in phospholipid hydrolysis, airway surfactant, and eicosanoids and their role in airway hyperresponsiveness in asthma. |
AHR, BAL, EIB, PGD2 |
8 |
2021 |
Oxidative biomarkers of exhaled breath condensate in adults exposed to traffic-related air pollution: a case-control study. |
EBC, IQR, TRAP |
9 |
2021 |
Persistent Eosinophilic Inflammation in Adult Asthmatics with High Serum and Urine Levels of Leukotriene E4. |
AERD, ATA, LTRA |
10 |
2021 |
Protectins PCTR1 and PD1 Reduce Viral Load and Lung Inflammation During Respiratory Syncytial Virus Infection in Mice. |
PCTR1, PD1, RSV, SPMs |
11 |
2021 |
The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch. |
CysLT2R, DRG, LTC4 |
12 |
2021 |
Transcriptome Analysis Identifies Doublesex and Mab-3 Related Transcription Factor (DMRT3) in Nasal Polyp Epithelial Cells of Patients Suffering from Non-Steroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease (AERD). |
AERD, AERD, DMRT3, ELISA, IHC |
13 |
2021 |
Tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation. |
DCs, IL-25, LTC4 |
14 |
2020 |
12-Oxo-10-glutathionyl-5,8,14-eicosatrienoic acid (TOG10), a novel glutathione-containing eicosanoid generated via the 12-lipoxygenase pathway in human platelets. |
AA, CTRs, DHA, EXs, GST, LTC4S, MCTRs, pt12-LOX |
15 |
2020 |
5-lipoxygenase pathway and its downstream cysteinyl leukotrienes as potential therapeutic targets for Alzheimer's disease. |
AA, AD |
16 |
2020 |
Aspirin-exacerbated respiratory disease. |
AERD, COX, IL-33, ILC2, PGE2 |
17 |
2020 |
Cellular interactions in aspirin-exacerbated respiratory disease. |
AERD, PGD2, PGE2 |
18 |
2020 |
Cellular Source of Cysteinyl Leukotrienes Following Chlorine Exposure. |
--- |
19 |
2020 |
Cysteinyl leukotriene D4 (LTD4) promotes airway epithelial cell inflammation and remodelling. |
ALI, BAL, HFD, LTD4, OVA, SAECs |
20 |
2020 |
Dysregulated metabolism of polyunsaturated fatty acids in eosinophilic allergic diseases. |
AA, DHA, ECRS, PUFAs |
21 |
2020 |
Exosomes from MSCs overexpressing microRNA-223-3p attenuate cerebral ischemia through inhibiting microglial M1 polarization mediated inflammation. |
CysLT2R, MCAO/R, OGD |
22 |
2020 |
Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1. |
CysLTR |
23 |
2020 |
Leukotriene D4 paradoxically limits LTC4-driven platelet activation and lung immunopathology. |
LT |
24 |
2020 |
Leukotriene D4 role in allergic asthma pathogenesis from cellular and therapeutic perspectives. |
--- |
25 |
2020 |
Modulation of neuroinflammation by cysteinyl leukotriene 1 and 2 receptors: implications for cerebral ischemia and neurodegenerative diseases. |
--- |
26 |
2020 |
Novel airway smooth muscle-mast cell interactions and a role for the TRPV4-ATP axis in non-atopic asthma. |
ASM, Ig, TRPV4 |
27 |
2020 |
Phase 2 trial of montelukast for prevention of pain in sickle cell disease. |
SCD |
28 |
2020 |
Targeting E. coli invasion of the blood-brain barrier for investigating the pathogenesis and therapeutic development of E. coli meningitis. |
EGFR |
29 |
2020 |
Trichomonas vaginalis-secreted cysteinyl leukotrienes promote migration, degranulation and MCP-1 production in mast cells. |
CysLTR, IL, LTB4, MCP-1, TvSP |
30 |
2020 |
Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity. |
IL-25 |
31 |
2020 |
Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study. |
MMA, PGs, SA |
32 |
2019 |
Adipocytokines leptin and adiponectin function as mast cell activity modulators. |
MCs, PI3K |
33 |
2019 |
Cysteinyl leukotriene 1 receptor expression in nasal polyps. |
CRS |
34 |
2019 |
Cysteinyl leukotriene metabolism of human eosinophils in allergic disease. |
--- |
35 |
2019 |
Cysteinyl leukotriene receptor 2 drives lung immunopathology through a platelet and high mobility box 1-dependent mechanism. |
AERD, HMGB1, LTC4, RAGE |
36 |
2019 |
Cysteinyl leukotriene receptor type 1 antagonist montelukast protects against injury of blood-brain barrier. |
BBB, EC, IL-1beta, IL-6, MMPs, OGD/R, TNF-alpha, ZO-1 |
37 |
2019 |
Cysteinyl maresins regulate the prophlogistic lung actions of cysteinyl leukotrienes. |
LMs, LT, MCTRs |
38 |
2019 |
Generation and phenotype analysis of CysLTR1 L118F mutant mice. |
CysLTR1 |
39 |
2019 |
Implications of prostaglandin D2 and leukotrienes in exhaled breath condensates of asthma. |
EBCs, LTB4, PGD2-MOX |
40 |
2019 |
Liquid chromatography-coupled mass spectrometry analysis of glutathione conjugates of oxygenated polyunsaturated fatty acids. |
AA, CTRs, DHA, EXs, LTC4, MCTRs, PCTRs, RCTRs |
41 |
2019 |
Roles of cysteinyl leukotrienes and their receptors in immune cell-related functions. |
LTC4 |
42 |
2019 |
RPTPepsilon promotes M2-polarized macrophage migration through ROCK2 signaling and podosome formation. |
HMDMs, LTD4, PTPepsilon |
43 |
2019 |
Suppression of aspirin-mediated eosinophil activation by prostaglandin E2: Relevance to aspirin and nonsteroidal anti-inflammatory drug hypersensitivity. |
AERD, EDN, LTB4, NSAIDs, PGE2 |
44 |
2019 |
The relationship between inflammatory markers and spirometric parameters in ACOS, Asthma, and COPD. |
COPD, IL-5, PGD2, PGE2 |
45 |
2019 |
Variants in the CYSLTR2 are associated with asthma, atopy markers and helminths infections in the Brazilian population. |
CYSLTR2 |
46 |
2018 |
A novel therapeutic potential of cysteinyl leukotrienes and their receptors modulation in the neurological complications associated with Alzheimer's disease. |
5-LOX, AD, LTC4, LTD4, LTE4 |
47 |
2018 |
Advanced Glycation End-Products-, C-Type Lectin- and Cysteinyl/ Leukotriene-Receptors in Distinct Mesenchymal Stromal Cell Populations: Differential Transcriptional Profiles in Response to Inflammation. |
AT, BM, FSK, LTB4, MSCs, qRT-PCR, WJ |
48 |
2018 |
Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes. |
CysLTR1, cysLTRs, OA, SA-beta-gal, TNF-alpha |
49 |
2018 |
Comparison of the efficacy and mechanisms of intranasal budesonide, montelukast, and their combination in treatment of patients with seasonal allergic rhinitis. |
BD, ECP, FeNO, MNT, NCV, SAR, Th1, Treg |
50 |
2018 |
CysLT1 receptor antagonist alleviates pathogenesis of collagen-induced arthritis mouse model. |
CIA, RA |
51 |
2018 |
Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis. |
ECs, LLC, VE |
52 |
2018 |
Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm. |
AAA, MIP-1alpha, MMP-9 |
53 |
2018 |
Cysteinyl leukotriene receptor 1 regulates glucose-stimulated insulin secretion (GSIS). |
cysLT1R, GSIS, RT-PCR |
54 |
2018 |
Edaravone, a free radical scavenger, protects neuronal cells' mitochondria from ischemia by inactivating another new critical factor of the 5-lipoxygenase pathway affecting the arachidonic acid metabolism. |
5-LOX, MCAO, OGD, OGD-R |
55 |
2018 |
House dust mite drives proinflammatory eicosanoid reprogramming and macrophage effector functions. |
AAI, aMDM, HDM, MDM |
56 |
2018 |
IL-33 Upregulates Cysteinyl Leukotriene Receptor Type 1 Expression in Human Peripheral Blood CD4+ T Lymphocytes. |
--- |
57 |
2018 |
Inhibition of 5-lipoxygenase inhibitor zileuton in high-fat diet-induced nonalcoholic fatty liver disease progression model. |
FFA, HE, HFD, NAFLD, NAS |
58 |
2018 |
Involvement and Possible Role of Eosinophils in Asthma Exacerbation. |
GM-CSF, ICAM, IL, LPS, RV, Th |
59 |
2018 |
Leukotriene E4 induces airflow obstruction and mast cell activation through the cysteinyl leukotriene type 1 receptor. |
CysLT1, LT, PG, TX |
60 |
2018 |
Lipid mediator Leukotriene D4-induces airway epithelial cells proliferation through EGFR/ERK1/2 pathway. |
EGF, LTD4, SAECs |
61 |
2018 |
Multi-Walled Carbon Nanotubes Augment Allergic Airway Eosinophilic Inflammation by Promoting Cysteinyl Leukotriene Production. |
HDM, MWCNT |
62 |
2018 |
Pathogenesis of NSAID-induced reactions in aspirin-exacerbated respiratory disease. |
AERD, PG |
63 |
2018 |
Targeting lipid mediators in asthma: time for reappraisal. |
CRTH2 |
64 |
2017 |
5-LO inhibition ameliorates palmitic acid-induced ER stress, oxidative stress and insulin resistance via AMPK activation in murine myotubes. |
5-LO, LTB4, PA |
65 |
2017 |
Cysteinyl leukotriene E4 activates human group 2 innate lymphoid cells and enhances the effect of prostaglandin D2 and epithelial cytokines. |
LT, PGD2, TSLP |
66 |
2017 |
Cysteinyl Leukotrienes as Potential Pharmacological Targets for Cerebral Diseases. |
--- |
67 |
2017 |
Cysteinyl Leukotrienes in Eosinophil Biology: Functional Roles and Therapeutic Perspectives in Eosinophilic Disorders. |
CysLT1R, CysLT2R, CysLTRs |
68 |
2017 |
Effects of leukotriene D4 nasal challenge on bronchial responsiveness and inflammation in asthmatic patients with allergic rhinitis. |
AR, BHR, FeNO, MCh |
69 |
2017 |
Expression of cysteinyl leukotriene receptor GPR17 in eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps. |
CRSwNP, ECRS, non-ECRS |
70 |
2017 |
High-affinity pan-specific monoclonal antibodies that target cysteinyl leukotrienes and show efficacy in an acute model of colitis. |
LTC4 |
71 |
2017 |
In Vivo Cysteinyl Leukotriene Release in Allergic and Nonallergic Immediate Hypersensitivity Reactions during Anesthesia. |
--- |
72 |
2017 |
Leukotriene C4 Potentiates IL-33-Induced Group 2 Innate Lymphoid Cell Activation and Lung Inflammation. |
LTC4 |
73 |
2017 |
Leukotriene D4 induces chemotaxis in human eosinophilc cell line, EoL-1 cells via CysLT1 receptor activation. |
--- |
74 |
2017 |
Leukotriene receptor antagonist attenuated airway inflammation and hyperresponsiveness in a double-stranded RNA-induced asthma exacerbation model. |
BAL, BALF, LTRA, OVA |
75 |
2017 |
Montelukast reduces inhaled chlorine triggered airway hyperresponsiveness and airway inflammation in the mouse. |
AHR, BAL |
76 |
2017 |
Prevalence of M75 Streptococcus pyogenes Strains Harboring slaA Gene in Patients Affected by Pediatric Obstructive Sleep Apnea Syndrome in Central Italy. |
GAS, MLST, OSAS, SLO |
77 |
2017 |
Prolonged, acute suppression of cysteinyl leukotriene to reduce capsular contracture around silicone implants. |
IF, TGF |
78 |
2017 |
Role of the Cysteinyl Leukotrienes in the Pathogenesis and Progression of Cardiovascular Diseases. |
5-LO |
79 |
2017 |
The inhibition of 5-Lipoxygenase (5-LO) products leukotriene B4 (LTB4) and cysteinyl leukotrienes (cysLTs) modulates the inflammatory response and improves cutaneous wound healing. |
5-LO, CysLT, LTB4 |
80 |
2017 |
The role of cysteinyl leukotrienes and their receptors in refractory nasal polyps. |
CRSsNP, CRSwNP, NPs, SEB |
81 |
2017 |
Type 2 Cysteinyl Leukotriene Receptors Drive IL-33-Dependent Type 2 Immunopathology and Aspirin Sensitivity. |
LTC4S |
82 |
2017 |
Urine cysteinyl leukotriene levels in children with sleep disordered breathing before and after adenotonsillectomy. |
OSA, SDB, uLTE4 |
83 |
2016 |
A dual CysLT1/2 antagonist attenuates allergen-induced airway responses in subjects with mild allergic asthma. |
EAR, FEV1, LAR |
84 |
2016 |
Advances in aspirin-exacerbated respiratory disease (AERD). |
AERD, COX, PGD2 |
85 |
2016 |
Aspirin Intolerance: Experimental Models for Bed-to-Bench. |
AERD, AIU, NSAID |
86 |
2016 |
CysLT1 Receptor Is Protective against Oxidative Stress in a Model of Irritant-Induced Asthma. |
cysLT1R, Nrf2, WT |
87 |
2016 |
Cysteinyl leukotriene correlated with 8-isoprostane levels as predictive biomarkers for sensory dysfunction in autism. |
CARS, ROC, SRS, SSP |
88 |
2016 |
Development of smart cell-free and cell-based assay systems for investigation of leukotriene C4 synthase activity and evaluation of inhibitors. |
5-LOX, AA, LTA4, LTC4S |
89 |
2016 |
Exhaled breath condensate pH and cysteinyl leukotriens in patients with chronic cough secondary to acid gastroesophageal reflux. |
EBC |
90 |
2016 |
Expression and localization of GPR99 in human nasal mucosa. |
--- |
91 |
2016 |
Leukotriene B4 receptor type 2 protects against pneumolysin-dependent acute lung injury. |
12-HHT, ALI, PLY |
92 |
2016 |
Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99. |
CysLTRs, EPC, LTC4, LTC4S, MC |
93 |
2016 |
Leukotriene E4 is a full functional agonist for human cysteinyl leukotriene type 1 receptor-dependent gene expression. |
CysLT1, ERK, LTE4 |
94 |
2016 |
Montelukast reduces seizures in pentylenetetrazol-kindled mice. |
PTZ |
95 |
2016 |
Paediatric obstructive sleep apnoea syndrome (OSAS) is associated with tonsil colonisation by Streptococcus pyogenes. |
GAS, MyD88, OSAS, SLO, TLR4, TMCs, TRIF |
96 |
2016 |
Preventive effect of genetic knockdown and pharmacological blockade of CysLT1R on lipopolysaccharide (LPS)-induced memory deficit and neurotoxicity in vivo. |
AD, LPS, MWM |
97 |
2016 |
Respiratory, ocular and skin health in recreational and competitive swimmers: Beneficial effect of a new method to reduce chlorine oxidant derivatives. |
EBC, LTB4 |
98 |
2016 |
Role of Cysteinyl Leukotrienes in Allergic Rhinitis. |
CysLT1R, CysLT2R |
99 |
2015 |
Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway. |
AERD, MCs |
100 |
2015 |
Cysteinyl Leukotrienes (CysLTs): Role in Obesity-Induced Asthma. |
5-LO, LTs |
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